Volume 21; Issue 9

Chemical Research in Toxicology

Volume 21; Issue 9

1

Copper Oxide Nanoparticles Are Highly Toxic: A Comparison between Metal Oxide Nanoparticles and Carbon Nanotubes

Karlsson, Hanna L., Cronholm, Pontus, Gustafsson, Johanna, Möller, Lennart

Journal:

Chemical Research in Toxicology

Year:

2008

Language:

english

File:

PDF, 2.90 MB

english, 2008

2

Structural Defects Play a Major Role in the Acute Lung Toxicity of Multiwall Carbon Nanotubes: Toxicological Aspects

Muller, Julie, Huaux, François, Fonseca, Antonio, Nagy, Janos B., Moreau, Nicolas, Delos, Monique, Raymundo-Piñero, Encarnacion, Béguin, François, Kirsch-Volders, Micheline, Fenoglio, Ivana

Journal:

Chemical Research in Toxicology

Year:

2008

Language:

english

File:

PDF, 7.84 MB

english, 2008

3

Structural Defects Play a Major Role in the Acute Lung Toxicity of Multiwall Carbon Nanotubes: Physicochemical Aspects

Fenoglio, Ivana, Greco, Giovanna, Tomatis, Maura, Muller, Julie, Raymundo-Piñero, Encarnacion, Béguin, François, Fonseca, Antonio, Nagy, Janos B., Lison, Dominique, Fubini, Bice

Journal:

Chemical Research in Toxicology

Year:

2008

Language:

english

File:

PDF, 318 KB

english, 2008

4

Identification and Characterization of Thiosemicarbazones with Antifungal and Antitumor Effects: Cellular Iron Chelation Mediating Cytotoxic Activity

Opletalová, Veronika, Kalinowski, Danuta S., Vejsová, Marcela, Kuneš, Jiří, Pour, Milan, Jampílek, Josef, Buchta, Vladimír, Richardson, Des R.

Journal:

Chemical Research in Toxicology

Year:

2008

Language:

english

File:

PDF, 288 KB

english, 2008

5

Cytotoxicity of Titanium Dioxide Nanoparticles in Mouse Fibroblast Cells

Jin, Cheng-Yu, Zhu, Bang-Shang, Wang, Xue-Feng, Lu, Qing-Hua

Journal:

Chemical Research in Toxicology

Year:

2008

Language:

english

File:

PDF, 13.02 MB

english, 2008

6

Role of the Nitro Functionality in the DNA Binding of 3-Nitro-10-methylbenzothiazolo[3,2- a ]quinolinium Chloride

Colón, Iris Gisela, González, Fernando A., Cordero, Marisol, Zayas, Beatriz, Velez, Christian, Cox, Osvaldo, Kumar, Ajay, Alegría, Antonio E.

Journal:

Chemical Research in Toxicology

Year:

2008

Language:

english

File:

PDF, 427 KB

english, 2008

7

Can In Vitro Metabolism-Dependent Covalent Binding Data in Liver Microsomes Distinguish Hepatotoxic from Nonhepatotoxic Drugs? An Analysis of 18 Drugs with Consideration of Intrinsic Clearance and Daily Dose

Obach, R. Scott, Kalgutkar, Amit S., Soglia, John R., Zhao, Sabrina X.

Journal:

Chemical Research in Toxicology

Year:

2008

Language:

english

File:

PDF, 403 KB

english, 2008

8

Formation of DNA−Protein Cross-Links Between γ-Hydroxypropanodeoxyguanosine and EcoRI

VanderVeen, Laurie A., Harris, Thomas M., Jen-Jacobson, Linda, Marnett, Lawrence J.

Journal:

Chemical Research in Toxicology

Year:

2008

Language:

english

File:

PDF, 223 KB

english, 2008

9

Alkyltransferase-Mediated Toxicity of 1,3-Butadiene Diepoxide

Kalapila, Aley G., Loktionova, Natalia A., Pegg, Anthony E.

