Volume 20; Issue 7

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Chemistry & Biology
Volume 20; Issue 7

Chemistry & Biology

Volume 20; Issue 7

1

The Genetic Basis for O-Acetylation of the Microcystin Toxin in Cyanobacteria

Fewer, David P., Wahlsten, Matti, Österholm, Julia, Jokela, Jouni, Rouhiainen, Leo, Kaasalainen, Ulla, Rikkinen, Jouko, Sivonen, Kaarina

Journal:

Chemistry & Biology

Year:

2013

Language:

english

File:

PDF, 1.26 MB

english, 2013

2

Revertants, Low Temperature, and Correctors Reveal the Mechanism of F508del-CFTR Rescue by VX-809 and Suggest Multiple Agents for Full Correction

Farinha, Carlos M., King-Underwood, John, Sousa, Marisa, Correia, Ana Raquel, Henriques, Bárbara J., Roxo-Rosa, Mónica, Da Paula, Ana Carina, Williams, Jonathan, Hirst, Simon, Gomes, Cláudio M., Amara

Journal:

Chemistry & Biology

Year:

2013

Language:

english

File:

PDF, 2.40 MB

english, 2013

3

An Iterative, Bimodular Nonribosomal Peptide Synthetase that Converts Anthranilate and Tryptophan into Tetracyclic Asperlicins

Gao, Xue, Jiang, Wei, Jiménez-Osés, Gonzalo, Choi, Moon Seok, Houk, Kendall N., Tang, Yi, Walsh, Christopher T.

Journal:

Chemistry & Biology

Year:

2013

Language:

english

File:

PDF, 1.33 MB

english, 2013

4

PIKfyve, a Class III PI Kinase, Is the Target of the Small Molecular IL-12/IL-23 Inhibitor Apilimod and a Player in Toll-like Receptor Signaling

Cai, Xinming, Xu, Yongyao, Cheung, Atwood K., Tomlinson, Ronald C., Alcázar-Román, Abel, Murphy, Leon, Billich, Andreas, Zhang, Bailin, Feng, Yan, Klumpp, Martin, Rondeau, Jean-Michel, Fazal, Aleem N.

Journal:

Chemistry & Biology

Year:

2013

Language:

english

File:

PDF, 1.59 MB

english, 2013

5

A Chemical Biology Approach to Interrogate Quorum-Sensing Regulated Behaviors at the Molecular and Cellular Level

Lowery, Colin A., Matamouros, Susana, Niessen, Sherry, Zhu, Jie, Scolnick, Jonathan, Lively, Jenny M., Cravatt, Benjamin F., Miller, Samuel I., Kaufmann, Gunnar F., Janda, Kim D.

Journal:

Chemistry & Biology

Year:

2013

Language:

english

File:

PDF, 850 KB

english, 2013

6

Hereditary Spastic Paraplegia Protein Spartin Is an FK506-Binding Protein Identified by mRNA Display

Tokunaga, Mayuko, Shiheido, Hirokazu, Hayakawa, Ichigo, Utsumi, Akiko, Takashima, Hideaki, Doi, Nobuhide, Horisawa, Kenichi, Sakuma-Yonemura, Yuko, Tabata, Noriko, Yanagawa, Hiroshi

Journal:

Chemistry & Biology

Year:

2013

Language:

english

File:

PDF, 1.18 MB

english, 2013

7

Multimodal Interaction with BCL-2 Family Proteins Underlies the Proapoptotic Activity of PUMA BH3

Edwards, Amanda L., Gavathiotis, Evripidis, LaBelle, James L., Braun, Craig R., Opoku-Nsiah, Kwadwo A., Bird, Gregory H., Walensky, Loren D.

Journal:

Chemistry & Biology

Year:

2013

Language:

english

File:

PDF, 1.79 MB

english, 2013

8

In This Issue

Journal:

Chemistry & Biology

Year:

2013

Language:

english

File:

PDF, 470 KB

english, 2013

9

Addgene: The Bank That Gives Points for (Plasmid) Deposits

Journal:

Chemistry & Biology

Year:

2013

Language:

english

File:

PDF, 83 KB

english, 2013

10

Tandem Modifications of an Epoxyquinone C7N Pharmacophore

Journal:

Chemistry & Biology

Year:

2013

Language:

english

File:

PDF, 259 KB

english, 2013

11

Age-Related Carbonylation of Fibrocartilage Structural Proteins Drives Tissue Degenerative Modification

Scharf, Brian, Clement, Cristina C., Yodmuang, Supansa, Urbanska, Aleksandra M., Suadicani, Sylvia O., Aphkhazava, David, Thi, Mia M., Perino, Giorgio, Hardin, John A., Cobelli, Neil, Vunjak-Novakovic

Journal:

Chemistry & Biology

Year:

2013

Language:

english

File:

PDF, 2.26 MB

english, 2013

12

Tandem Enzymatic Oxygenations in Biosynthesis of Epoxyquinone Pharmacophore of Manumycin-type Metabolites

Rui, Zhe, Sandy, Moriah, Jung, Brian, Zhang, Wenjun

Journal:

Chemistry & Biology

Year:

2013

Language:

english

File:

PDF, 1.29 MB

english, 2013

13

Phenotypic Assays for β-Amyloid in Mouse Embryonic Stem Cell-Derived Neurons

McIntire, Laura Beth J., Landman, Natalie, Kang, Min Suk, Finan, Gina M., Hwang, Jeremy C., Moore, Ann Z., Park, Lydia S., Lin, Chyuan-Sheng, Kim, Tae-Wan

Journal:

Chemistry & Biology

Year:

2013

Language:

english

File:

PDF, 3.38 MB

english, 2013