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Volume 3; Issue 10
Main
ChemMedChem
Volume 3; Issue 10
ChemMedChem
Volume 3; Issue 10
1
New DNA Polymerase IIIC Inhibitors: 3-Subtituted Anilinouracils with Potent Antibacterial Activity in vitro and in vivo
Niels Svenstrup
,
Kerstin Ehlert
,
Christoph Ladel
,
Alexander Kuhl
,
Dieter Häbich
Journal:
ChemMedChem
Year:
2008
Language:
english
File:
PDF, 308 KB
Your tags:
english, 2008
2
Biomedical Potentials of Crown Ethers: Prospective Antitumor Agents
Marijeta Kralj
,
Ljerka Tušek-Božić
,
Leo Frkanec
Journal:
ChemMedChem
Year:
2008
Language:
english
File:
PDF, 1.79 MB
Your tags:
english, 2008
3
Computational Studies to Discover a New NR2B/NMDA Receptor Antagonist and Evaluation of Pharmacological Profile
Rosaria Gitto
,
Laura De Luca
,
Stefania Ferro
,
Francesco Occhiuto
,
Stefania Samperi
,
Giovanbattista De Sarro
,
Emilio Russo
,
Lucia Ciranna
,
Lara Costa
,
Alba Chimirri
Journal:
ChemMedChem
Year:
2008
Language:
english
File:
PDF, 1.06 MB
Your tags:
english, 2008
4
Integrating Structure- and Ligand-Based Virtual Screening: Comparison of Individual, Parallel, and Fused Molecular Docking and Similarity Search Calculations on Multiple Targets
Lu Tan
,
Hanna Geppert
,
Mihiret T. Sisay
,
Michael Gütschow
,
Jürgen Bajorath
Journal:
ChemMedChem
Year:
2008
Language:
english
File:
PDF, 363 KB
Your tags:
english, 2008
5
A Potent Integrin Antagonist from a Small Library of Cyclic RGD Pentapeptide Mimics Including Benzyl-Substituted Azabicycloalkane Amino Acids
Daniela Arosio
,
Laura Belvisi
,
Lino Colombo
,
Matteo Colombo
,
Donatella Invernizzi
,
Leonardo Manzoni
,
Donatella Potenza
,
Massimo Serra
,
Massimo Castorina
,
Claudio Pisano
,
Carlo Scolastico
Journal:
ChemMedChem
Year:
2008
Language:
english
File:
PDF, 523 KB
Your tags:
english, 2008
6
Discovery of Novel Non-Cyclam Polynitrogenated CXCR4 Coreceptor Inhibitors
Sofia Pettersson
,
Violeta I. Pérez-Nueno
,
Laia Ros-Blanco
,
Raimon Puig de La Bellacasa
,
María Obdulia Rabal
,
Xavier Batllori
,
Bonaventura Clotet
,
Imma Clotet-Codina
,
Mercedes Armand-Ugón
,
José Esté
,
J
Journal:
ChemMedChem
Year:
2008
Language:
english
File:
PDF, 566 KB
Your tags:
english, 2008
7
Discovery of Water-Soluble Antioxidant Flavonols without Vasorelaxant Activity
Suwan Yap
,
Karen J. Loft
,
Owen L. Woodman
,
Spencer J. Williams
Journal:
ChemMedChem
Year:
2008
Language:
english
File:
PDF, 317 KB
Your tags:
english, 2008
8
Benzimidazolium Salts as Small, Nonpeptidic and BBB-Permeable Human Prolyl Oligopeptidase Inhibitors
Teresa Tarragó
,
Carme Masdeu
,
Elena Gómez
,
Nicolás Isambert
,
Rodolfo Lavilla
,
Ernest Giralt
Journal:
ChemMedChem
Year:
2008
Language:
english
File:
PDF, 562 KB
Your tags:
english, 2008
9
Scaffold-Hopping Cascade Yields Potent Inhibitors of 5-Lipoxygenase
Bettina Hofmann
,
Lutz Franke
,
Ewgenij Proschak
,
Yusuf Tanrikulu
,
Petra Schneider
,
Dieter Steinhilber
,
Gisbert Schneider
Journal:
ChemMedChem
Year:
2008
Language:
english
File:
PDF, 313 KB
Your tags:
english, 2008
10
Synthesis, Antiproliferative Evaluation, and Structure–Activity Relationships of 3-Arylquinolines
Zhu-Ping Xiao
,
Peng-cheng Lv
,
Suo-Ping Xu
,
Tao-Tao Zhu
,
Hai-Liang Zhu
Journal:
ChemMedChem
Year:
2008
Language:
english
File:
PDF, 204 KB
Your tags:
english, 2008
11
