Volume 9; Issue 15

Main
Bioorganic & Medicinal Chemistry Letters
Volume 9; Issue 15

Bioorganic & Medicinal Chemistry Letters

Volume 9; Issue 15

1

Highly sequence selective nonmacrocyclic two-armed receptors for peptides

Edward James Iorio, W.Clark Still

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1999

Language:

english

File:

PDF, 211 KB

english, 1999

2

Derivatives of (R)-2-amino-5-methoxytetralin: Antagonists and inverse agonists at the dopamine D2a receptor

Berit Backlund Höök, Cecilia Brege, Tero Linnanen, Åsa Mikaels, Åsa Malmberg, Anette M. Johansson

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1999

Language:

english

File:

PDF, 329 KB

english, 1999

3

Synthesis of heterocyclic enol ethers and their use as group 2 metabotropic glutamate receptor antagonists

Sabine Kolczewski, Geo Adam, Heinz Stadler, Vincent Mutel, Jürgen Wichmann, Thomas Woltering

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1999

Language:

english

File:

PDF, 162 KB

english, 1999

4

9-Deoxopodophyllotoxin derivatives as anti-cancer agents

Duvvuri Subrahmanyam, B. Renuka, G.Sunil Kumar, V. Vandana, Danvanthri S. Deevi

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1999

Language:

english

File:

PDF, 272 KB

english, 1999

5

Practical synthesis of all inositol stereoisomers from myo-inositol

Sung-Kee Chung, Yong-Uk Kwon

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1999

Language:

english

File:

PDF, 338 KB

english, 1999

6

Formation of 8-oxo-7,8-dihydro-2′-deoxyguanosine under anaerobic conditions by reductively activated nitro 5-deazaflavin derivatives

Yuji Mikata, Maki Kishigami, Mamiko Nishida, Shigenobu Yano, Tetsuji Kawamoto, Yoshihiro Ikeuchi, Fumio Yoneda

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1999

Language:

english

File:

PDF, 269 KB

english, 1999

7

Disproportionation reaction of disulfides promoted by nitric oxide (NO) in the presence of oxygen

Takashi Itoh, Nozomi Tsutsumi, Akio Ohsawa

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1999

Language:

english

File:

PDF, 299 KB

english, 1999

8

Casein kinase II inhibitors isolated form two Brazilian plants Hymenaea parvifolia and Wulffia baccata

Massmi Ishibashi, Hiroko Oda, Mana Mitamura, Emi Okuyama, Kanki Komiyama, Kiichiro Kawaguchi, Takashi Watanabe, Sérgio de Mello Alves, Toshiro Maekawa, Kenzo Ohtsuki

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1999

Language:

english

File:

PDF, 259 KB

english, 1999

9

Synthesis of pyrazolidinone antibacterial agents

Evanne Couloigner, Dominique Cartier, Roger Labie

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1999

Language:

english

File:

PDF, 105 KB

english, 1999

10

3-Alkyl-(5,5′-diphenyl)imidazolidinediones as new cannabinoid receptor ligands

Martial Kanyonyo, Sophie J. Govaerts, Emmanuel Hermans, Jacques H. Poupaert, Didier M. Lambert

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1999

Language:

english

File:

PDF, 237 KB

english, 1999

11

Design of peptides derived from anti-IgE antibody for allergic treatment

Mizuki Takahashi, Yasushi Ohgitani, Akihiko Ueno, Hisakazu Mihara

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1999

Language:

english

File:

PDF, 232 KB

english, 1999

12

Novel conformationally restricted tetracyclic analogs of Δ8-tetrahydrocannabinol

Atmaram D. Khanolkar, Dai Lu, Pusheng Fan, Xiaoyu Tian, Alexandros Makriyannis

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1999

Language:

english

File:

PDF, 298 KB

english, 1999

13

On-resin macrocyclization of peptides via intramolecular SnAr reactions

Christopher Fotsch, G. Kumaravel, Sushil K. Sharma, Arthur D. Wu, John S. Gounarides, N.R. Nirmala, Russell C. Petter