Journal:

Chemical Research in Toxicology

Year:

2008

Language:

english

File:

PDF, 1.47 MB

english, 2008

10

Aminoacetone, a Putative Endogenous Source of Methylglyoxal, Causes Oxidative Stress and Death to Insulin-Producing RINm5f Cells

Sartori, Adriano, Garay-Malpartida, Humberto M., Forni, Maria F., Schumacher, Robert I., Dutra, Fernando, Sogayar, Mari C., Bechara, Etelvino J. H.

Journal:

Chemical Research in Toxicology

Year:

2008

Language:

english

File:

PDF, 955 KB

english, 2008

11

Dual Actions Involved in Arsenite-Induced Oxidative DNA Damage

Qin, Xu-Jun, Hudson, Laurie G., Liu, Wenlan, Ding, Wei, Cooper, Karen L., Liu, Ke Jian

Journal:

Chemical Research in Toxicology

Year:

2008

Language:

english

File:

PDF, 7.30 MB

english, 2008

12

Differential Enzymatic Reductions Governing the Differential Hypoxia-Selective Cytotoxicities of Phenazine 5,10-Dioxides

Lavaggi, María Laura, Cabrera, Mauricio, González, Mercedes, Cerecetto, Hugo

Journal:

Chemical Research in Toxicology

Year:

2008

Language:

english

File:

PDF, 400 KB

english, 2008

13

Detection of Multiple Globin Monoadducts and Cross-Links after in Vitro Exposure of Rat Erythrocytes to S -(1,2-Dichlorovinyl)- l -cysteine Sulfoxide and after in Vivo Treatment of Rats with S -(1,2-Dichlorovinyl)- l -cysteine Sulfoxide

Barshteyn, Nella, Elfarra, Adnan A.

Journal:

Chemical Research in Toxicology

Year:

2008

Language:

english

File:

PDF, 377 KB

english, 2008

14

Enantioselective Formation of Ibuprofen- S -Acyl-Glutathione in Vitro in Incubations of Ibuprofen with Rat Hepatocytes †

Grillo, Mark P., Hua, Fengmei

Journal:

Chemical Research in Toxicology

Year:

2008

Language:

english

File:

PDF, 783 KB

english, 2008

15

The Developments and Challenges of Toxicology Education, Research, and Funding in China

Qu, Weidong, Zheng, Weiwei, Zheng, Yuxin

Journal:

Chemical Research in Toxicology

Year:

2008

Language:

english

File:

PDF, 68 KB

english, 2008

16

Determination of Absolute Configurations of 4-Hydroxyequilenin-Cytosine and -Adenine Adducts by Optical Rotatory Dispersion, Electronic Circular Dichroism, Density Functional Theory Calculations, and Mass Spectrometry

Ding, Shuang, Wang, Yan, Kolbanovskiy, Alexander, Durandin, Alexander, Bolton, Judy L., van Breemen, Richard B., Broyde, Suse, Geacintov, Nicholas E.

Journal:

Chemical Research in Toxicology

Year:

2008

Language:

english

File:

PDF, 1.38 MB

english, 2008

17

Correction to The Pattern of p53 Mutations Caused by PAH o -Quinones is Driven by 8-Oxo-dGuo Formation while the Spectrum of Mutations is Determined by Biological Selection for Dominance

Park, Jong-Heum, Gelhaus, Stacy, Vedantam, Srilakshmi, Oliva, Andrea L., Batra, Abhita, Blair, Ian A., Troxel, Andrea B., Field, Jeffrey, Penning, Trevor M.

Journal:

Chemical Research in Toxicology

Year:

2008

Language:

english

File:

PDF, 21 KB

english, 2008

18

UVB-Exposed Chlorinated Bisphenol A Generates Phosphorylated Histone H2AX in Human Skin Cells

Ibuki, Yuko, Tani, Yukinori, Toyooka, Tatsushi

Journal:

Chemical Research in Toxicology

Year:

2008

Language:

english

File:

PDF, 5.51 MB

english, 2008

19

Microprobe XRF Mapping and XAS Investigations of the Intracellular Metabolism of Arsenic for Understanding Arsenic-Induced Toxicity

Munro, Kristie L., Mariana, Anna, Klavins, Andrejs I., Foster, Amalanie J., Lai, Barry, Vogt, Stefan, Cai, ZhongHou, Harris, Hugh H., Dillon, Carolyn T.

