Volume 14; Issue 22

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Clinical Cancer Research
Volume 14; Issue 22

Clinical Cancer Research

Volume 14; Issue 22

1

Humanized Radioiodinated Minibody For Imaging of Prostate Stem Cell Antigen-Expressing Tumors

Leyton, J. V., Olafsen, T., Lepin, E. J., Hahm, S., Bauer, K. B., Reiter, R. E., Wu, A. M.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 384 KB

english, 2008

2

Phase I Study of Copper-Binding Agent ATN-224 in Patients with Advanced Solid Tumors

Lowndes, S. A., Adams, A., Timms, A., Fisher, N., Smythe, J., Watt, S. M., Joel, S., Donate, F., Hayward, C., Reich, S., Middleton, M., Mazar, A., Harris, A. L.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 326 KB

english, 2008

3

G-Quadruplex Ligand RHPS4 Potentiates the Antitumor Activity of Camptothecins in Preclinical Models of Solid Tumors

Leonetti, C., Scarsella, M., Riggio, G., Rizzo, A., Salvati, E., D'Incalci, M., Staszewsky, L., Frapolli, R., Stevens, M. F., Stoppacciaro, A., Mottolese, M., Antoniani, B., Gilson, E., Zupi, G., Biro

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 604 KB

english, 2008

4

Clonal Evolution in t(14;18)-Positive Follicular Lymphoma, Evidence for Multiple Common Pathways, and Frequent Parallel Clonal Evolution

d'Amore, F., Chan, E., Iqbal, J., Geng, H., Young, K., Xiao, L., Hess, M. M., Sanger, W. G., Smith, L., Wiuf, C., Hagberg, O., Fu, K., Chan, W. C., Dave, B. J.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 663 KB

english, 2008

5

The N Staging System in Nasopharyngeal Carcinoma with Radiation Therapy Oncology Group Guidelines for Lymph Node Levels Based on Magnetic Resonance Imaging

Mao, Y.-P., Liang, S.-B., Liu, L.-Z., Chen, Y., Sun, Y., Tang, L.-L., Tian, L., Lin, A.-H., Liu, M.-Z., Li, L., Ma, J.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 350 KB

english, 2008

6

Human Telomerase Reverse Transcriptase Activated by E6 Oncoprotein Is Required for Human Papillomavirus-16/18-Infected Lung Tumorigenesis

Cheng, Y.-W., Wu, T.-C., Chen, C.-Y., Chou, M.-C., Ko, J.-L., Lee, H.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 348 KB

english, 2008

7

Clinical and Pharmacologic Study of the Novel Prodrug Delimotecan (MEN 4901/T-0128) in Patients with Solid Tumors

Veltkamp, S. A., Witteveen, E. O., Capriati, A., Crea, A., Animati, F., Voogel-Fuchs, M., van den Heuvel, I. J.G.M., Beijnen, J. H., Voest, E. E., Schellens, J. H.M.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 366 KB

english, 2008

8

Prognostic Significance of Epithelial-Mesenchymal and Mesenchymal-Epithelial Transition Protein Expression in Non-Small Cell Lung Cancer

Soltermann, A., Tischler, V., Arbogast, S., Braun, J., Probst-Hensch, N., Weder, W., Moch, H., Kristiansen, G.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 452 KB

english, 2008

9

Nonclinical Antiangiogenesis and Antitumor Activities of Axitinib (AG-013736), an Oral, Potent, and Selective Inhibitor of Vascular Endothelial Growth Factor Receptor Tyrosine Kinases 1, 2, 3

Hu-Lowe, D. D., Zou, H. Y., Grazzini, M. L., Hallin, M. E., Wickman, G. R., Amundson, K., Chen, J. H., Rewolinski, D. A., Yamazaki, S., Wu, E. Y., McTigue, M. A., Murray, B. W., Kania, R. S., O'Connor

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 580 KB

english, 2008

10

Irinophore C, a Novel Nanoformulation of Irinotecan, Alters Tumor Vascular Function and Enhances the Distribution of 5-Fluorouracil and Doxorubicin

