Volume 22; Issue 6

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Chemistry & Biology
Volume 22; Issue 6

Chemistry & Biology

Volume 22; Issue 6

1

Inhibition of AMP-Activated Protein Kinase at the Allosteric Drug-Binding Site Promotes Islet Insulin Release

Scott, John W., Galic, Sandra, Graham, Kate L., Foitzik, Richard, Ling, Naomi X.Y., Dite, Toby A., Issa, Samah M.A., Langendorf, Chris G., Weng, Qing Ping, Thomas, Helen E., Kay, Thomas W., Birnberg,

Journal:

Chemistry & Biology

Year:

2015

Language:

english

File:

PDF, 878 KB

english, 2015

2

Iterative Mechanism of Macrodiolide Formation in the Anticancer Compound Conglobatin

Zhou, Yongjun, Murphy, Annabel C., Samborskyy, Markiyan, Prediger, Patricia, Dias, Luiz Carlos, Leadlay, Peter F.

Journal:

Chemistry & Biology

Year:

2015

Language:

english

File:

PDF, 767 KB

english, 2015

3

Overcoming Chemical, Biological, and Computational Challenges in the Development of Inhibitors Targeting Protein-Protein Interactions

Laraia, Luca, McKenzie, Grahame, Spring, David R., Venkitaraman, Ashok R., Huggins, David J.

Journal:

Chemistry & Biology

Year:

2015

Language:

english

File:

PDF, 1.62 MB

english, 2015

4

Dialing in EGFR Signaling

Kennedy, Eileen J., Kannan, Natarajan

Journal:

Chemistry & Biology

Year:

2015

Language:

english

File:

PDF, 822 KB

english, 2015

5

Single Amino Acid Variation Underlies Species-Specific Sensitivity to Amphibian Skin-Derived Opioid-like Peptides

Vardy, Eyal, Sassano, Maria F., Rennekamp, Andrew J., Kroeze, Wesley K., Mosier, Philip D., Westkaemper, Richard B., Stevens, Craig W., Katritch, Vsevolod, Stevens, Raymond C., Peterson, Randall T., R

Journal:

Chemistry & Biology

Year:

2015

Language:

english

File:

PDF, 3.09 MB

english, 2015

6

Cooperation for Better Inhibiting

Novoa, Eva Maria, Ribas de Pouplana, Lluís

Journal:

Chemistry & Biology

Year:

2015

Language:

english

File:

PDF, 368 KB

english, 2015

7

Distinct Substrate Specificity and Catalytic Activity of the Pseudoglycosyltransferase VldE

Abuelizz, Hatem A., Mahmud, Taifo

Journal:

Chemistry & Biology

Year:

2015

Language:

english

File:

PDF, 1.86 MB

english, 2015

8

Hijacking the E3 Ubiquitin Ligase Cereblon to Efficiently Target BRD4

Lu, Jing, Qian, Yimin, Altieri, Martha, Dong, Hanqing, Wang, Jing, Raina, Kanak, Hines, John, Winkler, James D., Crew, Andrew P., Coleman, Kevin, Crews, Craig M.

Journal:

Chemistry & Biology

Year:

2015

Language:

english

File:

PDF, 1.84 MB

english, 2015

9

Nitric Oxide Synthase as a Target for Methicillin-Resistant Staphylococcus aureus

Holden, Jeffrey K., Kang, Soosung, Beasley, Federico C., Cinelli, Maris A., Li, Huiying, Roy, Saurabh G., Dejam, Dillon, Edinger, Aimee L., Nizet, Victor, Silverman, Richard B., Poulos, Thomas L.

Journal:

Chemistry & Biology

Year:

2015

Language:

english

File:

PDF, 1.39 MB

english, 2015

10

Cobalt(III) Protoporphyrin Activates the DGCR8 Protein and Can Compensate microRNA Processing Deficiency

Barr, Ian, Weitz, Sara H., Atkin, Talia, Hsu, PeiKen, Karayiorgou, Maria, Gogos, Joseph A., Weiss, Shimon, Guo, Feng

Journal:

Chemistry & Biology

Year:

2015

Language:

english

File:

PDF, 1.36 MB

english, 2015

11

Dual and Opposite Effects of hRAD51 Chemical Modulation on HIV-1 Integration

Thierry, Sylvain, Benleulmi, Mohamed Salah, Sinzelle, Ludivine, Thierry, Eloise, Calmels, Christina, Chaignepain, Stephane, Waffo-Teguo, Pierre, Merillon, Jean-Michel, Budke, Brian, Pasquet, Jean-Max,

Journal:

Chemistry & Biology

Year:

2015

Language:

english

File:

PDF, 2.64 MB

english, 2015

12

Structural Basis for Specific Inhibition of tRNA Synthetase by an ATP Competitive Inhibitor

Fang, Pengfei, Han, Hongyan, Wang, Jing, Chen, Kaige, Chen, Xin, Guo, Min

Journal:

Chemistry & Biology

Year:

2015

Language:

english

File:

PDF, 3.84 MB

english, 2015

13

In This Issue

Journal:

Chemistry & Biology

Year:

2015

Language:

english

File:

PDF, 401 KB

english, 2015

14

Growth Factor Identity Is Encoded by Discrete Coiled-Coil Rotamers in the EGFR Juxtamembrane Region

Doerner, Amy, Scheck, Rebecca, Schepartz, Alanna

Journal:

Chemistry & Biology

Year:

2015

Language:

english

File:

PDF, 1.82 MB

english, 2015

15

Power of tRNA Fragments, Journey into the Oral Cavity Microbiome, and Controlling TRPV1

Journal:

Chemistry & Biology

Year:

2015

Language:

english

File:

PDF, 433 KB

english, 2015