Volume 10; Issue 5

Chemical Research in Toxicology

Volume 10; Issue 5

1

Mechanisms of Neurotoxicity Associated with Amyloid β Deposition and the Role of Free Radicals in the Pathogenesis of Alzheimer's Disease: A Critical Appraisal

Sayre, Lawrence M., Zagorski, Michael G., Surewicz, Witold K., Krafft, Grant A., Perry, George

Journal:

Chemical Research in Toxicology

Year:

1997

Language:

english

File:

PDF, 143 KB

english, 1997

2

Mechanism-Based Inactivation of Cytochrome P450 2B1 by N -Benzyl-1-aminobenzotriazole

Kent, Ute M., Bend, John R., Chamberlin, Beverly A., Gage, Douglas A., Hollenberg, Paul F.

Journal:

Chemical Research in Toxicology

Year:

1997

Language:

english

File:

PDF, 223 KB

english, 1997

3

Reactive Oxygen-Mediated Protein Oxidation in Aging and Disease

Stadtman, Earl R., Berlett, Barbara S.

Journal:

Chemical Research in Toxicology

Year:

1997

Language:

english

File:

PDF, 291 KB

english, 1997

4

Metabolism of the Cytochrome P450 Mechanism-Based Inhibitor N -Benzyl-1-aminobenzotriazole to Products That Covalently Bind with Protein in Guinea Pig Liver and Lung Microsomes: Comparative Study with 1-Aminobenzotriazole

Woodcroft, Kimberley J., Webb, Chris D., Yao, Ming, Weedon, Alan C., Bend, John R.

Journal:

Chemical Research in Toxicology

Year:

1997

Language:

english

File:

PDF, 551 KB

english, 1997

5

β-Amyloid-Associated Free Radical Oxidative Stress and Neurotoxicity: Implications for Alzheimer's Disease

Butterfield, D. Allan

Journal:

Chemical Research in Toxicology

Year:

1997

Language:

english

File:

PDF, 322 KB

english, 1997

6

Pyridyloxobutyl Adduct O 6 -[4-Oxo-4-(3-pyridyl)butyl]guanine Is Present in 4-(Acetoxymethylnitrosamino)-1-(3-pyridyl)-1-butanone-Treated DNA and Is a Substrate for O 6 -Alkylguanine-DNA Alkyltransferase

Wang, Lijuan, Spratt, Thomas E., Liu, Xiao-Keng, Hecht, Stephen S., Pegg, Anthony E., Peterson, Lisa A.

Journal:

Chemical Research in Toxicology

Year:

1997

Language:

english

File:

PDF, 211 KB

english, 1997

7

Hydrogen Peroxide Supports Human and Rat Cytochrome P450 1A2-Catalyzed 2-Amino-3-methylimidazo[4,5- f ]quinoline Bioactivation to Mutagenic Metabolites: Significance of Cytochrome P450 Peroxygenase

Anari, M. Reza, Josephy, P. David, Henry, Tracey, O'Brien, Peter J.

Journal:

Chemical Research in Toxicology

Year:

1997

Language:

english

File:

PDF, 298 KB

english, 1997

8

Inactivation of the Inducible Nitric Oxide Synthase by Peroxynitrite

Hühmer, Andreas F. R., Nishida, Clinton R., Ortiz de Montellano, Paul R., Schöneich, Christian

Journal:

Chemical Research in Toxicology

Year:

1997

Language:

english

File:

PDF, 323 KB

english, 1997

9

Levuglandin E 2 −Protein Adducts in Human Plasma and Vasculature

Salomon, Robert G., Subbanagounder, Ganesamoorthy, O'Neil, June, Kaur, Kamaljit, Smith, Mark A., Hoff, Henry F., Perry, George, Monnier, Vincent M.