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1999

Language:

english

File:

PDF, 327 KB

english, 1999

14

Binding of Zn(II), Cu(II), and Fe(II) ions to alzheimer's Aß peptide studied by fluorescence

William Garzon-Rodriguez, Anatoly K. Yatsimirsky, Charles G. Glabe

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1999

Language:

english

File:

PDF, 318 KB

english, 1999

15

Synthesis of a N-acylsulfamide linked dinucleoside and its incorporation into an oligonucleotide

Jiancun Zhang, Mark D. Matteucci

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1999

Language:

english

File:

PDF, 180 KB

english, 1999

16

Structure-activity relationship of N-methyl-N-aralkyl-peptidylamines as novel N-type calcium channel blockers

Lain-Yen Hu, R. Todd Ryder, Michael F. Rafferty, David J. Dooley, Joann J. Geer, Susan M. Lotarski, George P. Miljanich, Elizabeth Millerman, David M. Rock, Sally J. Stoehr, Balazs G. Szoke, Charles P

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1999

Language:

english

File:

PDF, 250 KB

english, 1999

17

Nonpeptidic HIV protease inhibitors: 6-alkyl-5,6-dihydropyran-2-ones possessing a novel and achiral 3-(2-t-butyl-5-methyl-4-sulfamate)phenylthio moiety

J.V.N Vara Prasad, Larry J Markoski, Fred E Boyer, John M Domagala, Edmund L Ellsworth, Christopher Gajda, Susan E Hagen, Bradley D Tait, Elizabeth A Lunney, Peter J Tummino, Donna Ferguson, Tod Holle

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1999

Language:

english

File:

PDF, 336 KB

english, 1999

18

Novel quinolizidine salicylamide influenza fusion inhibitors

Kuo-Long Yu, Edward Ruediger, Guangxiang Luo, Christopher Cianci, Stephanie Danetz, Laurence Tiley, Ashok K. Trehan, Ivo Monkovic, Bradley Pearce, Alain Martel, Mark Krystal, Nicholas A. Meanwell

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1999

Language:

english

File:

PDF, 263 KB

english, 1999

19

Photonuclease activity of Taylor's blue

Taj Mohammad, Harry Morrison

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1999

Language:

english

File:

PDF, 392 KB

english, 1999

20

Targeting nitric oxide to cancer cells: cytotoxicity studies of glyco-S-nitrosothiols

Yongchun Hou, Jianqiang Wang, Peter R. Andreana, Guilleherme Cantauria, Srikumar Tarasia, Laura Sharp, Paul G. Braunschweiger, Peng G. Wang

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1999

Language:

english

File:

PDF, 230 KB

english, 1999

21

7-Amino-4-methyl-6-sulfocoumarin-3-acetic acid: a novel blue fluorescent dye for protein labeling

Wai-Yee Leung, Patty A. Trobridge, Rosaria P. Haugland, Richard P. Haugland, Fei Mao

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1999

Language:

english

File:

PDF, 162 KB

english, 1999

22

SAR in the alkoxy lactone series: the discovery of DFP, a potent and orally active COX-2 inhibitor

Y. Leblanc, P. Roy, S. Boyce, C. Brideau, C.C. Chan, S. Charleson, R. Gordon, E. Grimm, J. Guay, S. Léger, C.S. Li, D. Riendeau, D. Visco, Z. Wang, J. Webb, L.J. Xu, P. Prasit

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1999

Language:

english

File:

PDF, 295 KB

english, 1999

23

Dimethyldioxirane epoxidation of polycyclic fluoranthene hydrocarbons

Fushuang Liu, Bongsup P. Cho

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1999

Language:

english

File:

PDF, 237 KB

english, 1999

24

Increased antiviral activity of cyclic urea HIV protease inhibitors by modifying the P1/P1′ substituents

Robert F. Kaltenbach, Ronald M. Klabe, Beverly C. Cordova, Steven P. Seitz

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1999

Language:

english

File:

PDF, 187 KB

english, 1999

25

Structure-based design of irreversible, tripeptidyl human rhinovirus 3C protease inhibitors containing N-methyl amino acids

Peter S Dragovich, Stephen E Webber, Thomas J Prins, Ru Zhou, Joseph T Marakovits, Jayashree G Tikhe, Shella A Fuhrman, Amy K Patick, David A Matthews, Clifford E Ford, Edward L Brown, Susan L Binford

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1999

Language:

english

File:

PDF, 336 KB

english, 1999

26

Novel quinolinequinone antitumor agents: Structure-metabolism studies with NAD(P)H:quinone oxidoreductase (NQO1)

Tara Fryatt, Dean T. Goroski, Zachary D. Nilson, Christopher J. Moody, Howard D. Beall

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1999

Language:

english

File:

PDF, 191 KB

english, 1999

27

Synthesis and biological evaluation of a new class of vaccine adjuvants: aminoalkyl glucosaminide 4-phosphates (AGPs)

David A. Johnson, C. Gregory Sowell, Craig L. Johnson, Mark T. Livesay, David S. Keegan, Michael J. Rhodes, J. Terry Ulrich, Jon R. Ward, John L. Cantrell, Valerie G. Brookshire

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1999

Language:

english

File:

PDF, 394 KB

english, 1999

28

Novel protein kinase C inhibitors: synthesis and PKC inhibition of β-substituted polythiophene derivatives

Wei-Chu Xu, Qin Zhou, Curtis L. Ashendel, Ching-te Chang, Ching-jer Chang

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1999

Language:

english

File:

PDF, 211 KB

english, 1999

29

Total synthesis of the-potent proteasome inhibitor epoxomicin: a useful tool for understanding proteasome biology

Ny Sin, Kyung Bo Kim, Mikael Elofsson, Lihao Meng, Hak Auth, Benjamin H.B. Kwok, Craig M. Crews

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1999

Language:

english

File:

PDF, 411 KB

english, 1999

30

Human chymase inhibitors based on the 1,2,5-thiadiazolidin-3-one 1,1 dioxide scaffold

William C. Groutas, Norman M. Schechter, Shu He, Hongyi Yu, Peng Huang, Juan Tu

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1999

Language:

english

File:

PDF, 277 KB

english, 1999

31

Ring E analogs of methyllycaconitine (MLA) as novel nicotinic antagonists

Stephen C. Bergmeier, David J. Lapinsky, R.Benjamin Free, Dennis B McKay

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1999

Language:

english

File:

PDF, 296 KB

english, 1999

32

Significant compensatory role of position Y-2 conferring high affinity to non-phosphorylated inhibitors of Grb2-SH2 domain

Ya-Qiu Long, Johannes H. Voigt, Feng-Di T. Lung, C.Richter King, Peter P. Roller

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1999

Language:

english

File:

PDF, 328 KB

english, 1999

33

Triterpene and diterpene inhibitors of pyruvate dehydrogenase kinase (PDK)

Thomas D. Aicher, Robert E. Damon, Judit Koletar, Christine C. Vinluan, Leonard J. Brand, Jiaping Gao, Suraj S. Shetty, Emma L. Kaplan, William R. Mann

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1999

Language:

english

File:

PDF, 337 KB

english, 1999

34

A 2-nitroimidazole carbamate prodrug of 5-amino-1-(chloromethyl)-3-[(5,6,7-trimethoxyindol-2-yl)carbonyl]-1,2-dihydro-3H-benz[e]indole (amino-seco-CBI-TMI) for use with ADEPT and GDEPT

Michael P. Hay, Bridget M. Sykes, William A. Denny, William R. Wilson

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1999

Language:

english

File:

PDF, 341 KB

english, 1999

35

Contributors to this issue

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1999

Language:

english

File:

PDF, 103 KB

english, 1999

36

Graphical abstracts

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1999

Language:

english

File:

PDF, 512 KB

english, 1999