Volume 1; Issue 9

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ChemMedChem
Volume 1; Issue 9

ChemMedChem

Volume 1; Issue 9

1

Ligand-Based Virtual Screening, Parallel Solution-Phase and Microwave-Assisted Synthesis as Tools to Identify and Synthesize New Inhibitors of Mycobacterium tuberculosis

Fabrizio Manetti, Matteo Magnani, Daniele Castagnolo, Laura Passalacqua, Maurizio Botta, Federico Corelli, Manuela Saddi, Delia Deidda, Alessandro De Logu

Journal:

Year:

2006

Language:

english

File:

PDF, 564 KB

english, 2006

2

Correlation of Biological Activity with Active Site Binding Modes of Geminal Disulfone HIV-1 Integrase Inhibitors

D. Christopher Meadows, Dean J. Tantillo, Jacquelyn Gervay-Hague

Journal:

Year:

2006

Language:

english

File:

PDF, 488 KB

english, 2006

3

Conformationally Constrained CCK8 Analogues Obtained from a Rationally Designed Peptide Library as Ligands for Cholecystokinin Type B Receptor

Stefania De Luca, Michele Saviano, Raffaella Della Moglie, Giuseppe Digilio, Chiara Bracco, Luigi Aloj, Laura Tarallo, Carlo Pedone, Giancarlo Morelli

Journal:

Year:

2006

Language:

english

File:

PDF, 353 KB

english, 2006

4

Use of Triplet Excited States for the Study of Drug Binding to Human and Bovine Serum Albumins

Ignacio Vayá, Carlos J. Bueno, M. Consuelo Jiménez, Miguel A. Miranda

Journal:

Year:

2006

Language:

english

File:

PDF, 131 KB

english, 2006

5

Structure–Activity Relationship Studies on the Immune Stimulatory Effects of Base-Modified CpG Toll-Like Receptor 9 Agonists

Marion Jurk, Andrea Kritzler, Harald Debelak, Jörg Vollmer, Arthur M. Krieg, Eugen Uhlmann

Journal:

Year:

2006

Language:

english

File:

PDF, 365 KB

english, 2006

6

Identification of a Potent Agonist of the Orphan Nuclear Receptor Nurr1

Celine Dubois, Bastian Hengerer, Henri Mattes

Journal:

Year:

2006

Language:

english

File:

PDF, 101 KB

english, 2006

7

Rational Design of Aziridine-Containing Cysteine Protease Inhibitors with Improved Potency: Studies on Inhibition Mechanism

Radim Vicik, Holger Helten, Tanja Schirmeister, Bernd Engels

Journal:

Year:

2006

Language:

english

File:

PDF, 268 KB

english, 2006

8

Determination of the Bound Conformation of a Competitive Nanomolar Inhibitor of Mycobacterium tuberculosis Type II Dehydroquinase by NMR Spectroscopy

Verónica F. V. Prazeres, Cristina Sánchez-Sixto, Luis Castedo, Ángeles Canales, Francisco Javier Cañada, Jesús Jiménez-Barbero, Heather Lamb, Alastair R. Hawkins, Concepción González-Bello

Journal:

Year:

2006

Language:

english

File:

PDF, 492 KB

english, 2006

9

Bis-Tetrahydrofuran: a Privileged Ligand for Darunavir and a New Generation of HIV Protease Inhibitors That Combat Drug Resistance

Arun K. Ghosh, Perali Ramu Sridhar, Nagaswamy Kumaragurubaran, Yasuhiro Koh, Irene T. Weber, Hiroaki Mitsuya

Journal:

Year:

2006

Language:

english

File:

PDF, 280 KB

english, 2006

10

Synthesis and Biological Evaluation of a Multiantigenic Tn/TF-Containing Glycopeptide Mimic of the Tumor-Related MUC1 Glycoprotein

Gaëlle-Anne Cremer, Nicole Bureaud, Véronique Piller, Horst Kunz, Friedrich Piller, Agnès F. Delmas

Journal:

Year:

2006

Language:

english

File:

PDF, 214 KB

english, 2006

11

Probing, Inhibition, and Crystallographic Characterization of Metallo-β-lactamase (IMP-1) with Fluorescent Agents Containing Dansyl and Thiol Groups

Hiromasa Kurosaki, Yoshihiro Yamaguchi, Hisami Yasuzawa, Wanchun Jin, Yuriko Yamagata, Yoshichika Arakawa

Journal:

Year:

2006

Language:

english

File:

PDF, 352 KB

english, 2006

12

Platensimycin, a New Antibiotic and “Superbug Challenger” from Nature

Dieter Häbich, Franz von Nussbaum

Journal:

Year:

2006

Language:

english

File:

PDF, 209 KB

english, 2006

13

Prediction of ADMET Properties

Ulf Norinder, Christel A. S. Bergström

Journal:

Year:

2006

Language:

english

File:

PDF, 653 KB

english, 2006

14

Preview: ChemMedChem 9/2006

Journal:

Year:

2006

File:

PDF, 31 KB

2006

15

Cover Picture: Synthesis and Biological Evaluation of a Multiantigenic Tn/TF-Containing Glycopeptide Mimic of the Tumor-Related MUC1 Glycoprotein (ChemMedChem 9/2006)

Gaëlle-Anne Cremer, Nicole Bureaud, Véronique Piller, Horst Kunz, Friedrich Piller, Agnès F. Delmas

Journal:

Year:

2006

File:

PDF, 37 KB

2006

16

Graphical Abstract: ChemMedChem 9/2006

Journal:

Year:

2006

Language:

english

File:

PDF, 636 KB

english, 2006

17

From our sister journals: ChemMedChem 9/2006

Journal:

Year:

2006

Language:

english

File:

PDF, 244 KB

english, 2006

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