Volume 25; Issue 8

Chemical Research in Toxicology

Volume 25; Issue 8

1

In Vitro Approach to Assess the Potential for Risk of Idiosyncratic Adverse Reactions Caused by Candidate Drugs

Thompson, Richard A., Isin, Emre M., Li, Yan, Weidolf, Lars, Page, Ken, Wilson, Ian, Swallow, Steve, Middleton, Brian, Stahl, Simone, Foster, Alison J., Dolgos, Hugues, Weaver, Richard, Kenna, J. Gerr

Journal:

Chemical Research in Toxicology

Year:

2012

Language:

english

File:

PDF, 551 KB

english, 2012

2

Generation of DNA-Damaging Reactive Oxygen Species via the Autoxidation of Hydrogen Sulfide under Physiologically Relevant Conditions: Chemistry Relevant to Both the Genotoxic and Cell Signaling Properties of H 2 S

Hoffman, Marjorie, Rajapakse, Anuruddha, Shen, Xiulong, Gates, Kent S.

Journal:

Chemical Research in Toxicology

Year:

2012

Language:

english

File:

PDF, 632 KB

english, 2012

3

Dichlorvos Exposure Results in Activation Induced Apoptotic Cell Death in Primary Rat Microglia

Sunkaria, Aditya, Wani, Willayat Yousuf, Sharma, Deep Raj, Gill, Kiran Dip

Journal:

Chemical Research in Toxicology

Year:

2012

Language:

english

File:

PDF, 1.07 MB

english, 2012

4

Selenium Toxicity toward Yeast as Assessed by Microarray Analysis and Deletion Mutant Library Screen: A Role for DNA Repair

Mániková, Dominika, Vlasáková, Danuša, Letavayová, Lucia, Klobučniková, Vlasta, Griač, Peter, Chovanec, Miroslav

Journal:

Chemical Research in Toxicology

Year:

2012

Language:

english

File:

PDF, 1.82 MB

english, 2012

5

Surface Interactions Affect the Toxicity of Engineered Metal Oxide Nanoparticles toward Paramecium

Li, Kungang, Chen, Ying, Zhang, Wen, Pu, Zhichao, Jiang, Lin, Chen, Yongsheng

Journal:

Chemical Research in Toxicology

Year:

2012

Language:

english

File:

PDF, 2.58 MB

english, 2012

6

Meal-Feeding Rodents and Toxicology Research

Carey, Gale B., Merrill, Lisa C.

Journal:

Chemical Research in Toxicology

Year:

2012

Language:

english

File:

PDF, 1.03 MB

english, 2012

7

Review of Chemical and Radiotoxicological Properties of Polonium for Internal Contamination Purposes

Ansoborlo, Eric, Berard, Philippe, Den Auwer, Christophe, Leggett, Rich, Menetrier, Florence, Younes, Ali, Montavon, Gilles, Moisy, Philippe

Journal:

Chemical Research in Toxicology

Year:

2012

Language:

english

File:

PDF, 1.71 MB

english, 2012

8

Identification and Quantification of 1-Hydroxybutene-2-yl Mercapturic Acid in Human Urine by UPLC- HILIC-MS/MS as a Novel Biomarker for 1,3-Butadiene Exposure

Sterz, Katharina, Scherer, Gerhard, Krumsiek, Jan, Theis, Fabian J., Ecker, Josef

Journal:

Chemical Research in Toxicology

Year:

2012

Language:

english

File:

PDF, 278 KB

english, 2012

9

Insect Ryanodine Receptor: Distinct but Coupled Insecticide Binding Sites for [ N -C 3 H 3 ]Chlorantraniliprole, Flubendiamide, and [ 3 H]Ryanodine

Isaacs, André K., Qi, Suzhen, Sarpong, Richmond, Casida, John E.

Journal:

Chemical Research in Toxicology

Year:

2012

Language:

english

File:

PDF, 535 KB

english, 2012

10

Binary and Ternary Binding Affinities between Exonuclease-Deficient Klenow Fragment (Kf-exo – ) and Various Arylamine DNA Lesions Characterized by Surface Plasmon Resonance

Vaidyanathan, V. G., Xu, Lifang, Cho, Bongsup P.

Journal:

Chemical Research in Toxicology

Year:

2012

Language:

english

File:

PDF, 971 KB

english, 2012

11

Pharmacodynamics of Ginsenosides: Antioxidant Activities, Activation of Nrf2, and Potential Synergistic Effects of Combinations

Saw, Constance Lay Lay, Yang, Anne Yuqing, Cheng, David C., Boyanapalli, Sarandeep S.-S., Su, Zheng-Yuan, Khor, Tin Oo, Gao, Song, Wang, Jingrong, Jiang, Zhi-Hong, Kong, Ah-Ng Tony

Journal:

Chemical Research in Toxicology

Year:

2012

Language:

english

File:

PDF, 2.04 MB

english, 2012

12

Reactive Nitrogen Species Reactivities with Nitrones: Theoretical and Experimental Studies

Nash, Kevin M., Rockenbauer, Antal, Villamena, Frederick A.

Journal:

Chemical Research in Toxicology

Year:

2012

Language:

english

File:

PDF, 3.12 MB

english, 2012

13

Cys34 Adducts of Reactive Oxygen Species in Human Serum Albumin

Grigoryan, Hasmik, Li, He, Iavarone, Anthony T., Williams, Evan R., Rappaport, Stephen M.

