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Volume 18; Issue 4
Main
Chemistry & Biology
Volume 18; Issue 4
Chemistry & Biology
Volume 18; Issue 4
1
A Small Molecule Binding to the Coactivator CREB-Binding Protein Blocks Apoptosis in Cardiomyocytes
Jagat C. Borah
,
Shiraz Mujtaba
,
Ioannis Karakikes
,
Lei Zeng
,
Michaela Muller
,
Jigneshkumar Patel
,
Natasha Moshkina
,
Keita Morohashi
,
Weijia Zhang
,
Guillermo Gerona-Navarro
,
Roger J. Hajjar
,
Ming-Ming
Journal:
Chemistry & Biology
Year:
2011
Language:
english
File:
PDF, 1.11 MB
Your tags:
english, 2011
2
The Role of Glutathione S-Transferase GliG in Gliotoxin Biosynthesis in Aspergillus fumigatus
Carol Davis
,
Stephen Carberry
,
Markus Schrettl
,
Ishwar Singh
,
John C. Stephens
,
Sarah M. Barry
,
Kevin Kavanagh
,
Gregory L. Challis
,
Dermot Brougham
,
Sean Doyle
Journal:
Chemistry & Biology
Year:
2011
Language:
english
File:
PDF, 833 KB
Your tags:
english, 2011
3
Inhibition of Wnt/β-Catenin Signaling by p38 MAP Kinase Inhibitors Is Explained by Cross-Reactivity with Casein Kinase Iδ/ɛ
Folkert Verkaar
,
Antoon A. van der Doelen
,
Jos F.M. Smits
,
W. Matthijs Blankesteijn
,
Guido J.R. Zaman
Journal:
Chemistry & Biology
Year:
2011
Language:
english
File:
PDF, 1.05 MB
Your tags:
english, 2011
4
Biosynthetic Studies and Genetic Engineering of Pactamycin Analogs with Improved Selectivity toward Malarial Parasites
Wanli Lu
,
Niran Roongsawang
,
Taifo Mahmud
Journal:
Chemistry & Biology
Year:
2011
Language:
english
File:
PDF, 967 KB
Your tags:
english, 2011
5
Characterization of the N-Methyltransferase Activities of the Multifunctional Polypeptide Cyclosporin Synthetase
Tony Velkov
,
James Horne
,
Martin J. Scanlon
,
Ben Capuano
,
Elizabeth Yuriev
,
Alfons Lawen
Journal:
Chemistry & Biology
Year:
2011
Language:
english
File:
PDF, 1.53 MB
Your tags:
english, 2011
6
Small Molecule Antagonists in Distinct Binding Modes Inhibit Drug-Resistant Mutant of Smoothened
Haiyan Tao
,
Qihui Jin
,
Dong-In Koo
,
Xuebin Liao
,
Nathan P. Englund
,
Yan Wang
,
Arun Ramamurthy
,
Peter G. Schultz
,
Marion Dorsch
,
Joseph Kelleher
,
Xu Wu
Journal:
Chemistry & Biology
Year:
2011
Language:
english
File:
PDF, 584 KB
Your tags:
english, 2011
7
Linking Chemistry and Genetics in the Growing Cyanobactin Natural Products Family
Mohamed S. Donia
,
Eric W. Schmidt
Journal:
Chemistry & Biology
Year:
2011
Language:
english
File:
PDF, 1.68 MB
Your tags:
english, 2011
8
Supramolecular Templating in Kirromycin Biosynthesis: The Acyltransferase KirCII Loads Ethylmalonyl-CoA Extender onto a Specific ACP of the trans-AT PKS
Ewa M. Musiol
,
Thomas Härtner
,
Andreas Kulik
,
Jana Moldenhauer
,
Jörn Piel
,
Wolfgang Wohlleben
,
Tilmann Weber
Journal:
Chemistry & Biology
Year:
2011
Language:
english
File:
PDF, 402 KB
Your tags:
english, 2011
9
