Volume 5; Issue 11

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ChemMedChem
Volume 5; Issue 11

ChemMedChem

Volume 5; Issue 11

1

The Active Core in a Triazole Peptide Dual-Site Antagonist of HIV-1 gp120

Dr. Muddegowda Umashankara, Karyn McFadden, Isaac Zentner, Dr. Arne Schön, Dr. Srivats Rajagopal, Ferit Tuzer, Syna A. Kuriakose, Dr. Mark Contarino, Dr. Judith LaLonde, Prof. Ernesto Freire, Prof. Ir

Journal:

Year:

2010

Language:

english

File:

PDF, 835 KB

english, 2010

2

A Novel Synthetic Route for the Anti-HIV Drug MC-1220 and its Analogues

Dr. Yasser M. Loksha, Daniel Globisch, Dr. Roberta Loddo, Dr. Gabriella Collu, Prof. Paolo La Colla, Prof. Erik B. Pedersen

Journal:

Year:

2010

Language:

english

File:

PDF, 181 KB

english, 2010

3

Studies of Anti-HIV Transcription Inhibitor Quinolones: Identification of Potent N1-Vinyl Derivatives

Prof. Oriana Tabarrini, Dr. Serena Massari, Dr. Dirk Daelemans, Dr. Francesco Meschini, Dr. Giuseppe Manfroni, Dr. Laura Bottega, Prof. Barbara Gatto, Prof. Manlio Palumbo, Prof. Christophe Pannecouqu

Journal:

Year:

2010

Language:

english

File:

PDF, 416 KB

english, 2010

4

Towards the Discovery of New Hypnotic Agents: Synthesis and Preliminary Pharmacological Evaluation of a Novel Class of Dibenzo[a,d]cycloheptene Derivatives

Dr. Emiliano Castiglioni, Dr. Romano Di Fabio, Dr. Andrea Togninelli, Dr. Stephen Brough, Dr. Fiona Brown, Dr. Michele Dal Cin, Dr. Massimo Gianotti, Dr. Carla Marchioro, Dr. Giancarlo Merlo, Dr. Raff

Journal:

Year:

2010

Language:

english

File:

PDF, 200 KB

english, 2010

5

Development of Peptide and Small-Molecule HIV-1 Fusion Inhibitors that Target gp41

Dr. Lifeng Cai, Prof. Shibo Jiang

Journal:

Year:

2010

Language:

english

File:

PDF, 674 KB

english, 2010

6

Inhibition of HIV-1 Entry: Multiple Keys to Close the Door

Maria Hertje, Mingkui Zhou, Dr. Ursula Dietrich

Journal:

Year:

2010

Language:

english

File:

PDF, 426 KB

english, 2010

7

Hypoxia-Selective Growth Inhibition of Cancer Cells by Furospinosulin-1, a Furanosesterterpene Isolated from an Indonesian Marine Sponge

Dr. Masayoshi Arai, Takashi Kawachi, Dr. Andi Setiawan, Dr. Motomasa Kobayashi

Journal:

Year:

2010

Language:

english

File:

PDF, 405 KB

english, 2010

8

Target Profiling of a Small Library of Phosphodiesterase 5 (PDE5) Inhibitors using Chemical Proteomics

Dr. Reinout Raijmakers, Dr. Poupak Dadvar, Dr. Sarah Pelletier, Dr. Joost Gouw, Dr. Klaus Rumpel, Prof. Dr. Albert J. R. Heck

Journal:

Year:

2010

Language:

english

File:

PDF, 588 KB

english, 2010

9

Toward the First Nonpeptidic Molecular Tong Inhibitor of Wild-Type and Mutated HIV-1 Protease Dimerization

Dr. Anamaria Vidu, Laure Dufau, Dr. Ludovic Bannwarth, Dr. Jean-Louis Soulier, Prof. Sames Sicsic, Prof. Umberto Piarulli, Prof. Michèle Reboud-Ravaux, Dr. Sandrine Ongeri

Journal:

Year:

2010

Language:

english

File:

PDF, 326 KB

english, 2010

10

Phosphoramidate Prodrugs Deliver with Potency Against Hepatitis C Virus

Dr. Youcef Mehellou

Journal:

Year:

2010

Language:

english

File:

PDF, 149 KB

english, 2010

11

Fusion Intermediates of HIV-1 gp41 as Targets for Antibody Production: Design, Synthesis, and HR1–HR2 Complex Purification and Characterization of Generated Antibodies

Olfa Mzoughi, Dr. Fabrice Gaston, Dr. Giovana C. Granados, Dr. Faouzi Lakhdar-Ghazal, Prof. Ernest Giralt, Prof. Elmostafa Bahraoui

Journal:

Year:

2010

Language:

english

File:

PDF, 1.01 MB

english, 2010

12

Enzyme Inhibition in Drug Discovery and Development: The Good and the Bad. Edited by Chuang Lu and Albert P. Li.

