Volume 9; Issue 1

Main
ChemMedChem
Volume 9; Issue 1

ChemMedChem

Volume 9; Issue 1

1

Tetrahydroisoquinolinone-Based Steroidomimetic and Chimeric Microtubule Disruptors

Leese, Mathew P., Jourdan, Fabrice L., Major, Meriel R., Dohle, Wolfgang, Hamel, Ernest, Ferrandis, Eric, Fiore, Ann, Kasprzyk, Philip G., Potter, Barry V. L.

Journal:

Year:

2014

Language:

english

File:

PDF, 927 KB

english, 2014

2

Heterocyclic Chemistry in Drug Discovery . Edited by Jie Jack Li

Camarasa, María-José

Journal:

Year:

2014

Language:

english

File:

PDF, 168 KB

english, 2014

3

Synthesis and Biological Evaluation of Biphenyl Amides That Modulate the US28 Receptor

Kralj, Ana, Kurt, Elif, Tschammer, Nuska, Heinrich, Markus R.

Journal:

Year:

2014

Language:

english

File:

PDF, 743 KB

english, 2014

4

Synthesis, Characterization, and Antimicrobial Activity of Silver(I) and Copper(II) Complexes of Phosphate Derivatives of Pyridine And Benzimidazole

Kalinowska-Lis, Urszula, Szewczyk, Eligia M., Chęcińska, Lilianna, Wojciechowski, Jakub M., Wolf, Wojciech M., Ochocki, Justyn

Journal:

Year:

2014

Language:

english

File:

PDF, 931 KB

english, 2014

5

Discovery of 7-Aryl-Substituted (1,5-Naphthyridin-4-yl)ureas as Aurora Kinase Inhibitors

Defaux, Julien, Antoine, Maud, Le Borgne, Marc, Schuster, Tilmann, Seipelt, Irene, Aicher, Babette, Teifel, Michael, Günther, Eckhard, Gerlach, Matthias, Marchand, Pascal

Journal:

Year:

2014

Language:

english

File:

PDF, 443 KB

english, 2014

6

Structural Design, Synthesis and Structure-Activity Relationships of Thiazolidinones with Enhanced Anti- Trypanosoma cruzi Activity

Moreira, Diogo Rodrigo Magalhães, Lima Leite, Ana Cristina, Cardoso, Marcos Verissimo Oliveira, Srivastava, Rajendra Mohan, Hernandes, Marcelo Zaldini, Rabello, Marcelo Montenegro, da Cruz, Luana Fari

Journal:

Year:

2014

Language:

english

File:

PDF, 1.55 MB

english, 2014

7

Kinetic Properties of Carbohydrate-Lectin Interactions: FimH Antagonists

Scharenberg, Meike, Jiang, Xiaohua, Pang, Lijuan, Navarra, Giulio, Rabbani, Said, Binder, Florian, Schwardt, Oliver, Ernst, Beat

Journal:

Year:

2014

Language:

english

File:

PDF, 825 KB

english, 2014

8

Synthesis and Biological Evaluation of Benzo[ b ]furans as Inhibitors of Tubulin Polymerization and Inducers of Apoptosis

Kamal, Ahmed, Reddy, N. V. Subba, Nayak, V. Lakshma, Reddy, V. Saidi, Prasad, B., Nimbarte, Vijaykumar D., Srinivasulu, Vunnam, Vishnuvardhan, M. V. P. S., Reddy, C. Suresh

Journal:

Year:

2014

Language:

english

File:

PDF, 1.28 MB

english, 2014

9

Inhibition of Hypoxia-Induced Gene Transcription by Substituted Pyrazolyl Oxadiazoles: Initial Lead Generation and Structure-Activity Relationships

Härter, Michael, Thierauch, Karl-Heinz, Boyer, Stephen, Bhargava, Ajay, Ellinghaus, Peter, Beck, Hartmut, Greschat-Schade, Susanne, Hess-Stumpp, Holger, Unterschemmann, Kerstin

Journal:

Year:

2014

Language:

english

File:

PDF, 344 KB

english, 2014

10

Lead Evaluation of Tetrahydroquinolines as Nonsteroidal Selective Androgen Receptor Modulators for the Treatment of Osteoporosis

Nagata, Naoya, Furuya, Kazuyuki, Oguro, Nao, Nishiyama, Daisuke, Kawai, Kentaro, Yamamoto, Noriko, Ohyabu, Yuki, Satsukawa, Masahiro, Miyakawa, Motonori

Journal:

Year:

2014

Language:

english

File:

PDF, 1.33 MB

english, 2014

11

The Fight against the Influenza A Virus H1N1: Synthesis, Molecular Modeling, and Biological Evaluation of Benzofurazan Derivatives as Viral RNA Polymerase Inhibitors

Pagano, Mafalda, Castagnolo, Daniele, Bernardini, Martina, Fallacara, Anna Lucia, Laurenzana, Ilaria, Deodato, Davide, Kessler, Ulrich, Pilger, Beatrice, Stergiou, Lilli, Strunze, Stephan, Tintori, Cr

Journal:

Year:

2014

Language:

english

File:

PDF, 829 KB

english, 2014

12

PET Radiotracers for Imaging P-glycoprotein: The Challenge for Early Diagnosis in AD

Leopoldo, Marcello, Contino, Marialessandra, Berardi, Francesco, Perrone, Roberto, Colabufo, Nicola Antonio

Journal:

Year:

2014

Language:

english

File:

PDF, 283 KB

english, 2014

13

Inside Cover: Tailoring Small Molecules for an Allosteric Site on Procaspase-6 (ChemMedChem 1/2014)

Murray, Jeremy, Giannetti, Anthony M., Steffek, Micah, Gibbons, Paul, Hearn, Brian R., Cohen, Frederick, Tam, Christine, Pozniak, Christine, Bravo, Brandon, Lewcock, Joe, Jaishankar, Priyadarshini, Ly

Journal:

Year:

2014

File:

PDF, 1.34 MB

2014

14

Tailoring Small Molecules for an Allosteric Site on Procaspase-6

Murray, Jeremy, Giannetti, Anthony M., Steffek, Micah, Gibbons, Paul, Hearn, Brian R., Cohen, Frederick, Tam, Christine, Pozniak, Christine, Bravo, Brandon, Lewcock, Joe, Jaishankar, Priyadarshini, Ly

Journal:

Year:

2014

Language:

english

File:

PDF, 799 KB

english, 2014

15

Synthesis and Characterization of Glycol Chitosan DNA Nanoparticles for Retinal Gene Delivery

Mitra, Rajendra N., Han, Zongchao, Merwin, Miles, Al Taai, Muhammed, Conley, Shannon M., Naash, Muna I.

Journal:

Year:

2014

Language:

english

File:

PDF, 2.30 MB

english, 2014

16

Drug Discovery Alliances in India-Indications, Targets, and New Chemical Entities

Differding, Edmond

Journal:

Year:

2014

Language:

english

File:

PDF, 508 KB

english, 2014

17

Concise Notice to Authors

Journal:

Year:

2014

Language:

english

File:

PDF, 202 KB

english, 2014

18

Structural Optimization of Berberine as a Synergist to Restore Antifungal Activity of Fluconazole against Drug-Resistant Candida albicans

Liu, Hong, Wang, Liang, Li, Yan, Liu, Jiang, An, Maomao, Zhu, Shaolong, Cao, Yongbing, Jiang, Zhihui, Zhao, Mingzhu, Cai, Zhan, Dai, Li, Ni, Tingjunhong, Liu, Wei, Chen, Simin, Wei, Changqing, Zang, C

Journal:

Year:

2014

Language:

english

File:

PDF, 347 KB

english, 2014

19

Emerging Drugs and Targets for Parkinson’s Disease . Edited by Ana Martinez and Carmen Gil

Müller, Christa E.

Journal:

Year:

2014

Language:

english

File:

PDF, 197 KB

english, 2014

20

Small Wonders: Peptides for Disease Control . Edited by Kanniah Rajasekaran, Jeffrey W. Cary, Jesse M. Jaynes and Emilio Montesinos

Journal:

Year:

2014

Language:

english

File:

PDF, 144 KB

english, 2014

21

Editorial: ChemMedChem 2.0-More Mobile, More Social

Ortúzar, Natalia

Journal:

Year:

2014

Language:

english

File:

PDF, 676 KB

english, 2014

22

Fluorophore-Labeled Cyclooxygenase-2 Inhibitors for the Imaging of Cyclooxygenase-2 Overexpression in Cancer: Synthesis and Biological Studies

Bhardwaj, Atul, Kaur, Jatinder, Wuest, Frank, Knaus, Edward E.

Journal:

Year:

2014

Language:

english

File:

PDF, 1.53 MB

english, 2014

23

Cover Picture: Tetrahydroisoquinolinone-Based Steroidomimetic and Chimeric Microtubule Disruptors (ChemMedChem 1/2014)

Leese, Mathew P., Jourdan, Fabrice L., Major, Meriel R., Dohle, Wolfgang, Hamel, Ernest, Ferrandis, Eric, Fiore, Ann, Kasprzyk, Philip G., Potter, Barry V. L.

Journal:

Year:

2014

Language:

english

File:

PDF, 1.29 MB

english, 2014

24

Graphical Abstract: ChemMedChem 1/2014

Journal:

Year:

2014

Language:

english

File:

PDF, 2.76 MB

english, 2014

25

Spotlights on our sister journals: ChemMedChem 1/2014

Journal:

Year:

2014

Language:

english

File:

PDF, 1.44 MB

english, 2014

26

Target Hopping as a Useful Tool for the Identification of Novel EphA2 Protein-Protein Antagonists

Tognolini, Massimiliano, Incerti, Matteo, Pala, Daniele, Russo, Simonetta, Castelli, Riccardo, Hassan-Mohamed, Iftiin, Giorgio, Carmine, Lodola, Alessio

Journal:

Year:

2014

Language:

english

File:

PDF, 2.00 MB

english, 2014

27

Back Cover: Fluorophore-Labeled Cyclooxygenase-2 Inhibitors for the Imaging of Cyclooxygenase-2 Overexpression in Cancer: Synthesis and Biological Studies (ChemMedChem 1/2014)

Bhardwaj, Atul, Kaur, Jatinder, Wuest, Frank, Knaus, Edward E.

Journal:

Year:

2014

File:

PDF, 1.75 MB

2014

28

New Members of ChemMedChem ′s Editorial and International Advisory Boards

Journal:

Year:

2014

Language:

english

File:

PDF, 1.01 MB

english, 2014

29

Hedgehog Pathway Agonism: Therapeutic Potential and Small-Molecule Development

Hadden, M. Kyle

Journal:

Year:

2014

Language:

english

File:

PDF, 584 KB

english, 2014