Volume 21; Issue 5

Chemical Research in Toxicology

Volume 21; Issue 5

1

Pristine (C60) and Hydroxylated [C60(OH)24] Fullerene Phototoxicity towards HaCaT Keratinocytes: Type I vs Type II Mechanisms

Zhao, Baozhong, He, Yu-Ying, Bilski, Piotr J., Chignell, Colin F.

Journal:

Chemical Research in Toxicology

Year:

2008

Language:

english

File:

PDF, 2.74 MB

english, 2008

2

Enantioselectivity in Zebrafish Embryo Toxicity of the Insecticide Acetofenate

Xu, Chao, Zhao, Meirong, Liu, Weiping, Chen, Shengwen, Gan, Jiangying

Journal:

Chemical Research in Toxicology

Year:

2008

Language:

english

File:

PDF, 1.80 MB

english, 2008

3

Bioactivation of Diclofenac in Vitro and in Vivo : Correlation to Electrochemical Studies

Madsen, Kim G., Skonberg, Christian, Jurva, Ulrik, Cornett, Claus, Hansen, Steen H., Johansen, Tommy N., Olsen, Jørgen

Journal:

Chemical Research in Toxicology

Year:

2008

Language:

english

File:

PDF, 295 KB

english, 2008

4

Measurement of Protein Sulfhydryls in Response to Cellular Oxidative Stress Using Gel Electrophoresis and Multiplexed Fluorescent Imaging Analysis

Spiess, Page C., Morin, Dexter, Jewell, William T., Buckpitt, Alan R.

Journal:

Chemical Research in Toxicology

Year:

2008

Language:

english

File:

PDF, 4.36 MB

english, 2008

5

Mitochondrial DNA Impairment in Nucleoside Reverse Transcriptase Inhibitor-Associated Cardiomyopathy

Kohler, James J., Hosseini, Seyed H., Lewis, William

Journal:

Chemical Research in Toxicology

Year:

2008

Language:

english

File:

PDF, 278 KB

english, 2008

6

Oxidative DNA Damage in XPC -Knockout and Its Wild Mice Treated with Equine Estrogen

Okamoto, Yoshinori, Chou, Pei-Hsin, Kim, Sung Yeon, Suzuki, Naomi, Laxmi, Y. R. Santosh, Okamoto, Kanako, Liu, Xiaoping, Matsuda, Tomonari, Shibutani, Shinya

Journal:

Chemical Research in Toxicology

Year:

2008

Language:

english

File:

PDF, 159 KB

english, 2008

7

In This Issue

Rouzer, Carol A.

Journal:

Chemical Research in Toxicology

Year:

2008

Language:

english

File:

PDF, 314 KB

english, 2008

8

Spotlight

Rouzer, Carol A.

Journal:

Chemical Research in Toxicology

Year:

2008

Language:

english

File:

PDF, 266 KB

english, 2008

9

Quantitative High-Performance Liquid Chromatography−Electrospray Ionization−Tandem Mass Spectrometry Analysis of the Adenine−Guanine Cross-Links of 1,2,3,4-Diepoxybutane in Tissues of Butadiene-Exposed B6C3F1 Mice

Goggin, Melissa, Anderson, Chris, Park, Soobong, Swenberg, James, Walker, Vernon, Tretyakova, Natalia

Journal:

Chemical Research in Toxicology

Year:

2008

Language:

english

File:

PDF, 540 KB

english, 2008

10

Synthesis, Microsome-Mediated Metabolism, and Identification of Major Metabolites of Environmental Pollutant Naphtho[8,1,2- ghi ]chrysene

Sharma, Arun K., Gowdahalli, Krishnegowda, Gimbor, Melissa, Amin, Shantu

Journal:

Chemical Research in Toxicology

Year:

2008

Language:

english

File:

PDF, 450 KB

english, 2008

11

Toxicology Down Under: Past Achievements, Present Realities, and Future Prospects

Burcham, Philip C.

Journal:

Chemical Research in Toxicology

Year:

2008

Language:

english

File:

PDF, 975 KB

english, 2008

12

Hypochlorous Acid Damages Histone Proteins Forming 3-Chlorotyrosine and 3,5-Dichlorotyrosine

Kang, Jr., Joseph I., Neidigh, Jonathan W.

Journal:

Chemical Research in Toxicology

Year:

2008

Language:

english

File:

PDF, 842 KB

english, 2008

13

hERG Potassium Channels and the Structural Basis of Drug-Induced Arrhythmias

Mitcheson, John S.

Journal:

Chemical Research in Toxicology

Year:

2008

Language:

english

File:

PDF, 1.11 MB

english, 2008

14

Cardiotoxic Effects of Antihistamines: From Basics to Clinics (…and Back)

Soldovieri, Maria Virginia, Miceli, Francesco, Taglialatela, Maurizio

Journal:

Chemical Research in Toxicology

Year:

2008

Language:

english

File:

PDF, 90 KB

english, 2008

15

Procainamide, but not N -Acetylprocainamide, Induces Protein Free Radical Formation on Myeloperoxidase: A Potential Mechanism of Agranulocytosis

Siraki, Arno G., Deterding, Leesa J., Bonini, Marcelo G., Jiang, JinJie, Ehrenshaft, Marilyn, Tomer, Kenneth B., Mason, Ronald P.

