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Volume 8; Issue 9
Main
ChemMedChem
Volume 8; Issue 9
ChemMedChem
Volume 8; Issue 9
1
Overcoming the Limitations of Fragment Merging: Rescuing a Strained Merged Fragment Series Targeting Mycobacterium tuberculosis CYP121
Hudson, Sean A.
,
Surade, Sachin
,
Coyne, Anthony G.
,
McLean, Kirsty J.
,
Leys, David
,
Munro, Andrew W.
,
Abell, Chris
Journal:
ChemMedChem
Year:
2013
Language:
english
File:
PDF, 1.82 MB
Your tags:
english, 2013
2
Synthesis and Biological Evaluation of 2-Arylamino-5- (3′-Indolyl)-1,3,4-Oxadiazoles as Potent Cytotoxic Agents
Tantak, Mukund P
,
Kumar, Anil
,
Noel, Brett
,
Shah, Kavita
,
Kumar, Dalip
Journal:
ChemMedChem
Year:
2013
Language:
english
File:
PDF, 457 KB
Your tags:
english, 2013
3
6-Aryl and Heterocycle Quinazoline Derivatives as Potent EGFR Inhibitors with Improved Activity toward Gefitinib-Sensitive and -Resistant Tumor Cell Lines
Hamed, Mostafa M.
,
Abou El Ella, Dalal A.
,
Keeton, Adam B.
,
Piazza, Gary A.
,
Abadi, Ashraf H.
,
Hartmann, Rolf W.
,
Engel, Matthias
Journal:
ChemMedChem
Year:
2013
Language:
english
File:
PDF, 719 KB
Your tags:
english, 2013
4
Probing the S1′ Site for the Identification of Non-Zinc-Binding MMP-2 Inhibitors
Di Pizio, Antonella
,
Laghezza, Antonio
,
Tortorella, Paolo
,
Agamennone, Mariangela
Journal:
ChemMedChem
Year:
2013
Language:
english
File:
PDF, 741 KB
Your tags:
english, 2013
5
The Cell’s Nucleolus: an Emerging Target for Chemotherapeutic Intervention
Pickard, Amanda J.
,
Bierbach, Ulrich
Journal:
ChemMedChem
Year:
2013
Language:
english
File:
PDF, 1.07 MB
Your tags:
english, 2013
6
An Endoperoxide-Based Hybrid Approach to Deliver Falcipain Inhibitors Inside Malaria Parasites
Oliveira, Rudi
,
Newton, Ana S.
,
Guedes, Rita C.
,
Miranda, Daniela
,
Amewu, Richard K.
,
Srivastava, Abhishek
,
Gut, Jiri
,
Rosenthal, Philip J.
,
O'Neill, Paul M.
,
Ward, Stephen A.
,
Lopes, Francisca
,
Morei
Journal:
ChemMedChem
Year:
2013
Language:
english
File:
PDF, 739 KB
Your tags:
english, 2013
7
Thiuram Disulfides as Pseudo-irreversible Inhibitors of Lymphoid Tyrosine Phosphatase
Kulkarni, Rhushikesh A.
,
Stanford, Stephanie M.
,
Vellore, Nadeem A.
,
Krishnamurthy, Divya
,
Bliss, Matthew R.
,
Baron, Riccardo
,
Bottini, Nunzio
,
Barrios, Amy M.
Journal:
ChemMedChem
Year:
2013
Language:
english
File:
PDF, 831 KB
Your tags:
english, 2013
8
Back Cover: Strategic Targeting of Multiple Water-Mediated Interactions: A Concise and Rational Structure-Based Design Approach to Potent and Selective MMP-13 Inhibitors (ChemMedChem 9/2013)
Fischer, Thomas
,
Riedl, Rainer
Journal:
ChemMedChem
Year:
2013
File:
PDF, 1.05 MB
Your tags:
2013
9
Strategic Targeting of Multiple Water-Mediated Interactions: A Concise and Rational Structure-Based Design Approach to Potent and Selective MMP-13 Inhibitors
Fischer, Thomas
,
Riedl, Rainer
Journal:
ChemMedChem
Year:
2013
Language:
english
File:
PDF, 1.26 MB
Your tags:
english, 2013
10
Rise of the Selective Inhibitors of Anti-Apoptotic Bcl-2 Family Proteins
Han, Li
,
Wang, Renxiao
Journal:
ChemMedChem
Year:
2013
Language:
english
File:
PDF, 983 KB
Your tags:
english, 2013
11
Synthesis and Biological Evaluation of N-Substituted Sophocarpinic Acid Derivatives as Coxsackievirus B3 Inhibitors
Gao, Li-Mei
,
Tang, Sheng
,
Wang, Yan-Xiang
,
Gao, Rong-Mei
,
Zhang, Xin
,
Peng, Zong-Gen
,
Li, Jian-Rui
,
Jiang, Jian-Dong
,
Li, Yu-Huan
,
Song, Dan-Qing
Journal:
ChemMedChem
Year:
2013
Language:
english
File:
PDF, 513 KB
Your tags:
english, 2013
12
Cover Picture: Probing the S1′ Site for the Identification of Non-Zinc-Binding MMP-2 Inhibitors (ChemMedChem 9/2013)
Pizio, Antonella Di
,
Laghezza, Antonio
,
Tortorella, Paolo
,
Agamennone, Mariangela
Journal:
ChemMedChem
Year:
2013
Language:
english
File:
PDF, 651 KB
Your tags:
english, 2013
13
Rational Design of Resorcylic Acid Lactone Analogues as Covalent MNK1/2 Kinase Inhibitors by Tuning the Reactivity of an Enamide Michael Acceptor
Xu, Jin
,
Chen, Anqi
,
Joy, Joma
,
Xavier, Vanessa Joanne
,
Ong, Esther H. Q.
