Volume 34; Issue supp-S1

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Cancer Treatment Reviews
Volume 34; Issue supp-S1

Cancer Treatment Reviews

Volume 34; Issue supp-S1

1

Bone loss in patients with breast cancer receiving aromatase inhibitors and associated treatment strategies

Robert E. Coleman, Jean-Jacques Body, Julie R. Gralow, Allan Lipton

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 346 KB

english, 2008

2

Antitumor effects of bisphosphonates: Promising preclinical evidence

Theresa A. Guise

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 394 KB

english, 2008

3

Guidance for the management of breast cancer treatment-induced bone loss: A consensus position statement from a UK Expert Group

David M. Reid, Julie Doughty, Richard Eastell, Steven D. Heys, Anthony Howell, Eugene V. McCloskey, Trevor Powles, Peter Selby, Robert E. Coleman

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 555 KB

english, 2008

4

Emerging role of bisphosphonates in the clinic—Antitumor activity and prevention of metastasis to bone

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 230 KB

english, 2008

5

President’s Welcome

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 79 KB

english, 2008

6

CIBD VII Schedule of Events

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 80 KB

english, 2008

7

PL1.3. Developments in bone target treatment of cancer

G. David Roodman

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 81 KB

english, 2008

8

PL2.1. M for invasion: Morphology, mutation and the microenvironment

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 89 KB

english, 2008

9

PL2.2. Proteolytic enzymes

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 25 KB

english, 2008

10

PL2.3. Adhesion molecules

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 25 KB

english, 2008

11

PL3.2. Wnt signaling in malignancy

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 26 KB

english, 2008

12

PL6.1. Osteoblast activation in solid tumours

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 33 KB

english, 2008

13

PL6.2. Bone cell–tumor cell interactions in prostate cancer

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 25 KB

english, 2008

14

PL7.2. PET and bone metastases

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 35 KB

english, 2008

15

PL8.1. Bisphosphonates: Where do they go and what do they do?

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 27 KB

english, 2008

16

PL8.2. Use of biochemical markers to monitor therapy in metastatic bone disease

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 27 KB

english, 2008

17

PL8.3. Bone targeted therapy

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 39 KB

english, 2008

18

PL8.4. Radioisotope treatment of bone metastases

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 31 KB

english, 2008

19

PL9.1. The importance of patient reported outcomes (PROs) in determining efficacy of treatment

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 39 KB

english, 2008

20

OC1. Translating a novel urine test for early detection and accurate assessment of bone abnormalities

Darren Hillegonds, Robert Fitzgerald, Douglas Burton, Meng Yang, Thomas Walczyk, Srinivasan Vijayakumar, David Herold, Leonard Deftos, John Vogel

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 28 KB

english, 2008

21

OC2. Efficacy, pharmacokinetics, and safety of a cathepsin K (Cat K) inhibitor in the suppression of bone resorption in women with breast cancer and established bone 2

Christopher Wynne, Anders Bonde Jensen, Steinar Lundgren, Jose Joaquin Caicedo, Maximiliano Ontaneda, Anish Mehta, Sui Yan, Shabana Ather, Weili He, Yang Song, Yuliya Berd, Antonio Lombardi

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 41 KB

english, 2008

22

OC3. Farnesoid X receptor (FXR): A new marker for the prediction of bone metastases in breast cancer

Fabrice Journe, Virginie Durbecq, Carole Chaboteaux, Ghislane Rouas, Benjamin Haibe-Kains, Hichame IdBoufker, Guy Laurent, Christos Sotiriou, Denis Larsimont, Jean-Jacques Body

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 33 KB

english, 2008

23

OC4. Number and sites of bone lesions and history of skeletal-related events (SREs): Do these parameters correspond with skeletal morbidity and mortality in patients with bone metastases (mets) from hormone-refractory prostate cancer (HRPC)?

