Volume 5; Issue 7

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ChemMedChem
Volume 5; Issue 7

ChemMedChem

Volume 5; Issue 7

1

Dual-Acting Drugs: an in vitro Study of Nonimidazole Histamine H3 Receptor Antagonists Combining Anticholinesterase Activity

Matteo Incerti, Lisa Flammini, Francesca Saccani, Giovanni Morini, Mara Comini, Massimo Coruzzi, Elisabetta Barocelli, Vigilio Ballabeni, Simona Bertoni

Journal:

Year:

2010

Language:

english

File:

PDF, 245 KB

english, 2010

2

Tautomerism and Magnesium Chelation of HIV-1 Integrase Inhibitors: A Theoretical Study

Chenzhong Liao, Marc C. Nicklaus

Journal:

Year:

2010

Language:

english

File:

PDF, 1.90 MB

english, 2010

3

Synthesis and Antitumor Activity of Ether Glycerophospholipids Bearing a Carbamate Moiety at the sn-2 Position: Selective Sensitivity Against Prostate Cancer Cell Lines

Hoe-Sup Byun, Robert Bittman, Pranati Samadder, Gilbert Arthur

Journal:

Year:

2010

Language:

english

File:

PDF, 438 KB

english, 2010

4

Cancer Drug Discovery and Development–Hormone Therapy in Breast and Prostate Cancer. Edited by V. Craig Jordan and Barrington J. A. Furr.

Ross V. Weatherman

Journal:

Year:

2010

Language:

english

File:

PDF, 109 KB

english, 2010

5

Discovery of Adamantyl Ethanone Derivatives as Potent 11β-Hydroxysteroid Dehydrogenase Type 1 (11β-HSD1) Inhibitors

Xiangdong Su, Fabienne Pradaux-Caggiano, Mark P. Thomas, Michelle W. Y. Szeto, Heather A. Halem, Michael D. Culler, Nigel Vicker, Barry V. L. Potter

Journal:

Year:

2010

Language:

english

File:

PDF, 858 KB

english, 2010

6

A Combined High-Resolution Mass Spectrometric and in silico Approach for the Characterisation of Small Ligands of β2-Microglobulin

Luca Regazzoni, Laura Bertoletti, Giulio Vistoli, Raffaella Colombo, Giancarlo Aldini, Massimo Serra, Marina Carini, Gabriele Caccialanza, Ersilia De Lorenzi

Journal:

Year:

2010

Language:

english

File:

PDF, 720 KB

english, 2010

7

Thiazolopyrimidine Inhibitors of 2-Methylerythritol 2,4-Cyclodiphosphate Synthase (IspF) from Mycobacterium tuberculosis and Plasmodium falciparum

Julie G. Geist, Susan Lauw, Victoria Illarionova, Boris Illarionov, Markus Fischer, Tobias Gräwert, Felix Rohdich, Wolfgang Eisenreich, Johannes Kaiser, Michael Groll, Christian Scheurer, Sergio Wittl

Journal:

Year:

2010

Language:

english

File:

PDF, 515 KB

english, 2010

8

High-Throughput Virtual Screening Using Quantum Mechanical Probes: Discovery of Selective Kinase Inhibitors

Ting Zhou, Amedeo Caflisch

Journal:

Year:

2010

Language:

english

File:

PDF, 428 KB

english, 2010

9

NMR-Guided Molecular Docking of a Protein–Peptide Complex Based on Ant Colony Optimization

Oliver Korb, Heiko M. Möller, Thomas E. Exner

Journal:

Year:

2010

Language:

english

File:

PDF, 624 KB

english, 2010

10

Synthesis and Evaluation of Bis-Thiazolium Salts as Potential Antimalarial Drugs

Sergio A. Caldarelli, Jean-Frédéric Duckert, Sharon Wein, Michèle Calas, Christian Périgaud, Henri Vial, Suzanne Peyrottes

Journal:

Year:

2010

Language:

english

File:

PDF, 271 KB

english, 2010

11

Homology Modelling of the GABA Transporter and Analysis of Tiagabine Binding

Søren Skovstrup, Olivier Taboureau, Hans Bräuner-Osborne, Flemming Steen Jørgensen

Journal:

Year:

2010

Language:

english

File:

PDF, 1.71 MB

english, 2010

12

Rational Design, Synthesis, and DNA Binding Properties of Novel Sequence-Selective Peptidyl Congeners of Ametantrone

Alessandra Gianoncelli, Serena Basili, Matteo Scalabrin, Alice Sosic, Stefano Moro, Giuseppe Zagotto, Manlio Palumbo, Nohad Gresh, Barbara Gatto

Journal:

Year:

2010

Language:

english

File:

PDF, 510 KB

english, 2010

13

Design, Synthesis, and Immunosuppressive Activity of New Deoxybenzoin Derivatives

Huan-Qiu Li, Yin Luo, Ran Song, Zi-Lin Li, Tao Yan, Hai-Liang Zhu

Journal:

Year:

2010

Language:

english

File:

PDF, 256 KB

english, 2010

14

Synthesis and Biological Testing of N-Aminoimidazole-Based p38α MAP Kinase Inhibitors

Claudia Bracht, Dominik R. J. Hauser, Verena Schattel, Wolfgang Albrecht, Stefan A. Laufer

Journal:

Year:

2010

Language:

english

File:

PDF, 377 KB

english, 2010

15

Metronidazole–Deoxybenzoin Derivatives as Anti-Helicobacter pylori Agents with Potent Inhibitory Activity against HPE-Induced Interleukin-8

Yin Luo, Huan-Qiu Li, Yang Zhou, Zi-Lin Li, Tao Yan, Hai-Liang Zhu

Journal:

Year:

2010

Language:

english

File:

PDF, 273 KB

english, 2010

16

Cell-Selective, Apoptosis-inducing Rhodium(III) Crown Thiaether Complexes

Ruth Bieda, Mara Dobroschke, Annika Triller, Ingo Ott, Marc Spehr, Ronald Gust, Aram Prokop, William S. Sheldrick

Journal:

Year:

2010

Language:

english

File:

PDF, 578 KB

english, 2010

17

Inhibition Studies of Mycobacterium tuberculosis Salicylate Synthase (MbtI)

Alexandra Manos-Turvey, Esther M. M. Bulloch, Peter J. Rutledge, Edward N. Baker, J. Shaun Lott, Richard J. Payne

Journal:

Year:

2010

Language:

english

File:

PDF, 497 KB

english, 2010

18

Jostling for Position: Optimizing Linker Location in the Design of Estrogen Receptor-Targeting PROTACs

Kedra Cyrus, Marie Wehenkel, Eun-Young Choi, Hyosung Lee, Hollie Swanson, Kyung-Bo Kim

Journal:

Year:

2010

Language:

english

File:

PDF, 556 KB

english, 2010

19

Novel Therapeutic Targets for Antiarrhythmic Drugs. Edited by George E. Billman.

Ahmed S. Mehanna

Journal:

Year:

2010

Language:

english

File:

PDF, 124 KB

english, 2010

20

ABC Transporters and Multidrug Resistance. Edited by Ahcène Boumendjel, Jean Boutonnat and Jacques Robert.

Journal:

Year:

2010

Language:

english

File:

PDF, 100 KB

english, 2010

21

Preview: ChemMedChem 8/2010

Journal:

Year:

2010

Language:

english

File:

PDF, 73 KB

english, 2010

22

Cover Picture: Inhibition Studies of Mycobacterium tuberculosis Salicylate Synthase (MbtI) (ChemMedChem 7/2010)

Alexandra Manos-Turvey, Esther M. M. Bulloch, Peter J. Rutledge, Edward N. Baker, J. Shaun Lott, Richard J. Payne

Journal:

Year:

2010

Language:

english

File:

PDF, 930 KB

english, 2010

23

Inside Cover: Synthesis and Biological Testing of N-Aminoimidazole-Based p38α MAP Kinase Inhibitors (ChemMedChem 7/2010)

Claudia Bracht, Dominik R. J. Hauser, Verena Schattel, Wolfgang Albrecht, Stefan A. Laufer

Journal:

Year:

2010

File:

PDF, 552 KB

2010

24

Graphical Abstract: ChemMedChem 7/2010

Journal:

Year:

2010

Language:

english

File:

PDF, 1023 KB

english, 2010

25

Spotlights on our sister journals: ChemMedChem 7/2010

Journal:

Year:

2010

Language:

english

File:

PDF, 772 KB

english, 2010