Volume 14; Issue 3

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Clinical Cancer Research
Volume 14; Issue 3

Clinical Cancer Research

Volume 14; Issue 3

1

Tolerability, Pharmacodynamics, and Pharmacokinetics Studies of Depsipeptide (Romidepsin) in Patients with Acute Myelogenous Leukemia or Advanced Myelodysplastic Syndromes

Klimek, V. M., Fircanis, S., Maslak, P., Guernah, I., Baum, M., Wu, N., Panageas, K., Wright, J. J., Pandolfi, P. P., Nimer, S. D.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 188 KB

english, 2008

2

Imaging Epidermal Growth Factor Receptor Expression In vivo: Pharmacokinetic and Biodistribution Characterization of a Bioconjugated Quantum Dot Nanoprobe

Diagaradjane, P., Orenstein-Cardona, J. M., E. Colon-Casasnovas, N., Deorukhkar, A., Shentu, S., Kuno, N., Schwartz, D. L., Gelovani, J. G., Krishnan, S.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 952 KB

english, 2008

3

Combined Clinical Trial Results of a HER2/neu (E75) Vaccine for the Prevention of Recurrence in High-Risk Breast Cancer Patients: U.S. Military Cancer Institute Clinical Trials Group Study I-01 and I-02

Peoples, G. E., Holmes, J. P., Hueman, M. T., Mittendorf, E. A., Amin, A., Khoo, S., Dehqanzada, Z. A., Gurney, J. M., Woll, M. M., Ryan, G. B., Storrer, C. E., Craig, D., Ioannides, C. G., Ponniah, S

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 219 KB

english, 2008

4

A Single-Nucleotide Polymorphism in the Aromatase Gene Is Associated with the Efficacy of the Aromatase Inhibitor Letrozole in Advanced Breast Carcinoma

Colomer, R., Monzo, M., Tusquets, I., Rifa, J., Baena, J. M., Barnadas, A., Calvo, L., Carabantes, F., Crespo, C., Munoz, M., Llombart, A., Plazaola, A., Artells, R., Gilabert, M., Lloveras, B., Alba,

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 182 KB

english, 2008

5

Reduction of Glucose Metabolic Activity Is More Accurate than Change in Size at Predicting Histopathologic Response to Neoadjuvant Therapy in High-Grade Soft-Tissue Sarcomas

Evilevitch, V., Weber, W. A., Tap, W. D., Allen-Auerbach, M., Chow, K., Nelson, S. D., Eilber, F. R., Eckardt, J. J., Elashoff, R. M., Phelps, M. E., Czernin, J., Eilber, F. C.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 307 KB

english, 2008

6

Development of a Multiplex RNA Urine Test for the Detection and Stratification of Transitional Cell Carcinoma of the Bladder

Holyoake, A., O'Sullivan, P., Pollock, R., Best, T., Watanabe, J., Kajita, Y., Matsui, Y., Ito, M., Nishiyama, H., Kerr, N., da Silva Tatley, F., Cambridge, L., Toro, T., Ogawa, O., Guilford, P.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 269 KB

english, 2008

7

Endogenous Vascular Endothelial Growth Factor-C Expression Is Associated with Decreased Drug Responsiveness in Childhood Acute Myeloid Leukemia

de Jonge, H. J.M., Weidenaar, A. C., ter Elst, A., Boezen, H. M., Scherpen, F. J.G., Bouma-ter Steege, J. C.A., Kaspers, G. J.L., Goemans, B. F., Creutzig, U., Zimmermann, M., Kamps, W. A., de Bont, E

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 210 KB

english, 2008

8

Effect of Melanoma on Immune Function in the Regional Lymph Node Basin

Negin, B., Panka, D., Wang, W., Siddiqui, M., Tawa, N., Mullen, J., Tahan, S., Mandato, L., Polivy, A., Mier, J., Atkins, M.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 305 KB

english, 2008

9

An Exploratory Study of Systemic Administration of the Toll-like Receptor-7 Agonist 852A in Patients with Refractory Metastatic Melanoma

