Volume 6; Issue 5

Main
ChemMedChem
Volume 6; Issue 5

ChemMedChem

Volume 6; Issue 5

1

Benzyl and Naphthalene Methylphosphonic Acid Inhibitors of Autotaxin with Anti-invasive and Anti-metastatic Activity

Renuka Gupte, Dr. Renukadevi Patil, Dr. Jianxiong Liu, Dr. Yaohong Wang, Dr. Sue C. Lee, Dr. Yuko Fujiwara, James Fells, Dr. Alyssa L. Bolen, Dr. Karin Emmons-Thompson, Prof. C. Ryan Yates, Dr. Anjaih

Journal:

Year:

2011

Language:

english

File:

PDF, 596 KB

english, 2011

2

Biomarkers in Drug Development: A Handbook of Practice, Application, and Strategy. Edited by Michael R Bleavins, Claudio Carini, Mallé Jurima-Romet and Ramin Rahbari.

Dr. Richard Hargreaves

Journal:

Year:

2011

Language:

english

File:

PDF, 122 KB

english, 2011

3

Emerging Drugs and Targets for Alzheimer's Disease (two volumes). Edited by Ana Martinez.

Professor Harry LeVine

Journal:

Year:

2011

Language:

english

File:

PDF, 104 KB

english, 2011

4

Discovery and Development of Thiazolo[3,2-a]pyrimidinone Derivatives as General Inhibitors of Bcl-2 Family Proteins

Bingcheng Zhou, Dr. Xun Li, Dr. Yan Li, Yaochun Xu, Zhengxi Zhang, Mi Zhou, Dr. Xinglong Zhang, Dr. Zhen Liu, Prof. Jiahai Zhou, Prof. Chunyang Cao, Prof. Biao Yu, Prof. Renxiao Wang

Journal:

Year:

2011

Language:

english

File:

PDF, 1.01 MB

english, 2011

5

Discovery and Biological Activity of 6BrCaQ as an Inhibitor of the Hsp90 Protein Folding Machinery

Dr. Davide Audisio, Dr. Samir Messaoudi, Lukasz Cegielkowski, Prof. Jean-François Peyrat, Prof. Jean-Daniel Brion, Dr. Délphine Methy-Gonnot, Dr. Christine Radanyi, Dr. Jack-Michel Renoir, Dr. Mouâd A

Journal:

Year:

2011

Language:

english

File:

PDF, 607 KB

english, 2011

6

Identification and Characterization of Small-Molecule Inducers of Fetal Hemoglobin

Dr. Tae-gyu Nam, Dr. Jongkook Lee, Dr. John R. Walker, Dr. Achim Brinker, Dr. Charles Y. Cho, Prof. Peter G. Schultz

Journal:

Year:

2011

Language:

english

File:

PDF, 286 KB

english, 2011

7

Design, Synthesis, and Pharmacological Characterization of Novel Spirocyclic Quinuclidinyl-Δ2-Isoxazoline Derivatives as Potent and Selective Agonists of α7 Nicotinic Acetylcholine Receptors

Dr. Clelia Dallanoce, Dr. Pietro Magrone, Dr. Carlo Matera, Dr. Fabio Frigerio, Dr. Giovanni Grazioso, Prof. Marco De Amici, Prof. Sergio Fucile, Dr. Vanessa Piccari, Prof. Karla Frydenvang, Dr. Luca

Journal:

Year:

2011

Language:

english

File:

PDF, 640 KB

english, 2011

8

New Huprine Derivatives Functionalized at Position 9 as Highly Potent Acetylcholinesterase Inhibitors

Dr. Cyril Ronco, Dr. Richard Foucault, Emilie Gillon, Dr. Pierre Bohn, Dr. Florian Nachon, Dr. Ludovic Jean, Prof. Pierre-Yves Renard

Journal:

Year:

2011

Language:

english

File:

PDF, 537 KB

english, 2011

9

Design, Synthesis, and in vitro Antifungal Activity of 1-[(4-Substituted-benzyl)methylamino]-2-(2,4-difluorophenyl)-3-(1H-1,2,4-triazol-1-yl)propan-2-ols

Dr. Rémi Guillon, Dr. Fabrice Pagniez, Dr. Francis Giraud, Damien Crépin, Carine Picot, Prof. Marc Le Borgne, Florent Morio, Prof. Muriel Duflos, Dr. Cédric Logé, Prof. Patrice Le Pape

Journal:

Year:

2011

Language:

english

File:

PDF, 365 KB

english, 2011

10

Synthesis and Investigations on the Oxidative Degradation of C3/C5-Alkyl-1,2,4-triarylpyrroles as Ligands for the Estrogen Receptor

Dr. Anja Schäfer, Anja Wellner, Prof. Dr. Ronald Gust

Journal:

Year:

2011

Language:

english

File:

PDF, 414 KB

english, 2011

11

Evaluation of Readily Accessible Azoles as Mimics of the Aromatic Ring of D-Phenylalanine in the Turn Region of Gramicidin S

Dr. Matthijs van der Knaap, Lianne T. Lageveen, Prof. Dr. Henk J. Busscher, Roos Mars-Groenendijk, Dr. Daan Noort, Dr. José M. Otero, Dr. Antonio L. Llamas-Saiz, Dr. Mark J. van Raaij, Prof. Dr. Gijsb

Journal:

Year:

2011

Language:

english

File:

PDF, 645 KB

english, 2011

12

Azamacrocyclic Metal Complexes as CXCR4 Antagonists

Tomohiro Tanaka, Dr. Tetsuo Narumi, Taro Ozaki, Akira Sohma, Nami Ohashi, Chie Hashimoto, Kyoko Itotani, Dr. Wataru Nomura, Dr. Tsutomu Murakami, Prof. Naoki Yamamoto, Prof. Hirokazu Tamamura

Journal:

Year:

2011

Language:

english

File:

PDF, 305 KB

english, 2011

13

The Discovery of MMP7 Inhibitors Exploiting a Novel Selectivity Trigger

Dr. Karl Edman, Dr. Mark Furber, Paul Hemsley, Cristian Johansson, Dr. Garry Pairaudeau, Dr. Jens Petersen, Dr. Michael Stocks, Dr. Anu Tervo, Dr. Alison Ward, Dr. Edward Wells, Lisa Wissler

Journal:

Year:

2011

Language:

english

File:

PDF, 855 KB

english, 2011

14

Synthesis and Biological Evaluation of 6-Substituted 5-Alkyl-2-(phenylaminocarbonylmethylthio)pyrimidin-4(3H)-ones as Potent HIV-1 NNRTIs

Dr. Mingyan Yu, Zhenyu Li, Shuai Liu, Erkang Fan, Prof. Dr. Christophe Pannecouque, Prof. Dr. Erik De Clercq, Prof. Dr. Xinyong Liu

Journal:

Year:

2011

Language:

english

File:

PDF, 421 KB

english, 2011

15

Oxidatively Activated DNA-Modifying Agents for Selective Cytotoxicity

Guorui Li, Tiffany Bell, Prof. Edward J. Merino

Journal:

Year:

2011

Language:

english

File:

PDF, 464 KB

english, 2011

16

Structure-Based Repurposing of FDA-Approved Drugs as TNF-α Inhibitors

Dr. Chung-Hang Leung, Daniel Shiu-Hin Chan, Maria Hiu-Tung Kwan, Zhen Cheng, Chun-Yuen Wong, Guo-Yuan Zhu, Wang-Fun Fong, Dr. Dik-Lung Ma

Journal:

Year:

2011

Language:

english

File:

PDF, 514 KB

english, 2011

17

Synthesis and Antitumor Evaluation of Nitrovinyl Biphenyls: Anticancer Agents Based on Allocolchicines

Dr. Nishant Jain, Divya Yada, Thokhir B. Shaik, Galanki Vasantha, P. Surendra Reddy, Dr. Shasi V. Kalivendi, Dr. B. Sreedhar

Journal:

Year:

2011

Language:

english

File:

PDF, 570 KB

english, 2011

18

Synthesis, Structure, and Biological Activity of des-Side Chain Analogues of 1α,25-Dihydroxyvitamin D3 with Substituents at C18

Dr. Lieve Verlinden, Prof. Annemieke Verstuyf, Dr. Guy Eelen, Prof. Roger Bouillon, Dr. Paloma Ordóñez-Morán, Dr. María Jesús Larriba, Prof. Alberto Muñoz, Dr. Natacha Rochel, Dr. Yoshiteru Sato, Dr.

