Volume 3; Issue 7

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ChemMedChem
Volume 3; Issue 7

ChemMedChem

Volume 3; Issue 7

1

Nitric Oxide Releasing Metal–Diazeniumdiolate Complexes Strongly Induce Vasorelaxation and Endothelial Cell Proliferation

Marina Ziche, Sandra Donnini, Lucia Morbidelli, Enrico Monzani, Raffaella Roncone, Roberta Gabbini, Luigi Casella

Journal:

Year:

2008

Language:

english

File:

PDF, 316 KB

english, 2008

2

α,α-Cyclopentaneglycine Dipeptides Capped with Biaryls as Tachykinin NK2 Receptor Antagonists

Marina Porcelloni, Piero D'Andrea, Cristina Rossi, Alessandro Sisto, Alessandro Ettorre, Andrea Madami, Maria Altamura, Sandro Giuliani, Stefania Meini, Daniela Fattori

Journal:

Year:

2008

Language:

english

File:

PDF, 371 KB

english, 2008

3

Synthesis and in vitro Evaluation of α-GalCer Epimers

Matthias Trappeniers, Stijn Goormans, Katrien Van Beneden, Tine Decruy, Bruno Linclau, Aymen Al-Shamkhani, Tim Elliott, Christian Ottensmeier, Joern M. Werner, Dirk Elewaut, Serge Van Calenbergh

Journal:

Year:

2008

Language:

english

File:

PDF, 388 KB

english, 2008

4

Isoquinolin-1-one Inhibitors of the MDM2–p53 Interaction

Ulli Rothweiler, Anna Czarna, Marcin Krajewski, Jolanta Ciombor, Cédric Kalinski, Vladimir Khazak, Günther Ross, Natalia Skobeleva, Lutz Weber, Tad A. Holak

Journal:

Year:

2008

Language:

english

File:

PDF, 827 KB

english, 2008

5

D-(+)-iso-Methanocarbathymidine: a High-Affinity Substrate for Herpes Simplex Virus 1 Thymidine Kinase

Maria J. Comin, B. Christie Vu, Paul L. Boyer, Chenzhong Liao, Stephen H. Hughes, Victor E. Marquez

Journal:

Year:

2008

Language:

english

File:

PDF, 417 KB

english, 2008

6

Phosphorylation by Sphingosine Kinase 2 is Essential for in vivo Potency of FTY720 Analogues

Klemens Högenauer, Andreas Billich, Charles Pally, Markus Streiff, Trixie Wagner, Karl Welzenbach, Peter Nussbaumer

Journal:

Year:

2008

Language:

english

File:

PDF, 234 KB

english, 2008

7

Synthesis of Somatostatin Mimetics Based on 1-Deoxynojirimycin

Vincent Chagnault, Jérôme Lalot, Paul V. Murphy

Journal:

Year:

2008

Language:

english

File:

PDF, 355 KB

english, 2008

8

Cellular Uptake, Cytotoxicity, and Metabolic Profiling of Human Cancer Cells Treated with Ruthenium(II) Polypyridyl Complexes [Ru(bpy)2(NN)]Cl2 with NN=bpy, phen, dpq, dppz, and dppn

Ulrich Schatzschneider, Johanna Niesel, Ingo Ott, Ronald Gust, Hamed Alborzinia, Stefan Wölfl

Journal:

Year:

2008

Language:

english

File:

PDF, 431 KB

english, 2008

9

Effects of Peripheral Chloro Substitution on the Photophysical Properties and in vitro Photodynamic Activities of Galactose-Conjugated Silicon(IV) Phthalocyanines

Pui-Chi Lo, Wing-Ping Fong, Dennis K. P. Ng

Journal:

Year:

2008

Language:

english

File:

PDF, 374 KB

english, 2008

10

Nonpeptidic Vinyl and Allyl Phosphonates as Falcipain-2 Inhibitors

Roberta Ettari, Emanuela Nizi, Maria Emilia Di Francesco, Nicola Micale, Silvana Grasso, Maria Zappalà, Radim Vičík, Tanja Schirmeister

Journal:

Year:

2008

Language:

english

File:

