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Volume 68; Issue 19

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Cancer Research
Volume 68; Issue 19

Cancer Research

Volume 68; Issue 19

1

PIK3CA Cooperates with Other Phosphatidylinositol 3'-Kinase Pathway Mutations to Effect Oncogenic Transformation

Oda, K., Okada, J., Timmerman, L., Rodriguez-Viciana, P., Stokoe, D., Shoji, K., Taketani, Y., Kuramoto, H., Knight, Z. A., Shokat, K. M.

Journal:

Cancer Research

Year:

2008

Language:

english

File:

PDF, 1003 KB

english, 2008

2

A Double-Negative Feedback Loop between ZEB1-SIP1 and the microRNA-200 Family Regulates Epithelial-Mesenchymal Transition

Bracken, C. P., Gregory, P. A., Kolesnikoff, N., Bert, A. G., Wang, J., Shannon, M. F., Goodall, G. J.

Journal:

Cancer Research

Year:

2008

Language:

english

File:

PDF, 718 KB

english, 2008

3

Alteration of the Mitochondrial Apoptotic Pathway Is Key to Acquired Paclitaxel Resistance and Can Be Reversed by ABT-737

Kutuk, O., Letai, A.

Journal:

Cancer Research

Year:

2008

Language:

english

File:

PDF, 810 KB

english, 2008

4

Optimized Clostridium-Directed Enzyme Prodrug Therapy Improves the Antitumor Activity of the Novel DNA Cross-Linking Agent PR-104

Liu, S.-C., Ahn, G-O., Kioi, M., Dorie, M.-J., Patterson, A. V., Brown, J. M.

Journal:

Cancer Research

Year:

2008

Language:

english

File:

PDF, 640 KB

english, 2008

5

NVP-BEZ235, a Dual PI3K/mTOR Inhibitor, Prevents PI3K Signaling and Inhibits the Growth of Cancer Cells with Activating PI3K Mutations

Serra, V., Markman, B., Scaltriti, M., Eichhorn, P. J.A., Valero, V., Guzman, M., Botero, M. L., Llonch, E., Atzori, F., Di Cosimo, S., Maira, M., Garcia-Echeverria, C., Parra, J. L., Arribas, J., Bas

Journal:

Cancer Research

Year:

2008

Language:

english

File:

PDF, 682 KB

english, 2008

6

Vitamin C Antagonizes the Cytotoxic Effects of Antineoplastic Drugs

Heaney, M. L., Gardner, J. R., Karasavvas, N., Golde, D. W., Scheinberg, D. A., Smith, E. A., O'Connor, O. A.

Journal:

Cancer Research

Year:

2008

Language:

english

File:

PDF, 476 KB

english, 2008

7

Lapatinib (Tykerb, GW572016) Reverses Multidrug Resistance in Cancer Cells by Inhibiting the Activity of ATP-Binding Cassette Subfamily B Member 1 and G Member 2

Dai, C.-l., Tiwari, A. K., Wu, C.-P., Su, X.-d., Wang, S.-R., Liu, D.-g., Ashby, C. R., Huang, Y., Robey, R. W., Liang, Y.-j., Chen, L.-m., Shi, C.-J., Ambudkar, S. V., Chen, Z.-S., Fu, L.-w.

Journal:

Cancer Research

Year:

2008

Language:

english

File:

PDF, 539 KB

english, 2008

8

Abnormal DNA Methylation of CD133 in Colorectal and Glioblastoma Tumors

Yi, J. M., Tsai, H.-C., Glockner, S. C., Lin, S., Ohm, J. E., Easwaran, H., James, C. D., Costello, J. F., Riggins, G., Eberhart, C. G., Laterra, J., Vescovi, A. L., Ahuja, N., Herman, J. G., Schuebel

Journal:

Cancer Research

Year:

2008

Language:

english

File:

PDF, 622 KB

english, 2008

9

The History of Tumor Virology

Javier, R. T., Butel, J. S.

