Volume 7; Issue 12

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ChemMedChem
Volume 7; Issue 12

ChemMedChem

Volume 7; Issue 12

1

Kinetic Template-Guided Tethering of Fragments

Rebecca H. Nonoo, Prof. Alan Armstrong, Dr. David J. Mann

Journal:

Year:

2012

Language:

english

File:

PDF, 861 KB

english, 2012

2

Synthesis and Biological Evaluation of N -Substituted Noscapine Analogues

DeBono, Aaron J., Xie, Jin Han, Ventura, Sabatino, Pouton, Colin W., Capuano, Ben, Scammells, Peter J.

Journal:

Year:

2012

Language:

english

File:

PDF, 653 KB

english, 2012

3

Effect of Oxime Ether Incorporation in Acyl Indole Derivatives on PPAR Subtype Selectivity

Le Naour, Morgan, Leclerc, Veronique, Farce, Amaury, Caignard, Daniel-Henri, Hennuyer, Nathalie, Staels, Bart, Audinot-Bouchez, Valérie, Boutin, Jean-Albert, Lonchampt, Michel, Dacquet, Catherine, Kto

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Year:

2012

Language:

english

File:

PDF, 926 KB

english, 2012

4

Camptothecin-7-yl-methanthiole: Semisynthesis and Biological Evaluation

Christodoulou, Michael S., Zunino, Franco, Zuco, Valentina, Borrelli, Stella, Comi, Daniela, Fontana, Gabriele, Martinelli, Marisa, Lorens, James B., Evensen, Lasse, Sironi, Maurizio, Pieraccini, Stef

Journal:

Year:

2012

Language:

english

File:

PDF, 1.58 MB

english, 2012

5

Recent Advances in the Research of Heterocyclic Compounds as Antitubercular Agents

Yan, Mi, Ma, Shutao

Journal:

Year:

2012

Language:

english

File:

PDF, 479 KB

english, 2012

6

Two-Photon Fluorescent Imaging of Myelination in the Spinal Cord

Condie, Allison G., Gerson, Stanton L., Miller, Robert H., Wang, Yanming

Journal:

Year:

2012

Language:

english

File:

PDF, 1.87 MB

english, 2012

7

Discovery of Depsides and Depsidones from Lichen as Potent Inhibitors of Microsomal Prostaglandin E2 Synthase-1 Using Pharmacophore Models

Bauer, Julia, Waltenberger, Birgit, Noha, Stefan M., Schuster, Daniela, Rollinger, Judith M., Boustie, Joel, Chollet, Marylene, Stuppner, Hermann, Werz, Oliver

Journal:

Year:

2012

Language:

english

File:

PDF, 376 KB

english, 2012

8

Aromatic Core Extension in the Series of N-Cyclic Bay-Substituted Perylene G-Quadruplex Ligands: Increased Telomere Damage, Antitumor Activity, and Strong Selectivity for Neoplastic over Healthy Cells

Franceschin, Marco, Rizzo, Angela, Casagrande, Valentina, Salvati, Erica, Alvino, Antonello, Altieri, Alessandro, Ciammaichella, Alina, Iachettini, Sara, Leonetti, Carlo, Ortaggi, Giancarlo, Porru, Ma

Journal:

Year:

2012

Language:

english

File:

PDF, 1.16 MB

english, 2012

9

Directed Modulation of Protein Kinase C Isozyme Selectivity with Bisubstrate-Based Inhibitors

van Wandelen, Loek T. M., van Ameijde, Jeroen, Mady, Ahmed S. A., Wammes, Angelique E. M., Bode, Alois, Poot, Alex J., Ruijtenbeek, Rob, Liskamp, Rob M. J.

Journal:

Year:

2012

Language:

english

File:

PDF, 500 KB

english, 2012

10

Stable Synthetic Bacteriochlorins for Photodynamic Therapy: Role of Dicyano Peripheral Groups, Central Metal Substitution (2H, Zn, Pd), and Cremophor EL Delivery

Huang, Ying-Ying, Balasubramanian, Thiagarajan, Yang, Eunkyung, Luo, Dianzhong, Diers, James R., Bocian, David F., Lindsey, Jonathan S., Holten, Dewey, Hamblin, Michael R.

Journal:

Year:

2012

Language:

english

File:

PDF, 2.68 MB

english, 2012

11

Structural Exploration of (3 S ,6 S )-6-Benzhydryl- N -benzyltetrahydro-2 H -pyran-3-amine Analogues: Identification of Potent Triple Monoamine Reuptake Inhibitors as Potential Antidepressants

Santra, Soumava, Gogoi, Sanjib, Gopishetty, Bhaskar, Antonio, Tamara, Zhen, Juan, Reith, Maarten E. A., Dutta, Aloke K.

Journal:

Year:

2012

Language:

english

File:

PDF, 321 KB

english, 2012

12

A DNA Methyltransferase Modulator Inspired by Peyssonenyne Natural Product Structures

García-Domínguez, Patricia, Weiss, Mélanie, Lepore, Ilaria, Álvarez, Rosana, Altucci, Lucia, Gronemeyer, Hinrich, de Lera, Ángel R.