α-Naphthylaminopropan-2-ol Derivatives as BACE1 Inhibitors
Valentina Asso
,
Elisa Ghilardi
,
Simone Bertini
,
Maria Digiacomo
,
Carlotta Granchi
,
Filippo Minutolo
,
Simona Rapposelli
,
Andrea Bortolato
,
Stefano Moro
,
Marco Macchia
Journal:
ChemMedChem
Year:
2008
Language:
english
File:
PDF, 355 KB
Your tags:
english, 2008
12
The Discovery of Pyrano[3,4-b]indole-Based Allosteric Inhibitors of HCV NS5B Polymerase with In Vivo Activity
Matthew G. LaPorte
,
Randy W. Jackson
,
Tandy L. Draper
,
Janet A. Gaboury
,
Kristin Galie
,
Torsten Herbertz
,
Alison R. Hussey
,
Susan R. Rippin
,
Christopher A. Benetatos
,
Srinivas K. Chunduru
,
Joel S. Chr
Journal:
ChemMedChem
Year:
2008
Language:
english
File:
PDF, 354 KB
Your tags:
english, 2008
13
Inhibition of hERG Channel Trafficking: An Under-Explored Mechanism for Drug-Induced QT Prolongation
Kap-Sun Yeung
,
Nicholas A. Meanwell
Journal:
ChemMedChem
Year:
2008
Language:
english
File:
PDF, 144 KB
Your tags:
english, 2008
14
On the Art of Compiling and Using 'Drug-Like' Chemical Fragment Spaces
Jörg Degen
,
Christof Wegscheid-Gerlach
,
Andrea Zaliani
,
Matthias Rarey
Journal:
ChemMedChem
Year:
2008
Language:
english
File:
PDF, 334 KB
Your tags:
english, 2008
15
Structure-Based Optimization of Protein Tyrosine Phosphatase-1 B Inhibitors: Capturing Interactions with Arginine 24
Zhao-Kui Wan
,
Jinbo Lee
,
Rajeev Hotchandani
,
Alessandro Moretto
,
Eva Binnun
,
Douglas P. Wilson
,
Steve J. Kirincich
,
Bruce C. Follows
,
Manus Ipek
,
Weixin Xu
,
Diane Joseph-McCarthy
,
Yan-Ling Zhang
,
May
Journal:
ChemMedChem
Year:
2008
Language:
english
File:
PDF, 443 KB
Your tags:
english, 2008
16
Discovery of NMDA Glycine Site Inhibitors from the Chemical Universe Database GDB
Kong Thong Nguyen
,
Salahuddin Syed
,
Stephan Urwyler
,
Sonia Bertrand
,
Daniel Bertrand
,
Jean-Louis Reymond
Journal:
ChemMedChem
Year:
2008
Language:
english
File:
PDF, 274 KB
Your tags:
english, 2008
17
Anti-Inflammatory Activity of a New Class of Nitric Oxide Synthase Inhibitors That Release Nitric Oxide
Maurizio Botta
,
Eleonora Distrutti
,
Andrea Mencarelli
,
Maria Cristina Parlato
,
Francesco Raffi
,
Sabrina Cipriani
,
Stefano Fiorucci
Journal:
ChemMedChem
Year:
2008
Language:
english
File:
PDF, 425 KB
Your tags:
english, 2008
18
Apoptosis-Inducing High .NO Concentrations Are Not Sustained Either in Nascent or in Developed Cancers
Adam Heller
Journal:
ChemMedChem
Year:
2008
Language:
english
File:
PDF, 239 KB
Your tags:
english, 2008
19
Cover Picture: Computational Studies to Discover a New NR2B/NMDA Receptor Antagonist and Evaluation of Pharmacological Profile (ChemMedChem 10/2008)
Rosaria Gitto
,
Laura De Luca
,
Stefania Ferro
,
Francesco Occhiuto
,
Stefania Samperi
,
Giovanbattista De Sarro
,
Emilio Russo
,
Lucia Ciranna
,
Lara Costa
,
Alba Chimirri
Journal:
ChemMedChem
Year:
2008
File:
PDF, 828 KB
Your tags:
2008
20
Graphical Abstract: ChemMedChem 10/2008
Journal:
ChemMedChem
Year:
2008
Language:
english
File:
PDF, 737 KB
Your tags:
english, 2008
21
Spotlights on our sister journals: ChemMedChem 10/2008
Journal:
ChemMedChem
Year:
2008
Language:
english
File:
PDF, 385 KB
Your tags:
english, 2008
22
Preview: ChemMedChem 11/2008
Journal:
ChemMedChem
Year:
2008
Language:
english
File:
PDF, 94 KB
Your tags:
english, 2008
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