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Volume 14; Issue 12
Main
Clinical Cancer Research
Volume 14; Issue 12
Clinical Cancer Research
Volume 14; Issue 12
1
Is There a Role for Circulating Tumor Cells in the Management of Breast Cancer?
Hayes, D. F.
,
Smerage, J.
Journal:
Clinical Cancer Research
Year:
2008
Language:
english
File:
PDF, 309 KB
Your tags:
english, 2008
2
Selective Inhibition of BRCA2-Deficient Mammary Tumor Cell Growth by AZD2281 and Cisplatin
Evers, B.
,
Drost, R.
,
Schut, E.
,
de Bruin, M.
,
van der Burg, E.
,
Derksen, P. W.B.
,
Holstege, H.
,
Liu, X.
,
van Drunen, E.
,
Beverloo, H. B.
,
Smith, G. C.M.
,
Martin, N. M.B.
,
Lau, A.
,
O'Connor, M. J.
,
Jo
Journal:
Clinical Cancer Research
Year:
2008
Language:
english
File:
PDF, 1.20 MB
Your tags:
english, 2008
3
Improved Prediction of Disease Relapse after Radical Prostatectomy through a Panel of Preoperative Blood-Based Biomarkers
Shariat, S. F.
,
Karam, J. A.
,
Walz, J.
,
Roehrborn, C. G.
,
Montorsi, F.
,
Margulis, V.
,
Saad, F.
,
Slawin, K. M.
,
Karakiewicz, P. I.
Journal:
Clinical Cancer Research
Year:
2008
Language:
english
File:
PDF, 189 KB
Your tags:
english, 2008
4
Phase I Study of GTI-2040, an Antisense to Ribonucleotide Reductase, in Combination with High-Dose Cytarabine in Patients with Acute Myeloid Leukemia
Klisovic, R. B.
,
Blum, W.
,
Wei, X.
,
Liu, S.
,
Liu, Z.
,
Xie, Z.
,
Vukosavljevic, T.
,
Kefauver, C.
,
Huynh, L.
,
Pang, J.
,
Zwiebel, J. A.
,
Devine, S.
,
Byrd, J. C.
,
Grever, M. R.
,
Chan, K.
,
Marcucci, G.
Journal:
Clinical Cancer Research
Year:
2008
Language:
english
File:
PDF, 247 KB
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english, 2008
5
A Metastasis Modifier Locus on Human Chromosome 8p in Uveal Melanoma Identified by Integrative Genomic Analysis
Onken, M. D.
,
Worley, L. A.
,
Harbour, J. W.
Journal:
Clinical Cancer Research
Year:
2008
Language:
english
File:
PDF, 744 KB
Your tags:
english, 2008
6
Intraoperative 186Re-Liposome Radionuclide Therapy in a Head and Neck Squamous Cell Carcinoma Xenograft Positive Surgical Margin Model
Wang, S. X.
,
Bao, A.
,
Herrera, S. J.
,
Phillips, W. T.
,
Goins, B.
,
Santoyo, C.
,
Miller, F. R.
,
Otto, R. A.
Journal:
Clinical Cancer Research
Year:
2008
Language:
english
File:
PDF, 342 KB
Your tags:
english, 2008
7
Tumor Vascular Maturation and Improved Drug Delivery Induced by Methylselenocysteine Leads to Therapeutic Synergy with Anticancer Drugs
Bhattacharya, A.
,
Seshadri, M.
,
Oven, S. D.
,
Toth, K.
,
Vaughan, M. M.
,
Rustum, Y. M.
Journal:
Clinical Cancer Research
Year:
2008
Language:
english
File:
PDF, 403 KB
Your tags:
english, 2008
8
Are There Any Ethnic Differences in Molecular Predictors of Erlotinib Efficacy in Advanced Non-Small Cell Lung Cancer?
Ahn, M.-J.
,
Park, B.-B.
,
Ahn, J. S.
,
Kim, S. W.
,
Kim, H.-T.
,
Lee, J. S.
,
Kang, J. H.
,
Cho, J. Y.
,
Song, H. S.
,
Park, S. H.
,
Sohn, C. H.
,
Shin, S. W.
,
Choi, J. H.
,
Ki, C.-S.
,
Park, C. K.
