Volume 20; Issue 3

Chemical Research in Toxicology

Volume 20; Issue 3

1

A Comprehensive Investigation of 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) Metabolism in the Mouse Using a Multivariate Data Analysis Approach

Chen, Chi, Ma, Xiaochao, Malfatti, Michael A., Krausz, Kristopher W., Kimura, Shioko, Felton, James S., Idle, Jeffrey R., Gonzalez, Frank J.

Journal:

Chemical Research in Toxicology

Year:

2007

Language:

english

File:

PDF, 590 KB

english, 2007

2

Abiotic Sulfhydryl Reactivity: A Predictor of Aquatic Toxicity for Carbonyl-Containing α,β-Unsaturated Compounds

Yarbrough, Jason W., Schultz, T. Wayne

Journal:

Chemical Research in Toxicology

Year:

2007

Language:

english

File:

PDF, 90 KB

english, 2007

3

Applying Mechanisms of Chemical Toxicity to Predict Drug Safety

Guengerich, F. Peter, MacDonald, James S.

Journal:

Chemical Research in Toxicology

Year:

2007

Language:

english

File:

PDF, 1.89 MB

english, 2007

4

Electrophilic Reaction of Skin-Sensitizing Sultones. Volume 20, Number 1, January 2007, pp 61−71

Journal:

Chemical Research in Toxicology

Year:

2007

File:

PDF, 5 KB

2007

5

Enniatin Exerts p53-Dependent Cytostatic and p53-Independent Cytotoxic Activities against Human Cancer Cells

Dornetshuber, Rita, Heffeter, Petra, Kamyar, Majid-Reza, Peterbauer, Thomas, Berger, Walter, Lemmens-Gruber, Rosa

Journal:

Chemical Research in Toxicology

Year:

2007

Language:

english

File:

PDF, 604 KB

english, 2007

6

Prediction of in Vivo Potential for Metabolic Activation of Drugs into Chemically Reactive Intermediate: Correlation of in Vitro and in Vivo Generation of Reactive Intermediates and in Vitro Glutathione Conjugate Formation in Rats and Humans

Masubuchi, Noriko, Makino, Chie, Murayama, Nobuyuki

Journal:

Chemical Research in Toxicology

Year:

2007

Language:

english

File:

PDF, 192 KB

english, 2007

7

Identification of 2-Amino-1,7-dimethylimidazo[4,5- g ]quinoxaline: An Abundant Mutagenic Heterocyclic Aromatic Amine Formed in Cooked Beef

Turesky, Robert J., Goodenough, Angela K., Ni, Weijuan, McNaughton, Lynn, LeMaster, David M., Holland, Ricky D., Wu, Rebekah W., Felton, James S.

Journal:

Chemical Research in Toxicology

Year:

2007

Language:

english

File:

PDF, 608 KB

english, 2007

8

Different Mechanisms for Inhibition of Human Cytochromes P450 1A1, 1A2, and 1B1 by Polycyclic Aromatic Inhibitors

Shimada, Tsutomu, Murayama, Norie, Okada, Kazushi, Funae, Yoshihiko, Yamazaki, Hiroshi, Guengerich, F. Peter

Journal:

Chemical Research in Toxicology

Year:

2007

Language:

english

File:

PDF, 245 KB

english, 2007

9

Aldo−Keto Reductase- and Cytochrome P450-Dependent Formation of Benzo[ a ]pyrene-Derived DNA Adducts in Human Bronchoalveolar Cells

Ruan, Qian, Gelhaus, Stacy L., Penning, Trevor M., Harvey, Ronald G., Blair, Ian A.

Journal:

Chemical Research in Toxicology

Year:

2007

Language:

english

File:

PDF, 202 KB

english, 2007

10

Exploration of Mechanisms for the Transformation of 8-Hydroxy Guanine Radical to FAPyG by Density Functional Theory

Munk, Barbara H., Burrows, Cynthia J., Schlegel, H. Bernhard

Journal:

Chemical Research in Toxicology

Year:

2007

Language:

english

File:

PDF, 768 KB

english, 2007

11

Physiologically Based Pharmacokinetic/Pharmacodynamic Model for Acrylamide and Its Metabolites in Mice, Rats, and Humans

Young, John F., Luecke, Richard H., Doerge, Daniel R.

Journal:

Chemical Research in Toxicology

Year:

2007

Language:

english

File:

PDF, 323 KB

english, 2007

12

Peripheral Nerve Protein Expression and Carbonyl Content in N,N -Diethlydithiocarbamate Myelinopathy

Viquez, Olga M., Valentine, Holly L., Friedman, David B., Olson, Sandra J., Valentine, William M.

Journal:

Chemical Research in Toxicology

Year:

2007

Language:

english

File:

PDF, 1.23 MB

english, 2007

13

Metabolites of the Carcinogen 2-Amino-α-carboline Formed in Male Sprague−Dawley Rats in Vivo and in Rat Hepatocyte and Human HepG2 Cell Incubates

Yuan, Zhi-Xin, Jha, Gautam, McGregor, Michael A., King, Roberta S.