Journal:

Cancer Research

Year:

2008

Language:

english

File:

PDF, 1.00 MB

english, 2008

10

Senescence-Associated Exosome Release from Human Prostate Cancer Cells

Lehmann, B. D., Paine, M. S., Brooks, A. M., McCubrey, J. A., Renegar, R. H., Wang, R., Terrian, D. M.

Journal:

Cancer Research

Year:

2008

Language:

english

File:

PDF, 332 KB

english, 2008

11

MicroRNA-21 Targets a Network of Key Tumor-Suppressive Pathways in Glioblastoma Cells

Papagiannakopoulos, T., Shapiro, A., Kosik, K. S.

Journal:

Cancer Research

Year:

2008

Language:

english

File:

PDF, 518 KB

english, 2008

12

The Mammary Progenitor Marker CD61/ 3 Integrin Identifies Cancer Stem Cells in Mouse Models of Mammary Tumorigenesis

Vaillant, F., Asselin-Labat, M.-L., Shackleton, M., Forrest, N. C., Lindeman, G. J., Visvader, J. E.

Journal:

Cancer Research

Year:

2008

Language:

english

File:

PDF, 613 KB

english, 2008

13

Autophagy: A Novel Mechanism of Synergistic Cytotoxicity between Doxorubicin and Roscovitine in a Sarcoma Model

Lambert, L. A., Qiao, N., Hunt, K. K., Lambert, D. H., Mills, G. B., Meijer, L., Keyomarsi, K.

Journal:

Cancer Research

Year:

2008

Language:

english

File:

PDF, 599 KB

english, 2008

14

Hepatocyte Growth Factor and Sonic Hedgehog Expression in Cerebellar Neural Progenitor Cells Costimulate Medulloblastoma Initiation and Growth

Binning, M. J., Niazi, T., Pedone, C. A., Lal, B., Eberhart, C. G., Kim, K. J., Laterra, J., Fults, D. W.

Journal:

Cancer Research

Year:

2008

Language:

english

File:

PDF, 420 KB

english, 2008

15

Correction: Bmx Signaling in Irradiated Vascular Endothelium

Journal:

Cancer Research

Year:

2008

Language:

english

File:

PDF, 105 KB

english, 2008

16

ATM and the Mre11-Rad50-Nbs1 Complex Respond to Nucleoside Analogue-Induced Stalled Replication Forks and Contribute to Drug Resistance

Ewald, B., Sampath, D., Plunkett, W.

Journal:

Cancer Research

Year:

2008

Language:

english

File:

PDF, 827 KB

english, 2008

17

Anterior Gradient 2 Is Expressed and Secreted during the Development of Pancreatic Cancer and Promotes Cancer Cell Survival

Ramachandran, V., Arumugam, T., Wang, H., Logsdon, C. D.

Journal:

Cancer Research

Year:

2008

Language:

english

File:

PDF, 523 KB

english, 2008

18

Targeting XIAP Bypasses Bcl-2-Mediated Resistance to TRAIL and Cooperates with TRAIL to Suppress Pancreatic Cancer Growth In vitro and In vivo

Vogler, M., Walczak, H., Stadel, D., Haas, T. L., Genze, F., Jovanovic, M., Gschwend, J. E., Simmet, T., Debatin, K.-M., Fulda, S.

Journal:

Cancer Research

Year:

2008

Language:

english

File:

PDF, 1.25 MB

english, 2008

19

Identification of Transformation-Related Pathways in a Breast Epithelial Cell Model Using a Ribonomics Approach

Mazan-Mamczarz, K., Hagner, P. R., Dai, B., Wood, W. H., Zhang, Y., Becker, K. G., Liu, Z., Gartenhaus, R. B.

Journal:

Cancer Research

Year:

2008

Language:

english

File:

PDF, 679 KB

english, 2008

20

Nuclear Survivin Abrogates Multiple Cell Cycle Checkpoints and Enhances Viral Oncolysis

Connell, C. M., Wheatley, S. P., McNeish, I. A.

Journal:

Cancer Research

Year:

2008

Language:

english

File:

PDF, 658 KB

english, 2008

21

Glucagon-like Peptide-2 Does Not Modify the Growth or Survival of Murine or Human Intestinal Tumor Cells

Koehler, J. A., Harper, W., Barnard, M., Yusta, B., Drucker, D. J.