Fred Saad, Pierre Major, Dany Habr, Richard Cook

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 42 KB

english, 2008

24

OC5. Prevention of anastrozole induced bone loss with monthly oral ibandronate during adjuvant breast cancer therapy: Two year results from the ARIBON study

James Lester, David Dodwell, Omprakash Purohit, Sandra Gutcher, Sue Ellis, Ruth Thorpe, Janet Horsman, Janet Brown, Rosemary Hannon, Robert Coleman

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 39 KB

english, 2008

25

OC6. Endo180 function in metastatic prostate cancer bone lesions

Giolanta Kogianni, Kyriacos Eleftheriou, Jonathan Waxman, Justin P. Cobb, Justin Sturge

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 30 KB

english, 2008

26

OC7. Inhibiting dickkopf-1 (Dkk-1) prevents the development of osteolytic bone disease in multiple myeloma

Debby Heath, Andrew Chantry, Clive Buckle, Les Coulton, John Shaughnessy Jr., Holly Evans, David Stover, Karin Vanderkerken, Peter Croucher

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 28 KB

english, 2008

27

OC8. Essential role of host bone marrow-derived stromal cells in the initial establishment and progression of multiple myeloma

Jessica Fowler, Seint Lwin, Greg Mundy, Claire Edwards

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 28 KB

english, 2008

28

OC9. A role for B cell suppression in a pre-clinical model of multiple myeloma

Jessica Fowler, Greg Mundy, Claire Edwards

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 30 KB

english, 2008

29

OC10. Prognosis and skeletal disease course in patients with bone metastases from breast cancer (BC) and normal baseline levels of N-telopeptide of type I collagen (NTX)

Allan Lipton, Jean-Jacques Body, Richard Cook, Robert Coleman

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 30 KB

english, 2008

30

OC11. Effect of anastrozole on bone mineral density after one year of treatment: Results from bone sub-study of the International Breast Cancer Prevention Study (IBIS-II)

Shalini Singh, Jack Cuzick, Sheila Ferguson, Glen Blake, John Truscott, Rob Coleman, Richard Eastel, Anthony Howell

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 39 KB

english, 2008

31

OC12. Specific inhibition of the VEGF homolog placental growth factor is protective against osteolytic bone metastasis in mice

Lieve Coenegrachts, Christa Maes, Sophie Torrekens, Riet Van Looveren, Massimiliano Mazzone, Theresa A. Guise, Roger Bouillon, Peter Carmeliet, Geert Carmeliet

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 31 KB

english, 2008

32

OC13. Development of the European organization for research and treatment of cancer bone metastases module (BMM) (EORTC QLQ-BM22)

Amanda Hird, Edward Chow

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 40 KB

english, 2008

33

OC14. Osteolysis and the generation of osteoclast-myeloma hybrid cells are related to the myeloma cell-induced collapse of the vascular bone remodeling compartments

Thomas Levin Andersen, Kent Søe, Teis Esben Sondergaard, Katarzyna Kupisiewicz, Torben Plesner, Jean-Marie Delaisse

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 30 KB

english, 2008

34

OC15. Potential influence of zoledronic acid on primary tumour response during neoadjuvant chemotherapy for breast cancer

Matthew Winter, Helen Thorpe, Roger Burkinshaw, Samantha Beevers, Robert Coleman

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 38 KB

english, 2008

35

P1. Breast cancer cells cause a reduction in osteoblast number – An early event in the development of osteolytic bone lesions

Penelope Ottewell, Peter Croucher, Ingunn Holen

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 28 KB

english, 2008

36

P2. Proteasome inhibition enhances anti-myeloma and anti-osteoclastic effects of glucocorticoids and weakens the anti-osteoblastic effects

Kent Soe, Thomas L. Andersen, Torben Plesner, Jean-Marie Delaisse

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 28 KB

english, 2008

37

P3. A soluble activin type II receptor prevents the development of myeloma bone disease

