Volume 78; Issue 3

Cancer Chemotherapy and Pharmacology

Volume 78; Issue 3

1

Pharmacokinetic variations in cancer patients with liver dysfunction: applications and challenges of pharmacometabolomics

Aboel Dahab, Ali, El-Hag, Dhia, Moutamed, Gamal M., Aboel Dahab, Sarah, Abuknesha, Ramadan, Smith, Norman W.

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2016

Language:

english

File:

PDF, 1.25 MB

english, 2016

2

Therapeutic drug monitoring of 5-fluorouracil

Lee, James J., Beumer, Jan H., Chu, Edward

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2016

Language:

english

File:

PDF, 559 KB

english, 2016

3

A multicenter phase II trial of S-1 combined with bevacizumab after platinum-based chemotherapy in patients with advanced non-squamous non-small cell lung cancer

Yamada, Kazuhiko, Ichiki, Masao, Takahashi, Kazuhisa, Hisamatsu, Yasushi, Takeoka, Hiroaki, Azuma, Koichi, Shukuya, Takehito, Nishikawa, Kazuo, Tokito, Takaaki, Ishii, Hidenobu, Hoshino, Tomoaki

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2016

Language:

english

File:

PDF, 479 KB

english, 2016

4

Phase 1 study to evaluate the effect of the MEK inhibitor trametinib on cardiac repolarization in patients with solid tumours

Patnaik, Amita, Tolcher, Anthony, Papadopoulos, Kyriakos P., Beeram, Murali, Rasco, Drew, Werner, Theresa L., Bauman, John W., Scheuber, Anita, Cox, Donna S., Patel, Bela R., Zhou, YanYan, Hamid, Moha

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2016

Language:

english

File:

PDF, 540 KB

english, 2016

5

A phase II study of the HSP90 inhibitor AUY922 in chemotherapy refractory advanced pancreatic cancer

Renouf, D. J., Hedley, D., Krzyzanowska, M. K., Schmuck, M., Wang, L., Moore, M. J.

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2016

Language:

english

File:

PDF, 438 KB

english, 2016

6

A phase I study of the combination of panitumumab and bevacizumab inKRASwild-type colorectal cancer patients previously treated with fluoropyrimidine, oxaliplatin, irinotecan and bevacizumab

Takahashi, Naoki, Iwasa, Satoru, Fukahori, Masaru, Sudo, Kazuki, Sasaki, Yusuke, Shoji, Hirokazu, Honma, Yoshitaka, Okita, Natsuko Tsuda, Takashima, Atsuo, Hamaguchi, Tetsuya, Boku, Narikazu, Shimada,

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2016

Language:

english

File:

PDF, 986 KB

english, 2016

7

A phase 1 dose-escalation study of NEO-102 in patients with refractory colon and pancreatic cancer

Beg, Muhammad S., Azad, Nilofer S., Patel, Sandip P., Torrealba, Jose, Mavroukakis, Sharon, Beatson, Melony A., Wang, Xue Ping, Arlen, Philip M., Morse, Michael A.

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2016

Language:

english

File:

PDF, 712 KB

english, 2016

8

BSA andABCB1polymorphism affect the pharmacokinetics of sunitinib and its active metabolite in Asian mRCC patients receiving an attenuated sunitinib dosing regimen

Chae, Jung-woo, Teo, Yi Ling, Ho, Han Kiat, Lee, Jaeyeon, Back, Hyun-moon, Yun, Hwi-yeol, Karlsson, Mats O., Kwon, Kwang-il, Chan, Alexandre

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2016

Language:

english

File:

PDF, 702 KB

english, 2016

9

SM-1, a novel PAC-1 derivative, activates procaspase-3 and causes cancer cell apoptosis

Chen, Yanfen, Sun, Meng, Ding, Jingsong, Zhu, Qubo

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2016

Language:

english

File:

PDF, 7.81 MB

english, 2016

10

Model-based prediction of progression-free survival in patients with first-line renal cell carcinoma using week 8 tumor size change from baseline