,
Holmes, A. J.
Journal:
Clinical Cancer Research
Year:
2008
Language:
english
File:
PDF, 184 KB
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english, 2008
9
RHAMM, p21 Combined Phenotype Identifies Microsatellite Instability-High Colorectal Cancers with a Highly Adverse Prognosis
Zlobec, I.
,
Baker, K.
,
Terracciano, L. M.
,
Lugli, A.
Journal:
Clinical Cancer Research
Year:
2008
Language:
english
File:
PDF, 427 KB
Your tags:
english, 2008
10
Phase II Study of Dasatinib in Philadelphia Chromosome-Negative Acute and Chronic Myeloid Diseases, Including Systemic Mastocytosis
Verstovsek, S.
,
Tefferi, A.
,
Cortes, J.
,
O'Brien, S.
,
Garcia-Manero, G.
,
Pardanani, A.
,
Akin, C.
,
Faderl, S.
,
Manshouri, T.
,
Thomas, D.
,
Kantarjian, H.
Journal:
Clinical Cancer Research
Year:
2008
Language:
english
File:
PDF, 219 KB
Your tags:
english, 2008
11
BRCA1 and BRCA2 Mutation Prevalence and Clinical Characteristics of a Population-Based Series of Ovarian Cancer Cases from Denmark
Soegaard, M.
,
Kjaer, S. K.
,
Cox, M.
,
Wozniak, E.
,
Hogdall, E.
,
Hogdall, C.
,
Blaakaer, J.
,
Jacobs, I. J.
,
Gayther, S. A.
,
Ramus, S. J.
Journal:
Clinical Cancer Research
Year:
2008
Language:
english
File:
PDF, 195 KB
Your tags:
english, 2008
12
Advances in the Development of Cancer Therapeutics Directed against the RAS-Mitogen-Activated Protein Kinase Pathway
Sebolt-Leopold, J. S.
Journal:
Clinical Cancer Research
Year:
2008
Language:
english
File:
PDF, 295 KB
Your tags:
english, 2008
13
Transforming Growth Factor- Receptor Blockade Augments the Effectiveness of Adoptive T-Cell Therapy of Established Solid Cancers
Wallace, A.
,
Kapoor, V.
,
Sun, J.
,
Mrass, P.
,
Weninger, W.
,
Heitjan, D. F.
,
June, C.
,
Kaiser, L. R.
,
Ling, L. E.
,
Albelda, S. M.
Journal:
Clinical Cancer Research
Year:
2008
Language:
english
File:
PDF, 326 KB
Your tags:
english, 2008
14
The Development of Phase I Cancer Trial Methodologies: the Use of Pharmacokinetic and Pharmacodynamic End Points Sets the Scene for Phase 0 Cancer Clinical Trials
Calvert, A. H.
,
Plummer, R.
Journal:
Clinical Cancer Research
Year:
2008
Language:
english
File:
PDF, 292 KB
Your tags:
english, 2008
15
A Phase II Pharmacodynamic Study of Erlotinib in Patients with Advanced Non-Small Cell Lung Cancer Previously Treated with Platinum-Based Chemotherapy
Felip, E.
,
Rojo, F.
,
Reck, M.
,
Heller, A.
,
Klughammer, B.
,
Sala, G.
,
Cedres, S.
,
Peralta, S.
,
Maacke, H.
,
Foernzler, D.
,
Parera, M.
,
Mocks, J.
,
Saura, C.
,
Gatzemeier, U.
,
Baselga, J.
Journal:
Clinical Cancer Research
Year:
2008
Language:
english
File:
PDF, 213 KB
Your tags:
english, 2008
16
Increase in Brain Tumor Permeability in Glioma-Bearing Rats with Nitric Oxide Donors
Yin, D.
,
Wang, X.
,
Konda, B. M.
,
Ong, J. M.
,
Hu, J.
,
Sacapano, M. R.
,
Ko, M. K.
,
Espinoza, A. J.
,
Irvin, D. K.
,
Shu, Y.
,
Black, K. L.
Journal:
Clinical Cancer Research
Year:
2008
Language:
english
File:
PDF, 498 KB
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english, 2008
17
From the editor
Bates, S. E.