Andrew Chantry, Deborah Heath, Les Coulton, Holly Evans, Nicole Abdul, Jas Seehra, Karin Vanderkerken, Peter Croucher

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 39 KB

english, 2008

38

P4. Poorly structured bone matrix, reminiscent of an “osteoblastic” lesion, promotes an aggressive gene expression profile in prostate carcinoma cells in vitro

Anne Delany, Katherine Lowther, Kristen Kapinas, Catherine Kessler, Oleg Nadiarnykh, Paul Campagnola

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 31 KB

english, 2008

39

P5. A dual osteoclastic and metalloproteolytic mechanism is required for bone colonization in lung cancer metastasis

Diego Luis-Ravelo, Silvestre Vicent, Iker Antón, Ignacio García-Tuñón, Carolina Zandueta, Susana Martínez, Javier De Las Rivas, Fernando Lecanda

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 41 KB

english, 2008

40

P6. Anti-resorptive and potential anti-invasion effects of a cathepsin K inhibitor in the treatment of breast cancer-induced bone metastasis

Patrick Leung, Maureen Pickarski, Gregg A. Wesolowski, Le T. Duong

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 31 KB

english, 2008

41

P7. The ADP receptor P2Y12 is expressed in developing osteoclasts and is required for full osteoclast function and tumor associated osteolysis

Desiree Floyd, Kaiming Wu, Angela Hirbe, Ozge Uluckan, Mark Eagleton, Pam Conley, Katherine Weilbaecher

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 31 KB

english, 2008

42

P8. Osteoclast dysfunction in CD47−/− mice suppresses metastatic tumor burden and osteolysis

Ozge Uluckan, Hongju Deng, Julie L. Prior, David Piwnica-Worms, William A. Frazier, Katherine N. Weilbaecher

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 40 KB

english, 2008

43

Poster Withdrawn

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 29 KB

english, 2008

44

P10. Disease modeling and tissue engineering: Breast cancer metastasis to bone

Michaela Reagan, Lidia Faverman, Robert Goldstein, Michael Rosenblatt, David Kaplan

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 29 KB

english, 2008

45

P11. Fly to mouse: A new approach to cancer metastasis

Emanuela Heller, Marcos Vidal, Lorena Salavaggione, Lourdes Ylagan, Mark Watson, Mark Wilkins, Jill Fink, Ross Cagan, Katherine Weilbaecher

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 40 KB

english, 2008

46

P12. Poster Withdrawn

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 31 KB

english, 2008

47

P13. The RANKL inhibitor OPG-Fc delays the de novo establishment of breast cancer skeletal metastases in an MDA-MB-231 mouse model

Jude Canon, Rebecca Bryant, Robert Miller, Ryan Erwert, Martine Roudier, Angela Coxon, William Dougall

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 31 KB

english, 2008

48

P14. Development and characterization of a new renal cell carcinoma (RCC) bone metastasis mouse model

Anne Strube, Elizaveta Stepina, Bernd Hartmann, Ina Neumann, Peter Hauff, Sanna-Maria Käkönen

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 31 KB

english, 2008

49

P60. Skeletal metastases in malignant melanoma

Kiran Kandukurti, Jamal Zekri, Maria Marples, Janet Brown

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 29 KB

english, 2008

50

P15. Zoledronic acid modulates chromosome separation in breast cancer cells by inhibition of Cenp-F prenylation

Hannah K. Brown, Ingunn Holen

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 43 KB

english, 2008

51

P16. Hypoxia and breast cancer bone metastasis: HIF-1α enhances TGF-β signaling and expression of prometastatic factors CXCR4 and VEGF

Lauren Kingsley, Pierrick Fournier, John Chirgwin, Theresa Guise

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 31 KB

english, 2008

52

P17. A humanized model of breast cancer metastasis revealing a human-specific metastasis gene signature