Dummer, R., Hauschild, A., Becker, J. C., Grob, J.-J., Schadendorf, D., Tebbs, V., Skalsky, J., Kaehler, K. C., Moosbauer, S., Clark, R., Meng, T.-C., Urosevic, M.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 371 KB

english, 2008

10

Molecular Targeting and Treatment of Composite EGFR and EGFRvIII-Positive Gliomas Using Boronated Monoclonal Antibodies

Yang, W., Wu, G., Barth, R. F., Swindall, M. R., Bandyopadhyaya, A. K., Tjarks, W., Tordoff, K., Moeschberger, M., Sferra, T. J., Binns, P. J., Riley, K. J., Ciesielski, M. J., Fenstermaker, R. A., Wi

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 345 KB

english, 2008

11

Aberrant Expression of Connexin 26 Is Associated with Lung Metastasis of Colorectal Cancer

Ezumi, K., Yamamoto, H., Murata, K., Higashiyama, M., Damdinsuren, B., Nakamura, Y., Kyo, N., Okami, J., Ngan, C. Y., Takemasa, I., Ikeda, M., Sekimoto, M., Matsuura, N., Nojima, H., Monden, M.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 702 KB

english, 2008

12

Enhanced In vitro and In vivo Cytotoxicity of Combined Reovirus and Radiotherapy

Twigger, K., Vidal, L., White, C. L., De Bono, J. S., Bhide, S., Coffey, M., Thompson, B., Vile, R. G., Heinemann, L., Pandha, H. S., Errington, F., Melcher, A. A., Harrington, K. J.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 1.54 MB

english, 2008

13

Use of a Combination of Approaches to Identify and Validate Relevant Tumor-Associated Antigens and Their Corresponding Autoantibodies in Ovarian Cancer Patients

Gagnon, A., Kim, J.-H., Schorge, J. O., Ye, B., Liu, B., Hasselblatt, K., Welch, W. R., Bandera, C. A., Mok, S. C.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 906 KB

english, 2008

14

Effective Treatment of Established Human Breast Tumor Xenografts in Immunodeficient Mice with a Single Dose of the -Emitting Radioisotope Astatine-211 Conjugated to Anti-HER2/neu Diabodies

Robinson, M. K., Shaller, C., Garmestani, K., Plascjak, P. S., Hodge, K. M., Yuan, Q.-A., Marks, J. D., Waldmann, T. A., Brechbiel, M. W., Adams, G. P.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 251 KB

english, 2008

15

Tumor-Infiltrated Immune Response Correlates with Alterations in the Apoptotic and Cell Cycle Pathways in Hodgkin and Reed-Sternberg Cells

Alvaro, T., Lejeune, M., Garcia, J. F., Salvado, Ma. T., Lopez, C., Bosch, R., Jaen, J., Escriva, P., Pons, L. E.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 203 KB

english, 2008

16

Focal Adhesion Kinase: Targeting Adhesion Signaling Pathways for Therapeutic Intervention

Parsons, J. T., Slack-Davis, J., Tilghman, R., Roberts, W. G.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 230 KB

english, 2008

17

Serum C-Reactive Protein as Independent Prognostic Variable in Patients with Ovarian Cancer

Hefler, L. A., Concin, N., Hofstetter, G., Marth, C., Mustea, A., Sehouli, J., Zeillinger, R., Leipold, H., Lass, H., Grimm, C., Tempfer, C. B., Reinthaller, A.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 174 KB

english, 2008

18

Follistatin as an Inhibitor of Experimental Metastasis

Talmadge, J. E.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 214 KB

english, 2008

19

A Phase I Study of OGX-011, a 2'-Methoxyethyl Phosphorothioate Antisense to Clusterin, in Combination with Docetaxel in Patients with Advanced Cancer

Chi, K. N., Siu, L. L., Hirte, H., Hotte, S. J., Knox, J., Kollmansberger, C., Gleave, M., Guns, E., Powers, J., Walsh, W., Tu, D., Eisenhauer, E.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 306 KB

english, 2008

20

Inhibition of I B Kinase Subunit 2 in Cutaneous T-Cell Lymphoma Down-Regulates Nuclear Factor- B Constitutive Activation, Induces Cell Death, and Potentiates the Apoptotic Response to Antineoplastic Chemotherapeutic Agents

