Volume 78; Issue 1

Cancer Chemotherapy and Pharmacology

Volume 78; Issue 1

1

Pharmacokinetics and pharmacogenetics of Gemcitabine as a mainstay in adult and pediatric oncology: an EORTC-PAMM perspective

Ciccolini, Joseph, Serdjebi, Cindy, Peters, Godefridus J., Giovannetti, Elisa

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2016

Language:

english

File:

PDF, 679 KB

english, 2016

2

Combinational strategies of metformin and chemotherapy in cancers

Zhang, Hui-Hui, Guo, Xiu-Li

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2016

Language:

english

File:

PDF, 921 KB

english, 2016

3

Methotrexate-induced toxicity pharmacogenetics: an umbrella review of systematic reviews and meta-analyses

Campbell, Jared M., Bateman, Emma, Stephenson, Matthew D., Bowen, Joanne M., Keefe, Dorothy M., Peters, Micah D. J.

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2016

Language:

english

File:

PDF, 537 KB

english, 2016

4

A clinical drug–drug interaction study to evaluate the effect of a proton-pump inhibitor, a combined P-glycoprotein/cytochrome 450 enzyme (CYP)3A4 inhibitor, and a CYP2C9 inhibitor on the pharmacokinetics of vismodegib

Malhi, Vikram, Colburn, Dawn, Williams, Sarah J., Hop, Cornelis E. C. A., Dresser, Mark J., Chandra, Priya, Graham, Richard A.

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2016

Language:

english

File:

PDF, 507 KB

english, 2016

5

Phase I safety and pharmacokinetic dose-escalation study of pilaralisib polymorph E, a phosphoinositide 3-kinase inhibitor in tablet formulation, in patients with solid tumors or lymphoma

Bechter, Oliver E., Dumez, Herlinde, Costermans, Jo, Punie, Kevin, Hsu, Karl, Dedieu, Jean-François, Ghuysen, Anne-Frédérique, Francesconi, Elisa, Sharma, Jyoti, Liu, Li, Schöffski, Patrick

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2016

Language:

english

File:

PDF, 468 KB

english, 2016

6

Clinical and pharmacologic evaluation of two dosing schedules of indotecan (LMP400), a novel indenoisoquinoline, in patients with advanced solid tumors

Kummar, Shivaani, Chen, Alice, Gutierrez, Martin, Pfister, Thomas D., Wang, Lihua, Redon, Christophe, Bonner, William M., Yutzy, William, Zhang, Yiping, Kinders, Robert J., Ji, Jiuping, Allen, Deborah

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2016

Language:

english

File:

PDF, 654 KB

english, 2016

7

Everolimus pharmacokinetics and its exposure–toxicity relationship in patients with thyroid cancer

de Wit, D., Schneider, T. C., Moes, D. J. A. R., Roozen, C. F. M., den Hartigh, J., Gelderblom, H., Guchelaar, H. J., van der Hoeven, J. J., Links, T. P., Kapiteijn, E., van Erp, N. P.

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2016

Language:

english

File:

PDF, 652 KB

english, 2016

8

UGT1A1gene polymorphism is associated with toxicity and clinical efficacy of irinotecan-based chemotherapy in patients with advanced colorectal cancer

Xu, Chunlei, Tang, Xushan, Qu, Yanli, Keyoumu, Saifuding, Zhou, Ning, Tang, Yong

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2016

Language:

english

File:

PDF, 487 KB

english, 2016

9

Effects ofCYP3A5polymorphism on the pharmacokinetics of a once-daily modified-release tacrolimus formulation and acute kidney injury in hematopoietic stem cell transplantation

Yamashita, Takaya, Fujishima, Naohito, Miura, Masatomo, Niioka, Takenori, Abumiya, Maiko, Shinohara, Yoshinori, Ubukawa, Kumi, Nara, Miho, Fujishima, Masumi, Kameoka, Yoshihiro, Tagawa, Hiroyuki, Hiro

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2016

Language:

english

File:

PDF, 644 KB

english, 2016

10

Pharmacokinetics and safety of vitamin E δ-tocotrienol after single and multiple doses in healthy subjects with measurement of vitamin E metabolites

Mahipal, Amit, Klapman, Jason, Vignesh, Shivakumar, Yang, Chung S., Neuger, Anthony, Chen, Dung-Tsa, Malafa, Mokenge P.

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2016

Language:

english

File:

PDF, 614 KB

english, 2016

11

Benefit of uridine triacetate (Vistogard) in rescuing severe 5-fluorouracil toxicity in patients with dihydropyrimidine dehydrogenase (DPYD) deficiency

Saif, Muhammad Wasif, Diasio, Robert B.