,
Hill, Jeffrey
,
Chai, Christina L. L.
Journal:
ChemMedChem
Year:
2013
Language:
english
File:
PDF, 954 KB
Your tags:
english, 2013
14
Zopolrestat as a Human Glyoxalase I Inhibitor and Its Structural Basis
Zhai, Jing
,
Zhang, Hong
,
Zhang, Ligping
,
Zhao, Yining
,
Chen, Sangke
,
Chen, Yunyun
,
Peng, Xinyu
,
Li, Qing
,
Yuan, Minggui
,
Hu, Xiaopeng
Journal:
ChemMedChem
Year:
2013
Language:
english
File:
PDF, 610 KB
Your tags:
english, 2013
15
Inside Cover: A Parallel Semisynthetic Approach for Structure-Activity Relationship Studies of Peptide YY (ChemMedChem 9/2013)
Albertsen, Louise
,
Østergaard, Søren
,
Paulsson, Johan F.
,
Norrild, Jens Chr.
,
Strømgaard, Kristian
Journal:
ChemMedChem
Year:
2013
File:
PDF, 949 KB
Your tags:
2013
16
Spotlights on our sister journals: ChemMedChem 9/2013
Journal:
ChemMedChem
Year:
2013
Language:
english
File:
PDF, 1.49 MB
Your tags:
english, 2013
17
cis -[Pt II (1 R ,2 R -DACH)(3-acetoxy-1,1-cyclobutanedicarboxylato)], a Water-Soluble, Oxalate-Free and Stable Analogue of Oxaliplatin: Synthesis, Characterization, and Biological Evaluations
Liu, Weiping
,
Ye, Qingsong
,
Jiang, Jing
,
Lou, Liguang
,
Xu, Yongping
,
Xie, Chengying
,
Xie, Mingjin
Journal:
ChemMedChem
Year:
2013
Language:
english
File:
PDF, 368 KB
Your tags:
english, 2013
18
Structure-Activity Relationship Studies of Pyrrolone Antimalarial Agents
Murugesan, Dinakaran
,
Kaiser, Marcel
,
White, Karen L.
,
Norval, Suzanne
,
Riley, Jennifer
,
Wyatt, Paul G.
,
Charman, Susan A.
,
Read, Kevin D.
,
Yeates, Clive
,
Gilbert, Ian H.
Journal:
ChemMedChem
Year:
2013
Language:
english
File:
PDF, 337 KB
Your tags:
english, 2013
19
Graphical Abstract: ChemMedChem 9/2013
Journal:
ChemMedChem
Year:
2013
Language:
english
File:
PDF, 3.07 MB
Your tags:
english, 2013
20
Chemical, Pharmacological, and in vitro Metabolic Stability Studies on Enantiomerically Pure RC-33 Compounds: Promising Neuroprotective Agents Acting as σ 1 Receptor Agonists
Rossi, Daniela
,
Pedrali, Alice
,
Gaggeri, Raffaella
,
Marra, Annamaria
,
Pignataro, Luca
,
Laurini, Erik
,
Dal Col, Valentina
,
Fermeglia, Maurizio
,
Pricl, Sabrina
,
Schepmann, Dirk
,
Wünsch, Bernhard
,
Pevian
Journal:
ChemMedChem
Year:
2013
Language:
english
File:
PDF, 1.35 MB
Your tags:
english, 2013
21
Synthesis and in vitro Evaluation of West Nile Virus Protease Inhibitors Based on the 1,3,4,5-Tetrasubstituted 1 H -Pyrrol-2(5 H )-one Scaffold
Gao, Yaojun
,
Samanta, Sanjay
,
Cui, Taian
,
Lam, Yulin
Journal:
ChemMedChem
Year:
2013
Language:
english
File:
PDF, 579 KB
Your tags:
english, 2013
22
A Parallel Semisynthetic Approach for Structure-Activity Relationship Studies of Peptide YY
Albertsen, Louise
,
Østergaard, Søren
,
Paulsson, Johan F.
,
Norrild, Jens Chr.
,
Strømgaard, Kristian
Journal:
ChemMedChem
Year:
2013
Language:
english
File:
PDF, 656 KB
Your tags:
english, 2013
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