Volume 14; Issue 12

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Clinical Cancer Research
Volume 14; Issue 12

Clinical Cancer Research

Volume 14; Issue 12

1

Is There a Role for Circulating Tumor Cells in the Management of Breast Cancer?

Hayes, D. F., Smerage, J.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 309 KB

english, 2008

2

Selective Inhibition of BRCA2-Deficient Mammary Tumor Cell Growth by AZD2281 and Cisplatin

Evers, B., Drost, R., Schut, E., de Bruin, M., van der Burg, E., Derksen, P. W.B., Holstege, H., Liu, X., van Drunen, E., Beverloo, H. B., Smith, G. C.M., Martin, N. M.B., Lau, A., O'Connor, M. J., Jo

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 1.20 MB

english, 2008

3

Improved Prediction of Disease Relapse after Radical Prostatectomy through a Panel of Preoperative Blood-Based Biomarkers

Shariat, S. F., Karam, J. A., Walz, J., Roehrborn, C. G., Montorsi, F., Margulis, V., Saad, F., Slawin, K. M., Karakiewicz, P. I.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 189 KB

english, 2008

4

Phase I Study of GTI-2040, an Antisense to Ribonucleotide Reductase, in Combination with High-Dose Cytarabine in Patients with Acute Myeloid Leukemia

Klisovic, R. B., Blum, W., Wei, X., Liu, S., Liu, Z., Xie, Z., Vukosavljevic, T., Kefauver, C., Huynh, L., Pang, J., Zwiebel, J. A., Devine, S., Byrd, J. C., Grever, M. R., Chan, K., Marcucci, G.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 247 KB

english, 2008

5

A Metastasis Modifier Locus on Human Chromosome 8p in Uveal Melanoma Identified by Integrative Genomic Analysis

Onken, M. D., Worley, L. A., Harbour, J. W.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 744 KB

english, 2008

6

Intraoperative 186Re-Liposome Radionuclide Therapy in a Head and Neck Squamous Cell Carcinoma Xenograft Positive Surgical Margin Model

Wang, S. X., Bao, A., Herrera, S. J., Phillips, W. T., Goins, B., Santoyo, C., Miller, F. R., Otto, R. A.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 342 KB

english, 2008

7

Tumor Vascular Maturation and Improved Drug Delivery Induced by Methylselenocysteine Leads to Therapeutic Synergy with Anticancer Drugs

Bhattacharya, A., Seshadri, M., Oven, S. D., Toth, K., Vaughan, M. M., Rustum, Y. M.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 403 KB

english, 2008

8

Are There Any Ethnic Differences in Molecular Predictors of Erlotinib Efficacy in Advanced Non-Small Cell Lung Cancer?

Ahn, M.-J., Park, B.-B., Ahn, J. S., Kim, S. W., Kim, H.-T., Lee, J. S., Kang, J. H., Cho, J. Y., Song, H. S., Park, S. H., Sohn, C. H., Shin, S. W., Choi, J. H., Ki, C.-S., Park, C. K., Holmes, A. J.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 184 KB

english, 2008

9

RHAMM, p21 Combined Phenotype Identifies Microsatellite Instability-High Colorectal Cancers with a Highly Adverse Prognosis

Zlobec, I., Baker, K., Terracciano, L. M., Lugli, A.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 427 KB

english, 2008

10

Phase II Study of Dasatinib in Philadelphia Chromosome-Negative Acute and Chronic Myeloid Diseases, Including Systemic Mastocytosis

Verstovsek, S., Tefferi, A., Cortes, J., O'Brien, S., Garcia-Manero, G., Pardanani, A., Akin, C., Faderl, S., Manshouri, T., Thomas, D., Kantarjian, H.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 219 KB

english, 2008

11

BRCA1 and BRCA2 Mutation Prevalence and Clinical Characteristics of a Population-Based Series of Ovarian Cancer Cases from Denmark

Soegaard, M., Kjaer, S. K., Cox, M., Wozniak, E., Hogdall, E., Hogdall, C., Blaakaer, J., Jacobs, I. J., Gayther, S. A., Ramus, S. J.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 195 KB

english, 2008

12

Advances in the Development of Cancer Therapeutics Directed against the RAS-Mitogen-Activated Protein Kinase Pathway

