Volume 207; Issue 9

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Cancer Genetics
Volume 207; Issue 9

Cancer Genetics

Volume 207; Issue 9

1

Chromatin remodeling: from transcription to cancer

Journal:

Cancer Genetics

Year:

2014

Language:

english

File:

PDF, 181 KB

english, 2014

2

Malignant rhabdoid tumor of the liver presented with initial tumor rupture

Kachanov, Denis, Teleshova, Margarita, Kim, Eduard, Dobrenkov, Konstantin, Moiseenko, Roman, Usychkina, Anastasya, Filin, Andrey, Semenkov, Alexey, Mitrofanova, Anna, Konovalov, Dmitry, Shamanskaya, T

Journal:

Cancer Genetics

Year:

2014

Language:

english

File:

PDF, 437 KB

english, 2014

3

Mechanisms by which SMARCB1 loss drives rhabdoid tumor growth

Kim, Kimberly H., Roberts, Charles W.M.

Journal:

Cancer Genetics

Year:

2014

Language:

english

File:

PDF, 1018 KB

english, 2014

4

Clinical and genetic features of rhabdoid tumors of the heart registered with the European Rhabdoid Registry (EU-RHAB)

Bartelheim, Kerstin, Sumerauer, David, Behrends, Uta, Kodetova, Daniela, Kucera, Filip, Leuschner, Ivo, Neumayer, Petra, Oyen, Florian, Rübe, Christian, Siebert, Reiner, Schneppenheim, Reinhard, Seeri

Journal:

Cancer Genetics

Year:

2014

Language:

english

File:

PDF, 1008 KB

english, 2014

5

SMARCB1 mutations in schwannomatosis and genotype correlations with rhabdoid tumors

Smith, Miriam J., Wallace, Andrew J., Bowers, Naomi L., Eaton, Helen, Evans, D. Gareth R.

Journal:

Cancer Genetics

Year:

2014

Language:

english

File:

PDF, 105 KB

english, 2014

6

Identifying molecular markers for the sensitive detection of residual atypical teratoid rhabdoid tumor cells

Vu-Han, Tu-Lan, Frühwald, Michael C., Hasselblatt, Martin, Kerl, Kornelius, Nagel, Inga, Obser, Tobias, Oyen, Florian, Siebert, Reiner, Schneppenheim, Reinhard

Journal:

Cancer Genetics

Year:

2014

Language:

english

File:

PDF, 489 KB

english, 2014

7

Non-rhabdoid pediatric SMARCB1-deficient tumors: overlap between chordomas and malignant rhabdoid tumors?

Renard, Caroline, Pissaloux, Daniel, Decouvelaere, Anne Valérie, Bourdeaut, Franck, Ranchère, Dominique

Journal:

Cancer Genetics

Year:

2014

Language:

english

File:

PDF, 988 KB

english, 2014

8

A gene signature for a long-term survivor of an atypical teratoid/rhabdoid tumor

Sredni, Simone T., Huang, Chiang-Ching, Pundy, Tatiana, Patel, Kashyap, Halpern, Abby L., Grupenmacher, Alex T., Chou, Pauline M., Bonaldo, Maria de Fátima, Tomita, Tadanori

Journal:

Cancer Genetics

Year:

2014

Language:

english

File:

PDF, 389 KB

english, 2014

9

Rhabdoid tumor: the Irish experience 1986–2013

Uwineza, Alice, Gill, Harinder, Buckley, Patrick, Owens, Cormac, Capra, Michael, O'Sullivan, Catriona, McDermott, Michael, Brett, Francesca, Farrell, Michael, Pears, Jane, O'Sullivan, Maureen J.

Journal:

Cancer Genetics

Year:

2014

Language:

english

File:

PDF, 295 KB

english, 2014

10

SMARCB1 deletion by a complex three-way chromosomal translocation in an extrarenal malignant rhabdoid tumor

Bahrami, Armita, Lee, Seungjae, Caradine, Kari D., Raimondi, Susana C., Folpe, Andrew L.

Journal:

Cancer Genetics

Year:

2014

Language:

english

File:

PDF, 940 KB

english, 2014

11

Rhabdoid tumors: integrating biological insights with clinical success

Bourdeaut, Franck, Chi, Susan N., Frühwald, Michael C.

