Volume 9; Issue 3

Main
ChemMedChem
Volume 9; Issue 3

ChemMedChem

Volume 9; Issue 3

1

A Chimeric SERM-Histone Deacetylase Inhibitor Approach to Breast Cancer Therapy

Patel, Hitisha K., Siklos, Marton I., Abdelkarim, Hazem, Mendonca, Emma L., Vaidya, Aditya, Petukhov, Pavel A., Thatcher, Gregory R. J.

Journal:

Year:

2014

Language:

english

File:

PDF, 828 KB

english, 2014

2

Structured Water Molecules in the Binding Site of Bromodomains Can Be Displaced by Cosolvent

Huang, Danzhi, Rossini, Emanuele, Steiner, Sandra, Caflisch, Amedeo

Journal:

Year:

2014

Language:

english

File:

PDF, 1.56 MB

english, 2014

3

Naphthyridines as Novel BET Family Bromodomain Inhibitors

Mirguet, Olivier, Lamotte, Yann, Chung, Chun-wa, Bamborough, Paul, Delannée, Delphine, Bouillot, Anne, Gellibert, Françoise, Krysa, Gael, Lewis, Antonia, Witherington, Jason, Huet, Pascal, Dudit, Yann

Journal:

Year:

2014

Language:

english

File:

PDF, 996 KB

english, 2014

4

The Effect of Various Zinc Binding Groups on Inhibition of Histone Deacetylases 1-11

Madsen, Andreas S., Kristensen, Helle M. E., Lanz, Gyrithe, Olsen, Christian A.

Journal:

Year:

2014

Language:

english

File:

PDF, 2.20 MB

english, 2014

5

Toward Drug Repurposing in Epigenetics: Olsalazine as a Hypomethylating Compound Active in a Cellular Context

Méndez-Lucio, Oscar, Tran, Jeremy, Medina-Franco, José L., Meurice, Nathalie, Muller, Mark

Journal:

Year:

2014

Language:

english

File:

PDF, 648 KB

english, 2014

6

Rational Design of Substrate-Based Multivalent Inhibitors of the Histone Acetyltransferase Tip60

Yang, Chao, Ngo, Liza, Zheng, Y. George

Journal:

Year:

2014

Language:

english

File:

PDF, 269 KB

english, 2014

7

Design, Synthesis, and Biological Activity of NCC149 Derivatives as Histone Deacetylase 8-Selective Inhibitors

Suzuki, Takayoshi, Muto, Nobusuke, Bando, Masashige, Itoh, Yukihiro, Masaki, Ayako, Ri, Masaki, Ota, Yosuke, Nakagawa, Hidehiko, Iida, Shinsuke, Shirahige, Katsuhiko, Miyata, Naoki

Journal:

Year:

2014

Language:

english

File:

PDF, 749 KB

english, 2014

8

Bromodomains and Their Pharmacological Inhibitors

Gallenkamp, Daniel, Gelato, Kathy A., Haendler, Bernard, Weinmann, Hilmar

Journal:

Year:

2014

Language:

english

File:

PDF, 1.83 MB

english, 2014

9

Epigenetic Molecular Recognition: A Biomolecular Modeling Perspective

Vellore, Nadeem A., Baron, Riccardo

Journal:

Year:

2014

Language:

english

File:

PDF, 2.35 MB

english, 2014

10

A Cell-Permeable Ester Derivative of the JmjC Histone Demethylase Inhibitor IOX1

Schiller, Rachel, Scozzafava, Giuseppe, Tumber, Anthony, Wickens, James R., Bush, Jacob T., Rai, Ganesha, Lejeune, Clarisse, Choi, Hwanho, Yeh, Tzu-Lan, Chan, Mun Chiang, Mott, Bryan T., McCullagh, Ja

Journal:

Year:

2014

Language:

english

File:

PDF, 662 KB

english, 2014

11

Design, Synthesis and Biological Evaluation of 4-Amino- N -(4-aminophenyl)benzamide Analogues of Quinoline-Based SGI-1027 as Inhibitors of DNA Methylation

Rilova, Elodie, Erdmann, Alexandre, Gros, Christina, Masson, Véronique, Aussagues, Yannick, Poughon-Cassabois, Valérie, Rajavelu, Arumugam, Jeltsch, Albert, Menon, Yoann, Novosad, Natacha, Gregoire, J

Journal:

Year:

2014

Language:

english

File:

PDF, 861 KB

english, 2014

12

Lysine Deacetylase (KDAC) Regulatory Pathways: an Alternative Approach to Selective Modulation

Van Dyke, Michael W.

Journal:

Year:

2014

Language:

english

File:

PDF, 1.03 MB

english, 2014

13

Towards Selective Inhibition of Histone Deacetylase Isoforms: What Has Been Achieved, Where We Are and What Will Be Next

Thaler, Florian, Mercurio, Ciro

Journal:

Year:

2014

Language:

english

File:

PDF, 669 KB

english, 2014

14

Histone Deacetylase Inhibitors with Enhanced Enzymatic Inhibition Effects and Potent in vitro and in vivo Antitumor Activities

Zhang, Lei, Zhang, Yingjie, Chou, C. James, Inks, Elizabeth S., Wang, Xuejian, Li, Xiaoguang, Hou, Jinning, Xu, Wenfang

Journal:

Year:

2014

Language:

english

File:

PDF, 1.11 MB

english, 2014

15

The Role of Long Noncoding RNAs in the Epigenetic Control of Gene Expression

Morlando, Mariangela, Ballarino, Monica, Fatica, Alessandro, Bozzoni, Irene

Journal:

Year:

2014

Language:

english

File:

PDF, 501 KB

english, 2014

16

Mind the Methyl: Methyllysine Binding Proteins in Epigenetic Regulation

Wagner, Tobias, Robaa, Dina, Sippl, Wolfgang, Jung, Manfred

Journal:

Year:

2014

Language:

english

File:

PDF, 4.80 MB

english, 2014

17

Discovery of Potent HDAC Inhibitors Based on Chlamydocin with Inhibitory Effects on Cell Migration

Wang, Shimiao, Li, Xiaohui, Wei, Yingdong, Xiu, Zhilong, Nishino, Norikazu

Journal:

Year:

2014

Language:

english

File:

PDF, 1.17 MB

english, 2014

18

Cover Picture: A Chimeric SERM-Histone Deacetylase Inhibitor Approach to Breast Cancer Therapy (ChemMedChem 3/2014)

Patel, Hitisha K., Siklos, Marton I., Abdelkarim, Hazem, Mendonca, Emma L., Vaidya, Aditya, Petukhov, Pavel A., Thatcher, Gregory R. J.

Journal:

Year:

2014

Language:

english

File:

PDF, 705 KB

english, 2014

19

Back Cover: The Effect of Various Zinc Binding Groups on Inhibition of Histone Deacetylases 1-11 (ChemMedChem 3/2014)

Madsen, Andreas S., Kristensen, Helle M. E., Lanz, Gyrithe, Olsen, Christian A.

Journal:

Year:

2014

File:

PDF, 978 KB

2014

20

Targeting Epigenetics in Drug Discovery

Journal:

Year:

2014

Language:

english

File:

PDF, 458 KB

english, 2014

21

An Update on Lysine Deacylases Targeting the Expanding “Acylome”

Olsen, Christian A.

Journal:

Year:

2014

Language:

english

File:

PDF, 318 KB

english, 2014

22

Inside Cover: A Chemical Tool for In Vitro and In Vivo Precipitation of Lysine Methyltransferase G9a (ChemMedChem 3/2014)

Konze, Kyle D., Pattenden, Samantha G., Liu, Feng, Barsyte-Lovejoy, Dalia, Li, Fengling, Simon, Jeremy M., Davis, Ian J., Vedadi, Masoud, Jin, Jian

Journal:

Year:

2014

File:

PDF, 1.35 MB

2014

23

Synthesis, Antimalarial Properties, and SAR Studies of Alkoxyurea-Based HDAC Inhibitors

Hansen, Finn K., Skinner-Adams, Tina S., Duffy, Sandra, Marek, Linda, Sumanadasa, Subathdrage D. M., Kuna, Krystina, Held, Jana, Avery, Vicky M., Andrews, Katherine T., Kurz, Thomas

Journal:

Year:

2014

Language:

english

File:

PDF, 325 KB

english, 2014

24

Graphical Abstract: ChemMedChem 3/2014

Journal:

Year:

2014

Language:

english

File:

PDF, 2.73 MB

english, 2014

25

Quinoline-Based p300 Histone Acetyltransferase Inhibitors with Pro-apoptotic Activity in Human Leukemia U937 Cells

Lenoci, Alessia, Tomassi, Stefano, Conte, Mariarosaria, Benedetti, Rosaria, Rodriguez, Veronica, Carradori, Simone, Secci, Daniela, Castellano, Sabrina, Sbardella, Gianluca, Filetici, Patrizia, Novell

Journal:

Year:

2014

Language:

english

File:

PDF, 474 KB

english, 2014

26

Non-radioactive Protein Lysine Methyltransferase Microplate Assay Based on Reading Domains

Kudithipudi, Srikanth, Kusevic, Denis, Jeltsch, Albert

Journal:

Year:

2014

Language:

english

File:

PDF, 740 KB

english, 2014

27

Lactam-Based HDAC Inhibitors for Anticancer Chemotherapy: Restoration of RUNX3 by Posttranslational Modification and Epigenetic Control

Cho, Misun, Choi, Eunhyun, Kim, Jae Hyun, Kim, Hwan, Kim, Hwan Mook, Lee, Jang Ik, Hwang, Ki-Chul, Kim, Hyun-Jung, Han, Gyoonhee

Journal:

Year:

2014

Language:

english

File:

PDF, 760 KB

english, 2014

28

Synthetic Chromatin Approaches To Probe the Writing and Erasing of Histone Modifications

Journal:

Year:

2014

Language:

english

File:

PDF, 1.04 MB

english, 2014

29

Spotlights on our sister journals: ChemMedChem 3/2014

Journal:

Year:

2014

Language:

english

File:

PDF, 1.54 MB

english, 2014

30

A Chemical Tool for In Vitro and In Vivo Precipitation of Lysine Methyltransferase G9a

Konze, Kyle D., Pattenden, Samantha G., Liu, Feng, Barsyte-Lovejoy, Dalia, Li, Fengling, Simon, Jeremy M., Davis, Ian J., Vedadi, Masoud, Jin, Jian

Journal:

Year:

2014

Language:

english

File:

PDF, 645 KB

english, 2014

To build up a library is to create a life. It’s never just a random collection of books.

— Carlos María Domínguez

Official channel

Z-Library Desktop Launcher

Tor version

Z-Library

Z-Library Since 2009 support@z-lib.do

EnglishРусскийEspañolItalianoελληνικάاللغة العربيةBahasa IndonesiaBahasa Malaysiaहिन्दीDeutschFrançaisPortuguêsУкраїнськаPolski中文繁體中文日本語Tiếng ViệtAzərbaycan DiliՀայոց լեզուภาษาไทยTürk Diliქართველიবাংলাپښتوతెలుగుاردو한국어SrpskiБългарски