Volume 18; Issue 2

Chemical Research in Toxicology

Volume 18; Issue 2

1

A Conjugated Diene Identified as a Prohapten: Contact Allergenic Activity and Chemical Reactivity of Proposed Epoxide Metabolites

Nilsson, Anna-Malin, Bergström, Moa Andresen, Luthman, Kristina, Nilsson, J. Lars G., Karlberg, Ann-Therese

Journal:

Chemical Research in Toxicology

Year:

2005

Language:

english

File:

PDF, 191 KB

english, 2005

2

Peroxidation of Polyunsaturated Fatty Acid Methyl Esters Catalyzed by N-Methyl Benzohydroxamic Acid: A New and Convenient Method for Selective Synthesis of Hydroperoxides and Alcohols

Punta, Carlo, Rector, Christopher L., Porter, Ned A.

Journal:

Chemical Research in Toxicology

Year:

2005

Language:

english

File:

PDF, 147 KB

english, 2005

3

Dynamic Monitoring of Cytotoxicity on Microelectronic Sensors

Xing, James Zan, Zhu, Lijun, Jackson, Jo Ann, Gabos, Stephan, Sun, Xue-Jun, Wang, Xiao-bo, Xu, Xiao

Journal:

Chemical Research in Toxicology

Year:

2005

Language:

english

File:

PDF, 420 KB

english, 2005

4

Photodecomposition of Retinyl Palmitate in Ethanol by UVA LightFormation of Photodecomposition Products, Reactive Oxygen Species, and Lipid Peroxides †

Cherng, Shu-Hui, Xia, Qingsu, Blankenship, Lonnie R., Freeman, James P., Wamer, Wayne G., Howard, Paul C., Fu, Peter P.

Journal:

Chemical Research in Toxicology

Year:

2005

Language:

english

File:

PDF, 371 KB

english, 2005

5

Amino Effect on the Protonation of β-Aminoacrylonitrile

Wu, Hong, Glaser, Rainer

Journal:

Chemical Research in Toxicology

Year:

2005

Language:

english

File:

PDF, 229 KB

english, 2005

6

Bioactivation of the Selective Estrogen Receptor Modulator Acolbifene to Quinone Methides

Liu, Ju, Liu, Hong, van Breemen, Richard B., Thatcher, Gregory R. J., Bolton, Judy L.

Journal:

Chemical Research in Toxicology

Year:

2005

Language:

english

File:

PDF, 224 KB

english, 2005

7

Nuclear Magnetic Resonance Analysis of Indomethacin-Induced Gastric Ulcers

Ramadan, Saadallah, Bonin, Antonio M., Kennedy, Brendan J., Hambley, Trevor W., Lay, Peter A.

Journal:

Chemical Research in Toxicology

Year:

2005

Language:

english

File:

PDF, 185 KB

english, 2005

8

Chlorine Substitution Pattern, Molecular Electronic Properties, and the Nature of the Ligand−Receptor Interaction: Quantitative Property−Activity Relationships of Polychlorinated Dibenzofurans

Hirokawa, Shoji, Imasaka, Tomoko, Imasaka, Totaro

Journal:

Chemical Research in Toxicology

Year:

2005

Language:

english

File:

PDF, 189 KB

english, 2005

9

Ternary Complexes of Gentamicin with Iron and Lipid Catalyze Formation of Reactive Oxygen Species

Lesniak, Wojciech, Pecoraro, Vincent L., Schacht, Jochen

Journal:

Chemical Research in Toxicology

Year:

2005

Language:

english

File:

PDF, 284 KB

english, 2005

10

Quinone Methide Formations in the Cu 2+ -Induced Oxidation of a Diterpenone Catechol and Concurrent Damage on DNA

Zhou, Qibing, Zuniga, Miguel A.