Journal:

Year:

2011

Language:

english

File:

PDF, 375 KB

english, 2011

19

Inhibition of Histone Demethylases by 4-Carboxy-2,2′-Bipyridyl Compounds

Kai-Hsuan Chang, Dr. Oliver N. F. King, Dr. Anthony Tumber, Dr. Esther C. Y. Woon, Dr. Tom D. Heightman, Dr. Michael A. McDonough, Prof. Dr. Christopher J. Schofield, Dr. Nathan R. Rose

Journal:

Year:

2011

Language:

english

File:

PDF, 711 KB

english, 2011

20

Glycosyloxyamine Neoglycosylation: A Model Study Using Calicheamicin

Dr. Randal D. Goff, Dr. Shanteri Singh, Prof. Jon S. Thorson

Journal:

Year:

2011

Language:

english

File:

PDF, 232 KB

english, 2011

21

Mechanism of Cytotoxicity and Cellular Uptake of Lipophilic Inert Dinuclear Polypyridylruthenium(II) Complexes

Michelle J. Pisani, Phillip D. Fromm, Dr. Yanyan Mulyana, Dr. Ronald J. Clarke, Prof. Heinrich Körner, Prof. Kirsten Heimann, Prof. J. Grant Collins, Prof. F. Richard Keene

Journal:

Year:

2011

Language:

english

File:

PDF, 574 KB

english, 2011

22

Development of Intravascular Contrast Agents for MRI Using Gadolinium Chelates

Krisada Kittigowittana, Dr. Chang-Tong Yang, Dr. Wai Ching Cheah, Dr. Kai-Hsiang Chuang, Chew-Yuan Tuang, Prof. Young-Tae Chang, Dr. Xavier Golay, Prof. Roderick W. Bates

Journal:

Year:

2011

Language:

english

File:

PDF, 326 KB

english, 2011

23

E. Giralt Lledó

Journal:

Year:

2011

Language:

english

File:

PDF, 142 KB

english, 2011

24

Cover Picture: Discovery and Biological Activity of 6BrCaQ as an Inhibitor of the Hsp90 Protein Folding Machinery (ChemMedChem 5/2011)

Dr. Davide Audisio, Dr. Samir Messaoudi, Lukasz Cegielkowski, Prof. Jean-François Peyrat, Prof. Jean-Daniel Brion, Dr. Délphine Methy-Gonnot, Dr. Christine Radanyi, Dr. Jack-Michel Renoir, Dr. Mouâd A

Journal:

Year:

2011

Language:

english

File:

PDF, 1.43 MB

english, 2011

25

Inside Cover: Mechanism of Cytotoxicity and Cellular Uptake of Lipophilic Inert Dinuclear Polypyridylruthenium(II) Complexes (ChemMedChem 5/2011)

Michelle J. Pisani, Phillip D. Fromm, Dr. Yanyan Mulyana, Dr. Ronald J. Clarke, Prof. Heinrich Körner, Prof. Kirsten Heimann, Prof. J. Grant Collins, Prof. F. Richard Keene

Journal:

Year:

2011

Language:

english

File:

PDF, 435 KB

english, 2011

26

Graphical Abstract: ChemMedChem 5/2011

Journal:

Year:

2011

Language:

english

File:

PDF, 1.31 MB

english, 2011

27

Corrigendum: Discovery of Isoerianin Analogues as Promising Anticancer Agents

Dr. Samir Messaoudi, Dr. Abdallah Hamze, Dr. Olivier Provot, Bret Tréguier, Dr. Jordi Rodrigo De Losada, Dr. Jérôme Bignon, Dr. Jian-Miao Liu, Dr. Joanna Wdzieczak-Bakala, Sylviane Thoret, Dr. Joëlle

Journal:

Year:

2011

File:

PDF, 60 KB

2011

28

Spotlights on our sister journals: ChemMedChem 5/2011

Journal:

Year:

2011

Language:

english

File:

PDF, 771 KB

english, 2011

29

Preview: ChemMedChem 6/2011

Journal:

Year:

2011

Language:

english

File:

PDF, 70 KB

english, 2011

To build up a library is to create a life. It’s never just a random collection of books.

— Carlos María Domínguez

Official channel

Z-Library Desktop Launcher

Tor version

Z-Library

Z-Library Since 2009 support@z-lib.do

EnglishРусскийEspañolItalianoελληνικάاللغة العربيةBahasa IndonesiaBahasa Malaysiaहिन्दीDeutschFrançaisPortuguêsУкраїнськаPolski中文繁體中文日本語Tiếng ViệtAzərbaycan DiliՀայոց լեզուภาษาไทยTürk Diliქართველიবাংলাپښتوతెలుగుاردو한국어SrpskiБългарски