Volume 15; Issue 12

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Chemistry & Biology
Volume 15; Issue 12

Chemistry & Biology

Volume 15; Issue 12

1

Functional Characterization of the Biosynthesis of Radicicol, an Hsp90 Inhibitor Resorcylic Acid Lactone from Chaetomium chiversii

Shuhao Wang, Yuquan Xu, Erin A. Maine, E.M. Kithsiri Wijeratne, Patricia Espinosa-Artiles, A.A. Leslie Gunatilaka, István Molnár

Journal:

Chemistry & Biology

Year:

2008

Language:

english

File:

PDF, 790 KB

english, 2008

2

Known Bioactive Small Molecules Probe the Function of a Widely Conserved but Enigmatic Bacterial ATPase, YjeE

Chand Singh Mangat, Eric David Brown

Journal:

Chemistry & Biology

Year:

2008

Language:

english

File:

PDF, 562 KB

english, 2008

3

Directed Evolution of a Lysosomal Enzyme with Enhanced Activity at Neutral pH by Mammalian Cell-Surface Display

Kai-Chuan Chen, Chia-Hung Wu, Chuan-Yuan Chang, Wei-Cheng Lu, Qingzong Tseng, Zeljko M. Prijovich, Wolfgang Schechinger, Yen-Chywan Liaw, Yu-Lin Leu, Steve R. Roffler

Journal:

Chemistry & Biology

Year:

2008

Language:

english

File:

PDF, 1.10 MB

english, 2008

4

Inhibition and Dispersion of Pseudomonas aeruginosa Biofilms by Glycopeptide Dendrimers Targeting the Fucose-Specific Lectin LecB

Emma M.V. Johansson, Shanika A. Crusz, Elena Kolomiets, Lieven Buts, Rameshwar U. Kadam, Martina Cacciarini, Kai-Malte Bartels, Stephen P. Diggle, Miguel Cámara, Paul Williams, Remy Loris, Cristina Na

Journal:

Chemistry & Biology

Year:

2008

Language:

english

File:

PDF, 1.04 MB

english, 2008

5

In Vitro Reconstituted Biotransformation of 4-Fluorothreonine from Fluoride Ion: Application of the Fluorinase

Hai Deng, Stuart M. Cross, Ryan P. McGlinchey, John T.G. Hamilton, David O'Hagan

Journal:

Chemistry & Biology

Year:

2008

Language:

english

File:

PDF, 697 KB

english, 2008

6

Nitrosothiol Reactivity Profiling Identifies S-Nitrosylated Proteins with Unexpected Stability

Jeremy S. Paige, Guoqiang Xu, Branka Stancevic, Samie R. Jaffrey

Journal:

Chemistry & Biology

Year:

2008

Language:

english

File:

PDF, 901 KB

english, 2008

7

The Importance of Odorant Conformation to the Binding and Activation of a Representative Olfactory Receptor

Zita Peterlin, Yadi Li, Guangxing Sun, Rohan Shah, Stuart Firestein, Kevin Ryan

Journal:

Chemistry & Biology

Year:

2008

Language:

english

File:

PDF, 532 KB

english, 2008

8

Tracing the Silhouette of Individual Cells in S/G2/M Phases with Fluorescence

Asako Sakaue-Sawano, Kenji Ohtawa, Hiroshi Hama, Masako Kawano, Masaharu Ogawa, Atsushi Miyawaki

Journal:

Chemistry & Biology

Year:

2008

Language:

english

File:

PDF, 1.22 MB

english, 2008

9

Supramolecular Iron Cylinder with Unprecedented DNA Binding Is a Potent Cytostatic and Apoptotic Agent without Exhibiting Genotoxicity

Anna C.G. Hotze, Nikolas J. Hodges, Rachel E. Hayden, Carlos Sanchez-Cano, Christopher Paines, Natalia Male, Man-Kit Tse, Chris M. Bunce, J. Kevin Chipman, Michael J. Hannon

Journal:

Chemistry & Biology

Year:

2008

Language:

english

File:

PDF, 983 KB

english, 2008

10

Targeting a Uniquely Nonspecific Prenyl Synthase with Bisphosphonates to Combat Cryptosporidiosis

Jennifer D. Artz, James E. Dunford, Michael J. Arrowood, Aiping Dong, Maksymilian Chruszcz, Kathryn L. Kavanagh, Wladek Minor, R. Graham G. Russell, F. Hal Ebetino, Udo Oppermann, Raymond Hui

Journal:

Chemistry & Biology

Year:

2008

Language:

english

File:

PDF, 1.33 MB

english, 2008

11

Finger Pointing: Engineered Zinc-Finger Proteins Allow Precise Modification and Regulation of Genes

Chandra Shekhar

Journal:

Chemistry & Biology

Year:

2008

Language:

english

File:

PDF, 64 KB

english, 2008

12

In This Issue

Journal:

Chemistry & Biology

Year:

2008

Language:

english

File:

PDF, 716 KB

english, 2008