Volume 20; Issue 11

Chemical Research in Toxicology

Volume 20; Issue 11

1

Uterine Peroxidase-Catalyzed Formation of Diquinone Methides from the Selective Estrogen Receptor Modulators Raloxifene and Desmethylated Arzoxifene

Liu, Hong, Qin, Zhihui, Thatcher, Gregory R. J., Bolton, Judy L.

Journal:

Chemical Research in Toxicology

Year:

2007

Language:

english

File:

PDF, 272 KB

english, 2007

2

Mechanism of 1, N 2 -Etheno-2′-deoxyguanosine Formation from Epoxyaldehydes †

Petrova, Katya V., Jalluri, Ravikumar S., Kozekov, Ivan D., Rizzo, Carmelo J.

Journal:

Chemical Research in Toxicology

Year:

2007

Language:

english

File:

PDF, 265 KB

english, 2007

3

NADPH-Dependent Covalent Binding of [ 3 H]Paroxetine to Human Liver Microsomes and S-9 Fractions: Identification of an Electrophilic Quinone Metabolite of Paroxetine

Zhao, Sabrina X., Dalvie, Deepak K., Kelly, Joan M., Soglia, John R., Frederick, Kosea S., Smith, Evan B., Obach, R. Scott, Kalgutkar, Amit S.

Journal:

Chemical Research in Toxicology

Year:

2007

Language:

english

File:

PDF, 225 KB

english, 2007

4

Identification of Adducts Formed by Reaction of N -Acetoxy-3,5-dimethylaniline with DNA

Cui, Liang, Sun, Hsiao-Lan, Wishnok, John S., Tannenbaum, Steven R., Skipper, Paul L.

Journal:

Chemical Research in Toxicology

Year:

2007

Language:

english

File:

PDF, 137 KB

english, 2007

5

Structure of the 1, N 2 -Etheno-2′-Deoxyguanosine Adduct in Duplex DNA at pH 8.6 †

Shanmugam, Ganesh, Goodenough, Angela K., Kozekov, Ivan D., Guengerich, F. Peter, Rizzo, Carmelo J., Stone, Michael P.

Journal:

Chemical Research in Toxicology

Year:

2007

Language:

english

File:

PDF, 413 KB

english, 2007

6

γ-Radiolysis and Hydroxyl Radical Produce Interstrand Cross-Links in DNA Involving Thymidine †

Ding, Hui, Greenberg, Marc M.

Journal:

Chemical Research in Toxicology

Year:

2007

Language:

english

File:

PDF, 417 KB

english, 2007

7

Chemical–Biological Fingerprinting: Probing the Properties of DNA Lesions Formed by Peroxynitrite

Delaney, Sarah, Delaney, James C., Essigmann, John M.

Journal:

Chemical Research in Toxicology

Year:

2007

Language:

english

File:

PDF, 1.43 MB

english, 2007

8

Hail to the Editor-in-Chief!

Journal:

Chemical Research in Toxicology

Year:

2007

Language:

english

File:

PDF, 44 KB

english, 2007

9

Hepatic Transcriptional Networks Induced by Exposure to 2,3,7,8-Tetrachlorodibenzo- p -dioxin

Hayes, Kevin R., Zastrow, Gina M., Nukaya, Manabu, Pande, Kalyan, Glover, Ed, Maufort, John P., Liss, Adam L., Liu, Yan, Moran, Susan M., Vollrath, Aaron L., Bradfield, Christopher A.

Journal:

Chemical Research in Toxicology

Year:

2007

Language:

english

File:

PDF, 2.27 MB

english, 2007

10

Peroxynitrite Inactivation of Human Cytochrome P450s 2B6 and 2E1: Heme Modification and Site-Specific Nitrotyrosine Formation †

Lin, Hsia-lien, Myshkin, Eugene, Waskell, Lucy, Hollenberg, Paul F.

Journal:

Chemical Research in Toxicology

Year:

2007

Language:

english

File:

PDF, 1.77 MB

english, 2007

11

Identification of the Peroxidation Products of 13-Hydroxy-γ-linolenate and 15-Hydroxyarachidonate: Mechanistic Studies on the Formation of Leukotriene-like Diols †

Rector, Christopher L., Stec, Donald F., Brash, Alan R., Porter, Ned A.

