Volume 28; Issue 5

Chemical Research in Toxicology

Volume 28; Issue 5

1

DNA Melting and Genotoxicity Induced by Silver Nanoparticles and Graphene

Ivask, Angela, Voelcker, Nicolas H., Seabrook, Shane A., Hor, Maryam, Kirby, Jason K., Fenech, Michael, Davis, Thomas P., Ke, Pu Chun

Journal:

Chemical Research in Toxicology

Year:

2015

Language:

english

File:

PDF, 2.00 MB

english, 2015

2

Aryl Hydrocarbon Receptor Ligand 5F 203 Induces Oxidative Stress That Triggers DNA Damage in Human Breast Cancer Cells

McLean, Lancelot S., Watkins, Cheri N., Campbell, Petreena, Zylstra, Dain, Rowland, Leah, Amis, Louisa H., Scott, Lia, Babb, Crystal E., Livingston, W. Joel, Darwanto, Agus, Davis, Willie L., Senthil,

Journal:

Chemical Research in Toxicology

Year:

2015

Language:

english

File:

PDF, 39.44 MB

english, 2015

3

Molecular Mechanism of Metal-Independent Decomposition of Organic Hydroperoxides by Halogenated Quinoid Carcinogens and the Potential Biological Implications

Huang, Chun-Hua, Ren, Fu-Rong, Shan, Guo-Qiang, Qin, Hao, Mao, Li, Zhu, Ben-Zhan

Journal:

Chemical Research in Toxicology

Year:

2015

Language:

english

File:

PDF, 342 KB

english, 2015

4

Tobacco Alkaloids and Tobacco-Specific Nitrosamines in Dust from Homes of Smokeless Tobacco Users, Active Smokers, and Nontobacco Users

Whitehead, Todd P., Havel, Christopher, Metayer, Catherine, Benowitz, Neal L., Jacob, Peyton

Journal:

Chemical Research in Toxicology

Year:

2015

Language:

english

File:

PDF, 769 KB

english, 2015

5

Catalytic Soman Scavenging by the Y337A/F338A Acetylcholinesterase Mutant Assisted with Novel Site-Directed Aldoximes

Kovarik, Zrinka, Maček Hrvat, Nikolina, Katalinić, Maja, Sit, Rakesh K., Paradyse, Alexander, Žunec, Suzana, Musilek, Kamil, Fokin, Valery V., Taylor, Palmer, Radić, Zoran

Journal:

Chemical Research in Toxicology

Year:

2015

Language:

english

File:

PDF, 1.10 MB

english, 2015

6

UV-Induced DNA Interstrand Cross-Linking and Direct Strand Breaks from a New Type of Binitroimidazole Analogue

Han, Yanyan, Chen, Wenbing, Kuang, Yunyan, Sun, Huabing, Wang, Zhiqiang, Peng, Xiaohua

Journal:

Chemical Research in Toxicology

Year:

2015

Language:

english

File:

PDF, 907 KB

english, 2015

7

Oxidative Transformation of Demethoxy- and Bisdemethoxycurcumin: Products, Mechanism of Formation, and Poisoning of Human Topoisomerase IIα

Gordon, Odaine N., Luis, Paula B., Ashley, Rachel E., Osheroff, Neil, Schneider, Claus

Journal:

Chemical Research in Toxicology

Year:

2015

Language:

english

File:

PDF, 1.30 MB

english, 2015

8

Mitochondrial Carnitine/Acylcarnitine Transporter, a Novel Target of Mercury Toxicity

Tonazzi, Annamaria, Giangregorio, Nicola, Console, Lara, Scalise, Mariafrancesca, La Russa, Daniele, Notaristefano, Caterina, Brunelli, Elvira, Barca, Donatella, Indiveri, Cesare

Journal:

Chemical Research in Toxicology

Year:

2015

Language:

english

File:

PDF, 1.40 MB

english, 2015

9

Prediction of Drug-Induced Liver Injury in HepG2 Cells Cultured with Human Liver Microsomes

Choi, Jong Min, Oh, Soo Jin, Lee, Ji-Yoon, Jeon, Jang Su, Ryu, Chang Seon, Kim, Young-Mi, Lee, Kiho, Kim, Sang Kyum

Journal:

Chemical Research in Toxicology

Year:

2015

Language:

english

File:

PDF, 908 KB

english, 2015

10

(−)-Liriopein B Suppresses Breast Cancer Progression via Inhibition of Multiple Kinases

Wang, Hui-Chun, Chang, Fang-Rong, Huang, Tzu-Jung, Kuo, Ching-Ying, Tsai, Yu-Chi, Wu, Chin-Chung

Journal:

Chemical Research in Toxicology

Year:

2015

Language:

english

File:

PDF, 6.20 MB

english, 2015

11

Simultaneous Detection of 3-Nitrotyrosine and 3-Nitro-4-hydroxyphenylacetic Acid in Human Urine by Online SPE LC-MS/MS and Their Association with Oxidative and Methylated DNA Lesions

Chao, Mu-Rong, Hsu, Yu-Wen, Liu, Hung-Hsin, Lin, Jia-Hong, Hu, Chiung-Wen

Journal:

Chemical Research in Toxicology

Year:

2015

Language:

english

File:

PDF, 1.31 MB

english, 2015

12

Systems Pharmacological Analysis of Drugs Inducing Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis

Hur, Junguk, Zhao, ChunSheng, Bai, Jane P. F.

Journal:

Chemical Research in Toxicology

Year:

2015

Language:

english

File:

PDF, 2.10 MB

english, 2015

13

Steroidomic Footprinting Based on Ultra-High Performance Liquid Chromatography Coupled with Qualitative and Quantitative High-Resolution Mass Spectrometry for the Evaluation of Endocrine Disrupting Chemicals in H295R Cells

Tonoli, David, Fürstenberger, Cornelia, Boccard, Julien, Hochstrasser, Denis, Jeanneret, Fabienne, Odermatt, Alex, Rudaz, Serge

Journal:

Chemical Research in Toxicology

Year:

2015

Language:

english

File:

PDF, 4.43 MB

english, 2015

14

Combined Effects of Cadmium and UVB Radiation on Sea Urchin Embryos: Skeleton Impairment Parallels p38 MAPK Activation and Stress Genes Overexpression

Bonaventura, Rosa, Russo, Roberta, Zito, Francesca, Matranga, Valeria

Journal:

Chemical Research in Toxicology

Year:

2015

Language:

english

File:

PDF, 6.66 MB

english, 2015

15

Reactive Sulfur Species-Mediated Activation of the Keap1–Nrf2 Pathway by 1,2-Naphthoquinone through Sulfenic Acids Formation under Oxidative Stress

Shinkai, Yasuhiro, Abiko, Yumi, Ida, Tomoaki, Miura, Takashi, Kakehashi, Hidenao, Ishii, Isao, Nishida, Motohiro, Sawa, Tomohiro, Akaike, Takaaki, Kumagai, Yoshito

Journal:

Chemical Research in Toxicology

Year:

2015

Language:

english

File:

PDF, 3.15 MB

english, 2015

16

4-Hydroxy-7-oxo-5-heptenoic Acid (HOHA) Lactone is a Biologically Active Precursor for the Generation of 2-(ω-Carboxyethyl)pyrrole (CEP) Derivatives of Proteins and Ethanolamine Phospholipids

Wang, Hua, Linetsky, Mikhail, Guo, Junhong, Choi, Jaewoo, Hong, Li, Chamberlain, Amanda S., Howell, Scott J., Howes, Andrew M., Salomon, Robert G.