Journal:

Chemical Research in Toxicology

Year:

2007

Language:

english

File:

PDF, 290 KB

english, 2007

14

Preliminary Program of the 234th ACS National MeetingAugust 19−23, 2007, Boston, Massachusetts

Journal:

Chemical Research in Toxicology

Year:

2007

Language:

english

File:

PDF, 5 KB

english, 2007

15

Possible Role of Ammonia on the Deposition, Retention, and Absorption of Nicotine in Humans while Smoking †

Seeman, Jeffrey I.

Journal:

Chemical Research in Toxicology

Year:

2007

Language:

english

File:

PDF, 314 KB

english, 2007

16

Stereoisomeric Separation and Toxicity of a New Organophosphorus Insecticide Chloramidophos

Zhou, Shanshan, Lin, Kunde, Yang, Huayun, Li, Ling, Liu, Weiping, Li, Jian

Journal:

Chemical Research in Toxicology

Year:

2007

Language:

english

File:

PDF, 74 KB

english, 2007

17

Investigation of the Reaction of Myosmine with Sodium Nitrite in Vitro and in Rats

Hecht, Stephen S., Han, Shaomei, Kenney, Patrick M. J., Wang, Mingyao, Lindgren, Bruce, Wang, Yong, Lao, Yanbin, Hochalter, J. Bradley, Upadhyaya, Pramod

Journal:

Chemical Research in Toxicology

Year:

2007

Language:

english

File:

PDF, 111 KB

english, 2007

18

Cadmium Induces Ca 2+ -Dependent Necrotic Cell Death through Calpain-Triggered Mitochondrial Depolarization and Reactive Oxygen Species-Mediated Inhibition of Nuclear Factor-κB Activity

Yang, Pei-Ming, Chen, Hung-Chi, Tsai, Jia-Shiuan, Lin, Lih-Yuan

Journal:

Chemical Research in Toxicology

Year:

2007

Language:

english

File:

PDF, 366 KB

english, 2007

19

Conformational Differences of the C8-Deoxyguanosine Adduct of 2-Amino-3-methylimidazo[4,5- f ]quinoline (IQ) within the Nar I Recognition Sequence †

Elmquist, C. Eric, Wang, Feng, Stover, James S., Stone, Michael P., Rizzo, Carmelo J.

Journal:

Chemical Research in Toxicology

Year:

2007

Language:

english

File:

PDF, 220 KB

english, 2007

20

Effects of UVB Radiation on 4-Hydroxy-2- trans -nonenal Metabolism and Toxicity in Human Keratinocytes

Aldini, Giancarlo, Granata, Paola, Marinello, Cristina, Beretta, Giangiacomo, Carini, Marina, Maffei Facino, Roberto

Journal:

Chemical Research in Toxicology

Year:

2007

Language:

english

File:

PDF, 268 KB

english, 2007

21

In Memoriam: Christopher J. Michejda (December 19, 1937−January 9, 2007)

Tarasova, Nadya I., Loeppky, Richard N., Byrd, R. Andrew, Keefer, Larry K.

Journal:

Chemical Research in Toxicology

Year:

2007

Language:

english

File:

PDF, 148 KB

english, 2007

22

A Proteomic Analysis of Bromobenzene Reactive Metabolite Targets in Rat Liver Cytosol in Vivo

Koen, Yakov M., Gogichaeva, Natalia V., Alterman, Michail A., Hanzlik, Robert P.

Journal:

Chemical Research in Toxicology

Year:

2007

Language:

english

File:

PDF, 304 KB

english, 2007

23

Targeted Salmon Gene Array (SalArray): A Toxicogenomic Tool for Gene Expression Profiling of Interactions Between Estrogen and Aryl Hydrocarbon Receptor Signalling Pathways

Mortensen, Anne Skjetne, Arukwe, Augustine

Journal:

Chemical Research in Toxicology

Year:

2007

Language:

english

File:

PDF, 235 KB

english, 2007

24

Mechanism of Aging of Mipafox-Inhibited Butyrylcholinesterase

Kropp, Timothy J., Richardson, Rudy J.

Journal:

Chemical Research in Toxicology

Year:

2007

Language:

english

File:

PDF, 104 KB

english, 2007

25

Iron-Loaded Synthetic Chrysotile: A New Model Solid for Studying the Role of Iron in Asbestos Toxicity

Gazzano, Elena, Turci, Francesco, Foresti, Elisabetta, Putzu, Maria Grazia, Aldieri, Elisabetta, Silvagno, Francesca, Lesci, Isidoro Giorgio, Tomatis, Maura, Riganti, Chiara, Romano, Canzio, Fubini, B

Journal:

Chemical Research in Toxicology

Year:

2007

Language:

english

File:

PDF, 473 KB

english, 2007

26

Metabolism in Vitro and in Vivo of the DNA Base Adduct, M 1 G

Knutson, Charles G., Akingbade, Dapo, Crews, Brenda C., Voehler, Markus, Stec, Donald F., Marnett, Lawrence J.

Journal:

Chemical Research in Toxicology

Year:

2007

Language:

english

File:

PDF, 155 KB

english, 2007

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