Volume 99

Bioorganic Chemistry

Volume 99

1

Efficient synthesis of Î²-lactam antibiotics with in situ product removal by a newly isolated penicillin G acylase

Pan, Xin, Li, Anni, Peng, Zhiyi, Ji, Xiaoqi, Chu, Jianlin, He, Bingfang

Journal:

Bioorganic Chemistry

Year:

2020

Language:

english

File:

PDF, 3.06 MB

english, 2020

2

Biogenic synthesis of silica nanoparticles from corn cobs husks. Dependence of the productivity on the method of raw material processing

PieÅa, Aleksandra, Å»ymaÅczyk-Duda, Ewa, BrzeziÅska-Rodak, MaÅgorzata, Duda, Maciej, Grzesiak, Jakub, Saeid, Agnieszka, Mironiuk, MaÅgorzata, Klimek-Ochab, Magdalena

Journal:

Bioorganic Chemistry

Year:

2020

Language:

english

File:

PDF, 13.23 MB

english, 2020

3

Separation and identification of enzyme inhibition peptides from dark tea protein

Zhao, Bingli, Su, Keying, Mao, Xinliang, Zhang, Xuewu

Journal:

Bioorganic Chemistry

Year:

2020

Language:

english

File:

PDF, 4.41 MB

english, 2020

4

Benzimidazoquinazolines as new potent anti-TB chemotypes: Design, synthesis, and biological evaluation

Jadhavar, Pradeep S., Patel, Kshitij I., Dhameliya, Tejas M., Saha, Nirjhar, Vaja, Maulikkumar D., Krishna, Vagolu Siva, Sriram, Dharmarajan, Chakraborti, Asit K.

Journal:

Bioorganic Chemistry

Year:

2020

Language:

english

File:

PDF, 1.05 MB

english, 2020

5

Synthesis of 2-methoxy-3-(thiophen-2-ylmethyl)quinoline containing amino carbinols as antitubercular agents

Karkara, Bidhu Bhusan, Mishra, Shashank Shekhar, Singh, Bhupendra N., Panda, Gautam

Journal:

Bioorganic Chemistry

Year:

2020

Language:

english

File:

PDF, 761 KB

english, 2020

6

Development and biological investigations of hypoxia-sensitive prodrugs of the tyrosine kinase inhibitor crizotinib

Bielec, Bjoern, Schueffl, Hemma, Terenzi, Alessio, Berger, Walter, Heffeter, Petra, Keppler, Bernhard K., Kowol, Christian R.

Journal:

Bioorganic Chemistry

Year:

2020

Language:

english

File:

PDF, 7.36 MB

english, 2020

7

A review on progression of epidermal growth factor receptor (EGFR) inhibitors as an efficient approach in cancer targeted therapy

Ayati, Adileh, Moghimi, Setareh, Salarinejad, Somayeh, Safavi, Maliheh, Pouramiri, Behjat, Foroumadi, Alireza

Journal:

Bioorganic Chemistry

Year:

2020

File:

PDF, 1.15 MB

2020

8

Synthesis of symmetrical bis-Schiff base-disulfide hybrids as highly effective anti-leishmanial agents

Taha, Muhammad, Sain, Amyra Amat, Ali, Muhammad, Anouar, El Hassane, Rahim, Fazal, Ismail, Nor Hadiani, Adenan, Mohd Ilham, Imran, Syahrul, Al-Harrasi, Ahmed, Nawaz, Fasial, Iqbal, Naveed, Khan, Khali

Journal:

Bioorganic Chemistry

Year:

2020

File:

PDF, 1.13 MB

2020

9

Biocatalytic allylic hydroxylation of unsaturated triterpenes and steroids by Bacillus megaterium CGMCC 1.1741

Wang, Wei, Wang, Weiwei, Ge, Haixia, Li, Guolong, Shen, Pingping, Xu, Shaohua, Yu, Boyang, Zhang, Jian

Journal:

Bioorganic Chemistry

Year:

2020

File:

PDF, 582 KB

2020

10

Quinazoline-4(3H)-one derivatives as novel and potent inhibitors of soluble epoxide hydrolase: Design, synthesis and biological evaluation

Hejazi, Leila, Rezaee, Elham, Tabatabai, Sayyed Abbas

Journal:

Bioorganic Chemistry

Year:

2020

File:

PDF, 2.31 MB

2020

11

Novel functionally substituted esters based on sodium diethyldithiocarbamate derivatives: Synthesis, characterization, biological activity and molecular docking studies

Karimov, Alverdi, Orujova, Arzu, Taslimi, Parham, Sadeghian, Nastaran, Mammadov, Bahtiyar, Karaman, Halide Sedef, Farzaliyev, Vagif, Sujayev, Afsun, Tas, Recep, Alwasel, Saleh, GulÃ§in, Ä°lhami