Robert Goldstein, Kristen Anderson, Jodie Moreau, Michael Rosenblatt

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 31 KB

english, 2008

53

P18. Mechanisms of apoptosis and cell cycle arrest in intra-tibial breast tumours treated sequentially with doxorubicin followed by zoledronic acid

Penelope Ottewell, Robert Coleman, Ingunn Holen

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 32 KB

english, 2008

54

P19. Role of noggin in osteolytic bone metastasis

Chiara Secondini, Ruth Schwaninger, Antoinette Wetterwald, George N. Thalmann, Marco G. Cecchini

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 32 KB

english, 2008

55

P20. Autotaxin promotes metastasis dissemination of breast cancer cells

Marion David, Estelle Wannecq, Sandra Grès, Blandine Deux, Claire Marie Serre, Nathalie Bendriss-Vermare, Christophe Caux, Jean-Sébastien Saulnier-Blache, Philippe Clézardin, Olivier Peyruchaud

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 42 KB

english, 2008

56

P21. Myeloma cells decrease EphB4 expression in osteoblasts: A novel mechanism for regulation of bone formation in multiple myeloma

Andreia Bates, Gregory Mundy, Claire Edwards

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 29 KB

english, 2008

57

P22. Host-derived MMP9 promotes progression of multiple myeloma in vivo

Claire Edwards, Conor Lynch, Jessica Fowler, Kathy Carter, Seint Lwin, Lynn Matrisian, Gregory Mundy

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 29 KB

english, 2008

58

P23. Inhibitory effects of baicalein, baicalin and wogonin on osteolytic bone metastasis of breast cancer

Ji-Hee Won, Kwang-Kyun Park, Won-Yoon Chung

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 39 KB

english, 2008

59

P24. The effect of platycodin D on tumor-induced osteolysis in breast cancer bone metastasis

Sun Kyoung Lee, Kwang Kyun Park, Yeong-Shik Kim, Young-Wan Ha, Won Yoon Chung

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 32 KB

english, 2008

60

P25. TACE up-regulation in monocytes by GM-CSF and IL-4 disrupts myeloma cell-induced osteoclastogenesis while inducing dendritic cell differentiation

Masahiro Abe, Masahiro Hiasa, Shinsuke Kido, Asuka Oda, Hiroe Amou, Kyoko Takeuchi, Kenichiro Yata, Shuji Ozaki, Toshio Matsumoto

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 38 KB

english, 2008

61

P26. MicroRNA expression profiling and functional screening in bone metastatic breast cancer cells

Sirkku Pollari, Kirsi Hellström, Saija Haapa-Paananen, Suvi-Katri Leivonen, Pekka Kohonen, Niko Sahlberg, Merja Perälä, Sanna-Maria Käkönen, Matthias Nees, Olli Kallioniemi

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 28 KB

english, 2008

62

P27. Molecular interactions of disseminated tumor cells with the microenvironment of the bone marrow

Yvonne Schueler, Tatjana Kaiser, Cornelia Thedieck, Tanja Fehm, Gerd Klein

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 28 KB

english, 2008

63

P28. Biological prerequisites for heterotypic fusion between myeloma cells and osteoclasts

Katarzyna Kupisiewicz, Kent Soe, Thomas Levin Andersen, Teis Esben Soendergaard, Thomas Lund, Torben Plesner, Jean-Marie Delaisse

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 38 KB

english, 2008

64

P29. Validation of an in vitro method to study the interactions between bone and prostate cancer cells

Ase Tieva, Jonas Nilsson, Ulf Lerner, Anders Widmark

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 29 KB

english, 2008

65

P30. New models of osteoblastic bone metastasis: VCaP and DuCaP prostate cancer cell lines

Ruth Schwaninger, Antoinette Wetterwald, George Thalmann, Marco Cecchini

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 40 KB

english, 2008

66

P31. Real-time imaging of signaling pathway activity in osteotropic cancers in vivo

Geertje van der Horst, Petra P.G.M. van Overveld, Jeroen Buijs, Niek Henriquez, Ivo Que, Henry Cheung, Gabri van der Pluijm

