Volume 13; Issue 7

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Clinical Cancer Research
Volume 13; Issue 7

Clinical Cancer Research

Volume 13; Issue 7

1

c-Met Is a Potentially New Therapeutic Target for Treatment of Human Melanoma

Puri, N., Ahmed, S., Janamanchi, V., Tretiakova, M., Zumba, O., Krausz, T., Jagadeeswaran, R., Salgia, R.

Journal:

Clinical Cancer Research

Year:

2007

Language:

english

File:

PDF, 561 KB

english, 2007

2

The Therapeutic and Preventive Effect of RRR- -Vitamin E Succinate on Prostate Cancer via Induction of Insulin-Like Growth Factor Binding Protein-3

Yin, Y., Ni, J., Chen, M., DiMaggio, M. A., Guo, Y., Yeh, S.

Journal:

Clinical Cancer Research

Year:

2007

Language:

english

File:

PDF, 767 KB

english, 2007

3

Loss of the Mismatch Repair Protein MSH6 in Human Glioblastomas Is Associated with Tumor Progression during Temozolomide Treatment

Cahill, D. P., Levine, K. K., Betensky, R. A., Codd, P. J., Romany, C. A., Reavie, L. B., Batchelor, T. T., Futreal, P. A., Stratton, M. R., Curry, W. T., Iafrate, A. J., Louis, D. N.

Journal:

Clinical Cancer Research

Year:

2007

Language:

english

File:

PDF, 309 KB

english, 2007

4

A Phase I Pharmacokinetic and Pharmacodynamic Study of S-3304, a Novel Matrix Metalloproteinase Inhibitor, in Patients with Advanced and Refractory Solid Tumors

Chiappori, A. A., Eckhardt, S. G., Bukowski, R., Sullivan, D. M., Ikeda, M., Yano, Y., Yamada-Sawada, T., Kambayashi, Y., Tanaka, K., Javle, M. M., Mekhail, T., O'Bryant, C. L., Creaven, P. J.

Journal:

Clinical Cancer Research

Year:

2007

Language:

english

File:

PDF, 408 KB

english, 2007

5

A Phase I Pharmacokinetic and Pharmacodynamic Study of PX-12, a Novel Inhibitor of Thioredoxin-1, in Patients with Advanced Solid Tumors

Ramanathan, R. K., Kirkpatrick, D. L., Belani, C. P., Friedland, D., Green, S. B., Chow, H-H. S., Cordova, C. A., Stratton, S. P., Sharlow, E. R., Baker, A., Dragovich, T.

Journal:

Clinical Cancer Research

Year:

2007

Language:

english

File:

PDF, 302 KB

english, 2007

6

Fluctuating and Diffusion-Limited Hypoxia in Hypoxia-Induced Metastasis

Rofstad, E. K., Galappathi, K., Mathiesen, B., Ruud, E.-B. M.

Journal:

Clinical Cancer Research

Year:

2007

Language:

english

File:

PDF, 438 KB

english, 2007

7

Potent siRNA Inhibitors of Ribonucleotide Reductase Subunit RRM2 Reduce Cell Proliferation In vitro and In vivo

Heidel, J. D., Liu, J. Y.-C., Yen, Y., Zhou, B., Heale, B. S.E., Rossi, J. J., Bartlett, D. W., Davis, M. E.

Journal:

Clinical Cancer Research

Year:

2007

Language:

english

File:

PDF, 596 KB

english, 2007

8

Mcl-1 Is a Relevant Therapeutic Target in Acute and Chronic Lymphoid Malignancies: Down-Regulation Enhances Rituximab-Mediated Apoptosis and Complement-Dependent Cytotoxicity

Hussain, S.-R. A., Cheney, C. M., Johnson, A. J., Lin, T. S., Grever, M. R., Caligiuri, M. A., Lucas, D. M., Byrd, J. C.

