Volume 3; Issue 4

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ChemMedChem
Volume 3; Issue 4

ChemMedChem

Volume 3; Issue 4

1

Gastroesophageal Reflux Disease (GERD): Is There More to the Story?

Benjamin J. Vesper, Kenneth W. Altman, Kim M. Elseth, G. Kenneth Haines III, Sylvia I. Pavlova, Lin Tao, Gabor Tarjan, James A. Radosevich

Journal:

Year:

2008

Language:

english

File:

PDF, 405 KB

english, 2008

2

Molecular Models of the Interface between Anterior Pharynx-Defective Protein 1 (APH-1) and Presenilin Involving GxxxG Motifs

Krzysztof Jozwiak, Krystiana A. Krzysko, Lukasz Bojarski, Magdalena Gacia, Slawomir Filipek

Journal:

Year:

2008

Language:

english

File:

PDF, 650 KB

english, 2008

3

A Multidisciplinary Approach for the Identification of Novel HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors: S-DABOCs and DAVPs

Marco Radi, Chiara Falciani, Lorenzo Contemori, Elena Petricci, Giovanni Maga, Alberta Samuele, Samantha Zanoli, Montserrat Terrazas, Marinunzia Castria, Andrea Togninelli, José A. Esté, Imma Clotet-C

Journal:

Year:

2008

Language:

english

File:

PDF, 1.21 MB

english, 2008

4

Small-Molecule based Delivery Systems for Alkylating Antineoplastic Compounds

Krzysztof Bielawski, Anna Bielawska

Journal:

Year:

2008

Language:

english

File:

PDF, 247 KB

english, 2008

5

ESI-MS Studies on Prolyl Hydroxylase Domain 2 Reveal a New Metal Binding Site

Jasmin Mecinović, Rasheduzzaman Chowdhury, Benoît M. R. Liénard, Emily Flashman, Matthew R. G. Buck, Neil J. Oldham, Christopher J. Schofield

Journal:

Year:

2008

Language:

english

File:

PDF, 495 KB

english, 2008

6

Medicinal Chemistry Aspects of Drug Targets in Sphingolipid Metabolism

Peter Nussbaumer

Journal:

Year:

2008

Language:

english

File:

PDF, 261 KB

english, 2008

7

Modeling hERG and its Interactions with Drugs: Recent Advances in Light of Current Potassium Channel Simulations

Maurizio Recanatini, Andrea Cavalli, Matteo Masetti

Journal:

Year:

2008

Language:

english

File:

PDF, 778 KB

english, 2008

8

Non-Steroidal Aromatase Inhibitors Based on a Biphenyl Scaffold: Synthesis, in vitro SAR, and Molecular Modelling

Toby Jackson, L. W. Lawrence Woo, Melanie N. Trusselle, Atul Purohit, Michael J. Reed, Barry V. L. Potter

Journal:

Year:

2008

Language:

english

File:

PDF, 699 KB

english, 2008

9

Peptide-Containing Aggregates as Selective Nanocarriers for Therapeutics

Antonella Accardo, Diego Tesauro, Luigi Aloj, Laura Tarallo, Claudio Arra, Gaetano Mangiapia, Mauro Vaccaro, Carlo Pedone, Luigi Paduano, Giancarlo Morelli

Journal:

Year:

2008

Language:

english

File:

PDF, 561 KB

english, 2008

10

Small Interfering RNA-Mediated Silencing of Glutathione-S-Transferase A1 Sensitizes Hepatic Carcinoma Cells to Photodynamic Therapy with Pentaphyrins

Valentina Rapozzi, Cinzia Lombardo, Susanna Cogoi, Clara Comuzzi, Luigi Xodo

Journal:

Year:

2008

Language:

english

File:

PDF, 266 KB

english, 2008

11

Discovery of Potent, Orally Bioavailable Small-Molecule Inhibitors of the Human CCR2 Receptor

Julien Doyon, Erwin Coesemans, Staf Boeckx, Mieke Buntinx, Bart Hermans, Jean P. Van Wauwe, Ron A. H. J. Gilissen, Alex H. J. De Groot, David Corens, Guy Van Lommen

Journal:

Year:

2008

Language:

english

File:

PDF, 293 KB

english, 2008

12

Taxane Analogues against Breast Cancer: A Quantitative Structure–Activity Relationship Study

Rajeshwar P. Verma, Corwin Hansch

Journal:

Year:

2008

Language:

english

File:

PDF, 331 KB

english, 2008

13

Investigations on Surface Modified Dendrimers: Enzymatic Hydrolysis and Uptake into MCF-7 Breast Cancer Cells

Timo Kapp, Peter Francke, Ronald Gust

Journal:

Year:

2008

Language:

english

File:

PDF, 288 KB

english, 2008

14

Total Synthesis and Initial Structure–Activity Relationships of Longicatenamycin A

Franz von Nussbaum, Sonja Anlauf, Christoph Freiberg, Jordi Benet-Buchholz, Jens Schamberger, Thomas Henkel, Guido Schiffer, Dieter Häbich

Journal:

Year:

2008

Language:

english

File:

PDF, 413 KB

english, 2008

15

European Medicinal Chemistry Education: The Transformational Accomplishments and Challenges

Gloria Cristalli, Péter Mátyus, Peter Mohr, Giuseppe Ronsisvalle, Noel J. de Souza, Anna Tsantili-Kakoulidou

Journal:

Year:

2008

Language:

english

File:

PDF, 151 KB

english, 2008

16

A Successful Joint Effort

Journal:

Year:

2008

Language:

english

File:

PDF, 227 KB

english, 2008

17

Molecules that Changed the World. By K. C. Nicolaou and T. Montagnon.

Karl-Heinz Altmann

Journal:

Year:

2008

Language:

english

File:

PDF, 102 KB

english, 2008

18

Cover Picture: ESI-MS Studies on Prolyl Hydroxylase Domain 2 Reveal a New Metal Binding Site (ChemMedChem 4/2008)

Jasmin Mecinović, Rasheduzzaman Chowdhury, Benoît M. R. Liénard, Emily Flashman, Matthew R. G. Buck, Neil J. Oldham, Christopher J. Schofield

Journal:

Year:

2008

Language:

english

File:

PDF, 698 KB

english, 2008

19

Graphical Abstract: ChemMedChem 4/2008

Journal:

Year:

2008

Language:

english

File:

PDF, 424 KB

english, 2008

20

Spotlights on our sister journals: ChemMedChem 4/2008

Journal:

Year:

2008

Language:

english

File:

PDF, 269 KB

english, 2008

21

Preview: ChemMedChem 5/2008

Journal:

Year:

2008

Language:

english

File:

PDF, 94 KB

english, 2008

22

Changes of the Properties in the Upper Layers of Human Skin on Treatment with Models of Different Pharmaceutical Formulations—An Ex vivo ESR Imaging Study

Klaus-Peter Moll, Werner Herrmann, Reinhard Stößer, Hans-Hubert Borchert

Journal:

Year:

2008

Language:

english

File:

PDF, 258 KB

english, 2008