Journal:

Bioorganic Chemistry

Year:

2020

File:

PDF, 3.31 MB

2020

12

The anti-inflammatory components from the effective fraction of Syringae Folium (ESF) and its mechanism investigation based on network pharmacology

Wang, Yuwei, Zhou, Zhengyuan, Han, Mingshu, Zhai, Jianxiu, Han, Na, Liu, Zhihui, Yin, Jun

Journal:

Bioorganic Chemistry

Year:

2020

File:

PDF, 3.93 MB

2020

13

Tubulin inhibitors: Discovery of a new scaffold targeting extra-binding residues within the colchicine site through anchoring substituents properly adapted to their pocket by a semi-flexible linker

Maklad, Raed M., AbdelHafez, El-Shimaa M.N., Abdelhamid, Dalia, Aly, Omar M.

Journal:

Bioorganic Chemistry

Year:

2020

File:

PDF, 2.97 MB

2020

14

A trisaccharide phenylethanoid glycoside from Scrophularia flava Grau with potential anti-type 2 diabetic properties by inhibiting Î±-glucosidase enzyme and decreasing oxidative stress

Hamedi, Azadeh, Pasdaran, Ardalan, Pasdaran, Arsalan

Journal:

Bioorganic Chemistry

Year:

2020

File:

PDF, 1.62 MB

2020

15

Synthesis, characterization, antimicrobial and DNA binding properties of an organic charge transfer complex obtained from pyrazole and chloranilic acid

Khan, Ishaat M., Islam, Maidul, Shakya, Sonam, Alam, Kehkashan, Alam, Nisat, Shahid, M.

Journal:

Bioorganic Chemistry

Year:

2020

File:

PDF, 8.52 MB

2020

16

Design, synthesis, in vitro and in silico studies of 2, 3-diaryl benzofuran derivatives as antitubercular agents

Bhukya, Balakishan, Shukla, Aparna, Chaturvedi, Vinita, Trivedi, Priyanka, Kumar, Shailesh, Khan, Feroz, Negi, Arvind S., Srivastava, Santosh Kumar

Journal:

Bioorganic Chemistry

Year:

2020

File:

PDF, 5.92 MB

2020

17

Guaiane type of sesquiterpene with NO inhibitory activity from the root of Wikstroemia indica

Liu, Zhihui, Dong, Mengyu, Chang, Hang, Han, Na, Yin, Jun

Journal:

Bioorganic Chemistry

Year:

2020

File:

PDF, 1.60 MB

2020

18

Synthesis of N-substituted indole derivatives as potential antimicrobial and antileishmanial agents

Tiwari, Shweta, Kirar, Seema, Banerjee, Uttam Chand, Neerupudi, Kishore Babu, Singh, Sushma, Wani, Aabid Abdullah, Bharatam, Prasad V., Singh, Inder Pal

Journal:

Bioorganic Chemistry

Year:

2020

File:

PDF, 1.03 MB

2020

19

Polyphyllosides AâF, six new spirostanol saponins from the stems and leaves of Paris polyphylla var. chinensis

Qin, Xu-Jie, Zhang, Lan-Jun, Zhang, Yu, Ni, Wei, Yang, Xing-Zhi, Yu, Qian, Yan, Huan, An, Lin-Kun, Liu, Hai-Yang

Journal:

Bioorganic Chemistry

Year:

2020

File:

PDF, 1.91 MB

2020

20

Anti-inflammatory 5,6,7,8-tetrahydro-2-(2-phenylethyl)chromones from agarwood of Aquilaria sinensis

Yu, Zhangxin, Wang, Canhong, Zheng, Wei, Chen, Deli, Liu, Yangyang, Yang, Yun, Wei, Jianhe

Journal:

Bioorganic Chemistry

Year:

2020

File:

PDF, 1.55 MB

2020

21

Identification of N-acyl quinolin-2(1H)-ones as new selective agents against clinical isolates of Acanthamoeba keratitis

Reyes-Batlle, MarÃa, Freijo, MÃ³nica Blanco, LÃ³pez-Arencibia, Atteneri, Lorenzo-Morales, Jacob, McNaughton-Smith, Grant, PiÃ±ero, JosÃ© E., Abad-Grillo, Teresa

Journal:

Bioorganic Chemistry

Year:

2020

File:

PDF, 1.11 MB

2020

22

Dexamethasone simulates the anticancer effect of nano-formulated paclitaxel in breast cancer cells

Diab, Thoria, AlKafaas, Samar Sami, Shalaby, Thanaa Ibrahim, Hessien, Mohamed

Journal:

Bioorganic Chemistry

Year:

2020

File:

PDF, 4.82 MB

2020

23

Synthesis and cytotoxic activities of organometallic Ru(II) diamine complexes

Kavukcu, Serdar BatÄ±kan, Åahin, Onur, Seda Vatansever, Hafize, Kurt, Feyzan Ozdal, Korkmaz, Mehmet, Kendirci, Remziye, Pelit, Levent, TÃ¼rkmen, Hayati

Journal:

Bioorganic Chemistry

Year:

2020

File:

PDF, 3.86 MB

2020

24

Design, synthesis and biological evaluation of novel 2,4-bismorpholinothieno[3,2-d]pyrimidine and 2-morpholinothieno[3,2-d]pyrimidinone derivatives as potent antitumor agents

Ye, Tianyu, Han, Yufei, Wang, Ruxin, Yan, Pingzhen, Chen, Shaowei, Hou, Yunlei, Zhao, Yanfang

Journal:

Bioorganic Chemistry

Year:

2020

File:

PDF, 7.52 MB

2020

25

Design, synthesis and anticancer activity of novel valproic acid conjugates with improved histone deacetylase (HDAC) inhibitory activity

Ibrahim, Tarek S., Sheha, Taghreed A., Abo-Dya, Nader E., AlAwadh, Mohammed A., Alhakamy, Nabil A., Abdel-Samii, Zakaria K., Panda, Siva S., Abuo-Rahma, Gamal El-Din A., Mohamed, Mamdouh F.A.

Journal:

Bioorganic Chemistry

Year:

2020

File:

PDF, 7.60 MB

2020

26

2-Anilinopyrimidine derivatives: Design, synthesis, in vitro anti-proliferative activity, EGFR and ARO inhibitory activity, cell cycle analysis and molecular docking study

AboulWafa, Omaima M., Daabees, Hoda M.G., Badawi, Waleed A.

Journal:

Bioorganic Chemistry

Year:

2020

File:

PDF, 6.36 MB

2020

27

Anti-tubercular activity of novel class of spiropyrrolidine tethered indenoquinoxaline heterocyclic hybrids

Arumugam, Natarajan, Almansour, Abdulrahman I., Suresh Kumar, Raju, Ibrahim Alaqeel, Shatha, Siva Krishna, Vagolu, Sriram, Dharmarajan

Journal:

Bioorganic Chemistry

Year:

2020

File:

PDF, 1.08 MB

2020

28

Discovery and optimization of novel phenyldiazepine and pyridodiazepine based Aurora kinase inhibitors

Tamizharasan, Natarajan, Gajendran, Chandru, Kristam, Rajendra, Sulochana, Suresh P., Sivanandhan, Dhanalakshmi, Mullangi, Ramesh, Mathivathanan, Logesh, Hallur, Gurulingappa, Suresh, Palaniswamy

Journal:

Bioorganic Chemistry

Year:

2020

File:

PDF, 1.94 MB

2020

29

An assessment study of known pyrazolopyrimidines: Chemical methodology and cellular activity

Rao, R. Nishanth, Chanda, Kaushik

Journal:

Bioorganic Chemistry

Year:

2020

File:

PDF, 7.53 MB

2020

30

Structural modifications of amino acid sequences of radiolabeled peptides for targeted tumor imaging

Maleki, Fariba, Farahani, Arezou Masteri, Rezazedeh, Farzaneh, Sadeghzadeh, Nourollah

Journal:

Bioorganic Chemistry

Year:

2020

File:

PDF, 1.09 MB

2020

31

Discovery of novel dual PPARÎ±/Î´ agonists based on benzimidazole scaffold for the treatment of non-alcoholic fatty liver disease

Li, Zheng, Xu, Yawen, Cai, Zongyu, Wang, Xuekun, Ren, Qiang, Zhou, Zongtao, Xie, Rongrong

Journal:

Bioorganic Chemistry

Year:

2020

File:

PDF, 6.65 MB

2020

32

Synthesis and anti-hepaticfibrosis of glycyrrhetinic acid derivatives with inhibiting COX-2

Zhang, Qiuping, Mohammed, Eyad Abdulwhab Hamoud, Wang, Yanni, Bai, Zhongjie, Zhao, Quanyi, He, Dian, Wang, Zhen

Journal:

Bioorganic Chemistry

Year:

2020

File:

PDF, 11.44 MB

2020

33

Novel 2-amino-4-aryl-6-pyridopyrimidines and N-alkyl derivatives: Synthesis, characterization and investigation of anticancer, antibacterial activities and DNA/BSA binding affinities

Kahriman, Nuran, Peker, KÄ±vanÃ§, SerdaroÄlu, Vildan, AydÄ±n, Ali, Usta, Asu, FandaklÄ±, Seda, YaylÄ±, Nurettin

Journal:

Bioorganic Chemistry

Year:

2020

File:

PDF, 5.19 MB

2020

34

1,2,4-Triazolin-5-thione derivatives with anticancer activity as CK1Î³ kinase inhibitors

Pitucha, Monika, Janeczko, Monika, Klimek, Katarzyna, Fornal, Emilia, Wos, Maciej, Pachuta-Stec, Anna, Ginalska, Grazyna, Kaczor, Agnieszka A.

