Volume 68; Issue 2

Cancer Chemotherapy and Pharmacology

Volume 68; Issue 2

1

Anticancer effect of (E)-2-hydroxy-3′,4,5′-trimethoxystilbene on breast cancer cells by mitochondrial depolarization

Yee Soo Chae, Jong Gwang Kim, Hyun Jun Jung, Jung Dug Yang, Jin Hyang Jung, Sarah E. Aiyar, Sanghee Kim, Hoyong Park

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2011

Language:

english

File:

PDF, 475 KB

english, 2011

2

A prospective phase II study of 2-methoxyestradiol administered in combination with bevacizumab in patients with metastatic carcinoid tumors

Matthew H. Kulke, Jennifer A. Chan, Jeffrey A. Meyerhardt, Andrew X. Zhu, Thomas A. Abrams, Lawrence S. Blaszkowsky, Eileen Regan, Carolyn Sidor, Charles S. Fuchs

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2011

Language:

english

File:

PDF, 230 KB

english, 2011

3

Nilotinib in patients with GIST who failed imatinib and sunitinib: importance of prior surgery on drug bioavailability

Kyu-pyo Kim, Min-Hee Ryu, Changhoon Yoo, Baek-Yeol Ryoo, Dae Ro Choi, Heung Moon Chang, Jae-Lyun Lee, Mo Youl Beck, Tae Won Kim, Yoon-Koo Kang

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2011

Language:

english

File:

PDF, 254 KB

english, 2011

4

Is there any impact of plasma M30 and M65 levels on progression-free survival of patients with advanced gastric cancer?

Ahmet Bilici, Bala Basak Oven Ustaalioglu, Serif Ercan, Asuman Orcun, Mesut Seker, Taflan Salepci, Mahmut Gumus

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2011

Language:

english

File:

PDF, 233 KB

english, 2011

5

Phase II trial of the ribonucleotide reductase inhibitor 3-aminopyridine-2-carboxaldehydethiosemicarbazone plus gemcitabine in patients with advanced biliary tract cancer

Allyson J. Ocean, Paul Christos, Joseph A. Sparano, Dan Matulich, Andreas Kaubish, Abby Siegel, Max Sung, Maureen M. Ward, Nancy Hamel, Igor Espinoza-Delgado, Yun Yen, Maureen E. Lane

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2011

Language:

english

File:

PDF, 273 KB

english, 2011

6

Clinical benefit of early phase clinical trial participation for advanced sarcoma patients

Robin L. Jones, David Olmos, Khin Thway, Cyril Fisher, Nina Tunariu, Sophie Postel-Vinay, Michelle Scurr, Johann de Bono, Stan B. Kaye, Ian R. Judson

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2011

Language:

english

File:

PDF, 400 KB

english, 2011

7

UGT1A11/28and1/6genotypes have no effects on the efficacy and toxicity of FOLFIRI in Japanese patients with advanced colorectal cancer

Yu Sunakawa, Wataru Ichikawa, Ken-ichi Fujita, Fumio Nagashima, Hiroo Ishida, Keishi Yamashita, Keiko Mizuno, Keisuke Miwa, Kaori Kawara, Yuko Akiyama, Kazuhiro Araki, Wataru Yamamoto, Toshimichi Miya

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2011

Language:

english

File:

PDF, 176 KB

english, 2011

8

The PI-3 kinase-Akt-MDM2-survivin signaling axis in high-risk neuroblastoma: a target for PI-3 kinase inhibitor intervention

Susan K. Peirce, Harry W. Findley, Chengyu Prince, Anindya Dasgupta, Todd Cooper, Donald L. Durden

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2011

Language:

english

File:

PDF, 789 KB

english, 2011

9

Meta-analysis of neutropenia or leukopenia as a prognostic factor in patients with malignant disease undergoing chemotherapy

Kohei Shitara, Keitaro Matsuo, Isao Oze, Ayako Mizota, Chihiro Kondo, Motoo Nomura, Tomoya Yokota, Daisuke Takahari, Takashi Ura, Kei Muro

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2011

Language:

english

File:

PDF, 352 KB

english, 2011

10

Experiment on enhancing antitumor effect of intravenous epirubicin hydrochloride by acoustic cavitation in situ combined with phospholipid-based microbubbles