Journal:

Chemical Research in Toxicology

Year:

2005

Language:

english

File:

PDF, 236 KB

english, 2005

11

Selective Haptenation of Cellular or Extracellular Protein by Chemical Allergens: Association with Cytokine Polarization

Hopkins, Josephine E., Naisbitt, Dean J., Kitteringham, Neil R., Dearman, Rebecca J., Kimber, Ian, Park, B. Kevin

Journal:

Chemical Research in Toxicology

Year:

2005

Language:

english

File:

PDF, 315 KB

english, 2005

12

Induction of Cytotoxicity, Aldehydic DNA Lesions, and Poly(ADP-Ribose) Polymerase-1 Activation by Catechol Derivatives of Pentachlorophenol in Calf Thymus DNA and in Human Breast Cancer Cells

Lin, Chia-Hua, Leow, Hong-Tsee, Huang, Shih-Chien, Nakamura, Jun, Swenberg, James A., Lin, Po-Hsiung

Journal:

Chemical Research in Toxicology

Year:

2005

Language:

english

File:

PDF, 216 KB

english, 2005

13

Mispairing of a Site Specific Major Groove (2 S ,3 S )-N 6 -(2,3,4-Trihydroxybutyl)-2‘-deoxyadenosyl DNA Adduct of Butadiene Diol Epoxide with Deoxyguanosine: Formation of a dA(anti)·dG(anti) Pairing Interaction

Scholdberg, Tandace A., Nechev, Lubomir V., Merritt, W. Keither, Harris, Thomas M., Harris, Constance M., Lloyd, R. Stephen, Stone, Michael P.

Journal:

Chemical Research in Toxicology

Year:

2005

Language:

english

File:

PDF, 350 KB

english, 2005

14

Reactions of Benzene Oxide with Thiols Including Glutathione

Henderson, Alistair P., Barnes, Martine L., Bleasdale, Christine, Cameron, Richard, Clegg, William, Heath, Sarah L., Lindstrom, Andrew B., Rappaport, Stephen M., Waidyanatha, Suramya, Watson, William

Journal:

Chemical Research in Toxicology

Year:

2005

Language:

english

File:

PDF, 125 KB

english, 2005

15

Photosensitizing Effect of Some Nonsteroidal Antiinflammatory Drugs on Natural and Artificial Membranes: Dependence on Phospholipid Composition

De Guidi, Guido, Ragusa, Santa, Cambria, Maria T., Belvedere, Alessandra, Catalfo, Alfio, Cambria, Antonio

Journal:

Chemical Research in Toxicology

Year:

2005

Language:

english

File:

PDF, 144 KB

english, 2005

16

Integrated Metabonomic Analysis of the Multiorgan Effects of Hydrazine Toxicity in the Rat

Garrod, Sarah, Bollard, Mary E., Nicholls, Andrew W., Connor, Susan C., Connelly, John, Nicholson, Jeremy K., Holmes, Elaine

Journal:

Chemical Research in Toxicology

Year:

2005

Language:

english

File:

PDF, 659 KB

english, 2005

17

Bioactivation of the Selective Estrogen Receptor Modulator Desmethylated Arzoxifene to Quinoids: 4‘-Fluoro Substitution Prevents Quinoid Formation

Liu, Hong, Liu, Ju, van Breemen, Richard B., Thatcher, Gregory R. J., Bolton, Judy L.

Journal:

Chemical Research in Toxicology

Year:

2005

Language:

english

File:

PDF, 213 KB

english, 2005

18

Classification of the Carcinogenicity of N-Nitroso Compounds Based on Support Vector Machines and Linear Discriminant Analysis

Luan, Feng, Zhang, Ruisheng, Zhao, Chunyan, Yao, Xiaojun, Liu, Mancang, Hu, Zhide, Fan, Botao

Journal:

Chemical Research in Toxicology

Year:

2005

Language:

english

File:

PDF, 168 KB

english, 2005

19

Identification of Aldehyde Oxidase as the Neonicotinoid Nitroreductase

Dick, Ryan A., Kanne, David B., Casida, John E.

