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Volume 3; Issue 2
Main
ChemMedChem
Volume 3; Issue 2
ChemMedChem
Volume 3; Issue 2
1
Cis-Configured Aziridines Are New Pseudo-Irreversible Dual-Mode Inhibitors of Candida albicans Secreted Aspartic Protease 2
Björn Degel
,
Peter Staib
,
Sebastian Rohrer
,
Josef Scheiber
,
Erika Martina
,
Christian Büchold
,
Knut Baumann
,
Joachim Morschhäuser
,
Tanja Schirmeister
Journal:
ChemMedChem
Year:
2008
Language:
english
File:
PDF, 960 KB
Your tags:
english, 2008
2
The Treatment of Dyslipidemia—What's Left in the Pipeline?
Oliver Rau
,
Heiko Zettl
,
Laura Popescu
,
Dieter Steinhilber
,
Manfred Schubert-Zsilavecz
Journal:
ChemMedChem
Year:
2008
Language:
english
File:
PDF, 647 KB
Your tags:
english, 2008
3
Virtual Screening and Experimental Verification to Identify Potential Inhibitors of the ErmC Methyltransferase Responsible for Bacterial Resistance against Macrolide Antibiotics
Marcin Feder
,
Elzbieta Purta
,
Lukasz Koscinski
,
Sonja Čubrilo
,
Gordana Maravic Vlahovicek
,
Janusz M. Bujnicki
Journal:
ChemMedChem
Year:
2008
Language:
english
File:
PDF, 361 KB
Your tags:
english, 2008
4
Generation of Carrier Peptides for the Delivery of Nucleic Acid Drugs in Primary Cells
Robert Rennert
,
Ines Neundorf
,
Heinz-Georg Jahnke
,
Philipp Suchowerskyj
,
Pascal Dournaud
,
Andrea Robitzki
,
Annette G. Beck-Sickinger
Journal:
ChemMedChem
Year:
2008
Language:
english
File:
PDF, 872 KB
Your tags:
english, 2008
5
Sensitive, Selective, and Irreversible Inhibition of Cyclooxygenase-2 Activity by Copper
Seiichi Nagano
,
Ashley I. Bush
Journal:
ChemMedChem
Year:
2008
Language:
english
File:
PDF, 197 KB
Your tags:
english, 2008
6
A Composite Model for hERG Blockade
Christian Kramer
,
Bernd Beck
,
Jan M. Kriegl
,
Timothy Clark
Journal:
ChemMedChem
Year:
2008
Language:
english
File:
PDF, 704 KB
Your tags:
english, 2008
7
Asymmetric Synthesis and Receptor Pharmacology of the Group II mGlu Receptor Ligand (1S,2R,3R,5R,6S)-2-Amino-3-hydroxy-bicyclo[3.1.0]hexane-2,6-dicarboxylic Acid—HYDIA
Thomas J. Woltering
,
Geo Adam
,
Philipp Huguenin
,
Jürgen Wichmann
,
Sabine Kolczewski
,
Silvia Gatti
,
Anne Bourson
,
James N. C. Kew
,
Grayson Richards
,
John A. Kemp
,
Vincent Mutel
,
Frédéric Knoflach
Journal:
ChemMedChem
Year:
2008
Language:
english
File:
PDF, 584 KB
Your tags:
english, 2008
8
Heteroaryl-Substituted 4-(1H-pyrazol-1-yl)-5,6-dihydro-1H-pyrrolo[2,3-d]pyrimidine Derivatives as Potent and Selective Corticotropin-Releasing Factor Receptor-1 Antagonists
Fabio Maria Sabbatini
,
Romano Di Fabio
,
Yves St-Denis
,
Anna-Maria Capelli
,
Emiliano Castiglioni
,
Stefania Contini
,
Daniele Donati
,
Elettra Fazzolari
,
Gabriella Gentile
,
Fabrizio Micheli
,
Francesca Pav
Journal:
ChemMedChem
Year:
2008
Language:
english
File:
PDF, 218 KB
Your tags:
english, 2008
9
Synthesis, Biological Evaluation, and Molecular Modeling Studies of Rebeccamycin Analogues Modified in the Carbohydrate Moiety
Fabio Animati
,
Marco Berettoni
,
Mario Bigioni
,
Monica Binaschi
,
Patrizia Felicetti
,
Lorenzo Gontrani
,
Ottaviano Incani
,
Andrea Madami
,
Edith Monteagudo
,
Lauso Olivieri
,
Stefano Resta
,
Cristina Rossi
,
Journal:
ChemMedChem
Year:
2008
Language:
english
File:
PDF, 657 KB
Your tags:
english, 2008
10
Exploring the Flap Pocket of the Antimalarial Target Plasmepsin II: The “55 % Rule” Applied to Enzymes
Martina Zürcher
,
Thomas Gottschalk
,
Solange Meyer
,
Daniel Bur
,
François Diederich
Journal:
ChemMedChem
Year:
2008
Language:
english
File:
PDF, 406 KB
Your tags:
english, 2008
11
Identification of Putative Binding Sites of P-glycoprotein Based on its Homology Model
Christoph Globisch
,
Ilza K. Pajeva