PDF, 208 KB

english, 2008

11

Synthesis, Antiproliferative Activity, and Structure–Activity Relationships of 3-Aryl-1H-quinolin-4-ones

Zhu-Ping Xiao, Huan-Qiu Li, Lei Shi, Peng-Cheng Lv, Zhong-Cheng Song, Hai-Liang Zhu

Journal:

Year:

2008

Language:

english

File:

PDF, 216 KB

english, 2008

12

Use of N-Methylpiperazine for the Preparation of Piperazine-Based Unsymmetrical Bis-Ureas as Anti-HIV Agents

Ayman El-Faham, Mercedes Armand-Ugón, Jose A. Esté, Fernando Albericio

Journal:

Year:

2008

Language:

english

File:

PDF, 225 KB

english, 2008

13

Exploring Acyclic Nucleoside Analogues as Inhibitors of Mycobacterium tuberculosis Thymidylate Kinase

Olga Familiar, Hélène Munier-Lehmann, Ana Negri, Federico Gago, Dominique Douguet, Leen Rigouts, Ana-Isabel Hernández, María-José Camarasa, María-Jesús Pérez-Pérez

Journal:

Year:

2008

Language:

english

File:

PDF, 341 KB

english, 2008

14

Crystal Structures of a Second G Protein-Coupled Receptor: Triumphs and Implications

Abby L. Parrill

Journal:

Year:

2008

Language:

english

File:

PDF, 235 KB

english, 2008

15

Allene as an Alternative Functional Group for Drug Design: Effect of CC Multiple Bonds Conjugated with Quinazolines on the Inhibition of EGFR Tyrosine Kinase

Hyun Seung Ban, Shinya Onagi, Masaharu Uno, Wataru Nabeyama, Hiroyuki Nakamura

Journal:

Year:

2008

Language:

english

File:

PDF, 609 KB

english, 2008

16

Necessity is the Mother of Invention: An Ingenious Method for Leukocyte-Targeted Delivery of siRNA in Stabilized Nanoparticles Demonstrates a Role of Cyclin D1 in Inflammation

Journal:

Year:

2008

Language:

english

File:

PDF, 152 KB

english, 2008

17

Telomerase Inhibition: Strategies and Protocols. Edited by Lucy G. Andrews and Trygve O. Tollefsbol.

Lionel Guittat, Jean-Louis Mergny

Journal:

Year:

2008

Language:

english

File:

PDF, 115 KB

english, 2008

18

Computational and Structural Approaches to Drug Discovery: Ligand–Protein Interactions. Edited by Robert M. Stroud and Janet Finer-Moore.

Journal:

Year:

2008

Language:

english

File:

PDF, 97 KB

english, 2008

19

Metallochemistry of Neurodegeneration: Biological, Chemical and Genetic Aspects. By Henryk Kozlowski, David R. Brown, and Gianni Valensin.

Shawn C. Burdette

Journal:

Year:

2008

Language:

english

File:

PDF, 76 KB

english, 2008

20

Thermal Analysis of Pharmaceuticals. Edited by Duncan Q. M. Craig and Mike Reading.

Journal:

Year:

2008

Language:

english

File:

PDF, 86 KB

english, 2008

21

Inhibitors of Cyclin-dependent Kinases as Antitumor Agents. Edited by Paul J. Smith and Eddy W. Yue.

Journal:

Year:

2008

Language:

english

File:

PDF, 75 KB

english, 2008

22

Cover Picture: Synthesis of Somatostatin Mimetics Based on 1-Deoxynojirimycin (ChemMedChem 7/2008)

Vincent Chagnault, Jérôme Lalot, Paul V. Murphy

Journal:

Year:

2008

File:

PDF, 657 KB

2008

23

Graphical Abstract: ChemMedChem 7/2008

Journal:

Year:

2008

Language:

english

File:

PDF, 641 KB

english, 2008

24

Spotlights on our sister journals: ChemMedChem 7/2008

Journal:

Year:

2008

Language:

english

File:

PDF, 357 KB

english, 2008

25

Preview: ChemMedChem 8/2008

Journal:

Year:

2008

Language:

english

File:

PDF, 75 KB

english, 2008