Journal:

Cancer Research

Year:

2008

Language:

english

File:

PDF, 560 KB

english, 2008

22

Activation of Signal Transducer and Activator of Transcription 3 through a Phosphomimetic Serine 727 Promotes Prostate Tumorigenesis Independent of Tyrosine 705 Phosphorylation

Qin, H. R., Kim, H.-J., Kim, J.-Y., Hurt, E. M., Klarmann, G. J., Kawasaki, B. T., Duhagon Serrat, M. A., Farrar, W. L.

Journal:

Cancer Research

Year:

2008

Language:

english

File:

PDF, 508 KB

english, 2008

23

Mutations in the Focal Adhesion Targeting Region of Deleted in Liver Cancer-1 Attenuate Their Expression and Function

Liao, Y.-C., Shih, Y.-P., Lo, S. H.

Journal:

Cancer Research

Year:

2008

Language:

english

File:

PDF, 409 KB

english, 2008

24

Prolyl Isomerase Cyclophilin A Regulation of Janus-Activated Kinase 2 and the Progression of Human Breast Cancer

Zheng, J., Koblinski, J. E., Dutson, L. V., Feeney, Y. B., Clevenger, C. V.

Journal:

Cancer Research

Year:

2008

Language:

english

File:

PDF, 686 KB

english, 2008

25

Runx2 Transcriptional Activation of Indian Hedgehog and a Downstream Bone Metastatic Pathway in Breast Cancer Cells

Pratap, J., Wixted, J. J., Gaur, T., Zaidi, S. K., Dobson, J., Gokul, K. D., Hussain, S., van Wijnen, A. J., Stein, J. L., Stein, G. S., Lian, J. B.

Journal:

Cancer Research

Year:

2008

Language:

english

File:

PDF, 651 KB

english, 2008

26

SLITs Suppress Tumor Growth In vivo by Silencing Sdf1/Cxcr4 within Breast Epithelium

Marlow, R., Strickland, P., Lee, J. S., Wu, X., PeBenito, M., Binnewies, M., Le, E. K., Moran, A., Macias, H., Cardiff, R. D., Sukumar, S., Hinck, L.

Journal:

Cancer Research

Year:

2008

Language:

english

File:

PDF, 963 KB

english, 2008

27

Dietary Induction of Colonic Tumors in a Mouse Model of Sporadic Colon Cancer

Yang, K., Kurihara, N., Fan, K., Newmark, H., Rigas, B., Bancroft, L., Corner, G., Livote, E., Lesser, M., Edelmann, W., Velcich, A., Lipkin, M., Augenlicht, L.

Journal:

Cancer Research

Year:

2008

Language:

english

File:

PDF, 656 KB

english, 2008

28

Disruption of NAD(P)H:Quinone Oxidoreductase 1 Gene in Mice Leads to Radiation-Induced Myeloproliferative Disease

Iskander, K., Barrios, R. J., Jaiswal, A. K.

Journal:

Cancer Research

Year:

2008

Language:

english

File:

PDF, 556 KB

english, 2008

29

The Polycomb Gene Product BMI1 Contributes to the Maintenance of Tumor-Initiating Side Population Cells in Hepatocellular Carcinoma

Chiba, T., Miyagi, S., Saraya, A., Aoki, R., Seki, A., Morita, Y., Yonemitsu, Y., Yokosuka, O., Taniguchi, H., Nakauchi, H., Iwama, A.

Journal:

Cancer Research

Year:

2008

Language:

english

File:

PDF, 778 KB

english, 2008

30

Maintenance of Constitutive I B Kinase Activity by Glycogen Synthase Kinase-3 / in Pancreatic Cancer

Wilson, W., Baldwin, A. S.

Journal:

Cancer Research

Year:

2008

Language:

english

File:

PDF, 549 KB

english, 2008

31

Pericentromeric Instability and Spontaneous Emergence of Human Neoacrocentric and Minute Chromosomes in the Alternative Pathway of Telomere Lengthening

Gagos, S., Chiourea, M., Christodoulidou, A., Apostolou, E., Raftopoulou, C., Deustch, S., Jefford, C.-E., Irminger-Finger, I., Shay, J. W., Antonarakis, S. E.

