Volume 166; Issue 3

British Journal of Pharmacology

Volume 166; Issue 3

1

Pharmacological characterization of a small-molecule agonist for the chemokine receptor CXCR3

DJ Scholten, M Canals, M Wijtmans, S de Munnik, P Nguyen, D Verzijl, IJP de Esch, HF Vischer, MJ Smit, R Leurs

Journal:

British Journal of Pharmacology

Year:

2012

Language:

english

File:

PDF, 1.90 MB

english, 2012

2

Small molecule chemokine mimetics suggest a molecular basis for the observation that CXCL10 and CXCL11 are allosteric ligands of CXCR3

Belinda Nedjai, Hubert Li, Ilana L Stroke, Emma L Wise, Maria L Webb, J Robert Merritt, Ian Henderson, Anthony E Klon, Andrew G Cole, Richard Horuk, Nagarajan Vaidehi, James E Pease

Journal:

British Journal of Pharmacology

Year:

2012

Language:

english

File:

PDF, 2.79 MB

english, 2012

3

Direct pharmacological monitoring of the developmental switch in NMDA receptor subunit composition using TCN 213, a GluN2A-selective, glycine-dependent antagonist

S McKay, NH Griffiths, PA Butters, EB Thubron, GE Hardingham, DJA Wyllie

Journal:

British Journal of Pharmacology

Year:

2012

Language:

english

File:

PDF, 2.22 MB

english, 2012

4

The yin and yang of chemokine receptor activation

Journal:

British Journal of Pharmacology

Year:

2012

Language:

english

File:

PDF, 159 KB

english, 2012

5

Dronedarone prevents microcirculatory abnormalities in the left ventricle during atrial tachypacing in pigs

A Bukowska, M Hammwöhner, A Sixdorf, L Schild, I Wiswedel, F-W Röhl, C Wolke, U Lendeckel, C Aderkast, S Bochmann, RK Chilukoti, J Mostertz, P Bramlage, A Goette

Journal:

British Journal of Pharmacology

Year:

2012

Language:

english

File:

PDF, 1.32 MB

english, 2012

6

Differential inhibition of tumour cell-induced platelet aggregation by the nicotinate aspirin prodrug (ST0702) and aspirin

Carlos Medina, Shona Harmon, Iwona Inkielewicz, Maria Jose Santos-Martinez, Michael Jones, Paula Cantwell, Despina Bazou, Mark Ledwidge, Marek W. Radomski, John F. Gilmer

Journal:

British Journal of Pharmacology

Year:

2012

Language:

english

File:

PDF, 2.46 MB

english, 2012

7

Pharmacological activity of a Bv8 analogue modified in position 24

R Lattanzi, P Sacerdote, S Franchi, M Canestrelli, R Miele, D Barra, S Visentin, C DeNuccio, F Porreca, M De Felice, F Guida, L Luongo, V de Novellis, S Maione, L Negri

Journal:

British Journal of Pharmacology

Year:

2012

Language:

english

File:

PDF, 1.22 MB

english, 2012

8

Phospho-ibuprofen (MDC-917) incorporated in nanocarriers: anti-cancer activity in vitro and in vivo

T Nie, CC Wong, N Alston, P Aro, PP Constantinides, B Rigas

Journal:

British Journal of Pharmacology

Year:

2012

Language:

english

File:

PDF, 1.63 MB

english, 2012

9

Subtype selective NMDA receptor antagonists induce recovery of synapses lost following exposure to HIV-1 Tat

AH Shin, HJ Kim, SA Thayer

Journal:

British Journal of Pharmacology

Year:

2012

Language:

english

File:

PDF, 5.96 MB

english, 2012

10

The GPCR OGR1 (GPR68) mediates diverse signalling and contraction of airway smooth muscle in response to small reductions in extracellular pH

H Saxena, DA Deshpande, BC Tiegs, H Yan, RJ Battafarano, WM Burrows, G Damera, RA Panettieri, TD DuBose Jr, SS An, RB Penn

Journal:

British Journal of Pharmacology

Year:

2012

Language:

english

File:

PDF, 1.39 MB

english, 2012

11

Concordance of preclinical and clinical pharmacology and toxicology of therapeutic monoclonal antibodies and fusion proteins: cell surface targets

Peter J Bugelski, Pauline L Martin

Journal:

British Journal of Pharmacology

Year:

2012

Language:

english

File:

PDF, 2.15 MB

english, 2012

12

Concordance of preclinical and clinical pharmacology and toxicology of monoclonal antibodies and fusion proteins: soluble targets

Pauline L Martin, Peter J Bugelski

Journal:

British Journal of Pharmacology

Year:

2012

Language:

english

File:

PDF, 757 KB

english, 2012

13

Access of inhibitory neurosteroids to the NMDA receptor

Jirina Borovska, Vojtech Vyklicky, Eva Stastna, Vojtech Kapras, Barbora Slavikova, Martin Horak, Hana Chodounska, Ladislav Vyklicky Jr

Journal:

British Journal of Pharmacology

Year:

2012

Language:

english

File:

PDF, 2.21 MB

english, 2012

14

Prostanoid EP1 receptors mediate up-regulation of the orphan nuclear receptor Nurr1 by cAMP-independent activation of protein kinase A, CREB and NF-κB

R Ji, CM Sanchez, CL Chou, XB Chen, DF Woodward, JW Regan

Journal:

British Journal of Pharmacology

Year:

2012

Language:

english

File:

PDF, 1.77 MB

english, 2012

15

Activation of NK1 receptors in the locus coeruleus induces analgesia through noradrenergic-mediated descending inhibition in a rat model of neuropathic pain

