Volume 5; Issue 1

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ChemMedChem
Volume 5; Issue 1

ChemMedChem

Volume 5; Issue 1

1

Bisubstrate Inhibitors of Protein Kinases: from Principle to Practical Applications

Darja Lavogina, Erki Enkvist, Asko Uri

Journal:

Year:

2010

Language:

english

File:

PDF, 888 KB

english, 2010

2

Evaluation of Novel Epothilone Analogues by means of a Common Pharmacophore and a QSAR Pseudoreceptor Model for Taxanes and Epothilones

Stefano Forli, Fabrizio Manetti, Karl-Heinz Altmann, Maurizio Botta

Journal:

Year:

2010

Language:

english

File:

PDF, 553 KB

english, 2010

3

Comparison of Structure- and Ligand-Based Virtual Screening Protocols Considering Hit List Complementarity and Enrichment Factors

Dennis M. Krüger, Andreas Evers

Journal:

Year:

2010

Language:

english

File:

PDF, 1.41 MB

english, 2010

4

New Antimicrobial Hexapeptides: Synthesis, Antimicrobial Activities, Cytotoxicity, and Mechanistic Studies

Rohit K. Sharma, Sandeep Sundriyal, Nishima Wangoo, Werner Tegge, Rahul Jain

Journal:

Year:

2010

Language:

english

File:

PDF, 372 KB

english, 2010

5

Hyaluronan in Cancer Biology. Edited by Robert Stern.

Journal:

Year:

2010

Language:

english

File:

PDF, 72 KB

english, 2010

6

Synthesis, Enzymatic Evaluation, and Docking Studies of Fluorogenic Caspase 8 Tetrapeptide Substrates

Przemysław Reszka, Riad Schulz, Karen Methling, Michael Lalk, Patrick J. Bednarski

Journal:

Year:

2010

Language:

english

File:

PDF, 910 KB

english, 2010

7

Bisnaphthalimidopropyl Derivatives as Inhibitors of Leishmania SIR2 Related Protein 1

Joana Tavares, Ali Ouaissi, Paul Kong Thoo Lin, Inês Loureiro, Simranjeet Kaur, Nilanjan Roy, Anabela Cordeiro-da-Silva

Journal:

Year:

2010

Language:

english

File:

PDF, 708 KB

english, 2010

8

Anticancer Therapeutics That Target Selenoenzymes: Synthesis, Characterization, in vitro Cytotoxicity, and Thioredoxin Reductase Inhibition of a Series of Gold(I) Complexes Containing Hydrophilic Phosphine Ligands

Elena Vergara, Angela Casini, Francesca Sorrentino, Olivier Zava, Elena Cerrada, Maria Pia Rigobello, Alberto Bindoli, Mariano Laguna, Paul J. Dyson

Journal:

Year:

2010

Language:

english

File:

PDF, 500 KB

english, 2010

9

Discovery of Potent Vascular Endothelial Growth Factor Receptor-2 Inhibitors

Athanasios Papakyriakou, Maria E. Katsarou, Maria Belimezi, Michael Karpusas, Dionisios Vourloumis

Journal:

Year:

2010

Language:

english

File:

PDF, 802 KB

english, 2010

10

Post-translational Modification of Protein Biopharmaceuticals. Edited by Gary Walsh.

Benjamin G. Davis

Journal:

Year:

2010

Language:

english

File:

PDF, 85 KB

english, 2010

11

Modulation on C- and N-Terminal Moieties of a Series of Potent and Selective Linear Tachykinin NK2 Receptor Antagonists

Martina Gensini, Maria Altamura, Tula Dimoulas, Valentina Fedi, Danilo Giannotti, Sandro Giuliani, Antonio Guidi, Nicholas J. S. Harmat, Stefania Meini, Rossano Nannicini, Franco Pasqui, Manuela Tramo

Journal:

Year:

2010

Language:

english

File:

PDF, 402 KB

english, 2010

12

Optimisation of Conoidin A, a Peroxiredoxin Inhibitor

Gu Liu, Catherine H. Botting, Kathryn M. Evans, Jeffrey A. G. Walton, Guogang Xu, Alexandra M. Z. Slawin, Nicholas J. Westwood

Journal:

Year:

2010

Language:

english

File:

PDF, 440 KB

english, 2010

13

Novel Imatinib Derivatives with Altered Specificity between Bcr–Abl and FMS, KIT, and PDGF Receptors

Konstantinos Skobridis, Maria Kinigopoulou, Vassiliki Theodorou, Emilia Giannousi, Alison Russell, Rakhee Chauhan, Roberta Sala, Nicola Brownlow, Serafim Kiriakidis, Jan Domin, Andreas G. Tzakos, Nick

Journal:

Year:

2010

Language:

english

File:

PDF, 650 KB

english, 2010

14

Water-soluble Organometallic Analogues of Oxaliplatin with Cytotoxic and Anticlonogenic Activity

Michele Benedetti, Daniela Antonucci, Danilo Migoni, Vita M. Vecchio, Cosimo Ducani, Francesco P. Fanizzi

Journal:

Year:

2010

Language:

english

File:

PDF, 319 KB

english, 2010

15

Neuroprotective Effects of N-Alkyl-1,2,4-oxadiazolidine-3,5-diones and Their Corresponding Synthetic Intermediates N-Alkylhydroxylamines and N-1-Alkyl-3-carbonyl-1-hydroxyureas against in vitro Cerebral Ischemia

Alain Cesar Biraboneye, Sebastien Madonna, Pamela Maher, Jean-Louis Kraus

Journal:

Year:

2010

Language:

english

File:

PDF, 261 KB

english, 2010

16

Synthesis and Evaluation of Hybrid Bis-cationic Salts as Antimalarial Drugs

Stéphanie Ortial, Séverine Denoyelle, Sharon Wein, Olivier Berger, Thierry Durand, Roger Escale, Alain Pellet, Henri Vial, Yen Vo-Hoang

Journal:

Year:

2010

Language:

english

File:

PDF, 216 KB

english, 2010

17

Editorial: High Five!

Peter Gölitz, Natalia Ortúzar, Scott D. Williams

Journal:

Year:

2010

Language:

english

File:

PDF, 482 KB

english, 2010

18

Rational Design of Amyloid Binding Agents Based on the Molecular Rotor Motif

Jeyanthy Sutharsan, Marianna Dakanali, Christina C. Capule, Mark A. Haidekker, Jerry Yang, Emmanuel A. Theodorakis

Journal:

Year:

2010

Language:

english

File:

PDF, 284 KB

english, 2010

19

Inhibitors of Cathepsins K and S Identified Using the DynaMAD Virtual Screening Algorithm

Dagmar Stumpfe, Mihiret T. Sisay, Maxim Frizler, Ingo Vogt, Michael Gütschow, Jürgen Bajorath

Journal:

Year:

2010

Language:

english

File:

PDF, 329 KB

english, 2010

20

Cover Picture: Evaluation of Novel Epothilone Analogues by means of a Common Pharmacophore and a QSAR Pseudoreceptor Model for Taxanes and Epothilones (ChemMedChem 1/2010)

Stefano Forli, Fabrizio Manetti, Karl-Heinz Altmann, Maurizio Botta

Journal:

Year:

2010

File:

PDF, 922 KB

2010

21

Spotlights on our sister journals: ChemMedChem 1/2010

Journal:

Year:

2010

Language:

english

File:

PDF, 750 KB

english, 2010

22

Preview: ChemMedChem 2/2010

Journal:

Year:

2010

Language:

english

File:

PDF, 73 KB

english, 2010

23

Inside Cover: Anticancer Therapeutics That Target Selenoenzymes: Synthesis, Characterization, in vitro Cytotoxicity, and Thioredoxin Reductase Inhibition of a Series of Gold(I) Complexes Containing Hydrophilic Phosphine Ligands (ChemMedChem 1/2010)

Elena Vergara, Angela Casini, Francesca Sorrentino, Olivier Zava, Elena Cerrada, Maria Pia Rigobello, Alberto Bindoli, Mariano Laguna, Paul J. Dyson

Journal:

Year:

2010

Language:

english

File:

PDF, 513 KB

english, 2010

24

Graphical Abstract: ChemMedChem 1/2010

Journal:

Year:

2010

Language:

english

File:

PDF, 1.58 MB

english, 2010