Journal:

Chemical Research in Toxicology

Year:

2012

Language:

english

File:

PDF, 1.63 MB

english, 2012

14

Replication of the 2,6-Diamino-4-hydroxy- N 5 -(methyl)-formamidopyrimidine (MeFapy-dGuo) Adduct by Eukaryotic DNA Polymerases

Christov, Plamen P., Yamanaka, Kinrin, Choi, Jeong-Yun, Takata, Kei-ichi, Wood, Richard D., Guengerich, F. Peter, Lloyd, R. Stephen, Rizzo, Carmelo J.

Journal:

Chemical Research in Toxicology

Year:

2012

Language:

english

File:

PDF, 1.14 MB

english, 2012

15

Metabolic Impact of 4-Hydroxynonenal on Macrophage-Like RAW 264.7 Function and Activation

Harry, Reese S., Hiatt, Leslie A., Kimmel, Danielle W., Carney, Clare K., Halfpenny, Kristin C., Cliffel, David E., Wright, David W.

Journal:

Chemical Research in Toxicology

Year:

2012

Language:

english

File:

PDF, 2.02 MB

english, 2012

16

Lysosomes as a Possible Target of Enniatin B-Induced Toxicity in Caco-2 Cells

Ivanova, L., Egge-Jacobsen, W. M., Solhaug, A., Thoen, E., Fæste, C. K.

Journal:

Chemical Research in Toxicology

Year:

2012

Language:

english

File:

PDF, 1.77 MB

english, 2012

17

Accurate and Efficient Bypass of 8,5′-Cyclopurine-2′-Deoxynucleosides by Human and Yeast DNA Polymerase η

Swanson, Ashley L., Wang, Jianshuang, Wang, Yinsheng

Journal:

Chemical Research in Toxicology

Year:

2012

Language:

english

File:

PDF, 1.52 MB

english, 2012

18

Bioactivation of Nevirapine to a Reactive Quinone Methide: Implications for Liver Injury

Sharma, Amy M., Li, Yan, Novalen, Maria, Hayes, M. Anthony, Uetrecht, Jack

Journal:

Chemical Research in Toxicology

Year:

2012

Language:

english

File:

PDF, 2.21 MB

english, 2012

19

Effects of N 2 -Alkylguanine, O 6 -Alkylguanine, and Abasic Lesions on DNA Binding and Bypass Synthesis by the Euryarchaeal B-Family DNA Polymerase Vent (exo – )

Lim, Seonhee, Song, Insil, Guengerich, F. Peter, Choi, Jeong-Yun

Journal:

Chemical Research in Toxicology

Year:

2012

Language:

english

File:

PDF, 2.69 MB

english, 2012

20

UVA Photoprotective Properties of an Artificial Carotenylflavonoid Hybrid Molecule

Hundsdörfer, Claas, Stahl, Wilhelm, Müller, Thomas J. J., De Spirt, Silke

Journal:

Chemical Research in Toxicology

Year:

2012

Language:

english

File:

PDF, 1.51 MB

english, 2012

21

Bioactivation of Fluorinated 2-Aryl-benzothiazole Antitumor Molecules by Human Cytochrome P450s 1A1 and 2W1 and Deactivation by Cytochrome P450 2S1

Wang, Kai, Guengerich, F. Peter

Journal:

Chemical Research in Toxicology

Year:

2012

Language:

english

File:

PDF, 1.45 MB

english, 2012

22

Thermodynamic Consequences of the Hyperoxidized Guanine Lesion Guanidinohydantoin in Duplex DNA

Yennie, Craig J., Delaney, Sarah

Journal:

Chemical Research in Toxicology

Year:

2012

Language:

english

File:

PDF, 441 KB

english, 2012

23

Screening for Modulatory Effects on Steroidogenesis Using the Human H295R Adrenocortical Cell Line: A Metabolomics Approach

Rijk, Jeroen C. W., Peijnenburg, Ad A. C. M., Blokland, Marco H., Lommen, Arjen, Hoogenboom, Ron L. A. P., Bovee, Toine F. H.

Journal:

Chemical Research in Toxicology

Year:

2012

Language:

english

File:

PDF, 2.47 MB

english, 2012

24

Mutagenic Bypass of 8-Oxo-7,8-dihydroguanine (8-Hydroxyguanine) by DNA Polymerase κ in Human Cells

Kamiya, Hiroyuki, Kurokawa, Masahiro

Journal:

Chemical Research in Toxicology

Year:

2012

Language:

english

File:

PDF, 377 KB

english, 2012

25

Cresyl Saligenin Phosphate, an Organophosphorus Toxicant, Makes Covalent Adducts with Histidine, Lysine, and Tyrosine Residues of Human Serum Albumin

Liyasova, Mariya S., Schopfer, Lawrence M., Lockridge, Oksana

Journal:

Chemical Research in Toxicology

Year:

2012

Language:

english

File:

PDF, 2.50 MB

english, 2012

26

Correction to Potential of the NBP Method for the Study of Alkylation Mechanisms: NBP as a DNA-Model

Gómez-Bombarelli, Rafael, González-Pérez, Marina, Calle, Emilio, Casado, Julio

Journal:

Chemical Research in Toxicology

Year:

2012

File:

PDF, 103 KB

2012

27

Liver Protein Targets of Hepatotoxic 4-Bromophenol Metabolites

Koen, Yakov M., Hajovsky, Heather, Liu, Ke, Williams, Todd D., Galeva, Nadezhda A., Staudinger, Jeffrey L., Hanzlik, Robert P.

Journal:

Chemical Research in Toxicology

Year:

2012

Language:

english

File:

PDF, 1.57 MB

english, 2012

28

Spotlight

Rouzer, Carol A.

Journal:

Chemical Research in Toxicology

Year:

2012

Language:

english

File:

PDF, 265 KB

english, 2012

29

In This Issue

Journal:

Chemical Research in Toxicology

Year:

2012

Language:

english

File:

PDF, 259 KB

english, 2012

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