Journal:

Chemical Research in Toxicology

Year:

2008

Language:

english

File:

PDF, 3.43 MB

english, 2008

16

Cardiotoxicity of Antitumor Drugs †

Menna, Pierantonio, Salvatorelli, Emanuela, Minotti, Giorgio

Journal:

Chemical Research in Toxicology

Year:

2008

Language:

english

File:

PDF, 1.15 MB

english, 2008

17

The Pattern of p53 Mutations Caused by PAH o -Quinones is Driven by 8-oxo-dGuo Formation while the Spectrum of Mutations is Determined by Biological Selection for Dominance

Park, Jong-Heum, Gelhaus, Stacy, Vedantam, Srilakshmi, Oliva, Andrea L., Batra, Abhita, Blair, Ian A., Troxel, Andrea B., Field, Jeffrey, Penning, Trevor M.

Journal:

Chemical Research in Toxicology

Year:

2008

Language:

english

File:

PDF, 4.10 MB

english, 2008

18

Letter to the Editor

Starr, Thomas B., Swenberg, James

Journal:

Chemical Research in Toxicology

Year:

2008

Language:

english

File:

PDF, 48 KB

english, 2008

19

Assessment of the Metabolism and Intrinsic Reactivity of a Novel Catechol Metabolite

Hutzler, J. Matthew, Melton, Roger J., Rumsey, Jeanne M., Thompson, David C., Rock, Dan A., Wienkers, Larry C.

Journal:

Chemical Research in Toxicology

Year:

2008

Language:

english

File:

PDF, 627 KB

english, 2008

20

Molecular Structure and Dynamic Properties of a Sulfonamide Derivative of Glutathione That Is Produced Under Conditions of Oxidative Stress by Hypochlorous Acid

Harwood, D. Tim, Nimmo, Susan L., Kettle, Anthony J., Winterbourn, Christine C., Ashby, Michael T.

Journal:

Chemical Research in Toxicology

Year:

2008

Language:

english

File:

PDF, 1.49 MB

english, 2008

21

Conformational Properties of Equilenin−DNA Adducts: Stereoisomer and Base Effects

Ding, Shuang, Shapiro, Robert, Cai, Yuqin, Geacintov, Nicholas E., Broyde, Suse

Journal:

Chemical Research in Toxicology

Year:

2008

Language:

english

File:

PDF, 5.54 MB

english, 2008

22

Xenobiotic Geometry and Media pH Determine Cytotoxicity through Solubility

Luthe, Gregor, Garcia Boy, Regine, Jacobus, James, Smith, Bryan J., Rahaman, Asif, Robertson, Larry W., Ludewig, Gabriele

Journal:

Chemical Research in Toxicology

Year:

2008

Language:

english

File:

PDF, 2.28 MB

english, 2008

23

Bioactivation of a Dihydropyrazole-1-carboxylic acid-(4-chlorophenyl amide) Scaffold to a Putative p -Chlorophenyl Isocyanate in Rat Liver Microsomes and In Vivo in Rats

Chen, Hao, Zhang, Yanhua, Edmunds, Jeremy, Bigge, Christopher, Mutlib, Abdul

Journal:

Chemical Research in Toxicology

Year:

2008

Language:

english

File:

PDF, 675 KB

english, 2008

24

Comparisons of (±)-Benzo[ a ]pyrene- trans -7,8-Dihydrodiol Activation by Human Cytochrome P450 and Aldo−Keto Reductase Enzymes: Effect of Redox State and Expression Levels

Quinn, Amy M., Penning, Trevor M.

Journal:

Chemical Research in Toxicology

Year:

2008

Language:

english

File:

PDF, 402 KB

english, 2008

25

Dose−Response Relationships for Cancer Incidence Reflect Susceptibility Distributions

Lutz, Werner K., Gaylor, David W.

Journal:

Chemical Research in Toxicology

Year:

2008

Language:

english

File:

PDF, 48 KB

english, 2008

26

Protection Against Aflatoxin B 1 -Induced Cytotoxicity by Expression of the Cloned Aflatoxin B 1 -Aldehyde Reductases Rat AKR7A1 and Human AKR7A3

Bodreddigari, Sridevi, Jones, Laundette Knight, Egner, Patricia A., Sutter, Carrie Hayes, Roebuck, Bill D., Guengerich, F. Peter, Kensler, Thomas W., Sutter, Thomas R.

Journal:

Chemical Research in Toxicology

Year:

2008

Language:

english

File:

PDF, 1.11 MB

english, 2008