Baker, J. H.E., Lam, J., Kyle, A. H., Sy, J., Oliver, T., Co, S. J., Dragowska, W. H., Ramsay, E., Anantha, M., Ruth, T. J., Adam, M. J., Yung, A., Kozlowski, P., Minchinton, A. I., Ng, S. S.W., Bally

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 840 KB

english, 2008

11

Ubiquitin Proteasome System Stress Underlies Synergistic Killing of Ovarian Cancer Cells by Bortezomib and a Novel HDAC6 Inhibitor

Bazzaro, M., Lin, Z., Santillan, A., Lee, M. K., Wang, M.-C., Chan, K. C., Bristow, R. E., Mazitschek, R., Bradner, J., Roden, R. B.S.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 579 KB

english, 2008

12

Diagnostic Markers for Ovarian Cancer Screening: Not Ready for Routine Clinical Use

Coates, R. J., Kolor, K., Stewart, S. L., Richardson, L. C.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 104 KB

english, 2008

13

The Importance of Test Positive Predictive Value in Ovarian Cancer Screening

Greene, M. H., Feng, Z., Gail, M. H.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 95 KB

english, 2008

14

Nuclear Factor- B Modulation in Patients Undergoing Induction Chemotherapy for Acute Myelogenous Leukemia

Strair, R. K., Gharibo, M., Schaar, D., Rubin, A., Harrison, J., Aisner, J., Lin, H.-C., Lin, Y., Goodell, L., Anand, M., Balsara, B., Dudek, L., Rabson, A., Medina, D. J.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 382 KB

english, 2008

15

Myelotoxicity in Cancer Patients Treated with Chemotherapy: Negative or Positive Prognostic Factor?

Koutras, A. K., Kalofonos, H. P.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 84 KB

english, 2008

16

An Orthotopic Murine Model of Sinonasal Malignancy

Gelbard, A., Kupferman, M. E., Jasser, S. A., Chen, W., El-Naggar, A. K., Myers, J. N., Hanna, E. Y.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 1.21 MB

english, 2008

17

Circulating Biomarkers of Cell Death After Treatment with the BH-3 Mimetic ABT-737 in a Preclinical Model of Small-Cell Lung Cancer

Micha, D., Cummings, J., Shoemaker, A., Elmore, S., Foster, K., Greaves, M., Ward, T., Rosenberg, S., Dive, C., Simpson, K.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 226 KB

english, 2008

18

[18F]Fluorothymidine Positron Emission Tomography before and 7 Days after Gefitinib Treatment Predicts Response in Patients with Advanced Adenocarcinoma of the Lung

Sohn, H.-J., Yang, Y.-J., Ryu, J.-S., Oh, S. J., Im, K. C., Moon, D. H., Lee, D. H., Suh, C., Lee, J.-S., Kim, S.-W.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 390 KB

english, 2008

19

The Use of Genetic Markers to Identify Lung Cancer in Fine Needle Aspiration Samples

Gill, R. K., Vazquez, M. F., Kramer, A., Hames, M., Zhang, L., Heselmeyer-Haddad, K., Ried, T., Shilo, K., Henschke, C., Yankelevitz, D., Jen, J.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 316 KB

english, 2008

20

Prognostic Relevance of Occult Nodal Micrometastases and Circulating Tumor Cells in Colorectal Cancer in a Prospective Multicenter Trial

Koyanagi, K., Bilchik, A. J., Saha, S., Turner, R. R., Wiese, D., McCarter, M., Shen, P., Deacon, L., Elashoff, D., Hoon, D. S.B.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 244 KB

english, 2008

21

Enhanced Antitumor Efficacy of Clinical-Grade Vasculature-Targeted Liposomal Doxorubicin

Pastorino, F., Di Paolo, D., Piccardi, F., Nico, B., Ribatti, D., Daga, A., Baio, G., Neumaier, C. E., Brignole, C., Loi, M., Marimpietri, D., Pagnan, G., Cilli, M., Lepekhin, E. A., Garde, S. V., Lon