Journal:

Cancer Genetics

Year:

2014

Language:

english

File:

PDF, 239 KB

english, 2014

12

Rhabdoid Tumors: Diagnostic Challenges, Multimodal Treatment and Outcome. Experience From a Single Institution Over the Last 10 Years

Mora, Jaume, Cruz, Ofelia, de Torres, Carmen, Suñol, Mariona

Journal:

Cancer Genetics

Year:

2014

Language:

english

File:

PDF, 71 KB

english, 2014

13

Genomic Analysis Suggests Potential Therapeutic Targets for Atypical Teratoid/Rhabdoid Tumors (AT/RT)

Sredni, Simone Treiger, de Fátima Bonaldo, Maria, Huang, Chiang-Ching, Tomita, Tadanori

Journal:

Cancer Genetics

Year:

2014

Language:

english

File:

PDF, 41 KB

english, 2014

14

Cover 1

Journal:

Cancer Genetics

Year:

2014

File:

PDF, 495 KB

2014

15

Arsenic Trioxide Inhibits Tumor Cell Growth in Malignant Rhabdoid Tumor Cell In Vitro and In Vivo by Targeting Overexpressed Gli1

Kerl, K., Moreno, N., Kool, M., Holsten, T., Mertins, J., Meisterernst, M., Frühwald, M.

Journal:

Cancer Genetics

Year:

2014

Language:

english

File:

PDF, 38 KB

english, 2014

16

A Gene Signature to Identify Long-Survival Atypical Teratoid/Rhabdoid Tumors (AT/RT)

Sredni, Simone Treiger, Huang, Chiang-Ching, de Andrade, Alexandre, Pundy, Tatiana, de Fátima Bonaldo, Maria, Tomita, Tadanori

Journal:

Cancer Genetics

Year:

2014

Language:

english

File:

PDF, 55 KB

english, 2014

17

Schwannomatosis Following an Early Rhabdoid Tumour of the Kidney: The Two Conditions May Coincide

Verkarre, Virginie, Fréneaux, Paul, Pierron, Gaelle, Delattre, Olivier, Michon, Jean, Bourdeaut, Franck

Journal:

Cancer Genetics

Year:

2014

Language:

english

File:

PDF, 30 KB

english, 2014

18

Extra-Cranial Malignant Rhabdoid Tumor in Children: A Single Institute Experience

Hong, Che Ry, Kang, Hyoung Jin, Lee, Ji Won, Park, Sung-Hye, Park, Kyung Duk, Shin, Hee Young

Journal:

Cancer Genetics

Year:

2014

Language:

english

File:

PDF, 43 KB

english, 2014

19

Alterations in IGFBP7 and EGFR/AKT Pathway in SMARCB1 Deficient Tumor Cells

Darr, Jonatan, Klochendler, Agnes, Isaac, Sara, Gordon, Julia, Eden, Amir

Journal:

Cancer Genetics

Year:

2014

Language:

english

File:

PDF, 36 KB

english, 2014

20

Identifying Molecular Markers for the Sensitive Detection of Residual AT/RT Cells

Vu-Han, Tu-Lan, Frühwald, Michael C., Hasselblatt, Martin, Oyen, Florian, Obser, Tobias, Siebert, Reiner, Schneppenheim, Reinhard

Journal:

Cancer Genetics

Year:

2014

Language:

english

File:

PDF, 60 KB

english, 2014

21

CNS AT/RTs are a Heterogeneous Entity That Comprises Subgroups with Distinct Molecular Profiles

Johann, Pascal, Korshunov, Andrey, Kerl, Kornelius, Huang, Annie, Jabado, Nada, Hasselblatt, Martin, Frühwald, Michael, Pfister, Stefan, Kool, Marcel

Journal:

Cancer Genetics

Year:

2014

Language:

english

File:

PDF, 48 KB

english, 2014

22

Expression of Mutant SMARCB1 Proteins in Schwannomas of Schwannomatosis Patients

Hulsebos, Theo, Kenter, Susan, Hans, Volkmar, Verhagen, Wim, Baas, Frank, Flucke, Uta, Wesseling, Pieter

Journal:

Cancer Genetics

Year:

2014

Language:

english

File:

PDF, 67 KB

english, 2014

23

Introduction from the editor

Journal:

Cancer Genetics

Year:

2014

Language:

english

File:

PDF, 125 KB

english, 2014

24

Conditional Inactivation of SMARCB1 in P0 Permissive Mouse Cells Generates Rhabdoid Tumors in the Peripheral Nervous System

Vitte, Jeremie, Chareyre, Fabrice, Stemmer-Rachamimov, Anat, Judkins, Alexander, Giovannini, Marco

Journal:

Cancer Genetics

Year:

2014

Language:

english

File:

PDF, 44 KB

english, 2014

25

A SMARCB1-Deficient, Highly Penetrant Brain Tumour Mouse Model Recapitulates Human AT/RT

Han, Zhi-Yan, Richer, Wilfrid, Lucchesi, Carlo, Fréneaux, Paul, Nicolas, André, Grison, Camille, Plancke, Laetitia, Pierron, Gaelle, Delattre, Olivier, Bourdeaut, Franck

Journal:

Cancer Genetics

Year:

2014

Language:

english

File:

PDF, 44 KB

english, 2014

26

Non Rhabdoid Pediatric SMARCB1-Deficient Tumors: What Diagnosis, for What Treatment?

Renard, Caroline, Pissaloux, Daniel, Decouvelaere, Anne Valérie, Bourdeaut, Franck, Ranchère, Dominique

Journal:

Cancer Genetics

Year:

2014

Language:

english

File:

PDF, 43 KB

english, 2014

27

Involvement of the SWI/SNF Complex in Familial Meningiomatosis

Smith, Miriam J., Sullivan, James O’, Bhaskar, Sanjeev S., Hadfield, Kristen D., Poke, Gemma, Caird, John, Sharif, Saba, Eccles, Diana, Fitzpatrick, David, Rawluk, Daniel, du Plessis, Daniel, van Hoff

Journal:

Cancer Genetics

Year:

2014

Language:

english

File:

PDF, 106 KB

english, 2014

28

Effect of Telomerase Inhibition on Preclinical Models of Malignant Rhabdoid Tumor

Hu, Yafang, Bobb, Daniel, He, Jianping, Dome, Jeffrey S.

Journal:

Cancer Genetics

Year:

2014

Language:

english

File:

PDF, 37 KB

english, 2014

29

Malignant Rhabdoid Tumors of Soft Tissue. Single Center Experience in Russia

Kachanov, Denis, Teleshova, Margarita, Usychkina, Anastasia, Moiseenko, Roman, Muftakhova, Guzel, Mitrofanova, Anna, Shamanskaya, Tatyana, Varfolomeeva, Svetlana

Journal:

Cancer Genetics

Year:

2014

Language:

english

File:

PDF, 73 KB

english, 2014

30

Analysis of the Wnt5b Signaling Pathway to Identify Novel Therapeutics for Atypical Teratoid Rhabdoid Tumors

Bhardwaj, R.D., Hampton, C., Ozols, V., Chakravadhanula, M.

Journal:

Cancer Genetics

Year:

2014

Language:

english

File:

PDF, 62 KB

english, 2014

31

Congenital multifocal rhabdoid tumor: a case with peculiar biological behavior and different response to treatment according to location (central nervous system and kidney)

Pio, Luca, Milanaccio, Claudia, Mascelli, Samantha, Raso, Alessandro, Nozza, Paolo, Sementa, Angela R., Cama, Armando, Buffa, Piero, Avanzini, Stefano, Vannati, Marianna, Capra, Valeria, Lanino, Edoar

Journal:

Cancer Genetics

Year:

2014

Language:

english

File:

PDF, 837 KB

english, 2014

32

Characterising Critical Pathways in Malignant Rhabdoid Tumourigenesis: A Genome-Wide Analysis of Primary Tumours and Functional Genomic Models

Finetti, Martina, Selby, Mathew, Pons, Alicia del Carpio, Bailey, Simon, Clifford, Steve, Williamson, Daniel

Journal:

Cancer Genetics

Year:

2014

Language:

english

File:

PDF, 48 KB

english, 2014

33

Involvement of SMARCB1 in Inherited Predisposition to Schwannoma, Meningioma and Rhabdoid Tumours

Smith, Miriam J., Hadfield, Kristen D., Newman, William G., Evans, D. Gareth

Journal:

Cancer Genetics

Year:

2014

Language:

english

File:

PDF, 44 KB

english, 2014

34

Genomic Alterations in Atypical Teratoid/Rhabdoid Tumors: The Medical University of Vienna Experience

Haberler, Christine, Ströbel, Thomas, Czech, Thomas, Chocholous, Monika, Dorfer, Christian, Slavc, Irene

Journal:

Cancer Genetics

Year:

2014

Language:

english

File:

PDF, 43 KB

english, 2014

35

Synchronous congenital malignant rhabdoid tumor of the orbit and atypical teratoid/rhabdoid tumor—feasibility and efficacy of multimodal therapy in a long-term survivor

Seeringer, Angela, Reinhard, Harald, Hasselblatt, Martin, Schneppenheim, Reinhard, Siebert, Reiner, Bartelheim, Kerstin, Leuschner, Ivo, Frühwald, Michael C.

Journal:

Cancer Genetics

Year:

2014

Language:

english

File:

PDF, 1.16 MB

english, 2014

36

Clinical Characteristics and Outcome of Children with Extracranial, Extrarenal Rhabdoid Tumors Registered to the European Rhabdoid Registry 2007–2013

Bartelheim, K., Seeringer, A., Leuschner, I., Schenk, J.P., Timmermann, B., Rübe, C., Graf, N., Koscielniak, E., Schneppenheim, R., Siebert, R., Frühwald, M.C.

Journal:

Cancer Genetics

Year:

2014

Language:

english

File:

PDF, 56 KB

english, 2014

37

Durable Tumor Regression in Genetically Altered Malignant Rhabdoid Tumors by Inhibition of EZH2

Heike, Keilhack

Journal:

Cancer Genetics

Year:

2014

Language:

english

File:

PDF, 58 KB

english, 2014

38

Successful Treatment of Malignant Rhabdoid Tumor of the Liver Presented With Initial Tumor Rupture

Kachanov, Denis, Moiseenko, Roman, Usychkina, Anastasia, Kim, Eduard, Muftakhova, Guzel, Mitrofanova, Anna, Shamanskaya, Tatyana, Varfolomeeva, Svetlana

Journal:

Cancer Genetics

Year:

2014

Language:

english

File:

PDF, 52 KB

english, 2014

39

Case Report of a Patient With Speech Delay and Behavioral Disorders Associated with Neuroblastoma. Possible Role of SMARCA4

Defachelles, Anne-Sophie, Clément, Nathalie, Duban-Bedu, Bénédicte, Boidein, Françoise, Pierron, Gaëlle, Ferrand, Sandrine, Peuchmaur, Michel, Delattre, Olivier, Bourdeaut, Franck, Schleiermacher, Gud

Journal:

Cancer Genetics

Year:

2014

Language:

english

File:

PDF, 39 KB

english, 2014

40

Prognostic Value of Clinical, Histopathological and Molecular Features in AT/RT

Hasselblatt, Martin, Brokinkel, Benjamin, Bartelheim, Kerstin, Schneppenheim, Reinhard, Siebert, Reiner, Frühwald, Michael

Journal:

Cancer Genetics

Year:

2014

Language:

english

File:

PDF, 37 KB

english, 2014

41

Congenital Rhabdoid Tumors – Feasibility of Aggressive Multimodal Therapy in the Youngest

Seeringer, Angela, Bartelheim, Kerstin, Bourdeaut, Franck, Graf, Norbert, Frühwald, Michael C.

Journal:

Cancer Genetics

Year:

2014

Language:

english

File:

PDF, 65 KB

english, 2014

42

Integrative Genomic Analyses of Atypical Teratoid Rhabdoid Tumours (ATRTs)

Torchia, Jonathon, Picard, Daniel, Kwang, Dong Anh, Dzamba, Misko, Ho, King Ching, Kim, Seoung-Ki, Louterneau, Louis, Lafay-Cousin, Lucie, Chan, Tiffany S.Y., Golbourn, Brian, Morrissy, Sorana, Birks,

Journal:

Cancer Genetics

Year:

2014

Language:

english

File:

PDF, 69 KB

english, 2014

43

Effect of telomerase inhibition on preclinical models of malignant rhabdoid tumor

Hu, Yafang, Bobb, Daniel, Lu, Yunbiao, He, Jianping, Dome, Jeffrey S.