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 31 KB

english, 2008

67

P32. Transforming growth factor-β (TGF-β) promotes prostate cancer bone metastases: Increased expression of pro-osteolytic genes and of PMEPA1, a new TGF-β signalling regulator

Pierrick Fournier, Gregory Clines, John Chirgwin, Theresa Guise

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 31 KB

english, 2008

68

P33. Role of SMAD2 and SMAD3 in breast cancer metastasis to bone

Maj Petersen, Martine Deckers, Geertje van der Horst, Gabri van der Pluijm, Evangelia Pardali

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 41 KB

english, 2008

69

P34. Melanoma-induced osteolysis is directly mediated through osteoclast formation and activity

James Edwards, Logan Dumitrescu, Julie Sterling, Andreia Bates, Gregory Mundy

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 29 KB

english, 2008

70

P35. Wnt signaling regulates Gli2 expression in human breast cancer cells that cause osteolysis

Julie Sterling, Rachelle Johnson, Alayna Roberts, Xiaohong Li, Neil Bhowmick, Gregory Mundy

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 42 KB

english, 2008

71

P36. The role of FGF-signalling in osteosarcoma: A potential therapeutic target?

Daniel Weekes, Takeshi Kashima, Agamemnin Grigoriadis

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 31 KB

english, 2008

72

P37. The in vivo impact of host MMP-2 to mammary tumor growth induced osteolysis

Sophie Thiolloy, Conor Lynch, Barbara Fingleton, Gregory Mundy, Lynn Matrisian

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 31 KB

english, 2008

73

P38. RANKL plays a role in migration and invasion of the bone-seeking cell line MDA-MB-231-BO2 and regulates MMP1 and MMP9 expression

Sandra Casimiro, Irina Alho, Afonso Fernandes, Allan Lipton, Theresa Guise, Luis Costa

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 44 KB

english, 2008

74

P39. Rapamycin and the downstream target of mTOR, ribosomal protein L29 (RPL29), regulate prostate cancer cell growth and bone metastatic potential

Lynn Schwarting-Opdenaker, Daniel Carson, Mary C. Farach-Carson

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 33 KB

english, 2008

75

P61. Identification of serum lactate dehydrogenase (LDH) as a significant prognostic variable for survival: Multivariate analysis in women with metastatic breast cancer (BC)

Robert Coleman, Janet Brown, Richard Cook

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 39 KB

english, 2008

76

P62. Prognostic variables for occurrence of skeletal-related events (SREs) in patients with breast cancer metastatic to bone: A multivariate analysis

Janet Brown, Richard Cook, Robert Coleman

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 31 KB

english, 2008

77

P40. Calcium-sensing receptor mediates the effect of elevated extracellular calcium concentrations on PTHrP secretion and expression in human lung squamous cell carcinoma lines

Gwendolen Lorch, Serge Viatchenko-Karpinski, Wessel Dirksen, Sandor Gyorke, Ramiro Toribio, Thomas Rosol

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 33 KB

english, 2008

78

P41. Bone cancer pain: The crosstalk between prostate tumour cells and osteocytes upregulates expression and release of pain mediators

Walter Pyerin, Sabrina Schroeck, Karin Ackermann

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 42 KB

english, 2008

79

P42. Bone cell reactions to cancer stress: Metastases and multiple myeloma generate distinct transcriptional footprints in osteocytes in vivo

Karin Ackermann, Sabine Eisenberger, Walter Pyerin

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 29 KB

english, 2008

80

P43. Cells of the osteoblast lineage increase the expression of bone-related and invasiveness genes in breast cancer cells

Hichame IdBoufker, Laurence Lagneaux, Tatiana Tondreau, Hugues Duvillier, Jean-Jacques Body, Fabrice Journe