Journal:

Clinical Cancer Research

Year:

2007

Language:

english

File:

PDF, 591 KB

english, 2007

9

Molecular Characterization of Waldenstrom's Macroglobulinemia Reveals Frequent Occurrence of Two B-Cell Clones Having Distinct IgH VDJ Sequences

Kriangkum, J., Taylor, B. J., Treon, S. P., Mant, M. J., Reiman, T., Belch, A. R., Pilarski, L. M.

Journal:

Clinical Cancer Research

Year:

2007

Language:

english

File:

PDF, 527 KB

english, 2007

10

Population-Based Molecular Prognosis of Breast Cancer by Transcriptional Profiling

Ma, Y., Qian, Y., Wei, L., Abraham, J., Shi, X., Castranova, V., Harner, E. J., Flynn, D. C., Guo, L.

Journal:

Clinical Cancer Research

Year:

2007

Language:

english

File:

PDF, 378 KB

english, 2007

11

Transfection with Anti-p65 Intrabody Suppresses Invasion and Angiogenesis in Glioma Cells by Blocking Nuclear Factor- B Transcriptional Activity

Li, L., Gondi, C. S., Dinh, D. H., Olivero, W. C., Gujrati, M., Rao, J. S.

Journal:

Clinical Cancer Research

Year:

2007

Language:

english

File:

PDF, 1.07 MB

english, 2007

12

Utility of Circulating B-RAF DNA Mutation in Serum for Monitoring Melanoma Patients Receiving Biochemotherapy

Shinozaki, M., O'Day, S. J., Kitago, M., Amersi, F., Kuo, C., Kim, J., Wang, H.-J., Hoon, D. S.B.

Journal:

Clinical Cancer Research

Year:

2007

Language:

english

File:

PDF, 290 KB

english, 2007

13

The Potential of Antiangiogenic Therapy in Non-Small Cell Lung Cancer

Journal:

Clinical Cancer Research

Year:

2007

Language:

english

File:

PDF, 357 KB

english, 2007

14

Morin (3,5,7,2',4'-Pentahydroxyflavone) Abolishes Nuclear Factor- B Activation Induced by Various Carcinogens and Inflammatory Stimuli, Leading to Suppression of Nuclear Factor- B-Regulated Gene Expression and Up-regulation of Apoptosis

Manna, S. K., Aggarwal, R. S., Sethi, G., Aggarwal, B. B., Ramesh, G. T.

Journal:

Clinical Cancer Research

Year:

2007

Language:

english

File:

PDF, 424 KB

english, 2007

15

Chemosensitization of Cancer In vitro and In vivo by Nitric Oxide Signaling

Frederiksen, L. J., Sullivan, R., Maxwell, L. R., Macdonald-Goodfellow, S. K., Adams, M. A., Bennett, B. M., Siemens, D. R., Graham, C. H.

Journal:

Clinical Cancer Research

Year:

2007

Language:

english

File:

PDF, 454 KB

english, 2007

16

Microtubule-Associated Protein-tau is a Bifunctional Predictor of Endocrine Sensitivity and Chemotherapy Resistance in Estrogen Receptor-Positive Breast Cancer

Andre, F., Hatzis, C., Anderson, K., Sotiriou, C., Mazouni, C., Mejia, J., Wang, B., Hortobagyi, G. N., Symmans, W. F., Pusztai, L.

Journal:

Clinical Cancer Research

Year:

2007

Language:

english

File:

PDF, 486 KB

english, 2007

17

Menatetrenone, a Vitamin K2 Analogue, Inhibits Hepatocellular Carcinoma Cell Growth by Suppressing Cyclin D1 Expression through Inhibition of Nuclear Factor B Activation

Ozaki, I., Zhang, H., Mizuta, T., Ide, Y., Eguchi, Y., Yasutake, T., Sakamaki, T., Pestell, R. G., Yamamoto, K.

Journal:

Clinical Cancer Research

Year:

2007

Language:

english

File:

PDF, 848 KB

english, 2007

18

Stromal Myofibroblasts Predict Disease Recurrence for Colorectal Cancer

Tsujino, T., Seshimo, I., Yamamoto, H., Ngan, C. Y., Ezumi, K., Takemasa, I., Ikeda, M., Sekimoto, M., Matsuura, N., Monden, M.