Journal:

Cancer Genetics

Year:

2014

Language:

english

File:

PDF, 1.77 MB

english, 2014

44

Pattern of Relapse After Radiotherapy in Children with Cerebral Atypical Teratoid and Rhabdoid Tumors (AT/RT)

Beneyton, V., Lavergne, E., Dufour, C., Carrie, C.

Journal:

Cancer Genetics

Year:

2014

Language:

english

File:

PDF, 41 KB

english, 2014

45

Malignant Rhabdoid Tumor of the Kidney (MRTK) – Data of 52 Patients Treated According to Protocols of the GPOH (German Society of Paediatric Oncology and Haematology)

Furtwängler, R., Nourkami-Tutibi, N., Leuschner, I., Niggli, F., Kager, L., Frühwald, M.C., Graf, N.

Journal:

Cancer Genetics

Year:

2014

Language:

english

File:

PDF, 37 KB

english, 2014

46

Cytoplasmic Interaction of the Tumour Suppressor Protein hSNF5 with Dynamin-2 Controls Endocytosis

Alfonso-Perez, T., Dominguez, M.G., Reyes, J.C.

Journal:

Cancer Genetics

Year:

2014

Language:

english

File:

PDF, 55 KB

english, 2014

47

SNF5/INI1 Deficiency Destabilizes the SWI/SNF Complex During Malignant Rhabdoid Tumor Development

Kuwahara, Yasumichi, Wei, Darmood, Song, Shujie, Cannon, Courtney, Sakellariou-Thompson, Donastas, Emanuele, Michael, Hosoi, Hajime, Weissman, Bernard E.

Journal:

Cancer Genetics

Year:

2014

Language:

english

File:

PDF, 106 KB

english, 2014

48

Atypical Teratoid Rhabdoid Tumours (AT/RT): A French Retrospective Study

Bertozzi, Anne-Isabelle, Munzer, Caroline, Fouyssac, Fanny, André, Nicolas, Boetto, Stephane, Leblond, Pierre, Bourdeaut, Franck, Dufour, Christelle

Journal:

Cancer Genetics

Year:

2014

Language:

english

File:

PDF, 39 KB

english, 2014

49

Expression of the HOX genes and HOTAIR in atypical teratoid rhabdoid tumors and other pediatric brain tumors

Chakravadhanula, Madhavi, Ozols, Victor V., Hampton, Chris N., Zhou, Li, Catchpoole, Daniel, Bhardwaj, Ratan D.

Journal:

Cancer Genetics

Year:

2014

Language:

english

File:

PDF, 594 KB

english, 2014

50

Loss of NOXA Expression by INI1/SNF5 Loss Impaired Sensitivity to Chemotherapeutic Agents in Malignant Rhabdoid Tumor

Ouchi, Kazutaka, Kuwahara, Yasumichi, Iehara, Tomoko, Hosoi, Hajime

Journal:

Cancer Genetics

Year:

2014

Language:

english

File:

PDF, 36 KB

english, 2014

51

Malignant rhabdoid tumor of the kidney: significantly improved response to pre-operative treatment intensified with doxorubicin

Furtwängler, Rhoikos, Nourkami-Tutdibi, Nasinien, Leuschner, Ivo, Vokuhl, Christian, Niggli, Felix, Kager, Leo, Ebinger, Martin, Frühwald, Michael C., Graf, Norbert

Journal:

Cancer Genetics

Year:

2014

Language:

english

File:

PDF, 253 KB

english, 2014

52

Activity of Alisertib (MLN8237) as Single Agent in Recurrent Atypical Teratoid Rhabdoid Tumor (AT/RT) in Four Children: A Single Patient Treatment Plan Pilot Study

Wetmore, C., Bendel, A., Gajjar, A.

Journal:

Cancer Genetics

Year:

2014

Language:

english

File:

PDF, 41 KB

english, 2014

53

Pathology and diagnosis of SMARCB1-deficient tumors

Margol, Ashley S., Judkins, Alexander R.

Journal:

Cancer Genetics

Year:

2014

Language:

english

File:

PDF, 4.08 MB

english, 2014

54

Detection of an ATRT Brain Tumor Gene Deletion Diagnostic in Circulating Blood using Next Gen Sequencing

Chakravadhanula, Madhavi, Tembe, Waibhav, Legendre, Christophe, Carpentieri, David, Liang, Winnie S., Bussey, Kimberly J., Carpten, John, Berens, Michael E., Bhardwaj, Ratan D.

