Volume 76; Issue 1

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British Journal of Clinical Pharmacology
Volume 76; Issue 1

British Journal of Clinical Pharmacology

Volume 76; Issue 1

1

Safety, tolerability, pharmacokinetics and pharmacodynamics of losmapimod following a single intravenous or oral dose in healthy volunteers

Barbour, April M., Sarov-Blat, Lea, Cai, Gengqian, Fossler, Michael J., Sprecher, Dennis L., Graggaber, Johann, McGeoch, Adam T., Maison, Jo, Cheriyan, Joseph

Journal:

British Journal of Clinical Pharmacology

Year:

2013

Language:

english

File:

PDF, 528 KB

english, 2013

2

Pharmacokinetics of fostamatinib, a spleen tyrosine kinase (SYK) inhibitor, in healthy human subjects following single and multiple oral dosing in three phase I studies

Baluom, Muhammad, Grossbard, Elliott B., Mant, Tim, Lau, David T. W.

Journal:

British Journal of Clinical Pharmacology

Year:

2013

Language:

english

File:

PDF, 461 KB

english, 2013

3

Effect of hepatic impairment on the pharmacokinetics and pharmacodynamics of a single dose of rivaroxaban, an oral, direct Factor Xa inhibitor

Kubitza, Dagmar, Roth, Angelika, Becka, Michael, Alatrach, Abir, Halabi, Atef, Hinrichsen, Holger, Mueck, Wolfgang

Journal:

British Journal of Clinical Pharmacology

Year:

2013

Language:

english

File:

PDF, 435 KB

english, 2013

4

Drug induced QT prolongation: the measurement and assessment of the QT interval in clinical practice

Isbister, Geoffrey K., Page, Colin B.

Journal:

British Journal of Clinical Pharmacology

Year:

2013

Language:

english

File:

PDF, 1.14 MB

english, 2013

5

Future of the European Union regulatory network in the context of the uptake of new medicines

Hoebert, Joëlle M., Irs, Alar, Mantel-Teeuwisse, Aukje K., Leufkens, Hubert G. M.

Journal:

British Journal of Clinical Pharmacology

Year:

2013

Language:

english

File:

PDF, 492 KB

english, 2013

6

Randomized controlled trials of antibiotics for neonatal infections: a systematic review

Kaguelidou, Florentia, Turner, Mark A., Choonara, Imti, van Anker, John, Manzoni, Paolo, Alberti, Corinne, Langhendries, Jean-Paul, Jacqz-Aigrain, Evelyne

Journal:

British Journal of Clinical Pharmacology

Year:

2013

Language:

english

File:

PDF, 800 KB

english, 2013

7

Optimizing drug development of anti-cancer drugs in children using modelling and simulation

van Hasselt, Johan G.C., van Eijkelenburg, Natasha K.A., Beijnen, Jos H., Schellens, Jan H.M., Huitema, Alwin D.R.

Journal:

British Journal of Clinical Pharmacology

Year:

2013

Language:

english

File:

PDF, 1.59 MB

english, 2013

8

Issue Information

Journal:

British Journal of Clinical Pharmacology

Year:

2013

Language:

english

File:

PDF, 341 KB

english, 2013

9

Detection of medication-related problems in hospital practice: a review

Manias, Elizabeth

Journal:

British Journal of Clinical Pharmacology

Year:

2013

Language:

english

File:

PDF, 966 KB

english, 2013

10

Surinabant, a selective cannabinoid receptor type 1 antagonist, inhibits Δ 9 -tetrahydrocannabinol-induced central nervous system and heart rate effects in humans

Klumpers, Linda E., Roy, Christine, Ferron, Geraldine, Turpault, Sandrine, Poitiers, Franck, Pinquier, Jean-Louis, van Hasselt, Johan G. C., Zuurman, Lineke, Erwich, Frank A. S., van Gerven, Joop M. A

Journal:

British Journal of Clinical Pharmacology

Year:

2013

Language:

english

File:

PDF, 1.11 MB

english, 2013

11

AT 1 mutations and risk of atrial fibrillation based on genotypes from 71 000 individuals from the general population

Marott, Sarah C. W., Nordestgaard, Børge G., Jensen, Gorm B., Tybjaerg-Hansen, Anne, Benn, Marianne

Journal:

British Journal of Clinical Pharmacology

Year:

2013

Language:

english

File:

PDF, 1.15 MB

english, 2013

12

A semi-mechanistic absorption model to evaluate drug-drug interaction with dabigatran: application with clarithromycin

Delavenne, Xavier, Ollier, Edouard, Basset, Thierry, Bertoletti, Laurent, Accassat, Sandrine, Garcin, Arnauld, Laporte, Silvy, Zufferey, Paul, Mismetti, Patrick

Journal:

British Journal of Clinical Pharmacology

Year:

2013

Language:

english

File:

PDF, 811 KB

english, 2013

13

Evaluation of nevirapine dosing recommendations in HIV-infected children

Foissac, Frantz, Bouazza, Naïm, Frange, Pierre, Blanche, Stéphane, Faye, Albert, Lachassinne, Eric, Dollfus, Catherine, Hirt, Déborah, Benaboud, Sihem, Treluyer, Jean-Marc, Urien, Saïk

Journal:

British Journal of Clinical Pharmacology

Year:

2013

Language:

english

File:

PDF, 1017 KB

english, 2013

14

Thiopurine methyltransferase genotype-phenotype discordance and thiopurine active metabolite formation in childhood acute lymphoblastic leukaemia

Lennard, Lynne, Cartwright, Cher Suzanne, Wade, Rachel, Richards, Susan M., Vora, Ajay

Journal:

British Journal of Clinical Pharmacology

Year:

2013

Language:

english

File:

PDF, 1.38 MB

english, 2013

15

Antiplatelet therapy in ACS and A-FibAdvances in Cardiology, vol. 47, Antiplatelet therapy in ACS and A-Fib. Editor(s) edited by V.L.Serebruany and D.Atar. Published by Karger AG, Basel. 2012. 170 pp, price $167.00. ISBN 978-3-318-02168-4

Journal:

British Journal of Clinical Pharmacology

Year:

2013

Language:

english

File:

PDF, 348 KB

english, 2013

16

Duration of vancomycin treatment for coagulase-negative Staphylococcus sepsis in very low birth weight infants

Linder, Nehama, Lubin, Daniel, Hernandez, Adriana, Amit, Limor, Ashkenazi, Shai

Journal:

British Journal of Clinical Pharmacology

Year:

2013

Language:

english

File:

PDF, 634 KB

english, 2013

17

Validation of suicide and self-harm records in the Clinical Practice Research Datalink

Thomas, Kyla H., Davies, Neil, Metcalfe, Chris, Windmeijer, Frank, Martin, Richard M., Gunnell, David

Journal:

British Journal of Clinical Pharmacology

Year:

2013

Language:

english

File:

PDF, 1.81 MB

english, 2013