Journal:
Clinical Cancer Research
Year:
2008
Language:
english
File:
PDF, 81 KB
Your tags:
english, 2008
18
Association of p16 Homozygous Deletions with Clinicopathologic Characteristics and EGFR/KRAS/p53 Mutations in Lung Adenocarcinoma
Iwakawa, R.
,
Kohno, T.
,
Anami, Y.
,
Noguchi, M.
,
Suzuki, K.
,
Matsuno, Y.
,
Mishima, K.
,
Nishikawa, R.
,
Tashiro, F.
,
Yokota, J.
Journal:
Clinical Cancer Research
Year:
2008
Language:
english
File:
PDF, 455 KB
Your tags:
english, 2008
19
MDM2 Promoter Polymorphism and Pancreatic Cancer Risk and Prognosis
Asomaning, K.
,
Reid, A. E.
,
Zhou, W.
,
Heist, R. S.
,
Zhai, R.
,
Su, L.
,
Kwak, E. L.
,
Blaszkowsky, L.
,
Zhu, A. X.
,
Ryan, D. P.
,
Christiani, D. C.
,
Liu, G.
Journal:
Clinical Cancer Research
Year:
2008
Language:
english
File:
PDF, 176 KB
Your tags:
english, 2008
20
DNA-Dependent Protein Kinase Is a Therapeutic Target and an Indicator of Poor Prognosis in B-Cell Chronic Lymphocytic Leukemia
Willmore, E.
,
Elliott, S. L.
,
Mainou-Fowler, T.
,
Summerfield, G. P.
,
Jackson, G. H.
,
O'Neill, F.
,
Lowe, C.
,
Carter, A.
,
Harris, R.
,
Pettitt, A. R.
,
Cano-Soumillac, C.
,
Griffin, R. J.
,
Cowell, I. G.
,
A
Journal:
Clinical Cancer Research
Year:
2008
Language:
english
File:
PDF, 381 KB
Your tags:
english, 2008
21
The Ethics of Phase 0 Oncology Trials
Abdoler, E.
,
Taylor, H.
,
Wendler, D.
Journal:
Clinical Cancer Research
Year:
2008
Language:
english
File:
PDF, 102 KB
Your tags:
english, 2008
22
Local Recurrence in Mismatch Repair-Proficient Colon Cancer Predicted by an Infiltrative Tumor Border and Lack of CD8+ Tumor-Infiltrating Lymphocytes
Zlobec, I.
,
Terracciano, L. M.
,
Lugli, A.
Journal:
Clinical Cancer Research
Year:
2008
Language:
english
File:
PDF, 182 KB
Your tags:
english, 2008
23
Patient Perspectives on Phase 0 Clinical Trials
Gutierrez, M.
,
Collyar, D.
Journal:
Clinical Cancer Research
Year:
2008
Language:
english
File:
PDF, 124 KB
Your tags:
english, 2008
24
RCAS/SCL-TVA Animal Model Allows Targeted Delivery of Polyoma Middle T Oncogene to Vascular Endothelial Progenitors In vivo and Results in Hemangioma Development
Sausville, J.
,
Molinolo, A. A.
,
Cheng, X.
,
Frampton, J.
,
Takebe, N.
,
Gutkind, J. S.
,
Feldman, R. A.
Journal:
Clinical Cancer Research
Year:
2008
Language:
english
File:
PDF, 622 KB
Your tags:
english, 2008
25
PTEN Loss Does Not Predict for Response to RAD001 (Everolimus) in a Glioblastoma Orthotopic Xenograft Test Panel
Yang, L.
,
Clarke, M. J.
,
Carlson, B. L.
,
Mladek, A. C.
,
Schroeder, M. A.
,
Decker, P.
,
Wu, W.
,
Kitange, G. J.
,
Grogan, P. T.
,
Goble, J. M.
,
Uhm, J.
,
Galanis, E.
,
Giannini, C.
,
Lane, H. A.
,
James, C. D.
Journal:
Clinical Cancer Research
Year:
2008
Language:
english
File:
PDF, 402 KB
Your tags:
english, 2008
26
Correction: Letters on Computed Tomography Screening for Lung Cancer
Journal:
Clinical Cancer Research
Year:
2008
Language:
english
File:
PDF, 28 KB
Your tags:
english, 2008
27
Phase 0 Trials: An Industry Perspective
Eliopoulos, H.