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 41 KB

english, 2008

81

P44. Negative prognostic genes are induced by procollagen COOH trimer in breast carcinoma cells and angiogenesis is induced in xenograft tumors

Daniela Palmieri, Paola Manduca, Stefano Zanotti, Ottavia Barbieri, Simonetta Astigiano

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 32 KB

english, 2008

82

P63. Not a tumour of bone: Just osteopoikilosis

Serdar Toker, Aysun Toker, Erim Gulcan

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 39 KB

english, 2008

83

P64. Skeletal related events (SREs) in patients with bone metastases from breast cancer treated with intravenous (i.v.) bisphosphonates (BPs) in the non-trial setting

Mateya Trinkaus, Christine Simmons, Jeffrey Myers, George Dranitsaris, Mark Clemons

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 29 KB

english, 2008

84

P65. Efficacy of second-line zoledronate for bone metastases of breast cancer after first-line treatment with pamidronate

Hiroyoshi Miura, Shunji Takahashi, Naomi Tokudome, Yoshinori Ito, Kiyohiko Hatake

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 29 KB

english, 2008

85

P66. Poster Withdrawn

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 29 KB

english, 2008

86

P67. Bone mineral density in men on long term androgen deprivation therapy for prostate cancer

Mick Button, Mike Stone, Rebecca Pettit, Rebekah Ellaway, John Staffurth

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 38 KB

english, 2008

87

P68. Which IV bisphosphonates must be used after initiating androgen deprivation therapy in patients submitted to radical prostatectomy experiencing recurrence? A prospective open-label controlled study

Paulo Rodrigues, Flavio Hering, Alex Meler, Paulo Bruna

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 30 KB

english, 2008

88

P69. Determining relevant quality of life issues for bone metastases patients: Differences in perspectives

Amanda Hird, Edward Chow

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 30 KB

english, 2008

89

P70. Bony metastases in renal cell carcinoma – An audit of patterns of disease and bisphosphonate use in patients treated in Leeds, UK

Katy Clarke, Satinder Jagdev, Alex Newsham, Joan Lister, Kate Hayward, Krishna Sastry, Peter Selby, Janet Brown

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 39 KB

english, 2008

90

P71. The bone degradation marker CTX is a unique marker for disease progression in multiple myeloma

Thomas Lund, Jean-Marie Delaissé, Niels Abildgaard, Katarzyna Kupisiewicz, Torben Plesner

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 29 KB

english, 2008

91

P72. Dexamethasone for the prophylaxis of radiation-induced pain flare following palliative radiotherapy for bone metastases: A phase II study

Jenna van Draanen, Amanda Hird, Carlo DeAngelis, Edward Chow, Andrew Loblaw, Rebecca Wong, Jackson Wu

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 29 KB

english, 2008

92

P73. Pain flare following radiotherapy for painful bone metastases: A joint effort of three cancer centres to determine the incidence

Jenna van Draanen, Amanda Hird, Carlo DeAngelis, Andrew Loblaw, Rebecca Wong, Jackson Wu, Edward Chow

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 39 KB

english, 2008

93

P74. Bone scan imaging before and after intravenous bisphosphonate therapy for osseous metastases from breast cancer

Catherine Van Poznak, Ravinder Grewal, Patrick Morris, Shanu Modi

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 30 KB

english, 2008

94

P75. One-hour infusion of clodronate disodium for treating oncological pain due to bone metastases of solid tumors among adults

Silvia Regina Graziani, Silvana Maria Graziani, Nadia Aparecida Bossa, Roberto Hegg, Raul Cavalcante Maranhão

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 38 KB

english, 2008

95

P45. TNF-related apoptosis-inducing ligand (TRAIL) inhibits primary bone tumor growth and augments survival in a human model Ewing sarcoma

Loic Geffroy, Damien Chauvière, François Lamoureux, Gaelle Picarda, Susan Burchill, Olivier Delattre, Pascal Delépine, François Gouin, Dominique Heymann, Françoise Rédini