Dr. Maria Paola Costi

Journal:

Year:

2010

Language:

english

File:

PDF, 82 KB

english, 2010

13

Probing Multidrug-Resistance and Protein–Ligand Interactions with Oxatricyclic Designed Ligands in HIV-1 Protease Inhibitors

Prof. Dr. Arun K. Ghosh, Dr. Chun-Xiao Xu, Dr. Kalapala Venkateswara Rao, Abigail Baldridge, Johnson Agniswamy, Yuan-Fang Wang, Prof. Dr. Irene T. Weber, Manabu Aoki, Salcedo Gomez Pedro Miguel, Masay

Journal:

Year:

2010

Language:

english

File:

PDF, 342 KB

english, 2010

14

Novel Huprine Derivatives with Inhibitory Activity toward β-Amyloid Aggregation and Formation as Disease-Modifying Anti-Alzheimer Drug Candidates

Elisabet Viayna, Tània Gómez, Carles Galdeano, Lorena Ramírez, Dr. Míriam Ratia, Prof. Albert Badia, Prof. M. Victòria Clos, Dr. Ester Verdaguer, Dr. Félix Junyent, Prof. Antoni Camins, Prof. Mercè Pa

Journal:

Year:

2010

Language:

english

File:

PDF, 753 KB

english, 2010

15

A Turning Point in The Fight against HIV

Scott D. Williams

Journal:

Year:

2010

Language:

english

File:

PDF, 189 KB

english, 2010

16

Feeding the Antimalarial Pipeline

Prof. Dr. Martin Schlitzer, Dr. Regina Ortmann

Journal:

Year:

2010

Language:

english

File:

PDF, 160 KB

english, 2010

17

Synthesis of Imidazothiazole–Chalcone Derivatives as Anticancer and Apoptosis Inducing Agents

Dr. Ahmed Kamal, D. Dastagiri, Dr. M. Janaki Ramaiah, J. Surendranadha Reddy, E. Vijaya Bharathi, Chatla Srinivas, S. N. C. V. L. Pushpavalli, Dhananjaya Pal, Dr. Manika Pal-Bhadra

Journal:

Year:

2010

Language:

english

File:

PDF, 410 KB

english, 2010

18

Synthesis, In Vitro and In Vivo Release Kinetics, and Anti-HIV Activity of A Sustained-Release Prodrug (mPEG-AZT) of 3′-Azido-3′-deoxythymidine (AZT, Zidovudine)

Dr. Wenjun Li, Yu Chang, Peng Zhan, Prof. Dr. Na Zhang, Prof. Dr. Xinyong Liu, Prof. Dr. Christophe Pannecouque, Prof. Dr. Erik De Clercq

Journal:

Year:

2010

Language:

english

File:

PDF, 337 KB

english, 2010

19

Targeting Protein Kinases for Cancer Therapy. By David J. Matthews and Mary E. Gerritsen.

Dr. Daniel Kuhn

Journal:

Year:

2010

Language:

english

File:

PDF, 113 KB

english, 2010

20

Cover Picture: Probing Multidrug-Resistance and Protein–Ligand Interactions with Oxatricyclic Designed Ligands in HIV-1 Protease Inhibitors (ChemMedChem 11/2010)

Prof. Dr. Arun K. Ghosh, Dr. Chun-Xiao Xu, Dr. Kalapala Venkateswara Rao, Abigail Baldridge, Johnson Agniswamy, Yuan-Fang Wang, Prof. Dr. Irene T. Weber, Manabu Aoki, Salcedo Gomez Pedro Miguel, Masay

Journal:

Year:

2010

Language:

english

File:

PDF, 929 KB

english, 2010

21

Inside Cover: Studies of Anti-HIV Transcription Inhibitor Quinolones: Identification of Potent N1-Vinyl Derivatives (ChemMedChem 11/2010)

Prof. Oriana Tabarrini, Dr. Serena Massari, Dr. Dirk Daelemans, Dr. Francesco Meschini, Dr. Giuseppe Manfroni, Dr. Laura Bottega, Prof. Barbara Gatto, Prof. Manlio Palumbo, Prof. Christophe Pannecouqu

Journal:

Year:

2010

Language:

english

File:

PDF, 529 KB

english, 2010

22

Graphical Abstract: ChemMedChem 11/2010

Journal:

Year:

2010

Language:

english

File:

PDF, 481 KB

english, 2010

23

Spotlights on our sister journals: ChemMedChem 11/2010

Journal:

Year:

2010

Language:

english

File:

PDF, 828 KB

english, 2010

24

Preview: ChemMedChem 12/2010

Journal:

Year:

2010

Language:

english

File:

PDF, 85 KB

english, 2010