Journal:

Cancer Research

Year:

2008

Language:

english

File:

PDF, 855 KB

english, 2008

32

Ectopic Expression of P-Cadherin Correlates with Promoter Hypomethylation Early in Colorectal Carcinogenesis and Enhanced Intestinal Crypt Fission In vivo

Milicic, A., Harrison, L.-A., Goodlad, R. A., Hardy, R. G., Nicholson, A. M., Presz, M., Sieber, O., Santander, S., Pringle, J. H., Mandir, N., East, P., Obszynska, J., Sanders, S., Piazuelo, E., Shaw

Journal:

Cancer Research

Year:

2008

Language:

english

File:

PDF, 638 KB

english, 2008

33

Androgenic Control of Transforming Growth Factor- Signaling in Prostate Epithelial Cells through Transcriptional Suppression of Transforming Growth Factor- Receptor II

Song, K., Wang, H., Krebs, T. L., Kim, S.-J., Danielpour, D.

Journal:

Cancer Research

Year:

2008

Language:

english

File:

PDF, 673 KB

english, 2008

34

A Bicistronic CYCLIN D1-TROP2 mRNA Chimera Demonstrates a Novel Oncogenic Mechanism in Human Cancer

Guerra, E., Trerotola, M., Dell' Arciprete, R., Bonasera, V., Palombo, B., El-Sewedy, T., Ciccimarra, T., Crescenzi, C., Lorenzini, F., Rossi, C., Vacca, G., Lattanzio, R., Piantelli, M., Alberti, S.

Journal:

Cancer Research

Year:

2008

Language:

english

File:

PDF, 394 KB

english, 2008

35

Breast Tumor Kinase Phosphorylates p190RhoGAP to Regulate Rho and Ras and Promote Breast Carcinoma Growth, Migration, and Invasion

Shen, C.-H., Chen, H.-Y., Lin, M.-S., Li, F.-Y., Chang, C.-C., Kuo, M.-L., Settleman, J., Chen, R.-H.

Journal:

Cancer Research

Year:

2008

Language:

english

File:

PDF, 610 KB

english, 2008

36

Prostaglandin E2 Regulates Tumor Angiogenesis in Prostate Cancer

Jain, S., Chakraborty, G., Raja, R., Kale, S., Kundu, G. C.

Journal:

Cancer Research

Year:

2008

Language:

english

File:

PDF, 901 KB

english, 2008

37

Functional Analysis of a Cell Cycle-Associated, Tumor-Suppressive Gene, Protein Tyrosine Phosphatase Receptor Type G, in Nasopharyngeal Carcinoma

Cheung, A. K. L., Lung, H. L., Hung, S. C., Law, E. W. L., Cheng, Y., Yau, W. L., Bangarusamy, D. K., Miller, L. D., Liu, E. T.-B., Shao, J.-Y., Kou, C.-W., Chua, D., Zabarovsky, E. R., Tsao, S. W., S

Journal:

Cancer Research

Year:

2008

Language:

english

File:

PDF, 694 KB

english, 2008

38

Cell Cycle-Dependent Variation of a CD133 Epitope in Human Embryonic Stem Cell, Colon Cancer, and Melanoma Cell Lines

Jaksch, M., Munera, J., Bajpai, R., Terskikh, A., Oshima, R. G.

Journal:

Cancer Research

Year:

2008

Language:

english

File:

PDF, 341 KB

english, 2008

39

Pancreatic Stellate Cells and Pancreatic Cancer Cells: An Unholy Alliance

Vonlaufen, A., Phillips, P. A., Xu, Z., Goldstein, D., Pirola, R. C., Wilson, J. S., Apte, M. V.

Journal:

Cancer Research

Year:

2008

Language:

english

File:

PDF, 290 KB

english, 2008

40

CD8+ T-Cell Responses against Hemoglobin- Prevent Solid Tumor Growth

Komita, H., Zhao, X., Taylor, J. L., Sparvero, L. J., Amoscato, A. A., Alber, S., Watkins, S. C., Pardee, A. D., Wesa, A. K., Storkus, W. J.