,
Michael Wiese
Journal:
ChemMedChem
Year:
2008
Language:
english
File:
PDF, 2.59 MB
Your tags:
english, 2008
12
Modeling and Selection of Flexible Proteins for Structure-Based Drug Design: Backbone and Side Chain Movements in p38 MAPK
Jyothi Subramanian
,
Somesh Sharma
,
Chandrika B-Rao
Journal:
ChemMedChem
Year:
2008
Language:
english
File:
PDF, 496 KB
Your tags:
english, 2008
13
Antiproliferative Agents That Interfere with the Cell Cycle at the G1→S Transition: Further Development and Characterization of a Small Library of Stilbene-Derived Compounds
Daniela Pizzirani
,
Marinella Roberti
,
Andrea Cavalli
,
Stefania Grimaudo
,
Antonietta Di Cristina
,
Rosaria Maria Pipitone
,
Nicola Gebbia
,
Manlio Tolomeo
,
Maurizio Recanatini
Journal:
ChemMedChem
Year:
2008
Language:
english
File:
PDF, 482 KB
Your tags:
english, 2008
14
D-SAP: A New, Noncytotoxic, and Fully Protease Resistant Cell-Penetrating Peptide
Sílvia Pujals
,
Jimena Fernández-Carneado
,
M. Dolors Ludevid
,
Ernest Giralt
Journal:
ChemMedChem
Year:
2008
Language:
english
File:
PDF, 929 KB
Your tags:
english, 2008
15
A Small Molecular Scaffold for Selective Inhibition of Wip1 Phosphatase
Jeong Bang
,
Hiroshi Yamaguchi
,
Stewart R. Durell
,
Ettore Appella
,
Daniel H. Appella
Journal:
ChemMedChem
Year:
2008
Language:
english
File:
PDF, 357 KB
Your tags:
english, 2008
16
Synthesis and Immobilization of erythro-C14-ω-Aminosphingosine-1-phosphate as a Potential Tool for Affinity Chromatography
Thomas Ullrich
,
Michael Ghobrial
,
Carsten Peters
,
Andreas Billich
,
Danilo Guerini
,
Peter Nussbaumer
Journal:
ChemMedChem
Year:
2008
Language:
english
File:
PDF, 210 KB
Your tags:
english, 2008
17
How Many Traditional Chinese Medicine Components Have Been Recognized by Modern Western Medicine? A Chemoinformatic Analysis and Implications for Finding Multicomponent Drugs
De-Xin Kong
,
Xue-Juan Li
,
Guang-Yan Tang
,
Hong-Yu Zhang
Journal:
ChemMedChem
Year:
2008
Language:
english
File:
PDF, 159 KB
Your tags:
english, 2008
18
Biochips as Pathways to Drug Discovery. Edited by Andrew Carmen and Gary Hardiman.
Matthew D. Disney
Journal:
ChemMedChem
Year:
2008
Language:
english
File:
PDF, 65 KB
Your tags:
english, 2008
19
Sport Doping—A Double Blind Proposal
Carl Djerassi
Journal:
ChemMedChem
Year:
2008
Language:
english
File:
PDF, 79 KB
Your tags:
english, 2008
20
Cover Picture: A Composite Model for hERG Blockade (ChemMedChem 2/2008)
Christian Kramer
,
Bernd Beck
,
Jan M. Kriegl
,
Timothy Clark
Journal:
ChemMedChem
Year:
2008
Language:
english
File:
PDF, 618 KB
Your tags:
english, 2008
21
Graphical Abstract: ChemMedChem 2/2008
Journal:
ChemMedChem
Year:
2008
Language:
english
File:
PDF, 730 KB
Your tags:
english, 2008
22
Alkoxymethylenephosphonate Analogues of (Lyso)phosphatidic Acid Stimulate Signaling Networks Coupled to the LPA2 Receptor
Joanna Gajewiak
,
Ryoko Tsukahara
,
Tamotsu Tsukahara
,
Yuko Fujiwara
,
Shuanxing Yu
,
Yiling Lu
,
Mandi Murph
,
Gordon B. Mills
,
Gabor Tigyi
,
Glenn D. Prestwich
Journal:
ChemMedChem
Year:
2008
File:
PDF, 58 KB
Your tags:
2008
23
Spotlights on our sister journals: ChemMedChem 2/2008
Journal:
ChemMedChem
Year:
2008
Language:
english
File:
PDF, 385 KB
Your tags:
english, 2008
24
Preview: ChemMedChem 3/2008
Journal:
ChemMedChem
Year:
2008
Language:
english
File:
PDF, 75 KB
Your tags:
english, 2008
25
Amphiphilic NO-Donor Antioxidants
Konstantin Chegaev
,
Loretta Lazzarato
,
Barbara Rolando
,
Elisabetta Marini
,
Gloria V. Lopez
,
Massimo Bertinaria
,
Antonella Di Stilo
,
Roberta Fruttero
,
Alberto Gasco
Journal:
ChemMedChem
Year:
2008
File:
PDF, 69 KB
Your tags:
2008
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