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 32 KB

english, 2008

96

P46. Proteoglycans are potential regulators of osteoprotegerin (OPG) antitumoral and anti-bone resorption activities in osteosarcoma

François Lamoureux, Gaelle Picarda, Valérie Trichet, Bruno Pitard, Dominique Heymann, Françoise Rédini

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 41 KB

english, 2008

97

P47. Therapeutic efficacy of soluble receptor activator of NF-kappaB delivered by non-viral gene transfer in a mouse model of osteolytic osteosarcoma

François Lamoureux, Gaelle Picarda, Julie Rousseau, Clothilde Gourden, Séverine Battaglia, Céline Charrier, Bruno Pitard, Dominique Heymann, Françoise Rédini

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 30 KB

english, 2008

98

P48. Transforming growth factor β receptor I kinase inhibitor and bisphosphonates are additive to reduce breast cancer bone metastases

Khalid Mohammad, Elizabeth Stebbins, Lauren Kingsley, Pierrick Fournier, Maria Niewolna, Christopher McKenna, Xianhong Peng, Linda Higgins, Darren Wong, Theresa Guise

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 43 KB

english, 2008

99

P49. Zoledronic acid-induced IPP accumulation in cancer cells strongly correlates with γδ T-cell mediated cancer cell death

Hannu Monkkonen, Ismahene Benzaid, Verena Stresing, Jonathan Green, Jukka Monkkonen, Jean-Louis Touraine, Philippe Clezardin

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 33 KB

english, 2008

100

P50. Osteotropic poly(d,l-lactide-co-glycolide)-alendronate nanoparticles for the treatment of bone cancer

Elisabetta Cenni, Manuela Salerno, Caterina Fotia, Sofia Avnet, Donatella Granchi, Francesco Castelli, Dorotea Micieli, Rosario Pignatello, Mattia Capulli, Nadia Rucci, Anna Teti, Nicola Baldini

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 33 KB

english, 2008

101

P77. Guided bone regeneration for bisphosphonate-induced osteonecrosis of the jaws

Pierre Mouret, Hervé Moizan, Mihaela Muresan, Eric Gerard, Bernard Montinet

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 29 KB

english, 2008

102

P51. RAP-011, a soluble activin receptor type IIA IgG-Fc-fusion protein, is a novel bone anabolic agent that prevents bone loss and skeletal metastases in a mouse model of metastatic breast cancer

Aaron Mulivor, Ravi Kumar, Amelia Pearsall, Kathryn Underwood, Jeff Ucran, Matthew Sherman, Jasbir Seehra, R. Scott Pearsall

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 43 KB

english, 2008

103

P78. NHS resource use and capacity planning in breast cancer patients with metastatic bone disease treated with IV zoledronic acid or oral ibandronic acid

Robert Grieve, Kate Peperell, Elizabeth Hamilton

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 41 KB

english, 2008

104

P52. The IKK inhibitors celastrol and parthenolide inhibit breast cancer cell proliferation and migration in vitro and osteolytic bone metastasis in vivo

Aymen Idris, Helene Libouban, Hervé Nyangoga, Euphemie Landao-Bassonga, Daniel Chappard, Stuart Ralston

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 32 KB

english, 2008

105

P53. Osteonecrosis of the jaw and dental related adverse events during adjuvant therapy for early breast cancer: Initial dental safety findings from the AZURE study

Roger Burkinshaw, Matt Winter, Helen Thorpe, Jon Pedlar, Rob Coleman

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 41 KB

english, 2008

106

P54. Evaluating the Wilms’ tumour antigen 1 as a target for the immunotherapy of prostate cancer

Judy King, Roberto Dina, Jonathan Waxman, Hans Stauss

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 29 KB

english, 2008

107

P55. Targeting of αv integrins in prostate cancer and bone stroma inhibits bone metastasis formation and progression

