Volume 2; Issue 8

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Cancer Discovery
Volume 2; Issue 8

Cancer Discovery

Volume 2; Issue 8

1

The Outgrowth of Micrometastases Is Enabled by the Formation of Filopodium-like Protrusions

Shibue, T., Brooks, M. W., Inan, M. F., Reinhardt, F., Weinberg, R. A.

Journal:

Cancer Discovery

Year:

2012

Language:

english

File:

PDF, 1.54 MB

english, 2012

2

A Central Role for RAF->MEK->ERK Signaling in the Genesis of Pancreatic Ductal Adenocarcinoma

Collisson, E. A., Trejo, C. L., Silva, J. M., Gu, S., Korkola, J. E., Heiser, L. M., Charles, R.-P., Rabinovich, B. A., Hann, B., Dankort, D., Spellman, P. T., Phillips, W. A., Gray, J. W., McMahon, M

Journal:

Cancer Discovery

Year:

2012

Language:

english

File:

PDF, 20.39 MB

english, 2012

3

Vismodegib Is Effective in the Treatment and Prevention of BCC

Lewin, P L, Petrov, L A, Hao, L

Journal:

Cancer Discovery

Year:

2012

Language:

english

File:

PDF, 722 KB

english, 2012

4

Cell Lines Often Misidentified

Lewin, P L, Petrov, L A, Hao, L

Journal:

Cancer Discovery

Year:

2012

Language:

english

File:

PDF, 973 KB

english, 2012

5

Mechanisms of BRCA1 Tumor Suppression

Silver, D. P., Livingston, D. M.

Journal:

Cancer Discovery

Year:

2012

Language:

english

File:

PDF, 549 KB

english, 2012

6

Turn Off the IDO: Will Clinical Trials Be Successful?

Novitskiy, S. V., Moses, H. L.

Journal:

Cancer Discovery

Year:

2012

Language:

english

File:

PDF, 465 KB

english, 2012

7

microRNA Regulatory Network Inference Identifies miR-34a as a Novel Regulator of TGF- Signaling in Glioblastoma

Genovese, G., Ergun, A., Shukla, S. A., Campos, B., Hanna, J., Ghosh, P., Quayle, S. N., Rai, K., Colla, S., Ying, H., Wu, C.-J., Sarkar, S., Xiao, Y., Zhang, J., Zhang, H., Kwong, L., Dunn, K., Wiede

Journal:

Cancer Discovery

Year:

2012

Language:

english

File:

PDF, 15.82 MB

english, 2012

8

A Deeper Look at Tumor Heterogeneity

Journal:

Cancer Discovery

Year:

2012

Language:

english

File:

PDF, 728 KB

english, 2012

9

IDO Is a Nodal Pathogenic Driver of Lung Cancer and Metastasis Development

Smith, C., Chang, M. Y., Parker, K. H., Beury, D. W., DuHadaway, J. B., Flick, H. E., Boulden, J., Sutanto-Ward, E., Soler, A. P., Laury-Kleintop, L. D., Mandik-Nayak, L., Metz, R., Ostrand-Rosenberg,

Journal:

Cancer Discovery

Year:

2012

Language:

english

File:

PDF, 16.88 MB

english, 2012

10

Correction: High Frequency of PIK3R1 and PIK3R2 Mutations in Endometrial Cancer Elucidates a Novel Mechanism for Regulation of PTEN Protein Stability

Journal:

Cancer Discovery

Year:

2012

Language:

english

File:

PDF, 1.10 MB

english, 2012

11

Discovery in Context: Leveraging Multidimensional Glioblastoma Datasets to Identify Targetable Regulatory Networks

Babic, I., Mischel, P. S.

Journal:

Cancer Discovery

Year:

2012

Language:

english

File:

PDF, 465 KB

english, 2012

12

Ligand-Independent Adaptor Protein Binding Regulates FGFR2 Activation

Journal:

Cancer Discovery

Year:

2012

Language:

english

File:

PDF, 671 KB

english, 2012

13

Noted

Journal:

Cancer Discovery

Year:

2012

Language:

english

File:

PDF, 414 KB

english, 2012

14

PARP Inhibitors Refocus for Rebound

Journal:

Cancer Discovery

Year:

2012

Language:

english

File:

PDF, 312 KB

english, 2012

15

p53 Protein Dynamics Regulate Signaling Specificity

Journal:

Cancer Discovery

Year:

2012

Language:

english

File:

PDF, 669 KB

english, 2012

16

NCATS-Industry Project Gains Backers

Journal:

Cancer Discovery

Year:

2012

Language:

english

File:

PDF, 1.11 MB

english, 2012

17

Pseudogenes Are Widely Expressed in Human Cancers

Journal:

Cancer Discovery

Year:

2012

Language:

english

File:

PDF, 397 KB

english, 2012

18

Gene Silencing in an Origami Package

Journal:

Cancer Discovery

Year:

2012

Language:

english

File:

PDF, 414 KB

english, 2012

19

KRAS Mutations Underlie Resistance to Anti-EGFR Antibodies

Journal:

Cancer Discovery

Year:

2012

Language:

english

File:

PDF, 669 KB

english, 2012

20

WNT Signaling Enhances the Metastatic Potential of Pancreatic Tumors

Journal:

Cancer Discovery

Year:

2012

Language:

english

File:

PDF, 606 KB

english, 2012

21

Irreversible and Reversible EGFR Inhibitors Are Directly Compared in NSCLC

Journal:

Cancer Discovery

Year:

2012

Language:

english

File:

PDF, 606 KB

english, 2012

22

Q&A: Stephen Friend on a Bioinformation Commons

Journal:

Cancer Discovery

Year:

2012

Language:

english

File:

PDF, 971 KB

english, 2012

23

People

Journal:

Cancer Discovery

Year:

2012

Language:

english

File:

PDF, 1023 KB

english, 2012

24

Somatic Retrotransposition is Common in Epithelial Cancers

Journal:

Cancer Discovery

Year:

2012

Language:

english

File:

PDF, 671 KB

english, 2012

25

An EGF Signaling Pathway Regulates Alternative Splicing

Journal:

Cancer Discovery

Year:

2012

Language:

english

File:

PDF, 444 KB

english, 2012

26

First-in-Human Trial of a STAT3 Decoy Oligonucleotide in Head and Neck Tumors: Implications for Cancer Therapy

Sen, M., Thomas, S. M., Kim, S., Yeh, J. I., Ferris, R. L., Johnson, J. T., Duvvuri, U., Lee, J., Sahu, N., Joyce, S., Freilino, M. L., Shi, H., Li, C., Ly, D., Rapireddy, S., Etter, J. P., Li, P.-K.,

Journal:

Cancer Discovery

Year:

2012

Language:

english

File:

PDF, 16.68 MB

english, 2012

27

RAF/MEK Dependence of KRAS-Mutant Pancreatic Ductal Adenocarcinomas

Hanrahan, A. J., Solit, D. B.

Journal:

Cancer Discovery

Year:

2012

Language:

english

File:

PDF, 964 KB

english, 2012

28

STATe-of-the-Art Approach: Using Oligonucleotide Decoys to Target the "Undruggable"

Koppikar, P., Bromberg, J.

Journal:

Cancer Discovery

Year:

2012

Language:

english

File:

PDF, 480 KB

english, 2012

29

-Catenin Directly Regulates Tert

Journal:

Cancer Discovery

Year:

2012

Language:

english

File:

PDF, 805 KB

english, 2012

30

In This Issue

Journal:

Cancer Discovery

Year:

2012

Language:

english

File:

PDF, 1.66 MB

english, 2012