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 910 KB

english, 2008

22

Quantitative Analysis of Vascular Endothelial Growth Factor in Liver Metastases from Pancreatic Carcinoma as a Predictor of Chemotherapeutic Effect and Prognosis

Tawada, K., Ishihara, T., Kobayashi, A., Yamaguchi, T., Tsuyuguchi, T., Matsuyama, M., Yokosuka, O.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 361 KB

english, 2008

23

Ovarian Cancer Early Detection Claims Are Biased

McIntosh, M., Anderson, G., Drescher, C., Hanash, S., Urban, N., Brown, P., Gambhir, S. S., Coukos, G., Laird, P. W., Nelson, B., Palmer, C.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 83 KB

english, 2008

24

Endosialin Protein Expression and Therapeutic Target Potential in Human Solid Tumors: Sarcoma versus Carcinoma

Rouleau, C., Curiel, M., Weber, W., Smale, R., Kurtzberg, L., Mascarello, J., Berger, C., Wallar, G., Bagley, R., Honma, N., Hasegawa, K., Ishida, I., Kataoka, S., Thurberg, B. L., Mehraein, K., Horte

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 1.42 MB

english, 2008

25

Activation of the Osteopontin/Matrix Metalloproteinase-9 Pathway Correlates with Prostate Cancer Progression

Castellano, G., Malaponte, G., Mazzarino, M. C., Figini, M., Marchese, F., Gangemi, P., Travali, S., Stivala, F., Canevari, S., Libra, M.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 766 KB

english, 2008

26

Methylation of Tip30 Promoter Is Associated with Poor Prognosis in Human Hepatocellular Carcinoma

Lu, B., Ma, Y., Wu, G., Tong, X., Guo, H., Liang, A., Cong, W., Liu, C., Wang, H., Wu, M., Zhao, J., Guo, Y.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 562 KB

english, 2008

27

Prediction of Recurrence-Free Survival in Postoperative Non-Small Cell Lung Cancer Patients by Using an Integrated Model of Clinical Information and Gene Expression

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 576 KB

english, 2008

28

Predictive Value of Plasma Hepatocyte Growth Factor/Scatter Factor Levels in Patients with Clinically Localized Prostate Cancer

Gupta, A., Karakiewicz, P. I., Roehrborn, C. G., Lotan, Y., Zlotta, A. R., Shariat, S. F.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 117 KB

english, 2008

29

Integrin v 3-Targeted Radioimmunotherapy of Glioblastoma Multiforme

Veeravagu, A., Liu, Z., Niu, G., Chen, K., Jia, B., Cai, W., Jin, C., Hsu, A. R., Connolly, A. J., Tse, V., Wang, F., Chen, X.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 746 KB

english, 2008

30

Surgery followed by Persistence of High-Grade Squamous Intraepithelial Lesions Is Associated with the Induction of a Dysfunctional HPV16-Specific T-Cell Response

de Vos van Steenwijk, P. J., Piersma, S. J., Welters, M. J.P., van der Hulst, J. M., Fleuren, G., Hellebrekers, B. W.J., Kenter, G. G., van der Burg, S. H.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 401 KB

english, 2008

31

Bortezomib-Mediated Inhibition of Steroid Receptor Coactivator-3 Degradation Leads to Activated Akt

Ayala, G., Yan, J., Li, R., Ding, Y., Thompson, T. C., Mims, M. P., Hayes, T. G., MacDonnell, V., Lynch, R. G., Frolov, A., Miles, B. J., Wheeler, T. M., Harper, J. W., Tsai, M.-J., Ittmann, M. M., Ka

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 608 KB

english, 2008

32

Diabodies Targeting Epithelial Membrane Protein 2 Reduce Tumorigenicity of Human Endometrial Cancer Cell Lines

Shimazaki, K., Lepin, E. J., Wei, B., Nagy, A. K., Coulam, C. P., Mareninov, S., Fu, M., Wu, A. M., Marks, J. D., Braun, J., Gordon, L. K., Wadehra, M.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 875 KB

english, 2008

33

Molecular Imaging of Therapeutic Response to Epidermal Growth Factor Receptor Blockade in Colorectal Cancer