Sors, A., Jean-Louis, F., Begue, E., Parmentier, L., Dubertret, L., Dreano, M., Courtois, G., Bachelez, H., Michel, L.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 1.32 MB

english, 2008

21

Effective Inhibition of the Epidermal Growth Factor/Epidermal Growth Factor Receptor Binding by Anti-Epidermal Growth Factor Antibodies Is Related to Better Survival in Advanced Non-Small-Cell Lung Cancer Patients Treated with the Epidermal Growth Factor Cancer Vaccine

Garcia, B., Neninger, E., de la Torre, A., Leonard, I., Martinez, R., Viada, C., Gonzalez, G., Mazorra, Z., Lage, A., Crombet, T.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 315 KB

english, 2008

22

Targeting Akt and Heat Shock Protein 90 Produces Synergistic Multiple Myeloma Cell Cytotoxicity in the Bone Marrow Microenvironment

Huston, A., Leleu, X., Jia, X., Moreau, A.-S., Ngo, H. T., Runnels, J., Anderson, J., Alsayed, Y., Roccaro, A., Vallet, S., Hatjiharissi, E., Tai, Y.-T., Sportelli, P., Munshi, N., Richardson, P., Hid

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 561 KB

english, 2008

23

Activation of CCR9/CCL25 in Cutaneous Melanoma Mediates Preferential Metastasis to the Small Intestine

Amersi, F. F., Terando, A. M., Goto, Y., Scolyer, R. A., Thompson, J. F., Tran, A. N., Faries, M. B., Morton, D. L., Hoon, D. S.B.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 491 KB

english, 2008

24

Immune Function Abnormalities in Peripheral Blood Mononuclear Cell Cytokine Expression Differentiates Stages of Cutaneous T-Cell Lymphoma/Mycosis Fungoides

Chong, B. F., Wilson, A. J., Gibson, H. M., Hafner, M. S., Luo, Y., Hedgcock, C. J., Wong, H. K.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 622 KB

english, 2008

25

Association between Phosphatidylinositol 3-Kinase Regulatory Subunit p85 Met326Ile Genetic Polymorphism and Colon Cancer Risk

Li, L., Plummer, S. J., Thompson, C. L., Tucker, T. C., Casey, G.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 194 KB

english, 2008

26

In vitro and In vivo Radiosensitization Induced by the DNA Methylating Agent Temozolomide

Kil, W. J., Cerna, D., Burgan, W. E., Beam, K., Carter, D., Steeg, P. S., Tofilon, P. J., Camphausen, K.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 488 KB

english, 2008

27

Thymidylate Synthase and Methylenetetrahydrofolate Reductase Gene Polymorphisms and Toxicity to Capecitabine in Advanced Colorectal Cancer Patients

Sharma, R., Hoskins, J. M., Rivory, L. P., Zucknick, M., London, R., Liddle, C., Clarke, S. J.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 392 KB

english, 2008

28

WP1066, a Novel JAK2 Inhibitor, Suppresses Proliferation and Induces Apoptosis in Erythroid Human Cells Carrying the JAK2 V617F Mutation

Verstovsek, S., Manshouri, T., Quintas-Cardama, A., Harris, D., Cortes, J., Giles, F. J., Kantarjian, H., Priebe, W., Estrov, Z.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 595 KB

english, 2008

29

Prognostic Value of CCN3 in Osteosarcoma

Perbal, B., Zuntini, M., Zambelli, D., Serra, M., Sciandra, M., Cantiani, L., Lucarelli, E., Picci, P., Scotlandi, K.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 663 KB

english, 2008

30

Polycyclic Aromatic Hydrocarbon-DNA Adducts in Prostate and Biochemical Recurrence after Prostatectomy

Rybicki, B. A., Neslund-Dudas, C., Bock, C. H., Rundle, A., Savera, A. T., Yang, J. J., Nock, N. L., Tang, D.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 344 KB

english, 2008

31

Higher Expression of the Androgen-Regulated Gene PSA/HK3 mRNA in Prostate Cancer Tissues Predicts Biochemical Recurrence-Free Survival