Sebolt-Leopold, J. S.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 295 KB

english, 2008

13

Transforming Growth Factor- Receptor Blockade Augments the Effectiveness of Adoptive T-Cell Therapy of Established Solid Cancers

Wallace, A., Kapoor, V., Sun, J., Mrass, P., Weninger, W., Heitjan, D. F., June, C., Kaiser, L. R., Ling, L. E., Albelda, S. M.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 326 KB

english, 2008

14

The Development of Phase I Cancer Trial Methodologies: the Use of Pharmacokinetic and Pharmacodynamic End Points Sets the Scene for Phase 0 Cancer Clinical Trials

Calvert, A. H., Plummer, R.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 292 KB

english, 2008

15

A Phase II Pharmacodynamic Study of Erlotinib in Patients with Advanced Non-Small Cell Lung Cancer Previously Treated with Platinum-Based Chemotherapy

Felip, E., Rojo, F., Reck, M., Heller, A., Klughammer, B., Sala, G., Cedres, S., Peralta, S., Maacke, H., Foernzler, D., Parera, M., Mocks, J., Saura, C., Gatzemeier, U., Baselga, J.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 213 KB

english, 2008

16

Increase in Brain Tumor Permeability in Glioma-Bearing Rats with Nitric Oxide Donors

Yin, D., Wang, X., Konda, B. M., Ong, J. M., Hu, J., Sacapano, M. R., Ko, M. K., Espinoza, A. J., Irvin, D. K., Shu, Y., Black, K. L.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 498 KB

english, 2008

17

From the editor

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 81 KB

english, 2008

18

Association of p16 Homozygous Deletions with Clinicopathologic Characteristics and EGFR/KRAS/p53 Mutations in Lung Adenocarcinoma

Iwakawa, R., Kohno, T., Anami, Y., Noguchi, M., Suzuki, K., Matsuno, Y., Mishima, K., Nishikawa, R., Tashiro, F., Yokota, J.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 455 KB

english, 2008

19

MDM2 Promoter Polymorphism and Pancreatic Cancer Risk and Prognosis

Asomaning, K., Reid, A. E., Zhou, W., Heist, R. S., Zhai, R., Su, L., Kwak, E. L., Blaszkowsky, L., Zhu, A. X., Ryan, D. P., Christiani, D. C., Liu, G.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 176 KB

english, 2008

20

DNA-Dependent Protein Kinase Is a Therapeutic Target and an Indicator of Poor Prognosis in B-Cell Chronic Lymphocytic Leukemia

Willmore, E., Elliott, S. L., Mainou-Fowler, T., Summerfield, G. P., Jackson, G. H., O'Neill, F., Lowe, C., Carter, A., Harris, R., Pettitt, A. R., Cano-Soumillac, C., Griffin, R. J., Cowell, I. G., A

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 381 KB

english, 2008

21

The Ethics of Phase 0 Oncology Trials

Abdoler, E., Taylor, H., Wendler, D.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 102 KB

english, 2008

22

Local Recurrence in Mismatch Repair-Proficient Colon Cancer Predicted by an Infiltrative Tumor Border and Lack of CD8+ Tumor-Infiltrating Lymphocytes

Zlobec, I., Terracciano, L. M., Lugli, A.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 182 KB

english, 2008

23

Patient Perspectives on Phase 0 Clinical Trials

Gutierrez, M., Collyar, D.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 124 KB

english, 2008

24

RCAS/SCL-TVA Animal Model Allows Targeted Delivery of Polyoma Middle T Oncogene to Vascular Endothelial Progenitors In vivo and Results in Hemangioma Development

Sausville, J., Molinolo, A. A., Cheng, X., Frampton, J., Takebe, N., Gutkind, J. S., Feldman, R. A.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 622 KB

english, 2008

25

PTEN Loss Does Not Predict for Response to RAD001 (Everolimus) in a Glioblastoma Orthotopic Xenograft Test Panel

Yang, L., Clarke, M. J., Carlson, B. L., Mladek, A. C., Schroeder, M. A., Decker, P., Wu, W., Kitange, G. J., Grogan, P. T., Goble, J. M., Uhm, J., Galanis, E., Giannini, C., Lane, H. A., James, C. D.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 402 KB

english, 2008

26

Correction: Letters on Computed Tomography Screening for Lung Cancer

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 28 KB

english, 2008

27

Phase 0 Trials: An Industry Perspective

Eliopoulos, H., Giranda, V., Carr, R., Tiehen, R., Leahy, T., Gordon, G.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 263 KB

english, 2008

28

Heterogeneity of Drug Target Expression Among Metastatic Lesions: Lessons from a Breast Cancer Autopsy Program