Journal:

Chemical Research in Toxicology

Year:

2005

Language:

english

File:

PDF, 126 KB

english, 2005

20

Biological Reactive Intermediates VII: BRIs and Human Health and Disease Westin La Paloma Resort, Tucson, Arizona January 4−7, 2006

Journal:

Chemical Research in Toxicology

Year:

2005

File:

PDF, 18 KB

2005

21

Structure−Toxicity Relationships for the Effects to Tetrahymena pyriformis of Aliphatic, Carbonyl-Containing, α,β-Unsaturated Chemicals

Schultz, T. Wayne, Netzeva, Tatiana I., Roberts, David W., Cronin, Mark T. D.

Journal:

Chemical Research in Toxicology

Year:

2005

Language:

english

File:

PDF, 142 KB

english, 2005

22

Effects of Arsenic and UVB on Normal Human Cultured Keratinocytes: Impact on Apoptosis and Implication on Photocarcinogenesis

Chen, Po-Hung, Lan, Cheng-Che E., Chiou, Min-Hsi, Hsieh, Ming-Chu, Chen, Gwo-Shing

Journal:

Chemical Research in Toxicology

Year:

2005

Language:

english

File:

PDF, 675 KB

english, 2005

23

Monochloroacetic Acid Inhibits Liver Gluconeogenesis by Inactivating Glyceraldehyde-3-phosphate Dehydrogenase

Sakai, Akiko, Shimizu, Hiroyasu, Kono, Koichi, Furuya, Eisuke

Journal:

Chemical Research in Toxicology

Year:

2005

Language:

english

File:

PDF, 106 KB

english, 2005

24

Irreversible Inactivation of Arylamine N-Acetyltransferases in the Presence of N-Hydroxy-4-Acetylaminobiphenyl: A Comparison of Human and Hamster Enzymes

Wang, Haiqing, Wagner, Carston R., Hanna, Patrick E.

Journal:

Chemical Research in Toxicology

Year:

2005

Language:

english

File:

PDF, 433 KB

english, 2005

25

Cytochrome P450 Enzymes as Catalysts of Metabolism of 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone, a Tobacco Specific Carcinogen

Jalas, John R., Hecht, Stephen S., Murphy, Sharon E.

Journal:

Chemical Research in Toxicology

Year:

2005

Language:

english

File:

PDF, 155 KB

english, 2005

26

Kinetics of Nucleotide Incorporation Opposite Polycyclic Aromatic Hydrocarbon−DNA Adducts by Processive Bacteriophage T7 DNA Polymerase

Zang, Hong, Harris, Thomas M., Guengerich, F. Peter

Journal:

Chemical Research in Toxicology

Year:

2005

Language:

english

File:

PDF, 519 KB

english, 2005

27

Structural Characterization of an Etheno-2‘-deoxyguanosine Adduct Modified by Tetrahydrofuran

Loureiro, Ana Paula M., de Arruda Campos, Ivan P., Gomes, Osmar F., Possari, Ediliz P. M., Di Mascio, Paolo, Medeiros, Marisa H. G.

Journal:

Chemical Research in Toxicology

Year:

2005

Language:

english

File:

PDF, 616 KB

english, 2005

28

13th North American ISSX/20th JSSX Meeting October 23−27, 2005Maui, Hawaii

Journal:

Chemical Research in Toxicology

Year:

2005

Language:

english

File:

PDF, 19 KB

english, 2005

29

Detection of a Novel Mutagen, 3,6-Dinitrobenzo[ e ]pyrene, as a Major Contaminant in Surface Soil in Osaka and Aichi Prefectures, Japan

Watanabe, Tetsushi, Hasei, Tomohiro, Takahashi, Tomoyuki, Asanoma, Masaharu, Murahashi, Tsuyoshi, Hirayama, Teruhisa, Wakabayashi, Keiji

Journal:

Chemical Research in Toxicology

Year:

2005

Language:

english

File:

PDF, 184 KB

english, 2005

30

2-Alkylpyrrole Formation from 4,5-Epoxy-2-alkenals

Zamora, Rosario, Hidalgo, Francisco J.