Journal:

Clinical Cancer Research

Year:

2007

Language:

english

File:

PDF, 846 KB

english, 2007

19

Unraveling the Mechanisms of Endocrine Resistance in Breast Cancer: New Therapeutic Opportunities

Massarweh, S., Schiff, R.

Journal:

Clinical Cancer Research

Year:

2007

Language:

english

File:

PDF, 252 KB

english, 2007

20

Identification of a Highly Effective Rapamycin Schedule that Markedly Reduces the Size, Multiplicity, and Phenotypic Progression of Tobacco Carcinogen-Induced Murine Lung Tumors

Granville, C. A., Warfel, N., Tsurutani, J., Hollander, M. C., Robertson, M., Fox, S. D., Veenstra, T. D., Issaq, H. J., Linnoila, R. I., Dennis, P. A.

Journal:

Clinical Cancer Research

Year:

2007

Language:

english

File:

PDF, 603 KB

english, 2007

21

Selective Killing of Cancer Cells by Leaf Extract of Ashwagandha: Identification of a Tumor-Inhibitory Factor and the First Molecular Insights to Its Effect

Widodo, N., Kaur, K., Shrestha, B. G., Takagi, Y., Ishii, T., Wadhwa, R., Kaul, S. C.

Journal:

Clinical Cancer Research

Year:

2007

Language:

english

File:

PDF, 598 KB

english, 2007

22

Targeting Checkpoint Kinase 1 in Cancer Therapeutics

Tse, A. N., Carvajal, R., Schwartz, G. K.

Journal:

Clinical Cancer Research

Year:

2007

Language:

english

File:

PDF, 312 KB

english, 2007

23

Selective Tumor Targeting by the Hypoxia-Activated Prodrug AQ4N Blocks Tumor Growth and Metastasis in Preclinical Models of Pancreatic Cancer

Lalani, A. S., Alters, S. E., Wong, A., Albertella, M. R., Cleland, J. L., Henner, W. D.

Journal:

Clinical Cancer Research

Year:

2007

Language:

english

File:

PDF, 863 KB

english, 2007

24

Effects of the Administration of High-Dose Interleukin-2 on Immunoregulatory Cell Subsets in Patients with Advanced Melanoma and Renal Cell Cancer

van derVliet, H. J.J., Koon, H. B., Yue, S. C., Uzunparmak, B., Seery, V., Gavin, M. A., Rudensky, A. Y., Atkins, M. B., Balk, S. P., Exley, M. A.

Journal:

Clinical Cancer Research

Year:

2007

Language:

english

File:

PDF, 493 KB

english, 2007

25

Accelerated Preclinical Testing Using Transplanted Tumors from Genetically Engineered Mouse Breast Cancer Models

Varticovski, L., Hollingshead, M. G., Robles, A. I., Wu, X., Cherry, J., Munroe, D. J., Lukes, L., Anver, M. R., Carter, J. P., Borgel, S. D., Stotler, H., Bonomi, C. A., Nunez, N. P., Hursting, S. D.

Journal:

Clinical Cancer Research

Year:

2007

Language:

english

File:

PDF, 610 KB

english, 2007

26

3q26 Amplification and Polysomy of Chromosome 3 in Squamous Cell Lesions of the Lung: A Fluorescence In situ Hybridization Study

Pelosi, G., Del Curto, B., Trubia, M., Nicholson, A. G., Manzotti, M., Veronesi, G., Spaggiari, L., Maisonneuve, P., Pasini, F., Terzi, A., Iannucci, A., Viale, G.