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 261 KB

english, 2008

29

Effect of Interleukin-10 Gene Polymorphisms on Clinical Outcome of Patients with Aggressive Non-Hodgkin's Lymphoma: An Exploratory Study

Kube, D., Hua, T.-D., von Bonin, F., Schoof, N., Zeynalova, S., Kloss, M., Gocht, D., Potthoff, B., Tzvetkov, M., Brockmoller, J., Loffler, M., Pfreundschuh, M., Trumper, L.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 325 KB

english, 2008

30

Leveraging Exploratory Investigational New Drug Studies to Accelerate Drug Development

Jacobson-Kram, D., Mills, G.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 325 KB

english, 2008

31

Down-Regulation of Hedgehog-Interacting Protein through Genetic and Epigenetic Alterations in Human Hepatocellular Carcinoma

Tada, M., Kanai, F., Tanaka, Y., Tateishi, K., Ohta, M., Asaoka, Y., Seto, M., Muroyama, R., Fukai, K., Imazeki, F., Kawabe, T., Yokosuka, O., Omata, M.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 362 KB

english, 2008

32

Intratumoral Coadministration of Hyaluronidase Enzyme and Oncolytic Adenoviruses Enhances Virus Potency in Metastatic Tumor Models

Ganesh, S., Gonzalez-Edick, M., Gibbons, D., Van Roey, M., Jooss, K.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 702 KB

english, 2008

33

Concerted Potent Humoral Immune Responses to Autoantigens Are Associated with Tumor Destruction and Favorable Clinical Outcomes without Autoimmunity

Sittler, T., Zhou, J., Park, J., Yuen, N. K., Sarantopoulos, S., Mollick, J., Salgia, R., Giobbie-Hurder, A., Dranoff, G., Hodi, F. S.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 241 KB

english, 2008

34

T Regulatory Type 1 Cells in Squamous Cell Carcinoma of the Head and Neck: Mechanisms of Suppression and Expansion in Advanced Disease

Bergmann, C., Strauss, L., Wang, Y., Szczepanski, M. J., Lang, S., Johnson, J. T., Whiteside, T. L.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 598 KB

english, 2008

35

Soluble ErbB3 Levels in Bone Marrow and Plasma of Men with Prostate Cancer

Lin, S.-H., Lee, Y.-C., Choueiri, M. B., Wen, S., Mathew, P., Ye, X., Do, K.-A., Navone, N. M., Kim, J., Tu, S.-M., Yu-Lee, L.-Y., Logothetis, C. J.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 280 KB

english, 2008

36

CIP2A Is Overexpressed in Gastric Cancer and Its Depletion Leads to Impaired Clonogenicity, Senescence, or Differentiation of Tumor Cells

Li, W., Ge, Z., Liu, C., Liu, Z., Bjorkholm, M., Jia, J., Xu, D.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 377 KB

english, 2008

37

Oncologic Phase 0 Trials Incorporating Clinical Pharmacodynamics: from Concept to Patient

Doroshow, J. H., Parchment, R. E.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 249 KB

english, 2008

38

Phosphodiesterase 11A (PDE11A) and Genetic Predisposition to Adrenocortical Tumors

Libe, R., Fratticci, A., Coste, J., Tissier, F., Horvath, A., Ragazzon, B., Rene-Corail, F., Groussin, L., Bertagna, X., Raffin-Sanson, M. L., Stratakis, C. A., Bertherat, J.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 530 KB

english, 2008

39

Suppression of proHB-EGF Carboxy-Terminal Fragment Nuclear Translocation: A New Molecular Target Therapy for Gastric Cancer

Shimura, T., Kataoka, H., Ogasawara, N., Kubota, E., Sasaki, M., Tanida, S., Joh, T.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 930 KB

english, 2008

40

Cytokeratin 10 and Cytokeratin 19: Predictive Markers for Poor Prognosis in Hepatocellular Carcinoma Patients after Curative Resection