Journal:

Cancer Research

Year:

2008

Language:

english

File:

PDF, 592 KB

english, 2008

41

Heterogeneity of Receptor Function in Colon Carcinoma Cells Determined by Cross-talk between Type I Insulin-like Growth Factor Receptor and Epidermal Growth Factor Receptor

Hu, Y. P., Patil, S. B., Panasiewicz, M., Li, W., Hauser, J., Humphrey, L. E., Brattain, M. G.

Journal:

Cancer Research

Year:

2008

Language:

english

File:

PDF, 1.28 MB

english, 2008

42

Cancer Immunotherapy Targeting the High Molecular Weight Melanoma-Associated Antigen Protein Results in a Broad Antitumor Response and Reduction of Pericytes in the Tumor Vasculature

Maciag, P. C., Seavey, M. M., Pan, Z.-K., Ferrone, S., Paterson, Y.

Journal:

Cancer Research

Year:

2008

Language:

english

File:

PDF, 486 KB

english, 2008

43

Correction: GSK-3 in Radiation Injury to Hippocampal Neurons

Journal:

Cancer Research

Year:

2008

Language:

english

File:

PDF, 109 KB

english, 2008

44

The Melanoma-Associated Antigen A3 Mediates Fibronectin-Controlled Cancer Progression and Metastasis

Liu, W., Cheng, S., Asa, S. L., Ezzat, S.

Journal:

Cancer Research

Year:

2008

Language:

english

File:

PDF, 730 KB

english, 2008

45

SCL/TAL1 Interrupting Locus Derepresses GLI1 from the Negative Control of Suppressor-of-Fused in Pancreatic Cancer Cell

Kasai, K., Inaguma, S., Yoneyama, A., Yoshikawa, K., Ikeda, H.

Journal:

Cancer Research

Year:

2008

Language:

english

File:

PDF, 646 KB

english, 2008

46

Regulation of Estrogenic Effects by Beclin 1 in Breast Cancer Cells

John, S., Nayvelt, I., Hsu, H.-C., Yang, P., Liu, W., Das, G. M., Thomas, T., Thomas, T.J.

Journal:

Cancer Research

Year:

2008

Language:

english

File:

PDF, 498 KB

english, 2008

47

Tbx3 Represses E-Cadherin Expression and Enhances Melanoma Invasiveness

Rodriguez, M., Aladowicz, E., Lanfrancone, L., Goding, C. R.

Journal:

Cancer Research

Year:

2008

Language:

english

File:

PDF, 585 KB

english, 2008

48

Chromosomal Instability in Unirradiated Hemaopoietic Cells Induced by Macrophages Exposed In vivo to Ionizing Radiation

Lorimore, S. A., Chrystal, J. A., Robinson, J. I., Coates, P. J., Wright, E. G.

Journal:

Cancer Research

Year:

2008

Language:

english

File:

PDF, 197 KB

english, 2008

49

The RNA Helicase p68 Is a Novel Androgen Receptor Coactivator Involved in Splicing and Is Overexpressed in Prostate Cancer

Clark, E. L., Coulson, A., Dalgliesh, C., Rajan, P., Nicol, S. M., Fleming, S., Heer, R., Gaughan, L., Leung, H. Y., Elliott, D. J., Fuller-Pace, F. V., Robson, C. N.

Journal:

Cancer Research

Year:

2008

Language:

english

File:

PDF, 586 KB

english, 2008

50

Presentation of Telomerase Reverse Transcriptase, a Self-Tumor Antigen, is Down-regulated by Histone Deacetylase Inhibition

Pellicciotta, I., Cortez-Gonzalez, X., Sasik, R., Reiter, Y., Hardiman, G., Langlade-Demoyen, P., Zanetti, M.