Manning, H. C., Merchant, N. B., Foutch, A. C., Virostko, J. M., Wyatt, S. K., Shah, C., McKinley, E. T., Xie, J., Mutic, N. J., Washington, M. K., LaFleur, B., Tantawy, M. N., Peterson, T. E., Ansari

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 762 KB

english, 2008

34

Monoclonal Antibody CC188 Binds a Carbohydrate Epitope Expressed on the Surface of Both Colorectal Cancer Stem Cells and their Differentiated Progeny

Xu, M., Yuan, Y., Xia, Y., Achilefu, S.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 820 KB

english, 2008

35

Loss of Nuclear p27 Expression and Its Prognostic Role in Relation to Cyclin E and p53 Mutation in Gastroenteropancreatic Neuroendocrine Tumors

Grabowski, P., Schrader, J., Wagner, J., Horsch, D., Arnold, R., Arnold, C. N., Georgieva, I., Stein, H., Zeitz, M., Daniel, P. T., Sturm, I.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 490 KB

english, 2008

36

Relationship Between Tumor and Plasma Levels of hTERT mRNA in Patients with Colorectal Cancer: Implications for Monitoring of Neoplastic Disease

Terrin, L., Rampazzo, E., Pucciarelli, S., Agostini, M., Bertorelle, R., Esposito, G., DelBianco, P., Nitti, D., De Rossi, A.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 429 KB

english, 2008

37

Proliferation Imaging to Measure Early Cancer Response to Targeted Therapy

Mankoff, D. A., Eary, J. F.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 162 KB

english, 2008

38

Induction of Both CD8+ and CD4+ T-Cell-Mediated Responses in Colorectal Cancer Patients by Colon Antigen-1

Maccalli, C., Di Cristanziano, V., Fodale, V., Corsi, D., D'Agostino, G., Petrangeli, V., Laurenti, L., Guida, S., Mazzocchi, A., Arienti, F., Perrone, M. P., Castelli, C., Rivoltini, L., Zagonel, V.,

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 464 KB

english, 2008

39

Microtubule Active Agents: Beyond the Taxane Frontier

Morris, P. G., Fornier, M. N.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 314 KB

english, 2008

40

Vaccination of Renal Cell Cancer Patients with Modified Vaccinia Ankara Delivering Tumor Antigen 5T4 (TroVax) Administered with Interleukin 2: A Phase II Trial

Amato, R. J., Shingler, W., Naylor, S., Jac, J., Willis, J., Saxena, S., Hernandez-McClain, J., Harrop, R.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 327 KB

english, 2008

41

Identification of the Molecular Mechanisms for Dedifferentiation at the Invasion Front of Colorectal Cancer by a Gene Expression Analysis

Oku, Y., Shimoji, T., Takifuji, K., Hotta, T., Yokoyama, S., Matsuda, K., Higashiguchi, T., Tominaga, T., Nasu, T., Tamura, K., Matsuura, M., Miyata, S., Kato, Y., Yamaue, H., Miki, Y.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 809 KB

english, 2008

42

Acquired Resistance to Epidermal Growth Factor Receptor Kinase Inhibitors Associated with a Novel T854A Mutation in a Patient with EGFR-Mutant Lung Adenocarcinoma

Bean, J., Riely, G. J., Balak, M., Marks, J. L., Ladanyi, M., Miller, V. A., Pao, W.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 5.33 MB

english, 2008

43

Vascular Endothelial Growth Factor C Stimulates Progression of Human Gastric Cancer via Both Autocrine and Paracrine Mechanisms

Kodama, M., Kitadai, Y., Tanaka, M., Kuwai, T., Tanaka, S., Oue, N., Yasui, W., Chayama, K.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 1.07 MB

english, 2008

44

Role of the Erythropoietin Receptor in ETV6/RUNX1-Positive Acute Lymphoblastic Leukemia