,
Giranda, V.
,
Carr, R.
,
Tiehen, R.
,
Leahy, T.
,
Gordon, G.
Journal:
Clinical Cancer Research
Year:
2008
Language:
english
File:
PDF, 263 KB
Your tags:
english, 2008
28
Heterogeneity of Drug Target Expression Among Metastatic Lesions: Lessons from a Breast Cancer Autopsy Program
Steeg, P. S.
Journal:
Clinical Cancer Research
Year:
2008
Language:
english
File:
PDF, 261 KB
Your tags:
english, 2008
29
Effect of Interleukin-10 Gene Polymorphisms on Clinical Outcome of Patients with Aggressive Non-Hodgkin's Lymphoma: An Exploratory Study
Kube, D.
,
Hua, T.-D.
,
von Bonin, F.
,
Schoof, N.
,
Zeynalova, S.
,
Kloss, M.
,
Gocht, D.
,
Potthoff, B.
,
Tzvetkov, M.
,
Brockmoller, J.
,
Loffler, M.
,
Pfreundschuh, M.
,
Trumper, L.
Journal:
Clinical Cancer Research
Year:
2008
Language:
english
File:
PDF, 325 KB
Your tags:
english, 2008
30
Leveraging Exploratory Investigational New Drug Studies to Accelerate Drug Development
Jacobson-Kram, D.
,
Mills, G.
Journal:
Clinical Cancer Research
Year:
2008
Language:
english
File:
PDF, 325 KB
Your tags:
english, 2008
31
Down-Regulation of Hedgehog-Interacting Protein through Genetic and Epigenetic Alterations in Human Hepatocellular Carcinoma
Tada, M.
,
Kanai, F.
,
Tanaka, Y.
,
Tateishi, K.
,
Ohta, M.
,
Asaoka, Y.
,
Seto, M.
,
Muroyama, R.
,
Fukai, K.
,
Imazeki, F.
,
Kawabe, T.
,
Yokosuka, O.
,
Omata, M.
Journal:
Clinical Cancer Research
Year:
2008
Language:
english
File:
PDF, 362 KB
Your tags:
english, 2008
32
Intratumoral Coadministration of Hyaluronidase Enzyme and Oncolytic Adenoviruses Enhances Virus Potency in Metastatic Tumor Models
Ganesh, S.
,
Gonzalez-Edick, M.
,
Gibbons, D.
,
Van Roey, M.
,
Jooss, K.
Journal:
Clinical Cancer Research
Year:
2008
Language:
english
File:
PDF, 702 KB
Your tags:
english, 2008
33
Concerted Potent Humoral Immune Responses to Autoantigens Are Associated with Tumor Destruction and Favorable Clinical Outcomes without Autoimmunity
Sittler, T.
,
Zhou, J.
,
Park, J.
,
Yuen, N. K.
,
Sarantopoulos, S.
,
Mollick, J.
,
Salgia, R.
,
Giobbie-Hurder, A.
,
Dranoff, G.
,
Hodi, F. S.
Journal:
Clinical Cancer Research
Year:
2008
Language:
english
File:
PDF, 241 KB
Your tags:
english, 2008
34
T Regulatory Type 1 Cells in Squamous Cell Carcinoma of the Head and Neck: Mechanisms of Suppression and Expansion in Advanced Disease
Bergmann, C.
,
Strauss, L.
,
Wang, Y.
,
Szczepanski, M. J.
,
Lang, S.
,
Johnson, J. T.
,
Whiteside, T. L.
Journal:
Clinical Cancer Research
Year:
2008
Language:
english
File:
PDF, 598 KB
Your tags:
english, 2008
35
Soluble ErbB3 Levels in Bone Marrow and Plasma of Men with Prostate Cancer
Lin, S.-H.
,
Lee, Y.-C.
,
Choueiri, M. B.
,
Wen, S.
,
Mathew, P.
,
Ye, X.
,
Do, K.-A.
,
Navone, N. M.
,
Kim, J.
,
Tu, S.-M.
,
Yu-Lee, L.-Y.
,
Logothetis, C. J.
