Volume 21; Issue 6

Chemical Research in Toxicology

Volume 21; Issue 6

1

Dietary Polyphenols as Topoisomerase II Poisons: B Ring and C Ring Substituents Determine the Mechanism of Enzyme-Mediated DNA Cleavage Enhancement

Bandele, Omari J., Clawson, Sara J., Osheroff, Neil

Journal:

Chemical Research in Toxicology

Year:

2008

Language:

english

File:

PDF, 411 KB

english, 2008

2

Shape Signatures: New Descriptors for Predicting Cardiotoxicity In Silico

Chekmarev, Dmitriy S., Kholodovych, Vladyslav, Balakin, Konstantin V., Ivanenkov, Yan, Ekins, Sean, Welsh, William J.

Journal:

Chemical Research in Toxicology

Year:

2008

Language:

english

File:

PDF, 1.07 MB

english, 2008

3

Understanding the Toxicity of Phenols: Using Quantitative Structure−Activity Relationship and Enthalpy Changes To Discriminate between Possible Mechanisms

Shadnia, Hooman, Wright, James S.

Journal:

Chemical Research in Toxicology

Year:

2008

Language:

english

File:

PDF, 1000 KB

english, 2008

4

In Vitro Cytogenetic Results Supporting a DNA Nonreactive Mechanism for Ochratoxin A, Potentially Relevant for Its Carcinogenicity

Mosesso, Pasquale, Cinelli, Serena, Bellacima, Raffaela, Pepe, Gaetano

Journal:

Chemical Research in Toxicology

Year:

2008

Language:

english

File:

PDF, 4.60 MB

english, 2008

5

Completely Different Effects of Desferrioxamine on Hemin/Nitrite/H 2 O 2 -Induced Bovine Serum Albumin Nitration and Oxidation

Lu, Naihao, Zhang, Mingyi, Li, Hailing, Gao, Zhonghong

Journal:

Chemical Research in Toxicology

Year:

2008

Language:

english

File:

PDF, 1.20 MB

english, 2008

6

Transcriptomic Analysis of Nephrotoxicity Induced by Cephaloridine, a Representative Cephalosporin Antibiotic

Rokushima, Masatomo, Fujisawa, Kae, Furukawa, Naoko, Itoh, Fumio, Yanagimoto, Toru, Fukushima, Ryou, Araki, Akiko, Okada, Manabu, Torii, Mikinori, Kato, Ikuo, Ishizaki, Jun, Omi, Kazuo

Journal:

Chemical Research in Toxicology

Year:

2008

Language:

english

File:

PDF, 5.25 MB

english, 2008

7

Tryptophan Oxidation by Singlet Molecular Oxygen [O 2 ( 1 Δ g )]: Mechanistic Studies Using 18 O-Labeled Hydroperoxides, Mass Spectrometry, and Light Emission Measurements

Ronsein, Graziella E., Oliveira, Mauricio C. B., Miyamoto, Sayuri, Medeiros, Marisa H. G., Di Mascio, Paolo

Journal:

Chemical Research in Toxicology

Year:

2008

Language:

english

File:

PDF, 964 KB

english, 2008

8

Call for Papers

Guengerich, F. Peter

Journal:

Chemical Research in Toxicology

Year:

2008

Language:

english

File:

PDF, 19 KB

english, 2008

9

Efficient Synthesis, Liquid Chromatography Purification, and Tandem Mass Spectrometric Characterization of Estrogen-Modified DNA Bases

Zhang, Qiang, Gross, Michael L.

Journal:

Chemical Research in Toxicology

Year:

2008

Language:

english

File:

PDF, 1.12 MB

english, 2008

10

2,2′,3,3′,6,6′-Hexachlorobiphenyl (PCB 136) Atropisomers Interact Enantioselectively with Hepatic Microsomal Cytochrome P450 Enzymes

Kania-Korwel, Izabela, Hrycay, Eugene G., Bandiera, Stelvio M., Lehmler, Hans-Joachim

Journal:

Chemical Research in Toxicology

Year:

2008

Language:

english

File:

PDF, 620 KB

english, 2008

11

Recognition and Incision of Cr(III) Ligand-Conjugated DNA Adducts by the Nucleotide Excision Repair Proteins UvrABC: Importance of the Cr(III)−Purine Moiety in the Enzymatic Reaction

Arakawa, Hirohumi, Tang, Moon-shong

Journal:

Chemical Research in Toxicology

Year:

2008

Language:

english

File:

PDF, 4.81 MB

english, 2008

12

Mechanisms of Protein Damage Induced by Cysteine Thiyl Radical Formation

Schöneich, Christian

Journal:

Chemical Research in Toxicology

Year:

2008

Language:

english

File:

PDF, 138 KB

english, 2008

13

Monitoring in Vivo Metabolism and Elimination of the Endogenous DNA Adduct, M 1 dG {3-(2-Deoxy-β- d - erythro -pentofuranosyl)pyrimido[1,2-α]purin-10(3 H )-one}, by Accelerator Mass Spectrometry †

Knutson, Charles G., Skipper, Paul L., Liberman, Rosa G., Tannenbaum, Steven R., Marnett, Lawrence J.

Journal:

Chemical Research in Toxicology

Year:

2008

Language:

english

File:

PDF, 683 KB

english, 2008

14

Spotlight

Rouzer, Carol A.

Journal:

Chemical Research in Toxicology

Year:

2008

Language:

english

File:

PDF, 390 KB

english, 2008

15

Increased Mitochondrial Thioredoxin 2 Potentiates N -Ethylmaleimide-Induced Cytotoxicity

Chen, Yan, Go, Young-Mi, Pohl, Jan, Reed, Matthew, Cai, Jiyang, Jones, Dean P.

Journal:

Chemical Research in Toxicology

Year:

2008

Language:

english

File:

PDF, 874 KB

english, 2008

16

Methylated Bismuth, but Not Bismuth Citrate or Bismuth Glutathione, Induces Cyto- and Genotoxic Effects in Human Cells in Vitro

von Recklinghausen, U., Hartmann, L. M., Rabieh, S., Hippler, J., Hirner, A. V., Rettenmeier, A. W., Dopp, E.

Journal:

Chemical Research in Toxicology

Year:

2008

Language:

english

File:

PDF, 1.40 MB

english, 2008

17

Copper Neurotoxicity in Rat Substantia Nigra and Striatum Is Dependent on DT-Diaphorase Inhibition

Díaz-Véliz, Gabriela, Paris, Irmgard, Mora, Sergio, Raisman-Vozari, Rita, Segura-Aguilar, Juan

Journal:

Chemical Research in Toxicology

Year:

2008

Language:

english

File:

PDF, 7.52 MB

english, 2008

18

Protein N -Acylation: H 2 O 2 -Mediated Covalent Modification of Protein by Lipid Peroxidation-Derived Saturated Aldehydes

Ishino, Kousuke, Shibata, Takahiro, Ishii, Takeshi, Liu, Yu-Ting, Toyokuni, Shinya, Zhu, Xiaochun, Sayre, Lawrence M., Uchida, Koji

Journal:

Chemical Research in Toxicology

Year:

2008

Language:

english

File:

PDF, 3.07 MB

english, 2008

19

In This Issue

Journal:

Chemical Research in Toxicology

Year:

2008

Language:

english

File:

PDF, 79 KB

english, 2008

20

Examination of Hypochlorous Acid-Induced Damage to Cytosine Residues in a CpG Dinucleotide in DNA

Kang, Joseph I., Sowers, Lawrence C.

Journal:

Chemical Research in Toxicology

Year:

2008

Language:

english

File:

PDF, 721 KB

english, 2008

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