Sterbis, J. R., Gao, C., Furusato, B., Chen, Y., Shaheduzzaman, S., Ravindranath, L., Osborn, D. J., Rosner, I. L., Dobi, A., McLeod, D. G., Sesterhenn, I. A., Srivastava, S., Cullen, J., Petrovics, G

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 245 KB

english, 2008

32

Function of Heparanase in Prostate Tumorigenesis: Potential for Therapy

Lerner, I., Baraz, L., Pikarsky, E., Meirovitz, A., Edovitsky, E., Peretz, T., Vlodavsky, I., Elkin, M.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 584 KB

english, 2008

33

T Cell Receptor Genotyping and HOXA/TLX1 Expression Define Three T Lymphoblastic Lymphoma Subsets which Might Affect Clinical Outcome

Baleydier, F., Decouvelaere, A.-V., Bergeron, J., Gaulard, P., Canioni, D., Bertrand, Y., Lepretre, S., Petit, B., Dombret, H., Beldjord, K., Molina, T., Asnafi, V., Macintyre, E.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 357 KB

english, 2008

34

Progression and Tumor Heterogeneity Analysis in Early Rectal Cancer

Lips, E. H., van Eijk, R., de Graaf, E. J.R., Doornebosch, P. G., de Miranda, N. F.C.C., Oosting, J., Karsten, T., Eilers, P. H.C., Tollenaar, R. A.E.M., van Wezel, T., Morreau, H.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 451 KB

english, 2008

35

A Phase 1 Pharmacokinetic and Pharmacodynamic Study of the Histone Deacetylase Inhibitor Belinostat in Patients with Advanced Solid Tumors

Steele, N. L., Plumb, J. A., Vidal, L., Tjornelund, J., Knoblauch, P., Rasmussen, A., Ooi, C. E., Buhl-Jensen, P., Brown, R., Evans, T.R. J., DeBono, J. S.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 350 KB

english, 2008

36

CCR9 Homes Metastatic Melanoma Cells to the Small Bowel

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 125 KB

english, 2008

37

Genetic and Epigenetic Alterations in the von Hippel-Lindau Gene: the Influence on Renal Cancer Prognosis

Smits, K. M., Schouten, L. J., van Dijk, B. A.C., Hulsbergen-van de Kaa, C. A., Wouters, K. A.D., Oosterwijk, E., van Engeland, M., van den Brandt, P. A.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 184 KB

english, 2008

38

Follistatin Suppresses the Production of Experimental Multiple-Organ Metastasis by Small Cell Lung Cancer Cells in Natural Killer Cell-Depleted SCID Mice

Ogino, H., Yano, S., Kakiuchi, S., Muguruma, H., Ikuta, K., Hanibuchi, M., Uehara, H., Tsuchida, K., Sugino, H., Sone, S.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 619 KB

english, 2008

39

The Prognostic Significance of Serum 2 Microglobulin Levels in Acute Myeloid Leukemia and Prognostic Scores Predicting Survival: Analysis of 1,180 Patients

Tsimberidou, A.-M., Kantarjian, H. M., Wen, S., O'Brien, S., Cortes, J., Wierda, W. G., Koller, C., Pierce, S., Brandt, M., Freireich, E. J., Keating, M. J., Estey, E. H.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 322 KB

english, 2008

40

Immune Expression and Inhibition of Heat Shock Protein 90 in Uveal Melanoma

Faingold, D., Marshall, J.-C., Antecka, E., Di Cesare, S., Odashiro, A. N., Bakalian, S., Fernandes, B. F., Burnier, M. N.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 615 KB

english, 2008

41

Antiangiogenic Therapy with Mammalian Target of Rapamycin Inhibitor RAD001 (Everolimus) Increases Radiosensitivity in Solid Cancer

Manegold, P. C., Paringer, C., Kulka, U., Krimmel, K., Eichhorn, M. E., Wilkowski, R., Jauch, K.-W., Guba, M., Bruns, C. J.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 735 KB

english, 2008

42

Suppression of Lung Tumor Growth and Metastasis in Mice by Adeno-Associated Virus-Mediated Expression of Vasostatin

Cai, K. X., Tse, L. Y., Leung, C., Tam, P. K.H., Xu, R., Sham, M. H.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 1.13 MB

english, 2008