Journal:
Clinical Cancer Research
Year:
2008
Language:
english
File:
PDF, 280 KB
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english, 2008
36
CIP2A Is Overexpressed in Gastric Cancer and Its Depletion Leads to Impaired Clonogenicity, Senescence, or Differentiation of Tumor Cells
Li, W.
,
Ge, Z.
,
Liu, C.
,
Liu, Z.
,
Bjorkholm, M.
,
Jia, J.
,
Xu, D.
Journal:
Clinical Cancer Research
Year:
2008
Language:
english
File:
PDF, 377 KB
Your tags:
english, 2008
37
Oncologic Phase 0 Trials Incorporating Clinical Pharmacodynamics: from Concept to Patient
Doroshow, J. H.
,
Parchment, R. E.
Journal:
Clinical Cancer Research
Year:
2008
Language:
english
File:
PDF, 249 KB
Your tags:
english, 2008
38
Phosphodiesterase 11A (PDE11A) and Genetic Predisposition to Adrenocortical Tumors
Libe, R.
,
Fratticci, A.
,
Coste, J.
,
Tissier, F.
,
Horvath, A.
,
Ragazzon, B.
,
Rene-Corail, F.
,
Groussin, L.
,
Bertagna, X.
,
Raffin-Sanson, M. L.
,
Stratakis, C. A.
,
Bertherat, J.
Journal:
Clinical Cancer Research
Year:
2008
Language:
english
File:
PDF, 530 KB
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english, 2008
39
Suppression of proHB-EGF Carboxy-Terminal Fragment Nuclear Translocation: A New Molecular Target Therapy for Gastric Cancer
Shimura, T.
,
Kataoka, H.
,
Ogasawara, N.
,
Kubota, E.
,
Sasaki, M.
,
Tanida, S.
,
Joh, T.
Journal:
Clinical Cancer Research
Year:
2008
Language:
english
File:
PDF, 930 KB
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english, 2008
40
Cytokeratin 10 and Cytokeratin 19: Predictive Markers for Poor Prognosis in Hepatocellular Carcinoma Patients after Curative Resection
Yang, X.-R.
,
Xu, Y.
,
Shi, G.-M.
,
Fan, J.
,
Zhou, J.
,
Ji, Y.
,
Sun, H.-C.
,
Qiu, S.-J.
,
Yu, B.
,
Gao, Q.
,
He, Y.-Z.
,
Qin, W.-Z.
,
Chen, R.-X.
,
Yang, G.-H.
,
Wu, B.
,
Lu, Q.
,
Wu, Z.-Q.
,
Tang, Z.-Y.
Journal:
Clinical Cancer Research
Year:
2008
Language:
english
File:
PDF, 1.05 MB
Your tags:
english, 2008
41
Designing Phase 0 Cancer Clinical Trials
Murgo, A. J.
,
Kummar, S.
,
Rubinstein, L.
,
Gutierrez, M.
,
Collins, J.
,
Kinders, R.
,
Parchment, R. E.
,
Ji, J.
,
Steinberg, S. M.
,
Yang, S. X.
,
Hollingshead, M.
,
Chen, A.
,
Helman, L.
,
Wiltrout, R.
,
Tomasz
Journal:
Clinical Cancer Research
Year:
2008
Language:
english
File:
PDF, 758 KB
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english, 2008
42
Association of Megalin Genetic Polymorphisms with Prostate Cancer Risk and Prognosis
Holt, S. K.
,
Karyadi, D. M.
,
Kwon, E. M.
,
Stanford, J. L.
,
Nelson, P. S.
,
Ostrander, E. A.
Journal:
Clinical Cancer Research
Year:
2008
Language:
english
File:
PDF, 192 KB
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english, 2008
43
Oncogenic and Angiogenic Growth Factors Accumulate during Routine Storage of Apheresis Platelet Concentrates
Kanter, J.
,
Khan, S. Y.
,
Kelher, M.
,
Gore, L.
,
Silliman, C. C.
Journal:
Clinical Cancer Research
Year:
2008
Language:
english
File:
PDF, 228 KB
Your tags:
english, 2008
44
Somatic Mutations of JAK1 and JAK3 in Acute Leukemias and Solid Cancers
Jeong, E. G.
,
Kim, M. S.
,
Nam, H. K.
,
Min, C. K.
,
Lee, S.
,
Chung, Y. J.
