Volume 16; Issue 10

Chemical Research in Toxicology

Volume 16; Issue 10

1

Study of 202 Natural, Synthetic, and Environmental Chemicals for Binding to the Androgen Receptor

Fang, Hong, Tong, Weida, Branham, William S., Moland, Carrie L., Dial, Stacy L., Hong, Huixiao, Xie, Qian, Perkins, Roger, Owens, William, Sheehan, Daniel M.

Journal:

Chemical Research in Toxicology

Year:

2003

Language:

english

File:

PDF, 497 KB

english, 2003

2

3D-MEDNEs: An Alternative “In Silico” Technique for Chemical Research in Toxicology. 1. Prediction of Chemically Induced Agranulocytosis

Díaz, Humberto González, Marrero, Yovani, Hernández, Ivan, Bastida, Iyusmila, Tenorio, Esvieta, Nasco, Oslay, Uriarte, Eugenio, Castañedo, Nilo, Cabrera, Miguel A., Aguila, Edisleidy, Marrero, Osmani,

Journal:

Chemical Research in Toxicology

Year:

2003

Language:

english

File:

PDF, 221 KB

english, 2003

3

Nitrosation, Nitration, and Autoxidation of the Selective Estrogen Receptor Modulator Raloxifene by Nitric Oxide, Peroxynitrite, and Reactive Nitrogen/Oxygen Species

Toader, Violeta, Xu, Xudong, Nicolescu, Adrian, Yu, Linning, Bolton, Judy L., Thatcher, Gregory R. J.

Journal:

Chemical Research in Toxicology

Year:

2003

Language:

english

File:

PDF, 203 KB

english, 2003

4

Inhibition of Peroxynitrite-Mediated LDL Oxidation by Prenylated Flavonoids: The α,β-Unsaturated Keto Functionality of 2‘-Hydroxychalcones as a Novel Antioxidant Pharmacophore

Stevens, Jan F., Miranda, Cristobal L., Frei, Balz, Buhler, Donald R.

Journal:

Chemical Research in Toxicology

Year:

2003

Language:

english

File:

PDF, 206 KB

english, 2003

5

Computer-Aided Knowledge Generation for Understanding Skin Sensitization Mechanisms: The TOPS-MODE Approach

Estrada, Ernesto, Patlewicz, Grace, Chamberlain, Mark, Basketter, David, Larbey, Sue

Journal:

Chemical Research in Toxicology

Year:

2003

Language:

english

File:

PDF, 393 KB

english, 2003

6

Detoxication Pathways Involving Glutathione and Epoxide Hydrolase in the in Vitro Metabolism of Chloroprene

Munter, Tony, Cottrell, Lisa, Golding, Bernard T., Watson, William P.

Journal:

Chemical Research in Toxicology

Year:

2003

Language:

english

File:

PDF, 192 KB

english, 2003

7

Preferential Metabolic Activation of N -Nitrosopiperidine as Compared to Its Structural Homologue N -Nitrosopyrrolidine by Rat Nasal Mucosal Microsomes

Wong, Hansen L., Murphy, Sharon E., Hecht, Stephen S.

Journal:

Chemical Research in Toxicology

Year:

2003

Language:

english

File:

PDF, 102 KB

english, 2003

8

Bioactivation of Clozapine by Murine Cardiac Tissue in Vivo and in Vitro

Williams, Dominic P., O'Donnell, Charles J. L., Maggs, James L., Leeder, J. Steven, Uetrecht, Jack, Pirmohamed, Munir, Park, B. Kevin

Journal:

Chemical Research in Toxicology

Year:

2003

Language:

english

File:

PDF, 111 KB

english, 2003

9

Probing the Possible Molecular Origin of the Highly Selective Toxicity of Antimalarial Peroxide Qinghaosu (Artemisinin)

Wu, Yikang, Liu, He-Hua

Journal:

Chemical Research in Toxicology

Year:

2003

Language:

english

File:

PDF, 71 KB

english, 2003

10

Structural Basis of Binding and Inhibition of Novel Tarantula Toxins in Mammalian Voltage-Dependent Potassium Channels

Shiau, Yu-Shuan, Huang, Po-Tsang, Liou, Horng-Huei, Liaw, Yen-Chywan, Shiau, Yuh-Yuan, Lou, Kuo-Long

Journal:

Chemical Research in Toxicology

Year:

2003

Language:

english

File:

PDF, 717 KB

english, 2003

11

Formation of Vinylogous Compounds in Model Maillard Reaction Systems

Stadler, Richard H., Verzegnassi, Ludovica, Varga, Natalia, Grigorov, Martin, Studer, Alfred, Riediker, Sonja, Schilter, Benoit

Journal:

Chemical Research in Toxicology

Year:

2003

Language:

english

File:

PDF, 403 KB

english, 2003

12

Identification of DNA Adducts Using HPLC/MS/MS Following In Vitro and In Vivo Experiments with Arylamines and Nitroarenes

Jones, Christopher R., Sabbioni, Gabriele

Journal:

Chemical Research in Toxicology

Year:

2003

Language:

english

File:

PDF, 641 KB

english, 2003

13

The Parkinsonian Neurotoxin 1-Methyl-4-Phenylpyridinium (MPP + ) Mediates Release of l -3,4-Dihydroxyphenylalanine ( l -DOPA) and Inhibition of l -DOPA Decarboxylase in the Rat Striatum: A Microdialysis Study

Foster, Steven B., Wrona, Monika Z., Han, Jilin, Dryhurst, Glenn

Journal:

Chemical Research in Toxicology

Year:

2003

Language:

english

File:

PDF, 225 KB

english, 2003

14

Development of QSARs for Predicting the Joint Effects between Cyanogenic Toxicants and Aldehydes

Lin, Zhifen, Yin, Kedong, Shi, Ping, Wang, Liansheng, Yu, Hongxia

Journal:

Chemical Research in Toxicology

Year:

2003

Language:

english

File:

PDF, 120 KB

english, 2003

15

Structural Differentiation of Diastereomeric Benzo[ghi]fluoranthene Adducts of Deoxyadenosine by Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry and Postsource Decay

Chiarelli, M. Paul, Chang, Hui-Fang, Olsen, Kenneth W., Barbacci, Damon, Cho, Bongsup P.

Journal:

Chemical Research in Toxicology

Year:

2003

Language:

english

File:

PDF, 167 KB

english, 2003

16

Proteomic Characterization of Metabolites, Protein Adducts, and Biliary Proteins in Rats Exposed to 1,1-Dichloroethylene or Diclofenac

Jones, Juliet A., Kaphalia, Lata, Treinen-Moslen, Mary, Liebler, Daniel C.

Journal:

Chemical Research in Toxicology

Year:

2003

Language:

english

File:

PDF, 184 KB

english, 2003

17

1 H NMR Pattern Recognition and 31 P NMR Studies with d -Serine in Rat Urine and Kidney, Time- and Dose-Related Metabolic Effects

Williams, Rebecca E., Jacobsen, Matthew, Lock, Edward A.

Journal:

Chemical Research in Toxicology

Year:

2003

Language:

english

File:

PDF, 565 KB

english, 2003

18

Protein−Protein Interactions Involving DNA Glycosylases

Hang, Bo, Singer, B.

Journal:

Chemical Research in Toxicology

Year:

2003

Language:

english

File:

PDF, 296 KB

english, 2003

19

Synthesis, Properties, and NMR Studies of a C8-Phenylguanine Modified Oligonucleotide that Preferentially Adopts the Z DNA Conformation

Gannett, Peter M., Heavner, Sue, Daft, Jonathan R., Shaughnessy, Kevin H., Epperson, Jon D., Greenbaum, Nancy L.

Journal:

Chemical Research in Toxicology

Year:

2003

Language:

english

File:

PDF, 174 KB

english, 2003

20

DNA Adduct Formation from Acrylamide via Conversion To Glycidamide in Adult and Neonatal Mice

Gamboa da Costa, Gonçalo, Churchwell, Mona I., Hamilton, L. Patrice, Von Tungeln, Linda S., Beland, Frederick A., Marques, M. Matilde, Doerge, Daniel R.

Journal:

Chemical Research in Toxicology

Year:

2003

Language:

english

File:

PDF, 158 KB

english, 2003

21

Reactivity with Tris(hydroxymethyl)aminomethane Confounds Immunodetection of Acrolein-Adducted Proteins

Burcham, Philip C., Fontaine, Frank R., Petersen, Dennis R., Pyke, Simon M.

Journal:

Chemical Research in Toxicology

Year:

2003

Language:

english

File:

PDF, 87 KB

english, 2003

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