Volume 21; Issue 11

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Chemistry & Biology
Volume 21; Issue 11

Chemistry & Biology

Volume 21; Issue 11

1

Targeting Bacterial Central Metabolism for Drug Development

Murima, Paul, McKinney, John D., Pethe, Kevin

Journal:

Chemistry & Biology

Year:

2014

Language:

english

File:

PDF, 1.10 MB

english, 2014

2

ATF6 Activation Reduces the Secretion and Extracellular Aggregation of Destabilized Variants of an Amyloidogenic Protein

Chen, John J., Genereux, Joseph C., Qu, Song, Hulleman, John D., Shoulders, Matthew D., Wiseman, R. Luke

Journal:

Chemistry & Biology

Year:

2014

Language:

english

File:

PDF, 2.23 MB

english, 2014

3

Recent Progress in the Design, Study, and Development of c-Jun N-Terminal Kinase Inhibitors as Anticancer Agents

Messoussi, Abdellah, Feneyrolles, Clémence, Bros, Aurélie, Deroide, Arthur, Daydé-Cazals, Bénédicte, Chevé, Gwénaël, Van Hijfte, Nathalie, Fauvel, Bénédicte, Bougrin, Khalid, Yasri, Aziz

Journal:

Chemistry & Biology

Year:

2014

Language:

english

File:

PDF, 1.69 MB

english, 2014

4

Brain Region Mapping Using Global Metabolomics

Ivanisevic, Julijana, Epstein, Adrian A., Kurczy, Michael E., Benton, Paul H., Uritboonthai, Winnie, Fox, Howard S., Boska, Michael D., Gendelman, Howard E., Siuzdak, Gary

Journal:

Chemistry & Biology

Year:

2014

Language:

english

File:

PDF, 2.22 MB

english, 2014

5

A Matter of Location: Influence of G-Quadruplexes on Escherichia coli Gene Expression

Holder, Isabelle T., Hartig, Jörg S.

Journal:

Chemistry & Biology

Year:

2014

Language:

english

File:

PDF, 2.17 MB

english, 2014

6

Chemical Cryptology of Cancer’s Histone Code

Kulkarni, Rhushikesh A., Meier, Jordan L.

Journal:

Chemistry & Biology

Year:

2014

Language:

english

File:

PDF, 430 KB

english, 2014

7

EZH2 Inhibitor Efficacy in Non-Hodgkin’s Lymphoma Does Not Require Suppression of H3K27 Monomethylation

Bradley, William D., Arora, Shilpi, Busby, Jennifer, Balasubramanian, Srividya, Gehling, Victor S., Nasveschuk, Christopher G., Vaswani, Rishi G., Yuan, Chih-Chi, Hatton, Charlie, Zhao, Feng, Williams

Journal:

Chemistry & Biology

Year:

2014

Language:

english

File:

PDF, 3.61 MB

english, 2014

8

Now Playing: Farnesol in the Biofilm

Bell, Stephen A., Chappell, Joseph

Journal:

Chemistry & Biology

Year:

2014

Language:

english

File:

PDF, 330 KB

english, 2014

9

Effects of Pharmacological AMP Deaminase Inhibition and Ampd1 Deletion on Nucleotide Levels and AMPK Activation in Contracting Skeletal Muscle

Plaideau, Catheline, Lai, Yu-Chiang, Kviklyte, Samanta, Zanou, Nadège, Löfgren, Lars, Andersén, Harriet, Vertommen, Didier, Gailly, Philippe, Hue, Louis, Bohlooly-Y, Mohammad, Hallén, Stefan, Rider, M

Journal:

Chemistry & Biology

Year:

2014

Language:

english

File:

PDF, 2.46 MB

english, 2014

10

Inhibition of AMP Deaminase Activity Does Not Improve Glucose Control in Rodent Models of Insulin Resistance or Diabetes

Admyre, Therese, Amrot-Fors, Lena, Andersson, Maria, Bauer, Martin, Bjursell, Mikael, Drmota, Tomas, Hallén, Stefan, Hartleib-Geschwindner, Judith, Lindmark, Bo, Liu, Jianming, Löfgren, Lars, Rohman,

Journal:

Chemistry & Biology

Year:

2014

Language:

english

File:

PDF, 1.33 MB

english, 2014

11

The Membrane-Lytic Peptides K8L9 and Melittin Enter Cancer Cells via Receptor Endocytosis following Subcytotoxic Exposure