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2016

Language:

english

File:

PDF, 438 KB

english, 2016

12

Gibberellin derivative GA-13315 sensitizes multidrug-resistant cancer cells by antagonizing ABCB1 while agonizes ABCC1

Mo, Jiao, Kang, Min, Ye, Jun-Xian, Chen, Jing-Bo, Zhang, Hong-bin, Qing, Chen

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2016

Language:

english

File:

PDF, 1.03 MB

english, 2016

13

A phase I study of mTOR inhibitor everolimus in association with cisplatin and radiotherapy for the treatment of locally advanced cervix cancer: PHOENIX I

de Melo, Andréia Cristina, Grazziotin-Reisner, Rachele, Erlich, Felipe, Fontes Dias, Mariane S., Moralez, Giulliana, Carneiro, Michel, Ingles Garces, Álvaro Henrique, Guerra Alves, Flávia Vieira, Nova

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2016

Language:

english

File:

PDF, 534 KB

english, 2016

14

Effects of first-line chemotherapy on natural killer cells in adult T-cell leukemia–lymphoma and peripheral T-cell lymphoma

Ogura, Michinori, Ishida, Takashi, Tsukasaki, Kunihiro, Takahashi, Takeshi, Utsunomiya, Atae

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2016

Language:

english

File:

PDF, 1.66 MB

english, 2016

15

Association between new-onset hypothyroidism and clinical response in patients treated with tyrosine kinase inhibitor therapy in phase I clinical trials

Bilen, Mehmet Asim, Patel, Amy, Hess, Kenneth R., Munoz, Javier, Busaidy, Naifa L., Wheler, Jennifer J., Janku, Filip, Falchook, Gerald S., Hong, David S., Meric-Bernstam, Funda, Habra, Mouhammed Amir

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2016

Language:

english

File:

PDF, 418 KB

english, 2016

16

Pharmacokinetics, safety, and efficacy of lenalidomide plus dexamethasone in patients with multiple myeloma and renal impairment

Bridoux, Frank, Chen, Nianhang, Moreau, Stephane, Arnulf, Bertrand, Moumas, Eric, Abraham, Julie, Desport, Estelle, Jaccard, Arnaud, Fermand, Jean Paul

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2016

Language:

english

File:

PDF, 691 KB

english, 2016

17

Effect of renal function on pemetrexed-induced haematotoxicity

Ando, Yosuke, Hayashi, Takahiro, Ujita, Moeko, Murai, Sumie, Ohta, Hideki, Ito, Kaori, Yamaguchi, Teppei, Funatsu, Minori, Ikeda, Yoshiaki, Imaizumi, Kazuyoshi, Kawada, Kenji, Yasuda, Kimio, Yamada, S

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2016

Language:

english

File:

PDF, 417 KB

english, 2016

18

Chronomodulated oxaliplatin plus Capecitabine (XELOX) as a first line chemotherapy in metastatic colorectal cancer: A Phase II Brunch regimen study

Pilancı, Kezban Nur, Saglam, Sezer, Okyar, Alper, Yucel, Serap, Pala-Kara, Zeliha, Ordu, Cetin, Namal, Esat, Ciftci, Rumeysa, Iner-Koksal, Ulkuhan, Kaytan-Saglam, Esra

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2016

Language:

english

File:

PDF, 470 KB

english, 2016

19

Monte Carlo simulations of the clinical benefits from therapeutic drug monitoring of sunitinib in patients with gastrointestinal stromal tumours

Goulooze, Sebastiaan C., Galettis, Peter, Boddy, Alan V., Martin, Jennifer H.

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2016

Language:

english

File:

PDF, 673 KB

english, 2016

20

Developing more effective, non-neurotoxic, methotrexate-based therapy in infants with brain tumors

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2016

Language:

english

File:

PDF, 349 KB

english, 2016

21

Reply to Prof Ian J. Cohen

Lucchesi, Maurizio, Sardi, Iacopo

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2016

Language:

english

File:

PDF, 342 KB

english, 2016

22

A prospective, multicenter phase I/II study of induction chemotherapy with docetaxel, cisplatin and fluorouracil (DCF) followed by chemoradiotherapy in patients with unresectable locally advanced esophageal carcinoma

Satake, Hironaga, Tahara, Makoto, Mochizuki, Satoshi, Kato, Ken, Hara, Hiroki, Yokota, Tomoya, Kiyota, Naomi, Kii, Takayuki, Chin, Keisho, Zenda, Sadamoto, Kojima, Takashi, Bando, Hideaki, Yamazaki, T

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2016

Language:

english

File:

PDF, 446 KB

english, 2016

23

Atrial natriuretic peptide protects against cisplatin-induced granulocytopenia

Nojiri, Takashi, Hosoda, Hiroshi, Zenitani, Masahiro, Tokudome, Takeshi, Kimura, Toru, Miura, Koichi, Miyazato, Mikiya, Okumura, Meinoshin, Kangawa, Kenji

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2016

Language:

english

File:

PDF, 1.19 MB

english, 2016

24

Accounting for dropout in xenografted tumour efficacy studies: integrated endpoint analysis, reduced bias and better use of animals

Martin, Emma C., Aarons, Leon, Yates, James W. T.

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2016

Language:

english

File:

PDF, 811 KB

english, 2016