Geertje van der Horst, Christel van den Hoogen, Jeroen Buijs, Henry Cheung, Jean Feyen, Philippe Pujuguet, Rob Pelger, Bertrand Heckmann, Philippe Clément-Lacroix, Gabri van der Pluijm

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 38 KB

english, 2008

108

P56. Targeting VEGF and its receptors in the treatment of breast cancer bone metastases

Richard Bachelier, Vincent Gonin, Delphine Goehrig, Blandine Deux, Philippe Clézardin

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 29 KB

english, 2008

109

P57. Manipulating the bone mineral affinity of bisphosphonates to directly target cancer cells in the bone marrow

Florence Daubiné, Pierrick Fournier, Hal Ebetino, Philippe Clezardin

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 29 KB

english, 2008

110

P79. N-Telopeptide of type I collagen (NTX) levels and prognosis in patients with bone metastases from non-small cell lung cancer (NSCLC) receiving zoledronic acid (ZOL) or placebo

Vera Hirsh, Pierre Major, Allan Lipton, Richard Cook, Corey Langer, Matthew Smith, Janet Brown, Robert Coleman

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 32 KB

english, 2008

111

P80. Minimally invasive treatment of tumour related vertebral compression fractures and other metastatic bone lesions

Emily Sinclair, Michael Ford, Lori Holden, Edward Chow

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 38 KB

english, 2008

112

P81. Meta-analysis of effects of zoledronic acid (ZOL) on survival in patients with metastatic bone disease (MBD) and high bone turnover

Robert Coleman, Richard Cook, Fred Saad, Vera Hirsh, Pierre Major, Rosh Dias, Allan Lipton

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 27 KB

english, 2008

113

P58. An etidronate–aracytidine conjugate inhibits osteolysis and allodynia in a rodent model of prostate cancer induced bone disease

Alexander Karpeisky, Shawn Zinnen

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 38 KB

english, 2008

114

P59. CT-based structural rigidity reflects treatment response in an osteolytic rat model

Ara Nazarian, Michael Bohanske, Peer van der Zwaal, Frederic Hoogwater, Brian Snyder

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 29 KB

english, 2008

115

PL1.1. Preparing the soil – the bone marrow niche

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 81 KB

english, 2008

116

PL1.2. Tumour-bone cell interactions in malignancy

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 81 KB

english, 2008

117

PL2.4. PTHrP and non-collagenous bone proteins

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 25 KB

english, 2008

118

PL3.1. Prostate cancer stem cells and the metastatic process

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 26 KB

english, 2008

119

PL4 Prediction of bone disease and metastasis

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 26 KB

english, 2008

120

PL4.1. Genetic predisposition to bone disease

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 26 KB

english, 2008

121

PL4.2. Genetic signatures and prediction of bone metastasis

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 26 KB

english, 2008

122

PL4.3. Circulating Tumour cells and tumour DNA

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 26 KB

english, 2008

123

PL5 Bone biology and the Bone Microenvironment

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 26 KB

english, 2008

124

PL5.1. RANK ligand signaling system in malignancy

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 26 KB

english, 2008

125

PL5.2. Osteoblast inactivation in myeloma

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 26 KB

english, 2008

126

PL7.1. Developments in Preclinical Imaging

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 25 KB

english, 2008

127

PL9.2. Haematopoeitic cell and growth factor – tumour cell interactions

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 28 KB

english, 2008

128

PL9.3. Is the antitumour efficacy of bisphosphonates clinically relevant?

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 28 KB

english, 2008

129

PL9.4. Protecting the normal skeleton – who, when and why

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 28 KB

english, 2008

130

Editorial board

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 88 KB

english, 2008

131

P76. Physiotherapy in metastatic tumors of humerus: A report of three cases

Ali Reza Jamshidi Fard, Hosain Ali Hadi, Kamran Moshfeghi

Journal:

Cancer Treatment Reviews

Year:

2008

Language:

english

File:

PDF, 29 KB

english, 2008

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