Journal:

Cancer Genetics

Year:

2014

Language:

english

File:

PDF, 44 KB

english, 2014

55

Arsenic Trioxide Inhibits Growth of Rhabdoid Cell Line KD

Ebinger, Martin, Handgretinger, Rupert, Schleicher, Sabine

Journal:

Cancer Genetics

Year:

2014

Language:

english

File:

PDF, 61 KB

english, 2014

56

Fatal Metachronous Supratentorial AT/RT in an Infant Successfully Treated for a Neonatal Extra-Renal non CNS-Rhabdoid Tumour INI1 Negative

Opocher, Enrico, Alaggio, Rita, Gardiman, Marina, Morali, Laura, Viscardi, Elisabetta, Bisogno, Gianni

Journal:

Cancer Genetics

Year:

2014

Language:

english

File:

PDF, 43 KB

english, 2014

57

Neurocognitive Evaluation of Long Term Survivor’s Patients with AT/RT

Fay-McClymont, Taryn, Lafay-Cousin, Lucie, Janzen, Laura, Guger, Sharon, Bouffet, Eric, Huang, Annie, Mabbott, Donald

Journal:

Cancer Genetics

Year:

2014

Language:

english

File:

PDF, 37 KB

english, 2014

58

Malignant Extracranial Tumors of Childhood and Adolescence With Loss of SMARCB1/INI1 Expression

Journal:

Cancer Genetics

Year:

2014

Language:

english

File:

PDF, 59 KB

english, 2014

59

Rhabdoid Tumours of Brain, Liver, Kidney and Soft-Parts: Expression Profiles Suggest Common Features but Different Entities.

Richer, Wilfrid, Lucchesi, Carlo, Lequin, Delphine, Pierron, Gaelle, Buendia, Marie-Annick, Ranchère, Dominique, Williamson, Dan, Delattre, Olivier, Bourdeaut, Franck

Journal:

Cancer Genetics

Year:

2014

Language:

english

File:

PDF, 41 KB

english, 2014

60

Analysis of 57 Cases Non-Epithelioid Type Pediatric INI1-Negative Sarcomas

Mitrofanova, A., Konovalov, D., Kislyakov, A., Rogozhin, D.

Journal:

Cancer Genetics

Year:

2014

Language:

english

File:

PDF, 37 KB

english, 2014

61

Phosphoprotemic Analysis of Snf5 Deficient Tumor Cells Reveals Activation of EGFr Signaling Which Is Dependent Upon Snf5 Expression

Darr, Jonatan, Geiger, Tami, klochendler, Agnes, Gordon, Julia, Isacc, Sara, Mann, Matthias, Eden, Amir

Journal:

Cancer Genetics

Year:

2014

Language:

english

File:

PDF, 36 KB

english, 2014

62

Rhabdoid Tumour (RT): A Case Report with Peculiar Biological Behaviour and Results of Treatment (Tx) According to Different Location (CNS and Kidney)

Milanaccio, Claudia, Pio, Luca, Vannati, Mariana, Nozza, Paolo, Raso, Alessandra, Sementa, Angela, Cama, Armando, Buffa, Piero, Mascelli, Samantha, Capra, Valeria, Giardino, Stefano, Amoroso, Loredana

Journal:

Cancer Genetics

Year:

2014

Language:

english

File:

PDF, 53 KB

english, 2014

63

Editorial Board

Journal:

Cancer Genetics

Year:

2014

File:

PDF, 108 KB

2014

64

Table of Contents

Journal:

Cancer Genetics

Year:

2014

Language:

english

File:

PDF, 68 KB

english, 2014

65

Atypical Teratoid Rhabdoid Tumor (AT/RT): Improved Long-Term Survival with an Intensive Multimodal Therapy and Delayed Radiotherapy. The Medical University of Vienna Experience 1992–2012

Slavc, Irene, Chocholous, Monika, Leiss, Ulrike, Haberler, Christine, Peyrl, Andreas, Azizi, Amedeo A., Dieckmann, Karin, Woehrer, Adelheid, Peters, Christina, Widhalm, Georg, Dorfer, Christian, Czech

Journal:

Cancer Genetics

Year:

2014

Language:

english

File:

PDF, 45 KB

english, 2014

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