Yang, X.-R., Xu, Y., Shi, G.-M., Fan, J., Zhou, J., Ji, Y., Sun, H.-C., Qiu, S.-J., Yu, B., Gao, Q., He, Y.-Z., Qin, W.-Z., Chen, R.-X., Yang, G.-H., Wu, B., Lu, Q., Wu, Z.-Q., Tang, Z.-Y.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 1.05 MB

english, 2008

41

Designing Phase 0 Cancer Clinical Trials

Murgo, A. J., Kummar, S., Rubinstein, L., Gutierrez, M., Collins, J., Kinders, R., Parchment, R. E., Ji, J., Steinberg, S. M., Yang, S. X., Hollingshead, M., Chen, A., Helman, L., Wiltrout, R., Tomasz

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 758 KB

english, 2008

42

Association of Megalin Genetic Polymorphisms with Prostate Cancer Risk and Prognosis

Holt, S. K., Karyadi, D. M., Kwon, E. M., Stanford, J. L., Nelson, P. S., Ostrander, E. A.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 192 KB

english, 2008

43

Oncogenic and Angiogenic Growth Factors Accumulate during Routine Storage of Apheresis Platelet Concentrates

Kanter, J., Khan, S. Y., Kelher, M., Gore, L., Silliman, C. C.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 228 KB

english, 2008

44

Somatic Mutations of JAK1 and JAK3 in Acute Leukemias and Solid Cancers

Jeong, E. G., Kim, M. S., Nam, H. K., Min, C. K., Lee, S., Chung, Y. J., Yoo, N. J., Lee, S. H.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 428 KB

english, 2008

45

Imaging Immune Response In vivo: Cytolytic Action of Genetically Altered T Cells Directed to Glioblastoma Multiforme

Lazovic, J., Jensen, M. C., Ferkassian, E., Aguilar, B., Raubitschek, A., Jacobs, R. E.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 511 KB

english, 2008

46

Affibody Molecules for In vivo Characterization of HER2-Positive Tumors by Near-Infrared Imaging

Lee, S. B., Hassan, M., Fisher, R., Chertov, O., Chernomordik, V., Kramer-Marek, G., Gandjbakhche, A., Capala, J.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 746 KB

english, 2008

47

Tissue-Based Research in Kidney Cancer: Current Challenges and Future Directions

Signoretti, S., Bratslavsky, G., Waldman, F. M., Reuter, V. E., Haaga, J., Merino, M., Thomas, G. V., Pins, M. R., Libermann, T., Gillespie, J., Tomaszewski, J. E., Compton, C. C., Hruszkewycz, A., Li

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 205 KB

english, 2008

48

ssDNA-Binding Protein 2 Is Frequently Hypermethylated and Suppresses Cell Growth in Human Prostate Cancer

Liu, J.-W., Nagpal, J. K., Sun, W., Lee, J., Kim, M. S., Ostrow, K. L., Zhou, S., Jeronimo, C., Henrique, R., Van Criekinge, W., Moon, C. S., Califano, J. A., Trink, B., Sidransky, D.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 390 KB

english, 2008

49

Dasatinib Cellular Uptake and Efflux in Chronic Myeloid Leukemia Cells: Therapeutic Implications

Hiwase, D. K., Saunders, V., Hewett, D., Frede, A., Zrim, S., Dang, P., Eadie, L., To, L. B., Melo, J., Kumar, S., Hughes, T. P., White, D. L.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 604 KB

english, 2008

50

The Relative Distribution of Membranous and Cytoplasmic Met Is a Prognostic Indicator in Stage I and II Colon Cancer

Ginty, F., Adak, S., Can, A., Gerdes, M., Larsen, M., Cline, H., Filkins, R., Pang, Z., Li, Q., Montalto, M. C.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 896 KB

english, 2008

51

Heterogeneous Ribonucleoprotein K and Thymidine Phosphorylase Are Independent Prognostic and Therapeutic Markers for Nasopharyngeal Carcinoma

Chen, L.-C., Hsueh, C., Tsang, N.-M., Liang, Y., Chang, K.-P., Hao, S.-P., Yu, J.-S., Chang, Y.-S.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 431 KB

english, 2008

52

Interaction of Cisplatin with the Human Organic Cation Transporter 2

Filipski, K. K., Loos, W. J., Verweij, J., Sparreboom, A.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 280 KB

english, 2008