Volume 18; Issue 8

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Chemistry & Biology
Volume 18; Issue 8

Chemistry & Biology

Volume 18; Issue 8

1

A General Framework for Inhibitor Resistance in Protein Kinases

Deborah Balzano, Stefano Santaguida, Andrea Musacchio, Fabrizio Villa

Journal:

Chemistry & Biology

Year:

2011

Language:

english

File:

PDF, 1.65 MB

english, 2011

2

Mechanisms of Osteoclastogenesis Inhibition by a Novel Class of Biphenyl-Type Cannabinoid CB2 Receptor Inverse Agonists

Wolfgang Schuehly, Juan Manuel Viveros Paredes, Jonas Kleyer, Antje Huefner, Sharon Anavi-Goffer, Stefan Raduner, Karl-Heinz Altmann, Jürg Gertsch

Journal:

Chemistry & Biology

Year:

2011

Language:

english

File:

PDF, 1.40 MB

english, 2011

3

A Sensitive and Quantitative Technique for Detecting Autophagic Events Based on Lysosomal Delivery

Hiroyuki Katayama, Takako Kogure, Noboru Mizushima, Tamotsu Yoshimori, Atsushi Miyawaki

Journal:

Chemistry & Biology

Year:

2011

Language:

english

File:

PDF, 1.12 MB

english, 2011

4

Targeting MgrA-Mediated Virulence Regulation in Staphylococcus aureus

Fei Sun, Lu Zhou, Bing-Chuan Zhao, Xin Deng, Hoonsik Cho, Chengqi Yi, Xing Jian, Chun-Xiao Song, Chi-Hao Luan, Taeok Bae, Zigang Li, Chuan He

Journal:

Chemistry & Biology

Year:

2011

Language:

english

File:

PDF, 770 KB

english, 2011

5

Functional Plasticity and Allosteric Regulation of α-Ketoglutarate Decarboxylase in Central Mycobacterial Metabolism

Tristan Wagner, Marco Bellinzoni, Annemarie Wehenkel, Helen M. O'Hare, Pedro M. Alzari

Journal:

Chemistry & Biology

Year:

2011

Language:

english

File:

PDF, 1.08 MB

english, 2011

6

Preferential Uptake of L- versus D-Amino Acid Cell-Penetrating Peptides in a Cell Type-Dependent Manner

Wouter P.R. Verdurmen, Petra H. Bovee-Geurts, Parvesh Wadhwani, Anne S. Ulrich, Mattias Hällbrink, Toin H. van Kuppevelt, Roland Brock

Journal:

Chemistry & Biology

Year:

2011

Language:

english

File:

PDF, 1.42 MB

english, 2011

7

XPF-Dependent DNA Breaks and RNA Polymerase II Arrest Induced by Antitumor DNA Interstrand Crosslinking-Mimetic Alkaloids

Sascha Feuerhahn, Christophe Giraudon, Marta Martínez-Díez, Juan A. Bueren-Calabuig, Carlos M. Galmarini, Federico Gago, Jean-Marc Egly

Journal:

Chemistry & Biology

Year:

2011

Language:

english

File:

PDF, 1.49 MB

english, 2011

8

Novel Proresolving Aspirin-Triggered DHA Pathway

Charles N. Serhan, Gabrielle Fredman, Rong Yang, Sergey Karamnov, Ludmila S. Belayev, Nicolas G. Bazan, Min Zhu, Jeremy W. Winkler, Nicos A. Petasis

Journal:

Chemistry & Biology

Year:

2011

Language:

english

File:

PDF, 1.28 MB

english, 2011

9

Discovery of Kibdelomycin, A Potent New Class of Bacterial Type II Topoisomerase Inhibitor by Chemical-Genetic Profiling in Staphylococcus aureus

John W. Phillips, Michael A. Goetz, Scott K. Smith, Deborah L. Zink, Jon Polishook, Russell Onishi, Scott Salowe, Judyann Wiltsie, John Allocco, Janet Sigmund, Karen Dorso, Suzy Lee, Stephen Skwish, M

Journal:

Chemistry & Biology

Year:

2011

Language:

english

File:

PDF, 837 KB

english, 2011

10

A Nuclear-Localized Fluorescent Hydrogen Peroxide Probe for Monitoring Sirtuin-Mediated Oxidative Stress Responses In Vivo

Bryan C. Dickinson, Yan Tang, Zengyi Chang, Christopher J. Chang

Journal:

Chemistry & Biology

Year:

2011

Language:

english

File:

PDF, 808 KB

english, 2011

11

2′-Fluoro Substituents Can Mimic Native 2′-Hydroxyls within Structured RNA

Marcello Forconi, Jason P. Schwans, Rishi H. Porecha, Raghuvir N. Sengupta, Joseph A. Piccirilli, Daniel Herschlag

Journal:

Chemistry & Biology

Year:

2011

Language:

english

File:

PDF, 382 KB

english, 2011

12

Analysis of the Ketosynthase-Chain Length Factor Heterodimer from the Fredericamycin Polyketide Synthase

Ping-Hui Szu, Sridhar Govindarajan, Michael J. Meehan, Abhirup Das, Don D. Nguyen, Pieter C. Dorrestein, Jeremy Minshull, Chaitan Khosla

Journal:

Chemistry & Biology

Year:

2011

Language:

english

File:

PDF, 1.04 MB

english, 2011

13

A New Fluorescence-Based Assay for Autophagy

Tassula Proikas-Cezanne, Patrice Codogno

Journal:

Chemistry & Biology

Year:

2011

Language:

english

File:

PDF, 146 KB

english, 2011

14

Antibiotic Discovery: A Step in the Right Direction

Arnold L. Demain

Journal:

Chemistry & Biology

Year:

2011

Language:

english

File:

PDF, 46 KB

english, 2011

15

Taking Stock of Telomere Length at Telome Health

Journal:

Chemistry & Biology

Year:

2011

Language:

english

File:

PDF, 66 KB

english, 2011

16

In This Issue

Journal:

Chemistry & Biology

Year:

2011

Language:

english

File:

PDF, 156 KB

english, 2011