Journal:

Chemical Research in Toxicology

Year:

2008

Language:

english

File:

PDF, 7.44 MB

english, 2008

20

Spotlight

Rouzer, Carol A.

Journal:

Chemical Research in Toxicology

Year:

2008

Language:

english

File:

PDF, 251 KB

english, 2008

21

In Vitro Metabolism and Covalent Binding of Enol-Carboxamide Derivatives and Anti-Inflammatory Agents Sudoxicam and Meloxicam: Insights into the Hepatotoxicity of Sudoxicam

Obach, R. Scott, Kalgutkar, Amit S., Ryder, Tim F., Walker, Gregory S.

Journal:

Chemical Research in Toxicology

Year:

2008

Language:

english

File:

PDF, 613 KB

english, 2008

22

The Formamidopyrimidine Derivative of 7-(2-Oxoethyl)-2′-deoxyguanosine

Christov, Plamen P., Kozekov, Ivan D., Rizzo, Carmelo J., Harris, Thomas M.

Journal:

Chemical Research in Toxicology

Year:

2008

Language:

english

File:

PDF, 318 KB

english, 2008

23

Five Tyrosines and Two Serines in Human Albumin Are Labeled by the Organophosphorus Agent FP-Biotin

Ding, Shi-Jian, Carr, John, Carlson, James E., Tong, Larry, Xue, Weihua, Li, Yifeng, Schopfer, Lawrence M., Li, Bin, Nachon, Florian, Asojo, Oluwatoyin, Thompson, Charles M., Hinrichs, Steven H., Mass

Journal:

Chemical Research in Toxicology

Year:

2008

Language:

english

File:

PDF, 1.09 MB

english, 2008

24

Azaspiracid Substituent at C1 Is Relevant to in Vitro Toxicity

Vilariño, Natalia, Nicolaou, K. C., Frederick, Michael O., Cagide, Eva, Alfonso, Carmen, Alonso, Eva, Vieytes, Mercedes R., Botana, Luis M.

Journal:

Chemical Research in Toxicology

Year:

2008

Language:

english

File:

PDF, 9.02 MB

english, 2008

25

Xenobiotic-Activated Receptors: From Transcription to Drug Metabolism to Disease

Journal:

Chemical Research in Toxicology

Year:

2008

Language:

english

File:

PDF, 1.99 MB

english, 2008

26

Demonstration of the Metabolic Pathway Responsible for Nevirapine-Induced Skin Rash

Chen, Jie, Mannargudi, Baskar M., Xu, Ling, Uetrecht, Jack

Journal:

Chemical Research in Toxicology

Year:

2008

Language:

english

File:

PDF, 2.79 MB

english, 2008

27

In this issue

Journal:

Chemical Research in Toxicology

Year:

2008

Language:

english

File:

PDF, 1.08 MB

english, 2008

28

Identification of Plasma Proteins That Are Susceptible to Thiol Oxidation by Hypochlorous Acid and N -Chloramines

Summers, Fiona A., Morgan, Philip E., Davies, Michael J., Hawkins, Clare L.

Journal:

Chemical Research in Toxicology

Year:

2008

Language:

english

File:

PDF, 1.41 MB

english, 2008

29

Application of Stable Isotope-Labeled Compounds in Metabolism and in Metabolism-Mediated Toxicity Studies

Mutlib, Abdul E.

Journal:

Chemical Research in Toxicology

Year:

2008

Language:

english

File:

PDF, 1.05 MB

english, 2008

30

Structure of the 1, N 2 -Ethenodeoxyguanosine Adduct Opposite Cytosine in Duplex DNA: Hoogsteen Base Pairing at pH 5.2 †

Shanmugam, Ganesh, Kozekov, Ivan D., Guengerich, F. Peter, Rizzo, Carmelo J., Stone, Michael P.

Journal:

Chemical Research in Toxicology

Year:

2008

Language:

english

File:

PDF, 9.33 MB

english, 2008