Claret, Laurent, Zheng, Jenny, Mercier, Francois, Chanu, Pascal, Chen, Ying, Rosbrook, Brad, Yazdi, Pithavala, Milligan, Peter A., Bruno, Rene

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2016

Language:

english

File:

PDF, 754 KB

english, 2016

11

Myelosuppression by chemotherapy in obese patients with gynecological cancers

Kamimura, Kensuke, Matsumoto, Yoshifumi, Zhou, Qiliang, Moriyama, Masato, Saijo, Yasuo

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2016

Language:

english

File:

PDF, 1.07 MB

english, 2016

12

Multicenter phase II study of combination therapy with cetuximab and S-1 in patients withKRASexon 2 wild-type unresectable colorectal cancer previously treated with irinotecan, oxaliplatin, and fluoropyrimidines (KSCC 0901 study)

Takahashi, Takao, Emi, Yasunori, Oki, Eiji, Kobayashi, Kazuma, Tsuji, Akihito, Shimokawa, Mototsugu, Tanaka, Takaho, Akagi, Yoshito, Ogata, Yutaka, Baba, Hideo, Yoshida, Kazuhiro, Natsugoe, Shoji, Mae

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2016

Language:

english

File:

PDF, 607 KB

english, 2016

13

The molecular mechanism of action of superactive human leptin antagonist (SHLA) and quadruple leptin mutein Lan-2 on human ovarian epithelial cell lines

Fiedor, Elżbieta, Gregoraszczuk, Ewa Łucja

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2016

Language:

english

File:

PDF, 2.57 MB

english, 2016

14

Phase II study of a novel taxane (Cabazitaxel-XRP 6258) in previously treated advanced non-small cell lung cancer (NSCLC) patients

Madan, Ankit, Jones, Benjamin S., Bordoni, Rodolfo, Saleh, Mansoor N., Jerome, Mary S., Miley, Deborah K., Jackson, Bradford E., Robert, Francisco

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2016

Language:

english

File:

PDF, 469 KB

english, 2016

15

Effects of a bolus injection of 5-fluorouracil on dihydropyrimidine dehydrogenase activity in rats receiving continuous infusion of 5-fluorouracil

Kobuchi, Shinji, Hayashi, Asuka, Taniguchi, Mayu, Ito, Yukako, Tamura, Takao, Sakaeda, Toshiyuki

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2016

Language:

english

File:

PDF, 487 KB

english, 2016

16

Occurrence of hepatotoxicity with pazopanib and other anti-VEGF treatments for renal cell carcinoma: an observational study utilizing a distributed database network

Shantakumar, Sumitra, Nordstrom, Beth L., Djousse, Luc, Hall, Susan A., Gagnon, David R., Fraeman, Kathy H., van Herk-Sukel, Myrthe, Chagin, Karen, Nelson, Jeanenne

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2016

Language:

english

File:

PDF, 428 KB

english, 2016

17

Repression of phosphoglycerate dehydrogenase sensitizes triple-negative breast cancer to doxorubicin

Zhang, Xia, Bai, Weijun

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2016

Language:

english

File:

PDF, 2.19 MB

english, 2016

18

SLC29A1(ENT1) polymorphisms and outcome of complete remission in acute myeloid leukemia

Kim, Jeong-Hyun, Lee, Chansu, Cheong, Hyun Sub, Koh, Youngil, Ahn, Kwang-Sung, Kim, Hyung-Lae, Shin, Hyoung Doo, Yoon, Sung-Soo

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2016

Language:

english

File:

PDF, 1.58 MB

english, 2016

19

Protein expression of ATP-binding cassette transporters ABCC10 and ABCC11 associates with survival of colorectal cancer patients

Krizkova, V., Dubova, M., Susova, S., Vycital, O., Bruha, J., Skala, M., Liska, V., Daum, O., Soucek, P.

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2016

Language:

english

File:

PDF, 1.64 MB

english, 2016

20

Editorial

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2016

Language:

english

File:

PDF, 172 KB

english, 2016

21

Editorial

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2016

Language:

english

File:

PDF, 158 KB

english, 2016

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