,
Yoo, N. J.
,
Lee, S. H.
Journal:
Clinical Cancer Research
Year:
2008
Language:
english
File:
PDF, 428 KB
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english, 2008
45
Imaging Immune Response In vivo: Cytolytic Action of Genetically Altered T Cells Directed to Glioblastoma Multiforme
Lazovic, J.
,
Jensen, M. C.
,
Ferkassian, E.
,
Aguilar, B.
,
Raubitschek, A.
,
Jacobs, R. E.
Journal:
Clinical Cancer Research
Year:
2008
Language:
english
File:
PDF, 511 KB
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english, 2008
46
Affibody Molecules for In vivo Characterization of HER2-Positive Tumors by Near-Infrared Imaging
Lee, S. B.
,
Hassan, M.
,
Fisher, R.
,
Chertov, O.
,
Chernomordik, V.
,
Kramer-Marek, G.
,
Gandjbakhche, A.
,
Capala, J.
Journal:
Clinical Cancer Research
Year:
2008
Language:
english
File:
PDF, 746 KB
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english, 2008
47
Tissue-Based Research in Kidney Cancer: Current Challenges and Future Directions
Signoretti, S.
,
Bratslavsky, G.
,
Waldman, F. M.
,
Reuter, V. E.
,
Haaga, J.
,
Merino, M.
,
Thomas, G. V.
,
Pins, M. R.
,
Libermann, T.
,
Gillespie, J.
,
Tomaszewski, J. E.
,
Compton, C. C.
,
Hruszkewycz, A.
,
Li
Journal:
Clinical Cancer Research
Year:
2008
Language:
english
File:
PDF, 205 KB
Your tags:
english, 2008
48
ssDNA-Binding Protein 2 Is Frequently Hypermethylated and Suppresses Cell Growth in Human Prostate Cancer
Liu, J.-W.
,
Nagpal, J. K.
,
Sun, W.
,
Lee, J.
,
Kim, M. S.
,
Ostrow, K. L.
,
Zhou, S.
,
Jeronimo, C.
,
Henrique, R.
,
Van Criekinge, W.
,
Moon, C. S.
,
Califano, J. A.
,
Trink, B.
,
Sidransky, D.
Journal:
Clinical Cancer Research
Year:
2008
Language:
english
File:
PDF, 390 KB
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english, 2008
49
Dasatinib Cellular Uptake and Efflux in Chronic Myeloid Leukemia Cells: Therapeutic Implications
Hiwase, D. K.
,
Saunders, V.
,
Hewett, D.
,
Frede, A.
,
Zrim, S.
,
Dang, P.
,
Eadie, L.
,
To, L. B.
,
Melo, J.
,
Kumar, S.
,
Hughes, T. P.
,
White, D. L.
Journal:
Clinical Cancer Research
Year:
2008
Language:
english
File:
PDF, 604 KB
Your tags:
english, 2008
50
The Relative Distribution of Membranous and Cytoplasmic Met Is a Prognostic Indicator in Stage I and II Colon Cancer
Ginty, F.
,
Adak, S.
,
Can, A.
,
Gerdes, M.
,
Larsen, M.
,
Cline, H.
,
Filkins, R.
,
Pang, Z.
,
Li, Q.
,
Montalto, M. C.
Journal:
Clinical Cancer Research
Year:
2008
Language:
english
File:
PDF, 896 KB
Your tags:
english, 2008
51
Heterogeneous Ribonucleoprotein K and Thymidine Phosphorylase Are Independent Prognostic and Therapeutic Markers for Nasopharyngeal Carcinoma
Chen, L.-C.
,
Hsueh, C.
,
Tsang, N.-M.
,
Liang, Y.
,
Chang, K.-P.
,
Hao, S.-P.
,
Yu, J.-S.
,
Chang, Y.-S.
Journal:
Clinical Cancer Research
Year:
2008
Language:
english
File:
PDF, 431 KB
Your tags:
english, 2008
52
Interaction of Cisplatin with the Human Organic Cation Transporter 2
Filipski, K. K.
,
Loos, W. J.
,
Verweij, J.
,
Sparreboom, A.
Journal:
Clinical Cancer Research
Year:
2008
Language:
english
File:
PDF, 280 KB
Your tags:
english, 2008
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