Journal:

Chemical Research in Toxicology

Year:

2007

Language:

english

File:

PDF, 631 KB

english, 2007

12

Intermolecular Protein Cross-Linking During Acrolein Toxicity: Efficacy of Carbonyl Scavengers as Inhibitors of Heat Shock Protein-90 Cross-Linking in A549 Cells

Burcham, Philip C., Raso, Albert, Thompson, Colin, Tan, Dino

Journal:

Chemical Research in Toxicology

Year:

2007

Language:

english

File:

PDF, 740 KB

english, 2007

13

Incorporation of the Hydrophobic Probe N - t -BOC- l -tyrosine tert -Butyl Ester to Red Blood Cell Membranes To Study Peroxynitrite-Dependent Reactions

Romero, Natalia, Peluffo, Gonzalo, Bartesaghi, Silvina, Zhang, Hao, Joseph, Joy, Kalyanaraman, Balaraman, Radi, Rafael

Journal:

Chemical Research in Toxicology

Year:

2007

Language:

english

File:

PDF, 750 KB

english, 2007

14

Species-Specific, P450- and Sulfotransferase-Mediated Novel Ring Contraction of a Naphthyridine- N -Oxide Compound in Cynomolgus Monkey †

Daniels, J. Scott, Espina, Robert, Cao, Kevin, Yuan, Haodan, Lin, Jianrong, Diamond, Sharon, Johnson, Barry, Rodgers, James, Prakash, Shimoga, Unger, Steve, Christ, David, Miwa, Gerald, Gan, Liang-Sha

Journal:

Chemical Research in Toxicology

Year:

2007

Language:

english

File:

PDF, 196 KB

english, 2007

15

Cyclooxygenase-2-Mediated Metabolism of Arachidonic Acid to 15-Oxo-eicosatetraenoic Acid by Rat Intestinal Epithelial Cells

Hwa Lee, Seon, Rangiah, Kannan, Williams, Michelle V., Wehr, Angela Y., DuBois, Raymond N., Blair, Ian A.

Journal:

Chemical Research in Toxicology

Year:

2007

Language:

english

File:

PDF, 223 KB

english, 2007

16

GC/MS Methods To Quantify the 2-Deoxypentos-4-ulose and 3′-Phosphoglycolate Pathways of 4′ Oxidation of 2-Deoxyribose in DNA: Application to DNA Damage Produced by γ Radiation and Bleomycin

Chen, Bingzi, Zhou, Xinfeng, Taghizadeh, Koli, Chen, Jingyang, Stubbe, JoAnne, Dedon, Peter C.

Journal:

Chemical Research in Toxicology

Year:

2007

Language:

english

File:

PDF, 141 KB

english, 2007

17

Analysis of DNA Adducts Formed in Vivo in Rats and Mice from 1,2-Dibromoethane, 1,2-Dichloroethane, Dibromomethane, and Dichloromethane Using HPLC/Accelerator Mass Spectrometry and Relevance to Risk Estimates †

Watanabe, Kengo, Liberman, Rosa G., Skipper, Paul L., Tannenbaum, Steven R., Guengerich, F. Peter

Journal:

Chemical Research in Toxicology

Year:

2007

Language:

english

File:

PDF, 249 KB

english, 2007

18

Modification of Tubulin Cysteines by Nitric Oxide and Nitroxyl Donors Alters Tubulin Polymerization Activity †

Landino, Lisa M., Koumas, Maria T., Mason, Courtney E., Alston, Jane A.

Journal:

Chemical Research in Toxicology

Year:

2007

Language:

english

File:

PDF, 610 KB

english, 2007

19

Mutagenicity of the 1-Nitropyrene-DNA Adduct N -(Deoxyguanosin-8-yl)-1-aminopyrene in Mammalian Cells

Watt, Danielle L., Utzat, Christopher D., Hilario, Pablo, Basu, Ashis K.

Journal:

Chemical Research in Toxicology

Year:

2007

Language:

english

File:

PDF, 213 KB

english, 2007

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