Y Muto, A Sakai, A Sakamoto, H Suzuki

Journal:

British Journal of Pharmacology

Year:

2012

Language:

english

File:

PDF, 1.34 MB

english, 2012

16

Thiazolidinedione-dependent activation of sphingosine kinase 1 causes an anti-fibrotic effect in renal mesangial cells

A Koch, A Völzke, C Wünsche, D Meyer zu Heringdorf, A Huwiler, J Pfeilschifter

Journal:

British Journal of Pharmacology

Year:

2012

Language:

english

File:

PDF, 2.41 MB

english, 2012

17

Drug-like actions of autoantibodies against receptors of the autonomous nervous system and their impact on human heart function

LR Herda, SB Felix, F Boege

Journal:

British Journal of Pharmacology

Year:

2012

Language:

english

File:

PDF, 781 KB

english, 2012

18

Triptolide increases transcript and protein levels of survival motor neurons in human SMA fibroblasts and improves survival in SMA-like mice

Ya-Yun Hsu, Yuh-Jyh Jong, Hsin-Hung Tsai, Yu-Ting Tseng, Li-Mei An, Yi-Ching Lo

Journal:

British Journal of Pharmacology

Year:

2012

Language:

english

File:

PDF, 2.51 MB

english, 2012

19

Inflammatory muscle pain is dependent on the activation of kinin B1 and B2 receptors and intracellular kinase pathways

FC Meotti, R Campos, KABS da Silva, AF Paszcuk, R Costa, JB Calixto

Journal:

British Journal of Pharmacology

Year:

2012

Language:

english

File:

PDF, 1.34 MB

english, 2012

20

Adenosine-5′-triphosphate up-regulates proliferation of human cardiac fibroblasts

Jing-Bo Chen, Wen-Juan Liu, Hui Che, Jie Liu, Hai-Ying Sun, Gui-Rong Li

Journal:

British Journal of Pharmacology

Year:

2012

Language:

english

File:

PDF, 2.01 MB

english, 2012

21

Caffeic acid phenethyl ester protects nigral dopaminergic neurons via dual mechanisms involving haem oxygenase-1 and brain-derived neurotrophic factor

Y Kurauchi, A Hisatsune, Y Isohama, S Mishima, H Katsuki

Journal:

British Journal of Pharmacology

Year:

2012

Language:

english

File:

PDF, 4.81 MB

english, 2012

22

Topical application of disodium isostearyl 2-O-L-ascorbyl phosphate, an amphiphilic ascorbic acid derivative, reduces neuropathic hyperalgesia in rats

Kazumasa Okubo, Hiroki Nakanishi, Maho Matsunami, Hiroharu Shibayama, Atsufumi Kawabata

Journal:

British Journal of Pharmacology

Year:

2012

Language:

english

File:

PDF, 1.64 MB

english, 2012

23

A prolyl oligopeptidase inhibitor, KYP-2047, reduces α-synuclein protein levels and aggregates in cellular and animal models of Parkinson's disease

TT Myöhänen, MJ Hannula, R Van Elzen, M Gerard, P Van Der Veken, JA García-Horsman, V Baekelandt, PT Männistö, AM Lambeir

Journal:

British Journal of Pharmacology

Year:

2012

Language:

english

File:

PDF, 6.59 MB

english, 2012

24

Loss of multidrug and toxin extrusion 1 (MATE1) is associated with metformin-induced lactic acidosis

K Toyama, A Yonezawa, S Masuda, R Osawa, M Hosokawa, S Fujimoto, N Inagaki, K Inui, T Katsura

Journal:

British Journal of Pharmacology

Year:

2012

Language:

english

File:

PDF, 694 KB

english, 2012

25

Inhibition of high glucose-induced inflammatory response and macrophage infiltration by a novel curcumin derivative prevents renal injury in diabetic rats

Yong Pan, Yi Wang, Lu Cai, Yuepiao Cai, Jie Hu, Congcong Yu, Jianling Li, Zhiguo Feng, Shulin Yang, Xiaokun Li, Guang Liang

Journal:

British Journal of Pharmacology

Year:

2012

Language:

english

File:

PDF, 5.51 MB

english, 2012

26

The natural polyamines spermidine and spermine prevent bone loss through preferential disruption of osteoclastic activation in ovariectomized mice

Tomomi Yamamoto, Eiichi Hinoi, Hiroyuki Fujita, Takashi Iezaki, Yoshifumi Takahata, Misa Takamori, Yukio Yoneda

Journal:

British Journal of Pharmacology

Year:

2012

Language:

english

File:

PDF, 2.69 MB

english, 2012

27

A guide to picking the most selective kinase inhibitor tool compounds for pharmacological validation of drug targets

Joost CM Uitdehaag, Folkert Verkaar, Husam Alwan, Jos de Man, Rogier C Buijsman, Guido JR Zaman

Journal:

British Journal of Pharmacology

Year:

2012

Language:

english

File:

PDF, 1.60 MB

english, 2012

28

Analysis of variance: variably complex

Gordon B Drummond, Sarah L Vowler

Journal:

British Journal of Pharmacology

Year:

2012

Language:

english

File:

PDF, 363 KB

english, 2012

29

The use of animal models in diabetes research

Journal:

British Journal of Pharmacology

Year:

2012

Language:

english

File:

PDF, 790 KB

english, 2012

30

Corrigendum

Journal:

British Journal of Pharmacology

Year:

2012

File:

PDF, 203 KB

2012

31

Mandarin Translations

Journal:

British Journal of Pharmacology

Year:

2012

Language:

english

File:

PDF, 11.03 MB

english, 2012