Inthal, A., Krapf, G., Beck, D., Joas, R., Kauer, M. O., Orel, L., Fuka, G., Mann, G., Panzer-Grumayer, E. R.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 407 KB

english, 2008

45

Novel Jet-Injection Technology for Nonviral Intratumoral Gene Transfer in Patients with Melanoma and Breast Cancer

Walther, W., Siegel, R., Kobelt, D., Knosel, T., Dietel, M., Bembenek, A., Aumann, J., Schleef, M., Baier, R., Stein, U., Schlag, P. M.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 521 KB

english, 2008

46

Overexpression of Indoleamine 2,3-Dioxygenase in Human Endometrial Carcinoma Cells Induces Rapid Tumor Growth in a Mouse Xenograft Model

Yoshida, N., Ino, K., Ishida, Y., Kajiyama, H., Yamamoto, E., Shibata, K., Terauchi, M., Nawa, A., Akimoto, H., Takikawa, O., Isobe, K.-i., Kikkawa, F.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 424 KB

english, 2008

47

Relapse-Free Survival in Breast Cancer Patients Is Associated with a Gene Expression Signature Characteristic for Inflammatory Breast Cancer

Van Laere, S., Beissbarth, T., Van der Auwera, I., Van den Eynden, G., Trinh, X. B., Elst, H., Van Hummelen, P., van Dam, P., Van Marck, E., Vermeulen, P., Dirix, L.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 418 KB

english, 2008

48

Leukemia-Associated Antigens Are Critical for the Proliferation of Acute Myeloid Leukemia Cells

Greiner, J., Bullinger, L., Guinn, B.-a., Dohner, H., Schmitt, M.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 283 KB

english, 2008

49

Reply to the Letters to the Editor from Greene et al.

Mor, G., Schwartz, P. E., Yu, H.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 104 KB

english, 2008

50

Polymorphisms and Clinical Outcome in Recurrent Ovarian Cancer Treated with Cyclophosphamide and Bevacizumab

Schultheis, A. M., Lurje, G., Rhodes, K. E., Zhang, W., Yang, D., Garcia, A. A., Morgan, R., Gandara, D., Scudder, S., Oza, A., Hirte, H., Fleming, G., Roman, L., Lenz, H.-J.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 330 KB

english, 2008

51

Genetic Analysis of Cancer-Implicated MicroRNA in Ovarian Cancer

Bearfoot, J. L., Choong, D. Y.H., Gorringe, K. L., Campbell, I. G.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 204 KB

english, 2008

52

High Risk for Ovarian Cancer in a Prospective Series Is Restricted to BRCA1/2 Mutation Carriers

Maehle, L., Apold, J., Paulsen, T., Hagen, B., Lovslett, K., Fiane, B., Van Ghelue, M., Clark, N., Moller, P.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 154 KB

english, 2008

53

Loss of Histone H4K20 Trimethylation Occurs in Preneoplasia and Influences Prognosis of Non-Small Cell Lung Cancer

Van Den Broeck, A., Brambilla, E., Moro-Sibilot, D., Lantuejoul, S., Brambilla, C., Eymin, B., Khochbin, S., Gazzeri, S.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 654 KB

english, 2008

54

Tumor Infection by Oncolytic Reovirus Primes Adaptive Antitumor Immunity

Prestwich, R. J., Errington, F., Ilett, E. J., Morgan, R. S.M., Scott, K. J., Kottke, T., Thompson, J., Morrison, E. E., Harrington, K. J., Pandha, H. S., Selby, P. J., Vile, R. G., Melcher, A. A.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 433 KB

english, 2008

55

Preferential Tumor Targeting and Selective Tumor Cell Cytotoxicity of 5-[131/125I]Iodo-4'-Thio-2'-Deoxyuridine

Morgenroth, A., Deisenhofer, S., Glatting, G., Kunkel, F. H-G., Dinger, C., Zlatopolskiy, B., Vogg, A. T.J., Kull, T., Reske, S. N.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 511 KB

english, 2008