Volume 4; Issue 8

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ChemMedChem
Volume 4; Issue 8

ChemMedChem

Volume 4; Issue 8

1

Multimerization of Peptide Mimotopes for Blocking of Factor VIII Neutralizing Antibodies

Christoph Kessel, Wolfhart Kreuz, Katharina Klich, Karin Becker-Peters, Frank Vorpahl, Ursula Dietrich, Thomas Klingebiel, Christoph Königs

Journal:

Year:

2009

Language:

english

File:

PDF, 293 KB

english, 2009

2

Synthesis and Antimalarial Properties of Streptocyanine Dyes

Marie-Pierre Maether, Denis Desoubzdanne, Albert Izquierdo, Valérie Guieu, Marie Maturano, Christiane André-Barrès, Alexis Valentin, Valérie Jullian, Séverine Chevalley, Marjorie Maynadier, Henri Vial

Journal:

Year:

2009

Language:

english

File:

PDF, 239 KB

english, 2009

3

Screening for the Drug–Phospholipid Interaction: Correlation to Phospholipidosis

Juha-Matti Alakoskela, Pavol Vitovič, Paavo K. J. Kinnunen

Journal:

Year:

2009

Language:

english

File:

PDF, 1.55 MB

english, 2009

4

Pharmacophore-Based Discovery of Small-Molecule Inhibitors of Protein–Protein Interactions between HIV-1 Integrase and Cellular Cofactor LEDGF/p75

Laura De Luca, Maria Letizia Barreca, Stefania Ferro, Frauke Christ, Nunzio Iraci, Rosaria Gitto, Anna Maria Monforte, Zeger Debyser, Alba Chimirri

Journal:

Year:

2009

Language:

english

File:

PDF, 688 KB

english, 2009

5

PAMAM Dendrimers Mediate siRNA Delivery to Target Hsp27 and Produce Potent Antiproliferative Effects on Prostate Cancer Cells

Xiao-xuan Liu, Palma Rocchi, Fan-qi Qu, Shu-quan Zheng, Zi-cai Liang, Martin Gleave, Juan Iovanna, Ling Peng

Journal:

Year:

2009

Language:

english

File:

PDF, 559 KB

english, 2009

6

Discovery of Plasmepsin Inhibitors by Fragment-Based Docking and Consensus Scoring

Ran Friedman, Amedeo Caflisch

Journal:

Year:

2009

Language:

english

File:

PDF, 657 KB

english, 2009

7

Chemistry and Pharmacology of Nicotinic Ligands Based on 6-[5-(Azetidin-2-ylmethoxy)pyridin-3-yl]hex-5-yn-1-ol (AMOP-H-OH) for Possible Use in Depression

Alan P. Kozikowski, J. Brek Eaton, Krishna Mohan Bajjuri, Sheela K. Chellappan, Yihua Chen, Sudhakar Karadi, Rong He, Barbara Caldarone, Michael Manzano, Po-Wai Yuen, Ronald J. Lukas

Journal:

Year:

2009

Language:

english

File:

PDF, 448 KB

english, 2009

8

Stereoselective HDAC Inhibition from Cysteine-Derived Zinc-Binding Groups

Kyle V. Butler, Rong He, Kathryn McLaughlin, Giulio Vistoli, Brett Langley, Alan P. Kozikowski

Journal:

Year:

2009

Language:

english

File:

PDF, 603 KB

english, 2009

9

Improved Tricyclic Inhibitors of Trypanothione Reductase by Screening and Chemical Synthesis

John L. Richardson, Isabelle R. E. Nett, Deuan C. Jones, Mohamed H. Abdille, Ian H. Gilbert, Alan H. Fairlamb

Journal:

Year:

2009

Language:

english

File:

PDF, 387 KB

english, 2009

10

Synthesis and Evaluation of 1-(1-(Benzo[b]thiophen-2-yl)cyclohexyl)piperidine (BTCP) Analogues as Inhibitors of Trypanothione Reductase

Stephen Patterson, Deuan C. Jones, Emma J. Shanks, Julie A. Frearson, Ian H. Gilbert, Paul G. Wyatt, Alan H. Fairlamb

Journal:

Year:

2009

Language:

english

File:

PDF, 403 KB

english, 2009

11

Macromolecular Drug Delivery. Edited by Mattias Belting.