Cui-Tao Lu, Ying-Zheng Zhao, Yan Wu, Xin-Qiao Tian, Wen-Feng Li, Pin-Tong Huang, Xiao-Kun Li, Chang-Zheng Sun, Lu Zhang

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2011

Language:

english

File:

PDF, 418 KB

english, 2011

11

Conjugation of chlorinp6to histamine enhances its cellular uptake and phototoxicity in oral cancer cells

Arpana Parihar, Alok Dube, P. K. Gupta

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2011

Language:

english

File:

PDF, 720 KB

english, 2011

12

Phase I dose-escalating study of biweekly fixed-dose rate gemcitabine plus pemetrexed in patients with advanced solid tumors

Yuan Yuan, Deirdre J. Cohen, Erica Love, Michelle Yaw, Benjamin Levinson, Steven J. Nicol, Howard S. Hochster

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2011

Language:

english

File:

PDF, 289 KB

english, 2011

13

Second platinum therapy in patients with uterine cervical cancer previously treated with platinum chemotherapy

Maki Tanioka, Noriyuki Katsumata, Kan Yonemori, Tsutomu Kouno, Chikako Shimizu, Kenji Tamura, Masashi Ando, Yasuhiro Fujiwara

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2011

Language:

english

File:

PDF, 173 KB

english, 2011

14

The histone deacetylase inhibitor PXD101 increases the efficacy of irinotecan in in vitro and in vivo colon cancer models

Young-Soon Na, Kyung-Ah Jung, Seung-Mi Kim, Yong Sang Hong, Min-Hee Ryu, Se Jin Jang, Dae Hyuk Moon, Dong-Hyung Cho, Jin Cheon Kim, Jung Shin Lee, Tae Won Kim

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2011

Language:

english

File:

PDF, 874 KB

english, 2011

15

Clinical impact of K-rasmutation in colorectal cancer patients treated with adjuvant FOLFOX

Myung Hee Chang, In Kyu Lee, Yoon Si, Kyu Sang Lee, In-Sook Woo, Jae Ho Byun

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2011

Language:

english

File:

PDF, 330 KB

english, 2011

16

Lack of in vivo cross-resistance with 4′-thio-ara-C against drug-resistant murine P388 and L1210 leukemias

William R. Waud, Karen S. Gilbert, John A. Secrist

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2011

Language:

english

File:

PDF, 177 KB

english, 2011

17

The uptake of paclitaxel and docetaxel into ex vivo porcine bladder tissue from polymeric micelle formulations

Antonia Tsallas, John Jackson, Helen Burt

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2011

Language:

english

File:

PDF, 604 KB

english, 2011

18

Antitumor agent PX-12 inhibits HIF-1α protein levels through an Nrf2/PMF-1-mediated increase in spermidine/spermine acetyl transferase

Yon Hui Kim, Amy Coon, Amanda F. Baker, Garth Powis

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2011

Language:

english

File:

PDF, 531 KB

english, 2011

19

Antitumor effects of (S)-HDAC42, a phenylbutyrate-derived histone deacetylase inhibitor, in multiple myeloma cells

Li-Yuan Bai, Hany A. Omar, Chang-Fang Chiu, Zeng-Pang Chi, Jing-Lan Hu, Jing-Ru Weng

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2011

Language:

english

File:

PDF, 728 KB

english, 2011

20

Prediction of human pharmacokinetics and tissue distribution of apicidin, a potent histone deacetylase inhibitor, by physiologically based pharmacokinetic modeling

Beom Soo Shin, Jürgen B. Bulitta, Joseph P. Balthasar, Minki Kim, Yohan Choi, Sun Dong Yoo

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2011

Language:

english

File:

PDF, 446 KB

english, 2011

21

The therapeutic efficacy of S-1 against orthotopically implanted human pleural mesothelioma cells in severe combined immunodeficient mice

Trung The Van, Masaki Hanibuchi, Soji Kakiuchi, Seidai Sato, Takuya Kuramoto, Hisatsugu Goto, Atsushi Mitsuhashi, Yasuhiko Nishioka, Shin-ichi Akiyama, Saburo Sone

