Volume 161; Issue 6

British Journal of Pharmacology

Volume 161; Issue 6

1

Ligand binding assays at equilibrium: validation and interpretation

Edward C. Hulme, Mike A. Trevethick

Journal:

British Journal of Pharmacology

Year:

2010

Language:

english

File:

PDF, 1.14 MB

english, 2010

2

Histamine modulates γδ-T lymphocyte migration and cytotoxicity, via Gi and Gs protein-coupled signalling pathways

K Truta-Feles, M Lagadari, K Lehmann, L Berod, S Cubillos, S Piehler, Y Herouy, D Barz, T Kamradt, AA Maghazachi, J Norgauer

Journal:

British Journal of Pharmacology

Year:

2010

Language:

english

File:

PDF, 1.39 MB

english, 2010

3

α1-Adrenoceptor-mediated contraction of rat aorta is partly mediated via transactivation of the epidermal growth factor receptor

N Ulu, H Gurdal, SW Landheer, M Duin, MO Guc, H Buikema, RH Henning

Journal:

British Journal of Pharmacology

Year:

2010

Language:

english

File:

PDF, 1.13 MB

english, 2010

4

Elusive equilibrium: the challenge of interpreting receptor pharmacology using calcium assays

Steven J Charlton, Georges Vauquelin

Journal:

British Journal of Pharmacology

Year:

2010

Language:

english

File:

PDF, 1.46 MB

english, 2010

5

Matching models to data: a receptor pharmacologist's guide

David A Hall, Christopher J Langmead

Journal:

British Journal of Pharmacology

Year:

2010

Language:

english

File:

PDF, 1003 KB

english, 2010

6

Estimation of the dissociation rate of unlabelled ligand–receptor complexes by a ‘two-step’ competition binding approach

A Packeu, M Wennerberg, A Balendran, G Vauquelin

Journal:

British Journal of Pharmacology

Year:

2010

Language:

english

File:

PDF, 3.30 MB

english, 2010

7

Suppression of antibody-mediated arthritis in mice by Fab fragments of the mediating antibodies

S Yoshino, M Sasahara, Pilaiwanwadee Hutamekalin, K Yamaki, N Mizutani, H Kuramoto

Journal:

British Journal of Pharmacology

Year:

2010

Language:

english

File:

PDF, 1.54 MB

english, 2010

8

Role of mitochondria in contraction and pacemaking in the mouse uterus

FS Gravina, HC Parkington, KP Kerr, RB De Oliveira, P Jobling, HA Coleman, SL Sandow, MM Davies, MS Imtiaz, DF Van Helden

Journal:

British Journal of Pharmacology

Year:

2010

Language:

english

File:

PDF, 2.35 MB

english, 2010

9

Use of the GTPγS ([35S]GTPγS and Eu-GTPγS) binding assay for analysis of ligand potency and efficacy at G protein-coupled receptors

Philip G. Strange

Journal:

British Journal of Pharmacology

Year:

2010

Language:

english

File:

PDF, 647 KB

english, 2010

10

Identification of a novel snake peptide toxin displaying high affinity and antagonist behaviour for the α2-adrenoceptors

Céline Rouget, Loïc Quinton, Arhamatoulaye Maïga, Céline Gales, Geoffrey Masuyer, Christian Malosse, Julia Chamot-Rooke, Robert Thai, Gilles Mourier, Edwin De Pauw, Nicolas Gilles, Denis Servent

Journal:

British Journal of Pharmacology

Year:

2010

Language:

english

File:

PDF, 1.68 MB

english, 2010

11

Activation of µ-opioid receptors and block of KIR3 potassium channels and NMDA receptor conductance by l- and d-methadone in rat locus coeruleus

Aya Matsui, John T. Williams

Journal:

British Journal of Pharmacology

Year:

2010

Language:

english

File:

PDF, 1.29 MB

english, 2010

12

The inhibitor of 20-HETE synthesis, TS-011, improves cerebral microcirculatory autoregulation impaired by middle cerebral artery occlusion in mice

Toshiyuki Marumo, Kei Eto, Hiroaki Wake, Tomohiro Omura, Junichi Nabekura

Journal:

British Journal of Pharmacology

Year:

2010

Language:

english

File:

PDF, 1.74 MB

english, 2010

13

Dual bronchodilatory and pulmonary anti-inflammatory activity of RO5024118, a novel agonist at vasoactive intestinal peptide VPAC2 receptors

SA Tannu, LM Renzetti, N Tare, JD Ventre, D Lavelle, TA Lin, A Morschauser, J Paciorek, DR Bolin, H Michel, L Singer, M Hargaden, ID Knowles, P Gardiner, M Cazzola, L Calzetta, MG Matera, A. Hicks

Journal:

British Journal of Pharmacology

Year:

2010

Language:

english

File:

PDF, 3.09 MB

english, 2010

14

Ranolazine selectively blocks persistent current evoked by epilepsy-associated NaV1.1 mutations

Kristopher M Kahlig, Irene Lepist, Kwan Leung, Sridharan Rajamani, Alfred L George

Journal:

British Journal of Pharmacology

Year:

2010

Language:

english

File:

PDF, 1006 KB

english, 2010

15

Effect of experimental hyperlipidaemia on the electrocardiographic effects of repeated doses of halofantrine in rats

Jigar P Patel, Dion R Brocks

Journal:

British Journal of Pharmacology

Year:

2010

Language:

english

File:

PDF, 1.23 MB

english, 2010

16

Analysis of the actions of the novel dopamine receptor-directed compounds (S)-OSU6162 and ACR16 at the D2 dopamine receptor

Elodie Kara, Hong Lin, Kjell Svensson, Anette M Johansson, Philip G Strange

Journal:

British Journal of Pharmacology

Year:

2010

Language:

english

File:

PDF, 598 KB

english, 2010

17

Reflections on drug research

Journal:

British Journal of Pharmacology

Year:

2010

Language:

english

File:

PDF, 668 KB

english, 2010

18

BJP issue on drug discovery

Steven J. Charlton, Richard A. Bond

Journal:

British Journal of Pharmacology

Year:

2010

Language:

english

File:

PDF, 180 KB

english, 2010

19

Foreword to Reflections on Drug Research by Sir James Black

Rona Mackie Black

Journal:

British Journal of Pharmacology

Year:

2010

Language:

english

File:

PDF, 133 KB

english, 2010

20

Reviewer comments on Reflections on drug research by Sir James Black

Journal:

British Journal of Pharmacology

Year:

2010

Language:

english

File:

PDF, 136 KB

english, 2010

21

Reviewer comments on Reflections on drug research by Sir James Black

Journal:

British Journal of Pharmacology

Year:

2010

Language:

english

File:

PDF, 140 KB

english, 2010

22

Mandarin Translations

Journal:

British Journal of Pharmacology

Year:

2010

Language:

english

File:

PDF, 6.61 MB

english, 2010

23

Insights into GPCR pharmacology from the measurement of changes in intracellular cyclic AMP; advantages and pitfalls of differing methodologies

Stephen J Hill, Christine Williams, Lauren T May

Journal:

British Journal of Pharmacology

Year:

2010

Language:

english

File:

PDF, 616 KB

english, 2010

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