Volume 4; Issue 2

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Cancer Discovery
Volume 4; Issue 2

Cancer Discovery

Volume 4; Issue 2

1

Addressing Genetic Tumor Heterogeneity through Computationally Predictive Combination Therapy

Zhao, B., Pritchard, J. R., Lauffenburger, D. A., Hemann, M. T.

Journal:

Cancer Discovery

Year:

2014

Language:

english

File:

PDF, 623 KB

english, 2014

2

Navigating the Challenge of Tumor Heterogeneity in Cancer Therapy

Fedele, C., Tothill, R. W., McArthur, G. A.

Journal:

Cancer Discovery

Year:

2014

Language:

english

File:

PDF, 359 KB

english, 2014

3

EMT Twists the Road to PI3K

Niederst, M. J., Benes, C. H.

Journal:

Cancer Discovery

Year:

2014

Language:

english

File:

PDF, 1.11 MB

english, 2014

4

Radiogenomics: Using Genetics to Identify Cancer Patients at Risk for Development of Adverse Effects Following Radiotherapy

Kerns, S. L., Ostrer, H., Rosenstein, B. S.

Journal:

Cancer Discovery

Year:

2014

Language:

english

File:

PDF, 790 KB

english, 2014

5

MYCxing It Up with FGFR1 in Squamous Cell Lung Cancer

Lockwood, W., Politi, K.

Journal:

Cancer Discovery

Year:

2014

Language:

english

File:

PDF, 404 KB

english, 2014

6

MEK-Dependent Negative Feedback Underlies BCR-ABL-Mediated Oncogene Addiction

Asmussen, J., Lasater, E. A., Tajon, C., Oses-Prieto, J., Jun, Y.-w., Taylor, B. S., Burlingame, A., Craik, C. S., Shah, N. P.

Journal:

Cancer Discovery

Year:

2014

Language:

english

File:

PDF, 1.73 MB

english, 2014

7

Epithelial-to-Mesenchymal Transition Rewires the Molecular Path to PI3K-Dependent Proliferation

Salt, M. B., Bandyopadhyay, S., McCormick, F.

Journal:

Cancer Discovery

Year:

2014

Language:

english

File:

PDF, 2.19 MB

english, 2014

8

Comprehensive Genomic Analysis of Rhabdomyosarcoma Reveals a Landscape of Alterations Affecting a Common Genetic Axis in Fusion-Positive and Fusion-Negative Tumors

Shern, J. F., Chen, L., Chmielecki, J., Wei, J. S., Patidar, R., Rosenberg, M., Ambrogio, L., Auclair, D., Wang, J., Song, Y. K., Tolman, C., Hurd, L., Liao, H., Zhang, S., Bogen, D., Brohl, A. S., Si

Journal:

Cancer Discovery

Year:

2014

Language:

english

File:

PDF, 4.70 MB

english, 2014

9

Tolerance of Whole-Genome Doubling Propagates Chromosomal Instability and Accelerates Cancer Genome Evolution

Dewhurst, S. M., McGranahan, N., Burrell, R. A., Rowan, A. J., Gronroos, E., Endesfelder, D., Joshi, T., Mouradov, D., Gibbs, P., Ward, R. L., Hawkins, N. J., Szallasi, Z., Sieber, O. M., Swanton, C.

Journal:

Cancer Discovery

Year:

2014

Language:

english

File:

PDF, 2.84 MB

english, 2014

10

Cell-Autonomous and Non-Cell-Autonomous Mechanisms of Transformation by Amplified FGFR1 in Lung Cancer

Malchers, F., Dietlein, F., Schottle, J., Lu, X., Nogova, L., Albus, K., Fernandez-Cuesta, L., Heuckmann, J. M., Gautschi, O., Diebold, J., Plenker, D., Gardizi, M., Scheffler, M., Bos, M., Seidel, D.

Journal:

Cancer Discovery

Year:

2014

Language:

english

File:

PDF, 3.11 MB

english, 2014

11

Molecular Profiling of the Residual Disease of Triple-Negative Breast Cancers after Neoadjuvant Chemotherapy Identifies Actionable Therapeutic Targets

Balko, J. M., Giltnane, J. M., Wang, K., Schwarz, L. J., Young, C. D., Cook, R. S., Owens, P., Sanders, M. E., Kuba, M. G., Sanchez, V., Kurupi, R., Moore, P. D., Pinto, J. A., Doimi, F. D., Gomez, H.