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2011

Language:

english

File:

PDF, 475 KB

english, 2011

22

Cytotoxic responses to N-(4-hydroxyphenyl)retinamide in human pancreatic cancer cells

Maria C. Messner, Myles C. Cabot

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2011

Language:

english

File:

PDF, 865 KB

english, 2011

23

Improved antiangiogenic and antitumour activity of the combination of the natural flavonoid fisetin and cyclophosphamide in Lewis lung carcinoma-bearing mice

Yasmine S. Touil, Johanne Seguin, Daniel Scherman, Guy G. Chabot

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2011

Language:

english

File:

PDF, 726 KB

english, 2011

24

Phase I study of LY2181308, an antisense oligonucleotide against survivin, in patients with advanced solid tumors

M. Tanioka, H. Nokihara, N. Yamamoto, Y. Yamada, K. Yamada, Y. Goto, T. Fujimoto, R. Sekiguchi, K. Uenaka, S. Callies, T. Tamura

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2011

Language:

english

File:

PDF, 375 KB

english, 2011

25

A dose-escalation study of pemetrexed and docetaxel in non-small-cell lung cancer

Athanasios Kotsakis, Sophia Agelaki, Nikolaos Vardakis, George Stathopoulos, Lambros Vamvakas, Antonia Kalykaki, Nikolaos Kentepozidis, Emmanouel Kontopodis, Georgia Sfakiotaki, Dimitris Mavroudis, Va

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2011

Language:

english

File:

PDF, 184 KB

english, 2011

26

Phase 1/pharmacology study of intraperitoneal topotecan alone and with cisplatin: potential for consolidation in ovarian cancer

Eleni Andreopoulou, Thomas Chen, Leonard Liebes, John Curtin, Stephanie Blank, Robert Wallach, Howard Hochster, Franco Muggia

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2011

Language:

english

File:

PDF, 291 KB

english, 2011

27

Preclinical pharmacokinetics, metabolism, and toxicity of azurin-p28 (NSC745104) a peptide inhibitor of p53 ubiquitination

Lee Jia, Gregory S. Gorman, Lori U. Coward, Patricia E. Noker, David McCormick, Thomas L. Horn, J. Brooks Harder, Miguel Muzzio, Bellur Prabhakar, Balaji Ganesh, Tapas K. Das Gupta, Craig W. Beattie

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2011

Language:

english

File:

PDF, 452 KB

english, 2011

28

Safety and pharmacokinetics of intrathecal administration of pemetrexed in rats

Jong-Mu Sun, Mi Hyun Nam, Jae Yong Chung, Bohee Im, Soo-Youn Lee, Youn-Lim Suh, Jin Seok Ahn, Keunchil Park, Myung-Ju Ahn

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2011

Language:

english

File:

PDF, 530 KB

english, 2011

29

Determination of 5-fluorouracil and dihydrofluorouracil levels by using a liquid chromatography–tandem mass spectrometry method for evaluation of dihydropyrimidine dehydrogenase enzyme activity

Muhittin A. Serdar, Erdim Sertoğlu, Metin Uyanık, Serkan Tapan, Okhan Akın, Murat Cihan

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2011

Language:

english

File:

PDF, 230 KB

english, 2011

30

Pilot study of PD-0325901 in previously treated patients with advanced melanoma, breast cancer, and colon cancer

Peter D. Boasberg, Charles H. Redfern, Gregory A. Daniels, David Bodkin, Chris R. Garrett, Alejandro D. Ricart

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2011

Language:

english

File:

PDF, 251 KB

english, 2011

31

PR-104 plus sorafenib in patients with advanced hepatocellular carcinoma

Ghassan K. Abou-Alfa, Stephan L. Chan, Chia-Chi Lin, E. Gabriela Chiorean, Randall F. Holcombe, Mary F. Mulcahy, William D. Carter, Kashyap Patel, William R. Wilson, Teresa J. Melink, John C. Gutheil,

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2011

Language:

english

File:

PDF, 180 KB

english, 2011

32

Vascular normalization: a real benefit?

Domenico Ribatti

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2011

Language:

english

File:

PDF, 176 KB

english, 2011

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