Journal:

Bioorganic Chemistry

Year:

2020

File:

PDF, 6.15 MB

2020

35

Discovery of novel multi-substituted benzo-indole pyrazole schiff base derivatives with antibacterial activity targeting DNA gyrase

Liu, Hao, Chu, Zhi-Wen, Xia, Dong-Guo, Cao, Hai-Qun, Lv, Xian-Hai

Journal:

Bioorganic Chemistry

Year:

2020

File:

PDF, 2.07 MB

2020

36

Alopecines AâE, five chloro-containing matrine-type alkaloids with immunosuppressive activities from the seeds of Sophora alopecuroides

Wang, Xiao-Feng, Zhu, Zhengdan, Hao, Ting-Ting, Fang, Qiang-Qiang, Jiang, Kun, Qu, Shi-Jin, Zuo, Jiang-Pin, Zhu, Weiliang, He, Shi-Jun, Tan, Chang-Heng

Journal:

Bioorganic Chemistry

Year:

2020

File:

PDF, 859 KB

2020

37

Pyridazino[1,6-b]quinazolinones as new anticancer scaffold: Synthesis, DNA intercalation, topoisomerase I inhibition and antitumor evaluation in vitro and in vivo

Huang, Wan-Yun, Zhang, Xiao-Rong, Lyu, Liang, Wang, Shu-Qin, Zhang, Xiao-Ting

Journal:

Bioorganic Chemistry

Year:

2020

File:

PDF, 5.58 MB

2020

38

New secondary metabolites with immunosuppressive activity from the phytopathogenic fungus Bipolaris maydis

Duan, Xueyan, Tan, Xiaosheng, Gu, Lianghu, Liu, Junjun, Hao, Xincai, Tao, Li, Feng, Hao, Cao, Yunfang, Shi, Zhengyi, Duan, Yulin, Deng, Mengyi, Chen, Gang, Qi, Changxing, Zhang, Yonghui

Journal:

Bioorganic Chemistry

Year:

2020

File:

PDF, 650 KB

2020

39

Development of small-molecule BRD4 degraders based on pyrrolopyridone derivative

Zhang, Jian, Chen, Pan, Zhu, Peiyu, Zheng, Peiyuan, Wang, Tao, Wang, Lixun, Xu, Changliang, Zhou, Jinpei, Zhang, Huibin

Journal:

Bioorganic Chemistry

Year:

2020

File:

PDF, 1.70 MB

2020

40

Redox cycling of copper by coumarin-di(2-picolyl)amine hybrid molecule leads to ROS-mediated modulation of redox scavengers, DNA damage and cell death in diethylnitrosamine induced hepatocellular carcinoma

Khan, Saman, Zafar, Atif, Naseem, Imrana

Journal:

Bioorganic Chemistry

Year:

2020

File:

PDF, 4.69 MB

2020

41

Synthesis of fluorescent G-quadruplex DNA binding ligands for the comparison of terminal group effects in molecular interaction: Phenol versus methoxybenzene

Jin, Jingwei, Hou, Jinqiang, Long, Wei, Zhang, Xinyue, Lu, Yu-Jing, Li, Dongli, Zhang, Kun, Wong, Wing-Leung

Journal:

Bioorganic Chemistry

Year:

2020

File:

PDF, 2.60 MB

2020

42

The rise of gingerol as anti-QS molecule: Darkest episode in the LuxR-mediated bioluminescence saga

Parmar, Paritosh, Shukla, Arpit, Rao, Priyashi, Saraf, Meenu, Patel, Baldev, Goswami, Dweipayan

Journal:

Bioorganic Chemistry

Year:

2020

File:

PDF, 7.90 MB

2020

43

Privileged scaffold inspired design of novel oxime-biphenyl-DAPYs in treatment of HIV-1

Yang, Yang, Pannecouque, Christophe, Clercq, Erik De, Zhuang, Chunlin, Chen, Fen-Er

Journal:

Bioorganic Chemistry

Year:

2020

File:

PDF, 1.77 MB

2020

44

Design and synthesis of 3,5-substituted 1,2,4-oxadiazoles as catalytic inhibitors of human DNA topoisomerase IIÎ±

Loboda, Kaja Bergant, Valjavec, Katja, Å tampar, Martina, Wolber, Gerhard, Å½egura, Bojana, FilipiÄ, Metka, Dolenc, Marija Sollner, Perdih, Andrej

Journal:

Bioorganic Chemistry

Year:

2020

File:

PDF, 2.57 MB

2020

45

Exploring bulky natural and natural-like periphery in the design of p-(benzyloxy)phenylpropionic acid agonists of free fatty acid receptor 1 (GPR40)

Kuranov, Sergey O., Luzina, Olga A., Onopchenko, Oleksandra, Pishel, Iryna, Zozulya, Sergey, Gureev, Maxim, Salakhutdinov, Nariman F., Krasavin, Mikhail

Journal:

Bioorganic Chemistry

Year:

2020

File:

PDF, 1.95 MB

2020

46

New 1Z,5Z-diene macrodiolides: Catalytic synthesis, anticancer activity, induction of mitochondrial apoptosis, and effect on the cell cycle

Dzhemileva, Lilya U., D'yakonov, Vladimir A., Islamov, Ilgiz I., Yunusbaeva, Milyausha M., Dzhemilev, Usein M.

Journal:

Bioorganic Chemistry

Year:

2020

File:

PDF, 1.87 MB

2020

47

Synthesis, distribution analysis and mechanism studies of N-acyl glucosamine-bearing oleanolic saponins

Juang, Yu-Pu, Lin, You-Yu, Chan, She-Hung, Chang, Chun-Kai, Shie, Jiun-Jie, Hsieh, Yves S.Y., Guh, Jih-Hwa, Liang, Pi-Hui

Journal:

Bioorganic Chemistry

Year:

2020

File:

PDF, 2.16 MB

2020

48

Optimization of activity localization of quinoline derivatives: Design, synthesis, and dual evaluation of biological activity for potential antitumor and antibacterial agents

Jin, Guofan, Li, Zhenwang, Xiao, Fuyan, Qi, Xueyong, Sun, Xianyu

Journal:

Bioorganic Chemistry

Year:

2020

File:

PDF, 1.54 MB

2020

49

Synthesis and carbonic anhydrase inhibition studies of sulfonamide based indole-1,2,3-triazole chalcone hybrids

Singh, Priti, Swain, Baijayantimala, Thacker, Pavitra S., Sigalapalli, Dilep Kumar, Purnachander Yadav, P., Angeli, Andrea, Supuran, Claudiu T., Arifuddin, Mohammed

Journal:

Bioorganic Chemistry

Year:

2020

File:

PDF, 889 KB

2020

50

Antimicrobial evaluation of thiadiazino and thiazolo quinoxaline hybrids as potential DNA gyrase inhibitors; design, synthesis, characterization and morphological studies

Ammar, Yousry A., Farag, Awatef A., Ali, Abeer M., Hessein, Sadia A., Askar, Ahmed A., Fayed, Eman A., Elsisi, Doaa M., Ragab, Ahmed

Journal:

Bioorganic Chemistry

Year:

2020

File:

PDF, 4.03 MB

2020

51

N-Trifluoroacetylated pyrazolines: Synthesis, characterization and antimicrobial studies

Asad, Mohammad, Arshad, Muhammad Nadeem, Oves, Mohammad, Khalid, Muhammad, Khan, Salman A., Asiri, Abdullah M., Rehan, Mohd, Dzudzevic-Cancar, Hurija

Journal:

Bioorganic Chemistry

Year:

2020

File:

PDF, 1.79 MB

2020

52

Fluorinated CRA13 analogues: Synthesis, in vitro evaluation, radiosynthesis, in silico and in vivo PET study

Hassan, Ahmed H.E., Park, Kyung Tae, Kim, Hye Jin, Lee, Hyo Jong, Kwon, Yeong Ho, Hwang, Ji Young, Jang, Choon-Gon, Chung, Jin Hwa, Park, Ki Duk, Lee, Sang Joo, Oh, Seung Jun, Lee, Yong Sup

Journal:

Bioorganic Chemistry

Year:

2020

File:

PDF, 2.25 MB

2020

53

Discovery of novel pyrazoline derivatives containing methyl-1H-indole moiety as potential inhibitors for blocking APC-Asef interactions

Qi, Peng-Fei, Fang, Li, Li, Hua, Li, Shu-Kai, Yang, Yu-Shun, Qi, Jin-Liang, Xu, Chen, Zhu, Hai-Liang

Journal:

Bioorganic Chemistry

Year:

2020

File:

PDF, 1.30 MB

2020

54

PCR incorporation of dUMPs modified with aromatic hydrocarbon substituents of different hydrophilicities: Synthesis of C5-modified dUTPs and PCR studies using Taq, Tth, Vent (exo-) and Deep Vent (exo-) polymerases

Zasedateleva, Olga A., Surzhikov, Sergey A., Shershov, Valeriy E., Miftakhov, Rinat A., Yurasov, Dmitry A., Kuznetsova, Viktoriya E., Chudinov, Alexander V.