Journal:

Cancer Discovery

Year:

2014

Language:

english

File:

PDF, 1.61 MB

english, 2014

12

Dasatinib-Letrozole Gets Split Verdict

Journal:

Cancer Discovery

Year:

2014

Language:

english

File:

PDF, 437 KB

english, 2014

13

Glucocorticoid Receptor Activity Bypasses Androgen Receptor Inhibition

Journal:

Cancer Discovery

Year:

2014

Language:

english

File:

PDF, 284 KB

english, 2014

14

pCR Proves Valid Surrogate Endpoint

Journal:

Cancer Discovery

Year:

2014

Language:

english

File:

PDF, 381 KB

english, 2014

15

CTLs Specific for Epstein-Barr Virus Antigens Are Effective in Lymphoma

Journal:

Cancer Discovery

Year:

2014

Language:

english

File:

PDF, 344 KB

english, 2014

16

In This Issue

Journal:

Cancer Discovery

Year:

2014

Language:

english

File:

PDF, 623 KB

english, 2014

17

Chemotherapy Amplifies Genetic Divergence of Recurrent Gliomas

Journal:

Cancer Discovery

Year:

2014

Language:

english

File:

PDF, 371 KB

english, 2014

18

FDA OK's Iclusig's Return to Market

Journal:

Cancer Discovery

Year:

2014

Language:

english

File:

PDF, 229 KB

english, 2014

19

Combined HER2 and mTOR Blockade Shows Activity in Various Solid Tumors

Journal:

Cancer Discovery

Year:

2014

Language:

english

File:

PDF, 365 KB

english, 2014

20

High-Risk Women Should Have BRCA Testing

Journal:

Cancer Discovery

Year:

2014

Language:

english

File:

PDF, 389 KB

english, 2014

21

Antitumor Immune Responses Trigger Autoimmune Disease

Journal:

Cancer Discovery

Year:

2014

Language:

english

File:

PDF, 331 KB

english, 2014

22

China Plans Large Center for PDX Models

Journal:

Cancer Discovery

Year:

2014

Language:

english

File:

PDF, 411 KB

english, 2014

23

NF- B Pathway Activation Determines Drug Sensitivity in Mantle Cell Lymphoma

Journal:

Cancer Discovery

Year:

2014

Language:

english

File:

PDF, 343 KB

english, 2014

24

Mouse Models Identify a Potential Ovarian Cancer Cell of Origin

Journal:

Cancer Discovery

Year:

2014

Language:

english

File:

PDF, 297 KB

english, 2014

25

People

Journal:

Cancer Discovery

Year:

2014

Language:

english

File:

PDF, 335 KB

english, 2014

26

Calreticulin Mutations Are Common in Myeloproliferative Neoplasms

Journal:

Cancer Discovery

Year:

2014

Language:

english

File:

PDF, 371 KB

english, 2014

27

Fine-tuning the Effects of T-cell Therapy

Journal:

Cancer Discovery

Year:

2014

Language:

english

File:

PDF, 364 KB

english, 2014

28

IPI-145 Shows Promise in CLL Patients

Journal:

Cancer Discovery

Year:

2014

Language:

english

File:

PDF, 369 KB

english, 2014

29

Q&A: Muin Khoury on Cancer Epidemiology

Journal:

Cancer Discovery

Year:

2014

Language:

english

File:

PDF, 417 KB

english, 2014

30

Noted

Journal:

Cancer Discovery

Year:

2014

Language:

english

File:

PDF, 421 KB

english, 2014

31

HMGA2 Acts as a ceRNA to Stimulate Lung Cancer Metastasis

Journal:

Cancer Discovery

Year:

2014

Language:

english

File:

PDF, 398 KB

english, 2014

32

The Role of Autophagy in Pancreatic Cancer Is Determined by p53 Status

Journal:

Cancer Discovery

Year:

2014

Language:

english

File:

PDF, 376 KB

english, 2014

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