Volume 10; Issue 5

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ChemMedChem
Volume 10; Issue 5

ChemMedChem

Volume 10; Issue 5

1

A Chemical Chaperone-Based Drug Candidate is Effective in a Mouse Model of Amyotrophic Lateral Sclerosis (ALS)

Getter, Tamar, Zaks, Ilana, Barhum, Yael, Ben-Zur, Tali, Böselt, Sebastian, Gregoire, Simpson, Viskind, Olga, Shani, Tom, Gottlieb, Hugo, Green, Omer, Shubely, Moran, Senderowitz, Hanoch, Israelson, A

Journal:

Year:

2015

Language:

english

File:

PDF, 1.76 MB

english, 2015

2

Targeting the Erythrocytic and Liver Stages of Malaria Parasites with s -Triazine-Based Hybrids

Rodrigues, Catarina A. B., Frade, Raquel F. M., Albuquerque, Inês S., Perry, Maria J., Gut, Jiri, Machado, Marta, Rosenthal, Philip J., Prudêncio, Miguel, Afonso, Carlos A. M., Moreira, Rui

Journal:

Year:

2015

Language:

english

File:

PDF, 931 KB

english, 2015

3

Novel 1,4-Substituted-1,2,3-Triazoles as Antitubercular Agents

Altimari, Jarrad M., Hockey, Samantha C., Boshoff, Helena I., Sajid, Andaleeb, Henderson, Luke C.

Journal:

Year:

2015

Language:

english

File:

PDF, 1.90 MB

english, 2015

4

Indolo[3,2- c ]quinoline G-Quadruplex Stabilizers: a Structural Analysis of Binding to the Human Telomeric G-Quadruplex

Lavrado, João, Ohnmacht, Stephan A., Correia, Isabel, Leitão, Clara, Pisco, Sílvia, Gunaratnam, Mekala, Moreira, Rui, Neidle, Stephen, Santos, Daniel J. V. A. dos, Paulo, Alexandra

Journal:

Year:

2015

Language:

english

File:

PDF, 1.11 MB

english, 2015

5

Benzo[ b ]tryptanthrin Inhibits MDR1, Topoisomerase Activity, and Reverses Adriamycin Resistance in Breast Cancer Cells

Jun, Kyu-Yeon, Park, So-Eun, Liang, Jing Lu, Jahng, Yurngdong, Kwon, Youngjoo

Journal:

Year:

2015

Language:

english

File:

PDF, 2.02 MB

english, 2015

6

Bis(benzoyloxybenzyl)-Di PP ro Nucleoside Diphosphates of Anti-HIV Active Nucleoside Analogues

Weinschenk, Lina, Gollnest, Tristan, Schols, Dominique, Balzarini, Jan, Meier, Chris

Journal:

Year:

2015

Language:

english

File:

PDF, 445 KB

english, 2015

7

Development of Urea and Thiourea Kynurenamine Derivatives: Synthesis, Molecular Modeling, and Biological Evaluation as Nitric Oxide Synthase Inhibitors

Chayah, Mariem, Carrión, M. Dora, Gallo, Miguel A., Jiménez, Rosario, Duarte, Juan, Camacho, M. Encarnación

Journal:

Year:

2015

Language:

english

File:

PDF, 2.72 MB

english, 2015

8

New Approaches in the Design and Development of Cannabinoid Receptor Ligands: Multifunctional and Bivalent Compounds

Nimczick, Martin, Decker, Michael

Journal:

Year:

2015

Language:

english

File:

PDF, 1.22 MB

english, 2015

9

Selective Inhibitors of the Protein Tyrosine Phosphatase SHP2 Block Cellular Motility and Growth of Cancer Cells in vitro and in vivo

Grosskopf, Stefanie, Eckert, Chris, Arkona, Christoph, Radetzki, Silke, Böhm, Kerstin, Heinemann, Udo, Wolber, Gerhard, von Kries, Jens-Peter, Birchmeier, Walter, Rademann, Jörg

Journal:

Year:

2015

Language:

english

File:

PDF, 3.87 MB

english, 2015

10

Can Silicon Make an Excellent Drug Even Better? An in vitro and in vivo Head-to-Head Comparison between Loperamide and Its Silicon Analogue Sila-Loperamide