Kohno, Masayuki, Horibe, Tomohisa, Ohara, Koji, Ito, Shinji, Kawakami, Koji

Journal:

Chemistry & Biology

Year:

2014

Language:

english

File:

PDF, 1.82 MB

english, 2014

12

Identification of a Potent Antiandrogen that Targets the BF3 Site of the Androgen Receptor and Inhibits Enzalutamide-Resistant Prostate Cancer

Munuganti, Ravi S.N., Hassona, Mohamed D.H., Leblanc, Eric, Frewin, Kate, Singh, Kriti, Ma, Dennis, Ban, Fuqiang, Hsing, Michael, Adomat, Hans, Lallous, Nada, Andre, Christophe, Jonadass, Jon Paul Sel

Journal:

Chemistry & Biology

Year:

2014

Language:

english

File:

PDF, 1.84 MB

english, 2014

13

Intracellular Calcium Levels Determine Differential Modulation of Allosteric Interactions within G Protein-Coupled Receptor Heteromers

Navarro, Gemma, Aguinaga, David, Moreno, Estefania, Hradsky, Johannes, Reddy, Pasham P., Cortés, Antoni, Mallol, Josefa, Casadó, Vicent, Mikhaylova, Marina, Kreutz, Michael R., Lluís, Carme, Canela, E

Journal:

Chemistry & Biology

Year:

2014

Language:

english

File:

PDF, 2.68 MB

english, 2014

14

Two-Allergen Model Reveals Complex Relationship between IgE Crosslinking and Degranulation

Handlogten, Michael W., Deak, Peter E., Bilgicer, Basar

Journal:

Chemistry & Biology

Year:

2014

Language:

english

File:

PDF, 1.71 MB

english, 2014

15

Chemical Targeting of GAPDH Moonlighting Function in Cancer Cells Reveals Its Role in Tubulin Regulation

Jung, Da-Woon, Kim, Woong-Hee, Seo, Shinae, Oh, Eunsang, Yim, Soon-Ho, Ha, Hyung-Ho, Chang, Young-Tae, Williams, Darren Reece

Journal:

Chemistry & Biology

Year:

2014

Language:

english

File:

PDF, 2.59 MB

english, 2014

16

N-Terminal ArgD Peptides from the Classical Staphylococcus aureus Agr System Have Cytotoxic and Proinflammatory Activities

Gonzalez, David J., Corriden, Ross, Akong-Moore, Kathryn, Olson, Joshua, Dorrestein, Pieter C., Nizet, Victor

Journal:

Chemistry & Biology

Year:

2014

Language:

english

File:

PDF, 1.39 MB

english, 2014

17

Artificial Cells, Targeting Obesity, Proteases for Synthetic Biology, and Membrane Lipids in Action

Journal:

Chemistry & Biology

Year:

2014

Language:

english

File:

PDF, 296 KB

english, 2014

18

Structural and Functional Analysis of Bacillus subtilis YisP Reveals a Role of Its Product in Biofilm Production

Feng, Xinxin, Hu, Yumei, Zheng, Yingying, Zhu, Wei, Li, Kai, Huang, Chun-Hsiang, Ko, Tzu-Ping, Ren, Feifei, Chan, Hsiu-Chien, Nega, Mulugeta, Bogue, Shannon, López, Daniel, Kolter, Roberto, Götz, Frie

Journal:

Chemistry & Biology

Year:

2014

Language:

english

File:

PDF, 2.16 MB

english, 2014

19

In This Issue

Journal:

Chemistry & Biology

Year:

2014

Language:

english

File:

PDF, 521 KB

english, 2014

20

PMI: A ΔΨm Independent Pharmacological Regulator of Mitophagy

East, Daniel A., Fagiani, Francesca, Crosby, James, Georgakopoulos, Nikolaos D., Bertrand, Hélène, Schaap, Marjolein, Fowkes, Adrian, Wells, Geoff, Campanella, Michelangelo

Journal:

Chemistry & Biology

Year:

2014

Language:

english

File:

PDF, 2.95 MB

english, 2014

21

Conversion of Substrate Analogs Suggests a Michael Cyclization in Iridoid Biosynthesis

Lindner, Stephanie, Geu-Flores, Fernando, Bräse, Stefan, Sherden, Nathaniel H., O’Connor, Sarah E.

Journal:

Chemistry & Biology

Year:

2014

Language:

english

File:

PDF, 774 KB

english, 2014