Volume 83; Issue 2

Chemical Biology & Drug Design

Volume 83; Issue 2

1

Discovery of HIV-1 Integrase Inhibitors: Pharmacophore Mapping, Virtual Screening, Molecular Docking, Synthesis, and Biological Evaluation

Bhatt, Hardik, Patel, Paresh, Pannecouque, Christophe

Journal:

Chemical Biology & Drug Design

Year:

2014

Language:

english

File:

PDF, 614 KB

english, 2014

2

Discovering Isozyme-Selective Inhibitor Scaffolds of Human Carbonic Anhydrases Using Structural Alignment and De novo Drug Design Approaches

Xiang, Fu, Xiang, Jun, Fang, Yuanping, Zhang, Mingju, Li, Maoteng

Journal:

Chemical Biology & Drug Design

Year:

2014

Language:

english

File:

PDF, 1.36 MB

english, 2014

3

Exploring the Ligand Recognition Properties of the Human Vasopressin V1a Receptor Using QSAR and Molecular Modeling Studies

Contreras-Romo, Martha C., Martínez-Archundia, Marlet, Deeb, Omar, Ślusarz, Magdalena J., Ramírez-Salinas, Gema, Garduño-Juárez, Ramón, Quintanar-Stephano, Andrés, Ramírez-Galicia, Guillermo, Correa-B

Journal:

Chemical Biology & Drug Design

Year:

2014

Language:

english

File:

PDF, 2.03 MB

english, 2014

4

Screening of Drug Target Proteins by 2D Ligand Matching Approach

Feng, Jianyu, Guo, Hong, Wang, Jian, Lu, Tun

Journal:

Chemical Biology & Drug Design

Year:

2014

Language:

english

File:

PDF, 893 KB

english, 2014

5

1-Thia-4,7-diaza-spiro[4.4]nonane-3,6-dione: A Structural Motif for 5-hydroxytryptamine 6 Receptor Antagonism

Hostetler, Greg, Dunn, Derek, McKenna, Beth A., Kopec, Karla, Chatterjee, Sankar

Journal:

Chemical Biology & Drug Design

Year:

2014

Language:

english

File:

PDF, 469 KB

english, 2014

6

Synthesis and Antimycobacterial Activity of Novel Thiadiazolylhydrazones of 1-Substituted Indole-3-carboxaldehydes

Haj Mohammad Ebrahim Tehrani, Kamaleddin, Mashayekhi, Vida, Azerang, Parisa, Sardari, Soroush, Kobarfard, Farzad, Rostamizadeh, Kobra

Journal:

Chemical Biology & Drug Design

Year:

2014

Language:

english

File:

PDF, 964 KB

english, 2014

7

Synthesis and Evaluation of Chalcone Derivatives as Inhibitors of Neutrophils' Chemotaxis, Phagocytosis and Production of Reactive Oxygen Species

Bukhari, Syed N. A., Tajuddin, Yasmin, Benedict, Vannessa J., Lam, Kok W., Jantan, Ibrahim, Jalil, Juriyati, Jasamai, Malina

Journal:

Chemical Biology & Drug Design

Year:

2014

Language:

english

File:

PDF, 789 KB

english, 2014

8

4-Aminoquinoline- β -Lactam Conjugates: Synthesis, Antimalarial, and Antitubercular Evaluation

Raj, Raghu, Biot, Christophe, Carrère-Kremer, Séverine, Kremer, Laurent, Guérardel, Yann, Gut, Jiri, Rosenthal, Philip J., Kumar, Vipan

Journal:

Chemical Biology & Drug Design

Year:

2014

Language:

english

File:

PDF, 557 KB

english, 2014

9

Mapping of Allosteric Druggable Sites in Activation-Associated Conformers of the M2 Muscarinic Receptor

Miao, Yinglong, Nichols, Sara E., McCammon, J. Andrew

Journal:

Chemical Biology & Drug Design

Year:

2014

Language:

english

File:

PDF, 1.57 MB

english, 2014

10

Synthesis, In Vitro Cytotoxicity and Radiosensitizing Activity of Novel 3-[(2,4-Dinitrophenylamino)Alkyl] Derivatives of 5-Fluorouracil

Khalaj, Ali, Abdi, Khosrou, Ostad, Seyed Nasser, Khoshayand, Mohammad Reza, Lamei, Navid, Nedaie, Hasan Ali

Journal:

Chemical Biology & Drug Design

Year:

2014

Language:

english

File:

PDF, 773 KB

english, 2014

11

X-ray Crystallographic and Fluorometric Analysis of the Interactions of Rhein to Human Serum Albumin

Li, Mei, Lee, Philbert, Zhang, Yao, Ma, ZhiYuan, Yang, Feng, Zhou, ZuPing, Wu, XiaoYang, Liang, Hong

Journal:

Chemical Biology & Drug Design

Year:

2014

Language:

english

File:

PDF, 811 KB

english, 2014

12

Issue Information

Journal:

Chemical Biology & Drug Design

Year:

2014

Language:

english

File:

PDF, 152 KB

english, 2014

13

Crystallographic Fragment-Based Drug Discovery: Use of a Brominated Fragment Library Targeting HIV Protease

Tiefenbrunn, Theresa, Forli, Stefano, Happer, Meaghan, Gonzalez, Ana, Tsai, Yingssu, Soltis, Michael, Elder, John H., Olson, Arthur J., Stout, Charles D.

Journal:

Chemical Biology & Drug Design

Year:

2014

Language:

english

File:

PDF, 740 KB

english, 2014