Journal:

Clinical Cancer Research

Year:

2007

Language:

english

File:

PDF, 508 KB

english, 2007

27

Circulating Tumor Cell Analysis in Patients with Progressive Castration-Resistant Prostate Cancer

Shaffer, D. R., Leversha, M. A., Danila, D. C., Lin, O., Gonzalez-Espinoza, R., Gu, B., Anand, A., Smith, K., Maslak, P., Doyle, G. V., Terstappen, L. W.M.M., Lilja, H., Heller, G., Fleisher, M., Sche

Journal:

Clinical Cancer Research

Year:

2007

Language:

english

File:

PDF, 487 KB

english, 2007

28

-2-Microglobulin Is an Androgen-Regulated Secreted Protein Elevated in Serum of Patients with Advanced Prostate Cancer

Gross, M., Top, I., Laux, I., Katz, J., Curran, J., Tindell, C., Agus, D.

Journal:

Clinical Cancer Research

Year:

2007

Language:

english

File:

PDF, 616 KB

english, 2007

29

Phase I Evaluation of a Fully Human Anti- v Integrin Monoclonal Antibody (CNTO 95) in Patients with Advanced Solid Tumors

Mullamitha, S. A., Ton, N. C., Parker, G. J.M., Jackson, A., Julyan, P. J., Roberts, C., Buonaccorsi, G. A., Watson, Y., Davies, K., Cheung, S., Hope, L., Valle, J. W., Radford, J. A., Lawrance, J., S

Journal:

Clinical Cancer Research

Year:

2007

Language:

english

File:

PDF, 504 KB

english, 2007

30

5-Aza-2'-Deoxycytidine Delays Androgen-Independent Disease and Improves Survival in the Transgenic Adenocarcinoma of the Mouse Prostate Mouse Model of Prostate Cancer

Zorn, C. S., Wojno, K. J., McCabe, M. T., Kuefer, R., Gschwend, J. E., Day, M. L.

Journal:

Clinical Cancer Research

Year:

2007

Language:

english

File:

PDF, 541 KB

english, 2007

31

Synergism between Arsenic Trioxide and Heat Shock Protein 90 Inhibitors on Signal Transducer and Activator of Transcription Protein 3 Activity--Pharmacodynamic Drug-Drug Interaction Modeling

Wetzler, M., Earp, J. C., Brady, M. T., Keng, M. K., Jusko, W. J.

Journal:

Clinical Cancer Research

Year:

2007

Language:

english

File:

PDF, 694 KB

english, 2007

32

Preclinical Studies of TW-37, a New Nonpeptidic Small-Molecule Inhibitor of Bcl-2, in Diffuse Large Cell Lymphoma Xenograft Model Reveal Drug Action on Both Bcl-2 and Mcl-1

Mohammad, R. M., Goustin, A. S., Aboukameel, A., Chen, B., Banerjee, S., Wang, G., Nikolovska-Coleska, Z., Wang, S., Al-Katib, A.

Journal:

Clinical Cancer Research

Year:

2007

Language:

english

File:

PDF, 748 KB

english, 2007

33

Estrogen Receptor Expression Is Associated with Tamoxifen Response in ER -Negative Breast Carcinoma

Gruvberger-Saal, S. K., Bendahl, P.-O., Saal, L. H., Laakso, M., Hegardt, C., Eden, P., Peterson, C., Malmstrom, P., Isola, J., Borg, A., Ferno, M.

Journal:

Clinical Cancer Research

Year:

2007

Language:

english

File:

PDF, 528 KB

english, 2007

34

The Therapeutic Potential of Hepatocyte Growth Factor to Sensitize Ovarian Cancer Cells to Cisplatin and Paclitaxel In vivo

Bardella, C., Dettori, D., Olivero, M., Coltella, N., Mazzone, M., Di Renzo, M. F.

Journal:

Clinical Cancer Research

Year:

2007

Language:

english

File:

PDF, 349 KB

english, 2007

35

Systemic CTLA-4 Blockade Ameliorates Glioma-Induced Changes to the CD4+ T Cell Compartment without Affecting Regulatory T-Cell Function

Fecci, P. E., Ochiai, H., Mitchell, D. A., Grossi, P. M., Sweeney, A. E., Archer, G. E., Cummings, T., Allison, J. P., Bigner, D. D., Sampson, J. H.