Journal:

Chemical Research in Toxicology

Year:

1997

Language:

english

File:

PDF, 529 KB

english, 1997

10

Temperature-Dependent Formation of a Conjugate between Tris(hydroxymethyl)aminomethane Buffer and the Malondialdehyde−DNA Adduct Pyrimidopurinone

Niedernhofer, Laura J., Riley, Michael, Schnetz-Boutaud, Nathalie, Sanduwaran, Geeganage, Chaudhary, Ajai K., Reddy, G. Ramachandra, Marnett, Lawrence J.

Journal:

Chemical Research in Toxicology

Year:

1997

Language:

english

File:

PDF, 332 KB

english, 1997

11

Role of G→T Transversions in the Mutagenicity of Alkylperoxyl Radicals: Induction of Alkali-Labile Sites in Bacteriophage M13mp19

Harkin, Louise A., Butler, Lisa M., Burcham, Philip C.

Journal:

Chemical Research in Toxicology

Year:

1997

Language:

english

File:

PDF, 193 KB

english, 1997

12

Immunochemical Identification of Mouse Hepatic Protein Adducts Derived from the Nonsteroidal Anti-Inflammatory Drugs Diclofenac, Sulindac, and Ibuprofen

Wade, Lara T., Kenna, J. Gerald, Caldwell, John

Journal:

Chemical Research in Toxicology

Year:

1997

Language:

english

File:

PDF, 517 KB

english, 1997

13

Disruption of Brain Cell Ion Homeostasis in Alzheimer's Disease by Oxy Radicals, and Signaling Pathways That Protect Therefrom

Mattson, Mark P., Mark, Robert J., Furukawa, Katsutoshi, Bruce, Annadora J.

Journal:

Chemical Research in Toxicology

Year:

1997

Language:

english

File:

PDF, 281 KB

english, 1997

14

Frameshift Mutagenesis Induced in Escherichia coli after in Vitro Treatment of Double-Stranded DNA with Methylene Blue plus White Light: Evidence for the Involvement of Lesion(s) Other than 8-Oxo-7,8-dihydro-2‘-deoxyguanosine

Wagner, Jérôme, Fuchs, Robert P. P.

Journal:

Chemical Research in Toxicology

Year:

1997

Language:

english

File:

PDF, 227 KB

english, 1997

15

Microprobe X-ray Absorption Spectroscopic Determination of the Oxidation State of Intracellular Chromium following Exposure of V79 Chinese Hamster Lung Cells to Genotoxic Chromium Complexes

Dillon, Carolyn T., Lay, Peter A., Cholewa, Marian, Legge, George J. F., Bonin, Antonio M., Collins, Terrence J., Kostka, Kimberley L., Shea-McCarthy, Grace

Journal:

Chemical Research in Toxicology

Year:

1997

Language:

english

File:

PDF, 71 KB

english, 1997

16

Role of Cytochrome P450 Enzyme Induction in the Metabolic Activation of Benzo[ c ]phenanthrene in Human Cell Lines and Mouse Epidermis

Einolf, Heidi J., Story, William T., Marcus, Craig B., Larsen, Michele C., Jefcoate, Colin R., Greenlee, William F., Yagi, Haruhiko, Jerina, Donald M., Amin, Shantu, Park, Sang S., Gelboin, Harry V.,

Journal:

Chemical Research in Toxicology

Year:

1997

Language:

english

File:

PDF, 389 KB

english, 1997

17

Nitric Oxide and Derived Species as Toxic Agents in Stroke, AIDS Dementia, and Chronic Neurodegenerative Disorders

Hensley, Kenneth, Tabatabaie, Tahereh, Stewart, Charles A., Pye, Quentin, Floyd, Robert A.

Journal:

Chemical Research in Toxicology

Year:

1997

Language:

english

File:

PDF, 211 KB

english, 1997

18

Free Radical Mechanisms of Neurotoxicity

Journal:

Chemical Research in Toxicology

Year:

1997

Language:

english

File:

PDF, 35 KB

english, 1997