Journal:

Cancer Research

Year:

2008

Language:

english

File:

PDF, 710 KB

english, 2008

51

Brn-2 Represses Microphthalmia-Associated Transcription Factor Expression and Marks a Distinct Subpopulation of Microphthalmia-Associated Transcription Factor-Negative Melanoma Cells

Goodall, J., Carreira, S., Denat, L., Kobi, D., Davidson, I., Nuciforo, P., Sturm, R. A., Larue, L., Goding, C. R.

Journal:

Cancer Research

Year:

2008

Language:

english

File:

PDF, 609 KB

english, 2008

52

RNAi-Mediated Silencing of Nuclear Factor Erythroid-2-Related Factor 2 Gene Expression in Non-Small Cell Lung Cancer Inhibits Tumor Growth and Increases Efficacy of Chemotherapy

Singh, A., Boldin-Adamsky, S., Thimmulappa, R. K., Rath, S. K., Ashush, H., Coulter, J., Blackford, A., Goodman, S. N., Bunz, F., Watson, W. H., Gabrielson, E., Feinstein, E., Biswal, S.

Journal:

Cancer Research

Year:

2008

Language:

english

File:

PDF, 560 KB

english, 2008

53

Dual Roles for Coactivator Activator and its Counterbalancing Isoform Coactivator Modulator in Human Kidney Cell Tumorigenesis

Kang, Y. K., Schiff, R., Ko, L., Wang, T., Tsai, S. Y., Tsai, M.-J., O'Malley, B. W.

Journal:

Cancer Research

Year:

2008

Language:

english

File:

PDF, 815 KB

english, 2008

54

Suppression of Prostate Cancer Nodal and Systemic Metastasis by Blockade of the Lymphangiogenic Axis

Burton, J. B., Priceman, S. J., Sung, J. L., Brakenhielm, E., An, D. S., Pytowski, B., Alitalo, K., Wu, L.

Journal:

Cancer Research

Year:

2008

Language:

english

File:

PDF, 1015 KB

english, 2008

55

Evaluation of Cancer Tests of 1,3-Butadiene Using Internal Dose, Genotoxic Potency, and a Multiplicative Risk Model

Fred, C., Tornqvist, M., Granath, F.

Journal:

Cancer Research

Year:

2008

Language:

english

File:

PDF, 297 KB

english, 2008

56

Validation of the p21-Activated Kinases as Targets for Inhibition in Neurofibromatosis Type 2

Yi, C., Wilker, E. W., Yaffe, M. B., Stemmer-Rachamimov, A., Kissil, J. L.

Journal:

Cancer Research

Year:

2008

Language:

english

File:

PDF, 515 KB

english, 2008

57

Endothelial p70 S6 Kinase 1 in Regulating Tumor Angiogenesis

Liu, L.-Z., Zheng, J. Z., Wang, X.-R., Jiang, B.-H.

Journal:

Cancer Research

Year:

2008

Language:

english

File:

PDF, 509 KB

english, 2008

58

Potent In vitro and In vivo Activity of an Fc-Engineered Anti-CD19 Monoclonal Antibody against Lymphoma and Leukemia

Horton, H. M., Bernett, M. J., Pong, E., Peipp, M., Karki, S., Chu, S. Y., Richards, J. O., Vostiar, I., Joyce, P. F., Repp, R., Desjarlais, J. R., Zhukovsky, E. A.

Journal:

Cancer Research

Year:

2008

Language:

english

File:

PDF, 367 KB

english, 2008

59

Development of Cellular Immune Responses against PAX5, a Novel Target for Cancer Immunotherapy

Yan, M., Himoudi, N., Pule, M., Sebire, N., Poon, E., Blair, A., Williams, O., Anderson, J.

Journal:

Cancer Research

Year:

2008

Language:

english

File:

PDF, 450 KB

english, 2008

60

Addiction to Elevated Insulin-like Growth Factor I Receptor and Initial Modulation of the AKT Pathway Define the Responsiveness of Rhabdomyosarcoma to the Targeting Antibody

Cao, L., Yu, Y., Darko, I., Currier, D., Mayeenuddin, L. H., Wan, X., Khanna, C., Helman, L. J.

Journal:

Cancer Research

Year:

2008

Language:

english

File:

PDF, 569 KB

english, 2008