Journal:

Clinical Cancer Research

Year:

2007

Language:

english

File:

PDF, 975 KB

english, 2007

36

Evaluation of Plasma Insulin-like Growth Factor Binding Protein 2 and Her-2 Extracellular Domain as Biomarkers for 17-Allylamino-17-Demethoxygeldanamycin Treatment of Adult Patients with Advanced Solid Tumors

Eiseman, J. L., Guo, J., Ramanathan, R. K., Belani, C. P., Solit, D. B., Scher, H. I., Ivy, S. P., Zuhowski, E. G., Egorin, M. J.

Journal:

Clinical Cancer Research

Year:

2007

Language:

english

File:

PDF, 202 KB

english, 2007

37

Plasma Matrix Metalloproteinase-9 Level Is Better than Serum Matrix Metalloproteinase-9 Level to Predict Gastric Cancer Evolution

Wu, C.-Y., Wu, M.-S., Chiang, E.-P., Chen, Y.-J., Chen, C.-J., Chi, N.-H., Shih, Y.-T., Chen, G.-H., Lin, J.-T.

Journal:

Clinical Cancer Research

Year:

2007

Language:

english

File:

PDF, 344 KB

english, 2007

38

Adrenal Androgen Levels as Predictors of Outcome in Prostate Cancer Patients Treated with Ketoconazole Plus Antiandrogen Withdrawal: Results from a Cancer and Leukemia Group B Study

Ryan, C. J., Halabi, S., Ou, S.-S., Vogelzang, N. J., Kantoff, P., Small, E. J.

Journal:

Clinical Cancer Research

Year:

2007

Language:

english

File:

PDF, 262 KB

english, 2007

39

Promoter Hypermethylation Identifies Progression Risk in Bladder Cancer

Yates, D. R., Rehman, I., Abbod, M. F., Meuth, M., Cross, S. S., Linkens, D. A., Hamdy, F. C., Catto, J. W.F.

Journal:

Clinical Cancer Research

Year:

2007

Language:

english

File:

PDF, 760 KB

english, 2007

40

Angiopoietin 2 Is a Potential Mediator of High-Dose Interleukin 2-Induced Vascular Leak

Gallagher, D. C., Bhatt, R. S., Parikh, S. M., Patel, P., Seery, V., McDermott, D. F., Atkins, M. B., Sukhatme, V. P.

Journal:

Clinical Cancer Research

Year:

2007

Language:

english

File:

PDF, 459 KB

english, 2007

41

Clinical Significance and Therapeutic Potential of the Programmed Death-1 Ligand/Programmed Death-1 Pathway in Human Pancreatic Cancer

Nomi, T., Sho, M., Akahori, T., Hamada, K., Kubo, A., Kanehiro, H., Nakamura, S., Enomoto, K., Yagita, H., Azuma, M., Nakajima, Y.

Journal:

Clinical Cancer Research

Year:

2007

Language:

english

File:

PDF, 477 KB

english, 2007

42

Tumor-Infiltrating Foxp3-CD4+CD25+ T Cells Predict Poor Survival in Renal Cell Carcinoma

Siddiqui, S. A., Frigola, X., Bonne-Annee, S., Mercader, M., Kuntz, S. M., Krambeck, A. E., Sengupta, S., Dong, H., Cheville, J. C., Lohse, C. M., Krco, C. J., Webster, W. S., Leibovich, B. C., Blute,

Journal:

Clinical Cancer Research

Year:

2007

Language:

english

File:

PDF, 436 KB

english, 2007

43

Hypoxia and Metastasis

Chaudary, N., Hill, R. P.

Journal:

Clinical Cancer Research

Year:

2007

Language:

english

File:

PDF, 217 KB

english, 2007

44

Identification of Molecular Predictors of Response in a Study of Tipifarnib Treatment in Relapsed and Refractory Acute Myelogenous Leukemia

Raponi, M., Harousseau, J.-L., Lancet, J. E., Lowenberg, B., Stone, R., Zhang, Y., Rackoff, W., Wang, Y., Atkins, D.

Journal:

Clinical Cancer Research

Year:

2007

Language:

english

File:

PDF, 385 KB

english, 2007