Journal:

Bioorganic Chemistry

Year:

2020

File:

PDF, 1.40 MB

2020

55

Drug discovery approaches targeting the incretin pathway

Deng, Xinxian, Tavallaie, Mojdeh S., Sun, Ran, Wang, Juntao, Cai, Qingqing, Shen, Jian, Lei, Shuwen, Fu, Lei, Jiang, Faqin

Journal:

Bioorganic Chemistry

Year:

2020

File:

PDF, 5.89 MB

2020

56

Design, synthesis and biological evaluation of novel carboline-cinnamic acid hybrids as multifunctional agents for treatment of Alzheimerâs disease

Liao, Qinghong, Li, Qi, Zhao, Yifan, Jiang, Pan, Yan, Yuhui, Sun, Haopeng, Liu, Wenyuan, Feng, Feng, Qu, Wei

Journal:

Bioorganic Chemistry

Year:

2020

File:

PDF, 2.32 MB

2020

57

Synthesis of two novel pyrazolo[1,5-a]pyrimidine compounds with antibacterial activity and biophysical insights into their interactions with plasma protein

He, Ling-Ling, Qi, Qi, Wang, Xin, Li, Yu, Zhu, Yao, Wang, Xiao-Fang, Xu, Liang

Journal:

Bioorganic Chemistry

Year:

2020

File:

PDF, 8.19 MB

2020

58

Synthesis of new hetero-arylidene-9(10H)-anthrone derivatives and their biological evaluation

Roma-Rodrigues, Catarina, Malta, Gabriela, Peixoto, Daniela, Ferreira, LuÃsa M., Baptista, Pedro V., Fernandes, Alexandra R., Branco, Paula S.

Journal:

Bioorganic Chemistry

Year:

2020

File:

PDF, 1.47 MB

2020

59

Synthesis, biological evaluation and preclinical study of a novel 99mTc-peptide: A targeting probe of amyloid-Î² plaques as a possible diagnostic agent for Alzheimerâs disease

Jokar, Safura, Behnammanesh, Hossein, Erfani, Mostafa, Sharifzadeh, Mohammad, Gholami, Mahdi, Sabzevari, Omid, Amini, Mohsen, Geramifar, Parham, Hajiramezanali, Maliheh, Beiki, Davood

Journal:

Bioorganic Chemistry

Year:

2020

File:

PDF, 1.62 MB

2020

60

A drug-like imidazole-benzothiazole conjugate inhibits malignant melanoma by stabilizing the c-MYC G-quadruplex

Wu, Tian-Ying, Huang, Qiong, Huang, Zhi-Shu, Hu, Ming-Hao, Tan, Jia-Heng

Journal:

Bioorganic Chemistry

Year:

2020

File:

PDF, 4.06 MB

2020

61

Physicochemical and in vitro cytotoxicity studies of inclusion complex between gemcitabine and cucurbit[7]uril host

Buczkowski, Adam, Gorzkiewicz, MichaÅ, Stepniak, Artur, Malinowska-Michalak, MaÅgorzata, Tokarz, PaweÅ, Urbaniak, PaweÅ, Ionov, Maksim, Klajnert-Maculewicz, Barbara, Palecz, Bartlomiej

Journal:

Bioorganic Chemistry

Year:

2020

File:

PDF, 2.39 MB

2020

62

Bromocoumarinplatin, targeting simultaneously mitochondria and nuclei with p53 apoptosis pathway to overcome cisplatin resistance

Ma, Jing, Li, Linrong, Yue, Kexin, Li, Yingguang, Liu, Hanfang, Wang, Peng George, Wang, Chaojie, Wang, Jiajia, Luo, Wen, Xie, Songqiang

Journal:

Bioorganic Chemistry

Year:

2020

File:

PDF, 1.20 MB

2020

63

Gold nanoparticles morphology does not affect the multivalent presentation and antibody recognition of Group A Streptococcus synthetic oligorhamnans

Pitirollo, Olimpia, Micoli, Francesca, Necchi, Francesca, Mancini, Francesca, Carducci, Martina, Adamo, Roberto, Evangelisti, Claudio, Morelli, Laura, Polito, Laura, Lay, Luigi

Journal:

Bioorganic Chemistry

Year:

2020

File:

PDF, 1.46 MB

2020

64

Seven pairs of new enantiomeric sesquiterpenoids from Curcuma phaeocaulis

Liu, Fei, Chen, Jin-Feng, Qiao, Ming-Ming, Zhao, Hao-Yu, Zhou, Qin-Mei, Guo, Li, Peng, Cheng, Xiong, Liang

Journal:

Bioorganic Chemistry

Year:

2020

File:

PDF, 2.07 MB

2020

65

Design, synthesis, and evaluation of novel CXCR4 antagonists based on an aminoquinoline template

Lin, Yu, Li, Zhanhui, Xu, Chen, Xia, Kaijiang, Wu, Shuwei, Hao, Yongjin, Yang, Qing, Ma, Haikuo, Zheng, Jiyue, Luo, Lusong, Zhu, Fang, He, Sudan, Zhang, Xiaohu

Journal:

Bioorganic Chemistry

Year:

2020

File:

PDF, 1.09 MB

2020

66

Newly reported alkaloids produced by marine-derived Penicillium species (covering 2014â2018)

Zhang, Peng, Wei, Qian, Yuan, Xiaolong, Xu, Kuo

Journal:

Bioorganic Chemistry

Year:

2020

File:

PDF, 1.52 MB

2020

67

Identification of new therapeutic targets and natural compounds against diffuse intrinsic pontine glioma (DIPG)

Chen, Jungang, Lin, Zhen, Barrett, Lindsey, Dai, Lu, Qin, Zhiqiang

Journal:

Bioorganic Chemistry

Year:

2020

File:

PDF, 3.53 MB

2020

68

From nucleus to mitochondria to lysosome selectivity switching in a cyanine probe: The phenolic to methoxy substituent conversion affects probeâs selectivity

Abeywickrama, Chathura S., Bertman, Keti A., Pang, Yi

Journal:

Bioorganic Chemistry

Year:

2020

File:

PDF, 3.30 MB

2020

69

Discovery of diaminopyrimidine-carboxamide derivatives as JAK3 inhibitors

Bahekar, Rajesh, Panchal, Nandini, Soman, Shubhangi, Desai, Jigar, Patel, Dipam, Argade, Anil, Gite, Archana, Gite, Sanjay, Patel, Bhaumin, Kumar, Jeevan, S, Sachchidanand, Patel, Harilal, Sundar, Raj

Journal:

Bioorganic Chemistry

Year:

2020

File:

PDF, 1.16 MB

2020

70

Exploiting oxadiazole-sulfonamide hybrids as new structural leads to combat diabetic complications via aldose reductase inhibition

Javid, Noman, Munir, Rubina, Chaudhry, Faryal, Imran, Aqeel, Zaib, Sumera, Muzaffar, Ayesha, Iqbal, Jamshed

Journal:

Bioorganic Chemistry

Year:

2020

File:

PDF, 2.17 MB

2020

71

ent-Pimarane diterpenoids from Siegesbeckia glabrescens with anti-inflammatory activity

Gao, XiaoXu, Rong, ZiJian, Long, GuoQing, Hu, GaoSheng, Yan, Ting, Li, Na, Jia, JingMing, Wang, AnHua

Journal:

Bioorganic Chemistry

Year:

2020

File:

PDF, 335 KB

2020

72

On-cell saturation transfer difference NMR study of Bombesin binding to GRP receptor

Palmioli, Alessandro, Ceresa, Cecilia, Tripodi, Farida, La Ferla, Barbara, Nicolini, Gabriella, Airoldi, Cristina

Journal:

Bioorganic Chemistry

Year:

2020

File:

PDF, 842 KB

2020

73

Anti-cancer potential of sophoridine and its derivatives: Recent progress and future perspectives

ur Rashid, Haroon, Rasool, Shagufta, Ali, Yousaf, Khan, Kamin, Martines, Marco Antonio Utrera

Journal:

Bioorganic Chemistry

Year:

2020

File:

PDF, 4.77 MB

2020

74

New tranylcypromine derivatives containing sulfonamide motif as potent LSD1 inhibitors to target acute myeloid leukemia: Design, synthesis and biological evaluation

Liang, Liyun, Wang, Haiwen, Du, Yongliang, Luo, Bingling, Meng, Ning, Cen, Meifeng, Huang, Peng, Ganesan, A., Wen, Shijun

Journal:

Bioorganic Chemistry

Year:

2020

File:

PDF, 4.01 MB

2020

75

Design, synthesis and biological evaluation of novel 5-((substituted quinolin-3-yl/1-naphthyl) methylene)-3-substituted imidazolidin-2,4-dione as HIV-1 fusion inhibitors