Geyer, Marcel, Wellner, Eric, Jurva, Ulrik, Saloman, Sebastian, Armstrong, Duncan, Tacke, Reinhold

Journal:

Year:

2015

Language:

english

File:

PDF, 712 KB

english, 2015

11

Structure-Based Design of Drugs and Other Bioactive Molecules . Edited by Arun K. Ghosh and Sandra Gemma

Stocks, Michael

Journal:

Year:

2015

Language:

english

File:

PDF, 316 KB

english, 2015

12

Inside Cover: Novel 1,4-Substituted-1,2,3-Triazoles as Antitubercular Agents (ChemMedChem 5/2015)

Altimari, Jarrad M., Hockey, Samantha C., Boshoff, Helena I., Sajid, Andaleeb, Henderson, Luke C.

Journal:

Year:

2015

File:

PDF, 7.32 MB

2015

13

Back Cover: New Approaches in the Design and Development of Cannabinoid Receptor Ligands: Multifunctional and Bivalent Compounds (ChemMedChem 5/2015)

Nimczick, Martin, Decker, Michael

Journal:

Year:

2015

File:

PDF, 8.18 MB

2015

14

Antibiotics: Current Innovations and Future Trends . Edited by Sergio Sánchez and Arnold L. Demain

Schofield, Christopher

Journal:

Year:

2015

Language:

english

File:

PDF, 332 KB

english, 2015

15

Platinum(II) as Bifunctional Linker in Antibody-Drug Conjugate Formation: Coupling of a 4-Nitrobenzo-2-oxa-1,3-diazole Fluorophore to Trastuzumab as a Model

Waalboer, Dennis C. J., Muns, Joey A., Sijbrandi, Niels J., Schasfoort, Richard B. M., Haselberg, Rob, Somsen, Govert W., Houthoff, Hendrik-Jan, van Dongen, Guus A. M. S.

Journal:

Year:

2015

Language:

english

File:

PDF, 545 KB

english, 2015

16

Investigation of Structure-Activity Relationships of Synthetic Anti-Gonadotropin Releasing Hormone Vaccine Candidates

Chang, Chenghung, Varamini, Pegah, Giddam, Ashwini Kumar, Mansfeld, Friederike M., D'Occhio, Michael J., Toth, Istvan

Journal:

Year:

2015

Language:

english

File:

PDF, 2.73 MB

english, 2015

17

Controlling Toxicity of Peptide-Drug Conjugates by Different Chemical Linker Structures

Böhme, David, Beck-Sickinger, Annette G.

Journal:

Year:

2015

Language:

english

File:

PDF, 7.96 MB

english, 2015

18

Exploiting the Lactose-GM 3 Interaction for Drug Delivery

Murthy, Raghavendra Vasudeva, Bavireddi, Harikrishna, Gade, Madhuri, Kikkeri, Raghavendra

Journal:

Year:

2015

Language:

english

File:

PDF, 967 KB

english, 2015

19

Indanones As High-Potency Reversible Inhibitors of Monoamine Oxidase

Mostert, Samantha, Petzer, Anél, Petzer, Jacobus P.

Journal:

Year:

2015

Language:

english

File:

PDF, 1.21 MB

english, 2015

20

Ion Channel Drug Discovery . Edited by Brian Cox and Martin Gosling

Journal:

Year:

2015

Language:

english

File:

PDF, 453 KB

english, 2015

21

Spotlights on our sister journals: ChemMedChem 5/2015

Journal:

Year:

2015

Language:

english

File:

PDF, 7.07 MB

english, 2015

22

Cover Picture: Selective Inhibitors of the Protein Tyrosine Phosphatase SHP2 Block Cellular Motility and Growth of Cancer Cells in vitro and in vivo (ChemMedChem 5/2015)

Grosskopf, Stefanie, Eckert, Chris, Arkona, Christoph, Radetzki, Silke, Böhm, Kerstin, Heinemann, Udo, Wolber, Gerhard, von Kries, Jens-Peter, Birchmeier, Walter, Rademann, Jörg

Journal:

Year:

2015

File:

PDF, 725 KB

2015

23

Graphical Abstract: ChemMedChem 5/2015

Journal:

Year:

2015

Language:

english

File:

PDF, 6.31 MB

english, 2015

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