A Potent and Selective Inhibitor of KIAA1363/AADACL1 that Impairs Prostate Cancer Pathogenesis
Jae Won Chang
,
Daniel K. Nomura
,
Benjamin F. Cravatt
Journal:
Chemistry & Biology
Year:
2011
Language:
english
File:
PDF, 897 KB
Your tags:
english, 2011
10
Real-Time Imaging of Histone H4K12–Specific Acetylation Determines the Modes of Action of Histone Deacetylase and Bromodomain Inhibitors
Tamaki Ito
,
Takashi Umehara
,
Kazuki Sasaki
,
Yoshihiro Nakamura
,
Norikazu Nishino
,
Takaho Terada
,
Mikako Shirouzu
,
Balasundaram Padmanabhan
,
Shigeyuki Yokoyama
,
Akihiro Ito
,
Minoru Yoshida
Journal:
Chemistry & Biology
Year:
2011
Language:
english
File:
PDF, 1.25 MB
Your tags:
english, 2011
11
Rerouting Chlorambucil to Mitochondria Combats Drug Deactivation and Resistance in Cancer Cells
Sonali B. Fonseca
,
Mark P. Pereira
,
Rida Mourtada
,
Marcela Gronda
,
Kristin L. Horton
,
Rose Hurren
,
Mark D. Minden
,
Aaron D. Schimmer
,
Shana O. Kelley
Journal:
Chemistry & Biology
Year:
2011
Language:
english
File:
PDF, 830 KB
Your tags:
english, 2011
12
Sequential Mechanism of Assembly of Multidrug Efflux Pump AcrAB-TolC
Elena B. Tikhonova
,
Yoichi Yamada
,
Helen I. Zgurskaya
Journal:
Chemistry & Biology
Year:
2011
Language:
english
File:
PDF, 1.15 MB
Your tags:
english, 2011
13
Rational Design of an Aryl-C-Glycoside Catalyst from a Natural Product O-Glycosyltransferase
Johannes Härle
,
Stefan Günther
,
Benjamin Lauinger
,
Monika Weber
,
Bernd Kammerer
,
David L. Zechel
,
Andriy Luzhetskyy
,
Andreas Bechthold
Journal:
Chemistry & Biology
Year:
2011
Language:
english
File:
PDF, 1.16 MB
Your tags:
english, 2011
14
Regenerative Chemical Biology: Current Challenges and Future Potential
Ada Ao
,
Jijun Hao
,
Charles C. Hong
Journal:
Chemistry & Biology
Year:
2011
Language:
english
File:
PDF, 790 KB
Your tags:
english, 2011
15
In the Heart of a Dynamic Chromatin
Saadi Khochbin
Journal:
Chemistry & Biology
Year:
2011
Language:
english
File:
PDF, 181 KB
Your tags:
english, 2011
16
Activity-Based Profiling for Drug Discovery
Remigiusz Serwa
,
Edward W. Tate
Journal:
Chemistry & Biology
Year:
2011
Language:
english
File:
PDF, 289 KB
Your tags:
english, 2011
17
A Case of Cross-Reactivity
Hendrik C. Korswagen
Journal:
Chemistry & Biology
Year:
2011
Language:
english
File:
PDF, 68 KB
Your tags:
english, 2011
18
Drug Resistance: A Periplasmic Ménage à Trois
Christine Oswald
,
Klaas M. Pos
Journal:
Chemistry & Biology
Year:
2011
Language:
english
File:
PDF, 425 KB
Your tags:
english, 2011
19
Epizyme: Plying the Epigenome's Enzymes
Alice McCarthy
Journal:
Chemistry & Biology
Year:
2011
Language:
english
File:
PDF, 59 KB
Your tags:
english, 2011
20
In This Issue
Journal:
Chemistry & Biology
Year:
2011
Language:
english
File:
PDF, 271 KB
Your tags:
english, 2011
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