Ibrahim, Tarek S., Bokhtia, Riham M., AL-Mahmoudy, Amany M.M., Taher, Ehab S., AlAwadh, Mohammed A., Elagawany, Mohamed, Abdel-Aal, Eatedal H., Panda, Siva, Gouda, Ahmed M., Asfour, Hany Z., Alhakamy,

Journal:

Bioorganic Chemistry

Year:

2020

File:

PDF, 3.59 MB

2020

76

1,4,5,6,7,8-Hexahydroquinolines and 5,6,7,8-tetrahydronaphthalenes: A new class of antitumor agents targeting the colchicine binding site of tubulin

Shaheen, Mennatallah A., El-Emam, Ali A., El-Gohary, Nadia S.

Journal:

Bioorganic Chemistry

Year:

2020

File:

PDF, 3.73 MB

2020

77

Compounds from the fruits of mangrove Sonneratia apetala: Isolation, molecular docking and antiaging effects using a Caenorhabditis elegans model

Yi, Xiangxi, Jiang, Shu, Qin, Mei, Liu, Kai, Cao, Pei, Chen, Shimin, Deng, Jiagang, Gao, Chenghai

Journal:

Bioorganic Chemistry

Year:

2020

File:

PDF, 2.45 MB

2020

78

One-pot cascade synthesis of benzopyrans and dihydropyrano[c]chromenes catalyzed by lipase TLIM

Fu, Yajie, Lu, Zeping, Ma, Xiaolong, Fang, Ke, He, Xinyi, Xu, Huajin, Hu, Yi

Journal:

Bioorganic Chemistry

Year:

2020

File:

PDF, 452 KB

2020

79

Chromatograpic resolution of phenylethanolic-azole racemic compounds highlighted stereoselective inhibition of heme oxygenase-1 by (R)-enantiomers

Floresta, Giuseppe, Carotti, Andrea, Ianni, Federica, Sorrenti, Valeria, Intagliata, Sebastiano, Rescifina, Antonio, Salerno, Loredana, Di Michele, Alessandro, Sardella, Roccaldo, PittalÃ , Valeria

Journal:

Bioorganic Chemistry

Year:

2020

File:

PDF, 1.16 MB

2020

80

Editorial Board

Journal:

Bioorganic Chemistry

Year:

2020

File:

PDF, 47 KB

2020

81

A stilbene dimer and flavonoids from the aerial parts of Chromolaena odorata with proprotein convertase subtilisin/kexin type 9 expression inhibitory activity

Pel, Pisey, Chae, Hee-Sung, Nhoek, Piseth, Kim, Young-Mi, Khiev, Piseth, Kim, Geum Jin, Nam, Joo-Won, Choi, Hyukjae, Choi, Young Hee, Chin, Young-Won

Journal:

Bioorganic Chemistry

Year:

2020

File:

PDF, 1.74 MB

2020

82

Synthesis, anti-convulsant activity and molecular docking study of novel thiazole pyridazinone hybrid analogues

Siddiqui, Aness Ahmad, Partap, Sangh, Khisal, Subuhi, Yar, Mohammad Shahar, Mishra, Ravinesh

Journal:

Bioorganic Chemistry

Year:

2020

File:

PDF, 4.93 MB

2020

83

Identification of rapid access to polycyclic systems via a base-catalyzed cascade cyclization reaction and their biological evaluation

Ling, Taotao, Hadi, Victor, Bollinger, John, Rivas, Fatima

Journal:

Bioorganic Chemistry

Year:

2020

File:

PDF, 1.39 MB

2020

84

Corrigendum to âEngineered Î²-hairpin scaffolds from human prion protein regions: Structural and functional investigations of aggregatesâ [Bioorg. Chem. 96 (2020) 103594]

Di Natale, Concetta, La Manna, Sara, Avitabile, Concetta, Florio, Daniele, Morelli, Giancarlo, Netti, Paolo Antonio, Marasco, Daniela

Journal:

Bioorganic Chemistry

Year:

2020

File:

PDF, 349 KB

2020

85

Issue TOC

Journal:

Bioorganic Chemistry

Year:

2020

File:

PDF, 5.03 MB

2020

86

Novel diindoloazepinone derivatives as DNA minor groove binding agents with selective topoisomerase I inhibition: Design, synthesis, biological evaluation and docking studies

Kadagathur, Manasa, Devi, G. Parimala, Grewal, Preeti, Sigalapalli, Dilep Kumar, Makhal, Priyanka N., Banerjee, Uttam Chand, Bathini, Nagendra Babu, Tangellamudi, Neelima D.

Journal:

Bioorganic Chemistry

Year:

2020

File:

PDF, 7.85 MB

2020