Journal:

Year:

2009

Language:

english

File:

PDF, 108 KB

english, 2009

12

Synthesis and Biological Evaluation of C7-Demethyl Largazole Analogues

Fei Chen, An-Hui Gao, Jia Li, Fa-Jun Nan

Journal:

Year:

2009

Language:

english

File:

PDF, 436 KB

english, 2009

13

Screening of Various Hormone-Sensitive Lipase Inhibitors as Endocannabinoid-Hydrolyzing Enzyme Inhibitors

Anna Minkkilä, Juha R. Savinainen, Heikki Käsnänen, Henri Xhaard, Tapio Nevalainen, Jarmo T. Laitinen, Antti Poso, Jukka Leppänen, Susanna M. Saario

Journal:

Year:

2009

Language:

english

File:

PDF, 700 KB

english, 2009

14

Molecular Targeting in Oncology. Edited by H. L. Kaufman, S. Wadler and K. Antman.

Journal:

Year:

2009

Language:

english

File:

PDF, 128 KB

english, 2009

15

Elastic Potential Grids: Accurate and Efficient Representation of Intermolecular Interactions for Fully Flexible Docking

Sina Kazemi, Dennis M. Krüger, Finton Sirockin, Holger Gohlke

Journal:

Year:

2009

Language:

english

File:

PDF, 779 KB

english, 2009

16

Frontiers in Medicinal Chemistry 2009—a Summary of the Meeting at Heidelberg University

Christian Gege, Christian D. Klein

Journal:

Year:

2009

Language:

english

File:

PDF, 194 KB

english, 2009

17

North- and South-Bicyclo[3.1.0]Hexene Nucleosides: The Effect of Ring Planarity on Anti-HIV Activity

Pamela L. Russ, Maria J. Gonzalez-Moa, B. Christie Vu, Dina M. Sigano, James A. Kelley, Christopher C. Lai, Jeffrey R. Deschamps, Stephen H. Hughes, Victor E. Marquez

Journal:

Year:

2009

Language:

english

File:

PDF, 363 KB

english, 2009

18

Strategies for Organic Drug Synthesis and Design. By Daniel Lednicer.

Thorleif Anthonsen

Journal:

Year:

2009

Language:

english

File:

PDF, 97 KB

english, 2009

19

β-Lactones Decrease the Intracellular Virulence of Listeria monocytogenes in Macrophages

Thomas Böttcher, Stephan A. Sieber

Journal:

Year:

2009

Language:

english

File:

PDF, 431 KB

english, 2009

20

Design, Selection, and Evaluation of a General Kinase-Focused Library

Hélène Decornez, Anna Gulyás-Forró, Ákos Papp, Miklós Szabó, Gabriella Sármay, István Hajdú, Sándor Cseh, György Dormán, Douglas B. Kitchen

Journal:

Year:

2009

Language:

english

File:

PDF, 330 KB

english, 2009

21

Bioorganic and Medicinal Chemistry of Fluorine. By Jean-Pierre Bégué and Danièle Bonnet-Delpon.

Thierry Billard

Journal:

Year:

2009

Language:

english

File:

PDF, 139 KB

english, 2009

22

Cover Picture: Improved Tricyclic Inhibitors of Trypanothione Reductase by Screening and Chemical Synthesis / Synthesis and Evaluation of 1-(1-(Benzo[b]thiophen-2-yl)cyclohexyl)piperidine (BTCP) Analogues as Inhibitors of Trypanothione Reductase (ChemMedChem 8/2009)

John L. Richardson, Isabelle R. E. Nett, Deuan C. Jones, Mohamed H. Abdille, Ian H. Gilbert, Alan H. Fairlamb, Stephen Patterson, Deuan C. Jones, Emma J. Shanks, Julie A. Frearson, Paul G. Wyatt

Journal:

Year:

2009

Language:

english

File:

PDF, 1.00 MB

english, 2009

23

Inside Cover: North- and South-Bicyclo[3.1.0]Hexene Nucleosides: The Effect of Ring Planarity on Anti-HIV Activity (ChemMedChem 8/2009)

Pamela L. Russ, Maria J. Gonzalez-Moa, B. Christie Vu, Dina M. Sigano, James A. Kelley, Christopher C. Lai, Jeffrey R. Deschamps, Stephen H. Hughes, Victor E. Marquez

Journal:

Year:

2009

Language:

english

File:

PDF, 471 KB

english, 2009

24

Graphical Abstract: ChemMedChem 8/2009

Journal:

Year:

2009

Language:

english

File:

PDF, 1.01 MB

english, 2009

25

Synthesis and Biological Evaluation of C7-Demethyl Largazole Analogues

Fei Chen, An-Hui Gao, Jia Li, Fa-Jun Nan

Journal:

Year:

2009

Language:

english

File:

PDF, 57 KB

english, 2009

26

Spotlights on our sister journals: ChemMedChem 8/2009

Journal:

Year:

2009

Language:

english

File:

PDF, 557 KB

english, 2009

27

Preview: ChemMedChem 9/2009

Journal:

Year:

2009

Language:

english

File:

PDF, 80 KB

english, 2009

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