Journal:

Year:

2012

Language:

english

File:

PDF, 705 KB

english, 2012

13

Receptor-Based Virtual Screening and Biological Characterization of Human Apurinic/Apyrimidinic Endonuclease (Ape1) Inhibitors

Ruiz, Federico M., Francis, Sandrea M., Tintoré, Maria, Ferreira, Rubén, Gil-Redondo, Rubén, Morreale, Antonio, Ortiz, Ángel R., Eritja, Ramon, Fàbrega, Carmen

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Year:

2012

Language:

english

File:

PDF, 1.30 MB

english, 2012

14

Interactions between Artemisinins and other Antimalarial Drugs in Relation to the Cofactor Model-A Unifying Proposal for Drug Action

Haynes, Richard K., Cheu, Kwan-Wing, Chan, Ho-Wai, Wong, Ho-Ning, Li, Ka-Yan, Tang, Maggie Mei-Ki, Chen, Min-Jiao, Guo, Zu-Feng, Guo, Zhi-Hong, Sinniah, Kumar, Witte, Amanda B., Coghi, Paolo, Monti, D

Journal:

Year:

2012

Language:

english

File:

PDF, 2.98 MB

english, 2012

15

Lead Optimization of Thiazolo[5,4- c ]piperidines: 3-Cyclobutoxy Linker as a Key Spacer for H 3 R Inverse Agonists

Provins, Laurent, Denonne, Frédéric, Célanire, Sylvain, Christophe, Bernard, Defays, Sabine, Delaunoy, Christel, Delporte, Marie-Laure, Demaude, Thierry, Durieu, Véronique, Gillard, Michel, Hubert, De

Journal:

Year:

2012

Language:

english

File:

PDF, 370 KB

english, 2012

16

Protein and Peptide Mass Spectrometry in Drug Discovery . Edited by Michael L. Gross, Guodong Chen and Birendra N. Pramanik

Jungblut, Peter R.

Journal:

Year:

2012

Language:

english

File:

PDF, 105 KB

english, 2012

17

Identification of Small Molecules that Interfere with H1N1 Influenza A Viral Replication

Bottini, Angel, De, Surya K., Baaten, Bas J. G., Wu, Bainan, Barile, Elisa, Soonthornvacharin, Stephen, Stebbins, John L., Bradley, Linda M., Chanda, Sumit K., Pellecchia, Maurizio

Journal:

Year:

2012

Language:

english

File:

PDF, 848 KB

english, 2012

18

Alpine Drug Discovery Summit: 10th Swiss Course on Medicinal Chemistry

Müller, Gerhard, Ernst, Beat

Journal:

Year:

2012

Language:

english

File:

PDF, 1.64 MB

english, 2012

19

Corrigendum: Designing Multitarget Anti-inflammatory Agents: Chemical Modulation of the Lumiracoxib Structure toward Dual Thromboxane Antagonists-COX-2 Inhibitors

Bertinaria, Massimo, Shaikh, Mohammed Abrar Abdul Gaffar, Buccellati, Carola, Cena, Clara, Rolando, Barbara, Lazzarato, Loretta, Fruttero, Roberta, Gasco, Alberto, Hoxha, Malvina, Capra, Valérie, Sala

Journal:

Year:

2012

File:

PDF, 126 KB

2012

20

Cover Picture: A DNA Methyltransferase Modulator Inspired by Peyssonenyne Natural Product Structures (ChemMedChem 12/2012)

García-Domínguez, Patricia, Weiss, Mélanie, Lepore, Ilaria, Álvarez, Rosana, Altucci, Lucia, Gronemeyer, Hinrich, de Lera, Ángel R.

Journal:

Year:

2012

Language:

english

File:

PDF, 1.12 MB

english, 2012

21

Inside Cover: Directed Modulation of Protein Kinase C Isozyme Selectivity with Bisubstrate-Based Inhibitors (ChemMedChem 12/2012)

van Wandelen, Loek T. M., van Ameijde, Jeroen, Mady, Ahmed S. A., Wammes, Angelique E. M., Bode, Alois, Poot, Alex J., Ruijtenbeek, Rob, Liskamp, Rob M. J.

Journal:

Year:

2012

File:

PDF, 999 KB

2012

22

Graphical Abstract: ChemMedChem 12/2012

Journal:

Year:

2012

Language:

english

File:

PDF, 3.73 MB

english, 2012

23

Spotlights on our sister journals: ChemMedChem 12/2012

Journal:

Year:

2012

Language:

english

File:

PDF, 1.83 MB

english, 2012

24

Back Cover: Two-Photon Fluorescent Imaging of Myelination in the Spinal Cord (ChemMedChem 12/2012)

Condie, Allison G., Gerson, Stanton L., Miller, Robert H., Wang, Yanming

Journal:

Year:

2012

File:

PDF, 1.71 MB

2012