Journal:

Chemical Research in Toxicology

Year:

2015

Language:

english

File:

PDF, 4.29 MB

english, 2015

17

Rotenone Stereospecifically Increases ( S )-2-Hydroxyglutarate in SH-SY5Y Neuronal Cells

Worth, Andrew J., Gillespie, Kevin P., Mesaros, Clementina, Guo, Lili, Basu, Sankha S., Snyder, Nathaniel W., Blair, Ian A.

Journal:

Chemical Research in Toxicology

Year:

2015

Language:

english

File:

PDF, 654 KB

english, 2015

18

Mass Spectrometric Characterization of Human Serum Albumin Adducts Formed with N-Oxidized Metabolites of 2-Amino-1-methylphenylimidazo[4,5- b ]pyridine in Human Plasma and Hepatocytes

Wang, Yi, Peng, Lijuan, Bellamri, Medjda, Langouët, Sophie, Turesky, Robert J.

Journal:

Chemical Research in Toxicology

Year:

2015

Language:

english

File:

PDF, 2.58 MB

english, 2015

19

Effects of Diisodecyl Phthalate on PPAR:RXR-Dependent Gene Expression Pathways in Sea Bream Hepatocytes

Cocci, Paolo, Mosconi, Gilberto, Arukwe, Augustine, Mozzicafreddo, Matteo, Angeletti, Mauro, Aretusi, Graziano, Palermo, Francesco Alessandro

Journal:

Chemical Research in Toxicology

Year:

2015

Language:

english

File:

PDF, 4.09 MB

english, 2015

20

Perfluorooctyl Iodide Stimulates Steroidogenesis in H295R Cells via a Cyclic Adenosine Monophosphate Signaling Pathway

Wang, Chang, Ruan, Ting, Liu, Jiyan, He, Bin, Zhou, Qunfang, Jiang, Guibin

Journal:

Chemical Research in Toxicology

Year:

2015

Language:

english

File:

PDF, 876 KB

english, 2015

21

Significantly Different Covalent Binding of Oxidative Metabolites, Acyl Glucuronides, and S-Acyl CoA Conjugates Formed from Xenobiotic Carboxylic Acids in Human Liver Microsomes

Darnell, Malin, Breitholtz, Katarina, Isin, Emre M., Jurva, Ulrik, Weidolf, Lars

Journal:

Chemical Research in Toxicology

Year:

2015

Language:

english

File:

PDF, 2.07 MB

english, 2015

22

Correction to Deoxidation Rates Play a Critical Role in DNA Damage Mediated by Important Synthetic Drugs, Quinoxaline 1,4-Dioxides

Zhang, Huahai, Wang, Xu, Huang, Lingli, Pan, Yuanhu, Li, Juan, Chen, Dongmei, Cheng, Guyue, Hao, Haihong, Tao, Yanfei, Liu, Zhenli, Yuan, Zonghui

Journal:

Chemical Research in Toxicology

Year:

2015

Language:

english

File:

PDF, 115 KB

english, 2015

23

Highly Predictive Reprogramming of tRNA Modifications Is Linked to Selective Expression of Codon-Biased Genes

Chan, Clement T. Y., Deng, Wenjun, Li, Fugen, DeMott, Michael S., Babu, I. Ramesh, Begley, Thomas J., Dedon, Peter C.

Journal:

Chemical Research in Toxicology

Year:

2015

Language:

english

File:

PDF, 2.28 MB

english, 2015

24

Omeprazole Inhibits Pancreatic Cancer Cell Invasion through a Nongenomic Aryl Hydrocarbon Receptor Pathway

Jin, Un-Ho, Kim, Sang-Bae, Safe, Stephen

Journal:

Chemical Research in Toxicology

Year:

2015

Language:

english

File:

PDF, 7.32 MB

english, 2015

25

Spotlight

Shudofsky, Abigail Druck

Journal:

Chemical Research in Toxicology

Year:

2015

Language:

english

File:

PDF, 307 KB

english, 2015