Volume 2; Issue 11

Main
Cancer Discovery
Volume 2; Issue 11

Cancer Discovery

Volume 2; Issue 11

1

PI3K Inhibition Impairs BRCA1/2 Expression and Sensitizes BRCA-Proficient Triple-Negative Breast Cancer to PARP Inhibition

Ibrahim, Y. H., Garcia-Garcia, C., Serra, V., He, L., Torres-Lockhart, K., Prat, A., Anton, P., Cozar, P., Guzman, M., Grueso, J., Rodriguez, O., Calvo, M. T., Aura, C., Diez, O., Rubio, I. T., Perez,

Journal:

Cancer Discovery

Year:

2012

Language:

english

File:

PDF, 610 KB

english, 2012

2

An Antibody-Drug Conjugate Is Effective in HER2-Positive Breast Cancer

Journal:

Cancer Discovery

Year:

2012

Language:

english

File:

PDF, 297 KB

english, 2012

3

Quizartinib Induces Terminal Differentiation in AML Blasts

Journal:

Cancer Discovery

Year:

2012

Language:

english

File:

PDF, 297 KB

english, 2012

4

Fingerprinting Acute Leukemia: DNA Methylation Profiling of B-Acute Lymphoblastic Leukemia

Cimmino, L., Aifantis, I.

Journal:

Cancer Discovery

Year:

2012

Language:

english

File:

PDF, 366 KB

english, 2012

5

Measuring Oncogenic Signaling Pathways in Cancer with PET: An Emerging Paradigm from Studies in Castration-Resistant Prostate Cancer

Journal:

Cancer Discovery

Year:

2012

Language:

english

File:

PDF, 662 KB

english, 2012

6

Combining a PI3K Inhibitor with a PARP Inhibitor Provides an Effective Therapy for BRCA1-Related Breast Cancer

Juvekar, A., Burga, L. N., Hu, H., Lunsford, E. P., Ibrahim, Y. H., Balmana, J., Rajendran, A., Papa, A., Spencer, K., Lyssiotis, C. A., Nardella, C., Pandolfi, P. P., Baselga, J., Scully, R., Asara,

Journal:

Cancer Discovery

Year:

2012

Language:

english

File:

PDF, 2.18 MB

english, 2012

7

Genome-wide DNA Methylation Events in TMPRSS2-ERG Fusion-Negative Prostate Cancers Implicate an EZH2-Dependent Mechanism with miR-26a Hypermethylation

Borno, S. T., Fischer, A., Kerick, M., Falth, M., Laible, M., Brase, J. C., Kuner, R., Dahl, A., Grimm, C., Sayanjali, B., Isau, M., Rohr, C., Wunderlich, A., Timmermann, B., Claus, R., Plass, C., Gra

Journal:

Cancer Discovery

Year:

2012

Language:

english

File:

PDF, 4.08 MB

english, 2012

8

The Potential of Circulating Tumor Cells as a Liquid Biopsy to Guide Therapy in Prostate Cancer

Pantel, K., Alix-Panabieres, C.

Journal:

Cancer Discovery

Year:

2012

Language:

english

File:

PDF, 356 KB

english, 2012

9

Distinct Epigenetic Mechanisms DistinguishTMPRSS2-ERG Fusion-Positive and -Negative Prostate Cancers

Alumkal, J. J., Herman, J. G.

Journal:

Cancer Discovery

Year:

2012

Language:

english

File:

PDF, 4.08 MB

english, 2012

10

Microbial Products Promote IL-23 and IL-17-Mediated Tumor Growth

Journal:

Cancer Discovery

Year:

2012

Language:

english

File:

PDF, 408 KB

english, 2012

11

Integrative Epigenomic Analysis Identifies Biomarkers and Therapeutic Targets in Adult B-Acute Lymphoblastic Leukemia

Geng, H., Brennan, S., Milne, T. A., Chen, W.-Y., Li, Y., Hurtz, C., Kweon, S.-M., Zickl, L., Shojaee, S., Neuberg, D., Huang, C., Biswas, D., Xin, Y., Racevskis, J., Ketterling, R. P., Luger, S. M.,

Journal:

Cancer Discovery

Year:

2012

Language:

english

File:

PDF, 4.26 MB

english, 2012

12

Moores Pushes Clinical Sequencing

Journal:

Cancer Discovery

Year:

2012

Language:

english

File:

PDF, 791 KB

english, 2012

13

FDA Approves Ultrasound Tool

Journal:

Cancer Discovery

Year:

2012

Language:

english

File:

PDF, 240 KB

english, 2012

14

Regorafenib Okayed for Colorectal Cancer

Journal:

Cancer Discovery

Year:

2012

Language:

english

File:

PDF, 584 KB

english, 2012

15

Q&A: George Sledge on Trends in Clinical Trials

Journal:

Cancer Discovery

Year:

2012

Language:

english

File:

PDF, 474 KB

english, 2012

16

Noted

Journal:

Cancer Discovery

Year:

2012

Language:

english

File:

PDF, 630 KB

english, 2012

17

People

Journal:

Cancer Discovery

Year:

2012

Language:

english

File:

PDF, 463 KB

english, 2012

18

Emphasizing the Provocative

Journal:

Cancer Discovery

Year:

2012

Language:

english

File:

PDF, 445 KB

english, 2012

19

Regulatory Domain Conformations Correlate with VEGFR Inhibitor Efficacy

Journal:

Cancer Discovery

Year:

2012

Language:

english

File:

PDF, 407 KB

english, 2012

20

Combined BRAF and MEK Inhibition Improves Outcome in Metastatic Melanoma

Journal:

Cancer Discovery

Year:

2012

Language:

english

File:

PDF, 408 KB

english, 2012

21

A Multifunctional Complex Regulates NOTCH1 Nuclear Activity

Journal:

Cancer Discovery

Year:

2012

Language:

english

File:

PDF, 436 KB

english, 2012

22

Immunoselection Protects against Hyperploidy in Cancer Cells

Journal:

Cancer Discovery

Year:

2012

Language:

english

File:

PDF, 378 KB

english, 2012

23

Focusing on Recalcitrant Cancers

Journal:

Cancer Discovery

Year:

2012

Language:

english

File:

PDF, 679 KB

english, 2012

24

Network Analysis of NRAS Activity Defines a Synergistic Drug Strategy

Journal:

Cancer Discovery

Year:

2012

Language:

english

File:

PDF, 436 KB

english, 2012

25

Varmus Highlights Funding Challenges

Journal:

Cancer Discovery

Year:

2012

Language:

english

File:

PDF, 464 KB

english, 2012

26

Breast Cancer-Associated SNPs Affect Foxa1 Binding

Journal:

Cancer Discovery

Year:

2012

Language:

english

File:

PDF, 408 KB

english, 2012

27

Androgen Receptor Signaling in Circulating Tumor Cells as a Marker of Hormonally Responsive Prostate Cancer

Miyamoto, D. T., Lee, R. J., Stott, S. L., Ting, D. T., Wittner, B. S., Ulman, M., Smas, M. E., Lord, J. B., Brannigan, B. W., Trautwein, J., Bander, N. H., Wu, C.-L., Sequist, L. V., Smith, M. R., Ra

Journal:

Cancer Discovery

Year:

2012

Language:

english

File:

PDF, 1.80 MB

english, 2012

28

The Promise of Combining Inhibition of PI3K and PARP as Cancer Therapy

Rehman, F. L., Lord, C. J., Ashworth, A.

Journal:

Cancer Discovery

Year:

2012

Language:

english

File:

PDF, 426 KB

english, 2012

29

In This Issue

Journal:

Cancer Discovery

Year:

2012

Language:

english

File:

PDF, 774 KB

english, 2012

30

EGFR-Targeting Nanobodies Released by Stem Cells Reduce Tumor Growth

Journal:

Cancer Discovery

Year:

2012

Language:

english

File:

PDF, 411 KB

english, 2012

To build up a library is to create a life. It’s never just a random collection of books.

— Carlos María Domínguez

Official channel

Z-Library Desktop Launcher

Tor version

Z-Library

Z-Library Since 2009 support@z-lib.do

EnglishРусскийEspañolItalianoελληνικάاللغة العربيةBahasa IndonesiaBahasa Malaysiaहिन्दीDeutschFrançaisPortuguêsУкраїнськаPolski中文繁體中文日本語Tiếng ViệtAzərbaycan DiliՀայոց լեզուภาษาไทยTürk Diliქართველიবাংলাپښتوతెలుగుاردو한국어SrpskiБългарски