Journal:

Chemical Research in Toxicology

Year:

2005

Language:

english

File:

PDF, 110 KB

english, 2005

31

DNA Adduct of the Mitomycin C Metabolite 2,7-Diaminomitosene Is a Nontoxic and Nonmutagenic DNA Lesion in Vitro and in Vivo

Utzat, Christopher D., Clement, Cristina C., Ramos, Leilani A., Das, Arunangshu, Tomasz, Maria, Basu, Ashis K.

Journal:

Chemical Research in Toxicology

Year:

2005

Language:

english

File:

PDF, 531 KB

english, 2005

32

Effect of a Standardized Complex Mixture Derived from Coal Tar on the Metabolic Activation of Carcinogenic Polycyclic Aromatic Hydrocarbons in Human Cells in Culture

Mahadevan, Brinda, Marston, Charis P., Dashwood, Wan-Mohaiza, Li, Yonghai, Pereira, Clifford, Baird, William M.

Journal:

Chemical Research in Toxicology

Year:

2005

Language:

english

File:

PDF, 172 KB

english, 2005

33

Detection of DNA Damage Derived from a Direct Acting Ethylating Agent Present in Cigarette Smoke by Use of Liquid Chromatography−Tandem Mass Spectrometry

Singh, Rajinder, Kaur, Balvinder, Farmer, Peter B.

Journal:

Chemical Research in Toxicology

Year:

2005

Language:

english

File:

PDF, 201 KB

english, 2005

34

Competing Roles of Cytochrome P450 1A1/1B1 and Aldo−Keto Reductase 1A1 in the Metabolic Activation of (±)-7,8-Dihydroxy-7,8-dihydro-benzo[ a ]pyrene in Human Bronchoalveolar Cell Extracts

Jiang, Hao, Shen, Yu-Min, Quinn, Amy M., Penning, Trevor M.

Journal:

Chemical Research in Toxicology

Year:

2005

Language:

english

File:

PDF, 260 KB

english, 2005

35

Formation of Conjugate Adducts in the Reactions of Malonaldehyde−Acetaldehyde and Malonaldehyde−Formaldehyde with Guanosine

Pluskota-Karwatka, Donata, Le Curieux, Frank, Munter, Tony, Sjöholm, Rainer, Kronberg, Leif

Journal:

Chemical Research in Toxicology

Year:

2005

Language:

english

File:

PDF, 152 KB

english, 2005

36

From Experiment to Theory: Molecular Orbital Parameters to Interpret the Skin Sensitization Potential of 5-Chloro-2-methylisothiazol-3-one and 2-Methylisothiazol-3-one

Aptula, Aynur O., Roberts, David W., Cronin, Mark T. D.

Journal:

Chemical Research in Toxicology

Year:

2005

Language:

english

File:

PDF, 94 KB

english, 2005

37

Demonstration by Real-Time Polymerase Chain Reaction that Cellular DNA Alkylation by Novel Aminoindoline Compounds Affects Expression of the Protooncogene c- myc

Nelson, Stephanie M., Ferguson, Lynnette R., Denny, William A.

Journal:

Chemical Research in Toxicology

Year:

2005

Language:

english

File:

PDF, 754 KB

english, 2005

38

Metabolic Activation of a 1,3-Disubstituted Piperazine Derivative: Evidence for a Novel Ring Contraction to an Imidazoline

Doss, George A., Miller, Randall R., Zhang, Zhoupeng, Teffera, Yohannes, Nargund, Ravi P., Palucki, Brenda, Park, Min K., Tang, Yui S., Evans, David C., Baillie, Thomas A., Stearns, Ralph A.

Journal:

Chemical Research in Toxicology

Year:

2005

Language:

english

File:

PDF, 128 KB

english, 2005

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